Clinical trials: Hydrocortisone
Congenital Adrenal Hyperplasia
A Study of the Efficacy, Safety and Tolerability of Chronocort in Treating CAH
Subjects completing study DIUR-005 and those who have already completed study DIUR-003 will be offered the opportunity either to continue Chronocort® therapy or to switch from their current glucocorticoid therapy to Chronocort®…
- Trial name
- NCT03062280
- Testing
- Hydrocortisone
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Neurocrine UK Limited
Implant Therapy
Assessment of Deproteinized Bovine Bone for Immediate Implants Placement in Maxillary Esthetic Zone.
: Many of studies have been performed to improve osseointegration and bone density around implants by modifying the implant by adding bone graft or substitute material that increase success of implant.
- Trial name
- Mohamed sedky (NCT07569146)
- Testing
- Immediate dental implants with bone graft augmentation (deproteinized bovine bone), Immediate dental implants without bone augmentation
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Bruxism, Stress (Psychology)
Influence Of Different Relaxation Techniques On Stress Level For Patients With Bruxism Using Salivary Biomarkers.
This study will compare the effect of three different physical therapy techniques on stress level on patients with bruxism by assessment of morning salivary biomarkers.
- Trial name
- NCT07868341
- Testing
- The Rocabado Program, Jacobson Progressive Muscle Relaxation Technique, Surface electromyography biofeedback
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Misr University for Science and Technology
Systemic Lupus Erythematosis
Circulating MicroRNAs in Understanding Pathogenesis of Systemic Lupus Erythematosis
This study aims to identify the expression signature of miR-181a, miR-196a and miR-21 in plasma of SLE patients and difference in their expression among groups with different systemic lupus erythematosis disease activity index…
- Trial name
- NCT02756546
- Testing
- Cyclophosphamide, Hydroxychloroquine, Hydrocortisone
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Autism, Autism Disorders and Maternal Stress
Adapting the Sensory Environment to Reduce Stress in Children With Autism During Dental Visits
This study aims to evaluate the impact of a sensory-adapted dental environment (SADE) on the stress levels and behavioral responses of children with autism spectrum disorder (ASD) during dental visits.
- Conditions
- Autism, Autism Disorders and Maternal Stress, Sensory Integration Disorder, Stress Biomarkers
- Trial name
- SMILED (NCT07887243)
- Testing
- Sensory-Adapted Dental Environment
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Polycystic Ovary Syndrome
Low Dose Growth Hormone in Obese PCOS Women
Study hypothesis: Growth hormone (GH), through its generation of free 'bioavailable' insulin-like growth factor (IGF)-I, can improve insulin sensitivity and the metabolic profile of women with polycystic ovary syndrome.
- Trial name
- NCT00518635
- Testing
- Nutropin
- Where
- United States
- Sponsor
- Oregon Health and Science University
Patient Admitted in Reanimation
Hydrocortisone Use After Etomidate in Intensive Care
the objective of the study is to assess the value of substitution with 200mg/24h of hydrocortisone for 48 hours for patients in intensive care who have received a single injection of etomidate
- Trial name
- NCT00862381
- Testing
- Hydrocortisone
- Where
- 2 sites in France
- Volunteers
- 106 people
- Sponsor
- University Hospital, Grenoble
Anxiety
Virtual Reality to Reduce Intraoperative Anxiety in Vasectomies Under Local Anesthesia
Vasectomy is an elective and ambulatory surgery, typically performed under local anaesthesia. The most common problem that we have found among patients is the anxiety and the apprehension to face the procedure.
- Trial name
- NCT06749353
- Testing
- Virtual reality
- Where
- Spain
- Volunteers
- 148 people
- Sponsor
- Hospital Mutua de Terrassa
Autonomous Cortisol Secretion, Mild Autonomous Cortisol Secretion (MACS)
Metyrapone for Mild Autonomous Cortisol Secretion (MACS)
The purpose of this study is to find out whether the study drug, metyrapone, is safe and effective in treating participants with Mild Autonomous Cortisol Secretion (MACS).
- Trial name
- NCT06106295
- Testing
- Metyrapone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Purpura, Thrombocytopenic, Idiopathic, Immune Thrombocytopenia
Decitabine Combining Dexamethasone Versus Dexamethasone in Management of ITP
The project was undertaking by Qilu Hospital of Shandong University and other 18 well-known hospitals in China. In order to report the efficacy and safety of decitabine combining with dexamethasone for the treatment of adults…
- Trial name
- NCT03252457
- Testing
- Decitabine, Dexamethasone
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shandong University
Sepsis, Adrenal Insufficiency
Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis
The purpose of this study is to determine if the combination of hydrocortisone plus fludrocortisone is more efficacious than hydrocortisone alone in treating adrenal insufficiency in severe sepsis.
- Trial name
- NCT00368381
- Testing
- Hydrocortisone, Fludrocortisone
- Sponsor
- CAMC Health System
Nursing Caries, Newborn Illness
The Effect of Swaddling Method on Stress Level in Newborns Administration to Nasal CPAP
Transient tachypnea of newborn (TTN) causes 42.5%-60% of non-infectious respiratory distress cases in newborns, it is seen in only 1% of all newborns.
- Conditions
- Nursing Caries, Newborn Illness, Nurse's Role
- Trial name
- NCT05657977
- Testing
- nonpharmacologic intervention (swaddling)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
Type 1 Diabetes, Stress
The Influence of Psychobiological Adversity to Children and Adolescents With Type 1 Diabetes
The aims of this study are two fold: To show whether there is an increased environmental or genetic susceptibility to stress in patients with T1D and whether it influences diabetes management.
- Trial name
- NCT02575001
- Testing
- Psychological background determinations, Genetic susceptibility determination, Cortisol release test
- Where
- Slovenia
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Jaw, Edentulous, Partially, Acquired Absence of Single Tooth
Case Selection and Treatment Protocol for Immediate Dental Implants in the Esthetic Zone
In this study a tooth that needs to be extracted will be replaced by an implant (artificial root) placed at the same appointment as the extraction.
- Trial name
- NCT02154581
- Testing
- SLActive implant
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Atopic Dermatitis, Psoriasis
Clinical, Psychological and Genetic Characteristics in Dermatological Patients
Atopic dermatitis (AD) and psoriasis (PS) are chronic, relapsing dermatological disorders with a high rate of psychiatric co-morbid pathology represented with depression.
- Trial name
- NCT03831646
- Where
- Kazakhstan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Astana Medical University
Bone Resorption After Tooth Extraction
Buccal Plate Expansion Technique Versus Guided Bone Regeneration Technique in Socket Preservation in the Aesthetic Zone.
Introduction and evaluation of a new technique for socket preservation involving internal expansion of the buccal plate of the extraction socket using internal flapless corticotomy and bone grafting the extraction socket with…
- Trial name
- NCT03065803
- Testing
- Buccal plate expansion technique for dental socket preservation, Guided bone regeneration technique for post-extraction dental socket preservation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Passant Khaled Tayaa
Depression
Hormone and Sleep Response to Antidepressant Treatment in Adolescents and Adults With Depression
This study will determine whether there are age-related differences in the body systems controlling sleep and stress hormone patterns.
- Trial name
- NCT00106197
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Uma Rao
Stress, Job, Student Burnout
Investigating the Effects of Osteopathic Manipulative Treatment on Stress Management in Medical Students
The goal of this clinical trial is to evaluate stress biomarkers, subjective stress levels, and cognitive function in medical students.
- Conditions
- Stress, Job, Student Burnout, Stress, Physiological, Stress, Psychological
- Trial name
- NCT06125574
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Stress, Physiological, Stress, Psychological
Wise Interventions and Responses to Stress
This study compares the effects of two wise interventions (implicit theory of personality intervention and implicit theory of personality intervention plus self-affirmation) with a control condition in the stress responses of…
- Conditions
- Stress, Physiological, Stress, Psychological, Social Stress, Depression
- Trial name
- ITP-RSA (NCT04786496)
- Testing
- ITP+SA Wise intervention, ITP Wise intervention, Control condition
- Where
- Spain
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Traumatic Brain Injury, Trauma
Corticosteroid Therapy for Glucocorticoid Insufficiency Related to Traumatic Brain Injury
Traumatic brained injured (TBI) patients frequently suffered from glucocorticoid insufficiency that is associated with a raise in the rate of pneumonia.
- Conditions
- Traumatic Brain Injury, Trauma, Adrenal Insufficiency, Pneumonia
- Trial name
- Corti-TC (NCT01093261)
- Testing
- Hydrocortisone Fludrocortisone
- Where
- 18 sites in France
- Volunteers
- 336 people
- Sponsor
- Nantes University Hospital
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