Clinical trials: Hydrocortisone
Fibromyalgia
Fibromyalgia and Olive Oil
We have recently reported a prothrombotic state in patients with fibromyalgia that may increase the risk of thrombosis-related cardiovascular disease in these patients.
- Trial name
- NCT04245592
- Testing
- Extra Virgin Olive Oil, Refined Olive Oil
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- University of Jaén
Acute Coronary Syndrome, Stress Hyperglycemia
Cellular Immunity, Neuroendocrine, and Inflammatory Factors for Clinical Prognosis in Acute Coronary Syndrome
In acute coronary syndrome (ACS), there is an increase in cortisol levels, as an expression of the stress response, and C-reactive protein, as an expression of the inflammatory response, which are in turn associated with changes…
- Conditions
- Acute Coronary Syndrome, Stress Hyperglycemia, Cortisol; Hypersecretion, Inflammatory Response
- Trial name
- NCT06513611
- Testing
- Serum cortisol.
- Where
- Argentina
- Volunteers
- 150 people
- Sponsor
- Hospital de Clinicas José de San Martín
Neuroendocrine Reproductive Status
Impacts of Metabolic Variation on Neuroendocrine Control of Reproduction
This study will evaluate the potential effects of a changing metabolic environment on GnRH hypothalamic neurons, by performing studies of LH pulsatility (basal and during clamp studies) in different groups of male subjects fed…
- Trial name
- NCT01058681
- Testing
- effect of metabolic variations on LH pulsatility
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Post Operative Pain, Erector Spinae Plane Block
The Effect of Local Anesthetic Infiltration or Erector Spina Plan Block on Stress Hormone Response
Laparoscopic cholecystectomy is one of the most common operations in abdominal surgery. Effective analgesia in the postoperative period; It is of great importance in terms of acceleration of recovery, prevention of atelectasis…
- Conditions
- Post Operative Pain, Erector Spinae Plane Block, Inguinal Hernia
- Trial name
- NCT05717530
- Testing
- wound site local anesthesic infiltration, Erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Missing Teeth, Teeth Replacemnt by Single Dental Implant
Randomized Controlled Clinical Trial of CAD/CAM and Conventionally Fabricated Singl Implant Abutments.
CAD/CAM technology has been introduced to the field of implant dentistry in the beginning of 1990's (Priest 2005). Since their introduction, the use of CAD/CAM technology in the production of dental implant restorations has been…
- Conditions
- Missing Teeth, Teeth Replacemnt by Single Dental Implant, Zirconia Abutment, Titanium Abutment
- Trial name
- NCT01229995
- Testing
- dental implants - zirconia abutmetns - prefabricated abutments
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Agoraphobia; Panic, Social Anxiety Disorder
Differential Effects of in Vivo and Virtual Exposure Therapy in Agoraphobia
Anxiety disorders, including agoraphobia, are prevalent in the German population, leading affected individuals to avoid specific places like crowds or public transport.
- Trial name
- VRExpo (NCT06514495)
- Testing
- Therapy
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Implant Tissue Failure
One-abutment One-time for Immediate Restoration Procedure in the Esthetic Zone
Objectives: The aim of this randomized control trial was to compare immediate restoration procedure with a one abutment one-time technique using a conventional versus full digital workflow.
- Trial name
- IONE (NCT04139512)
- Testing
- guided surgery, conventionnel implant placement
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Liege
Pain
The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Biomarkers After Rotator Cuff Repair
The present study was designed to test the hypothesis that dexmedetomidine added to ropivacaine for interscalene brachial plexus blocks for elective shoulder surgery would enhance the duration and effect of analgesia when…
- Trial name
- NCT02766556
- Testing
- dexmedetomidine, ISB, Ropivacaine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Food Addiction, How Opioid Tone Was Related to Self Reported
Stress, Hormones, and Eating
The investigators will develop a measure of endogenous opioid tone that might serve as a biological marker for drive for palatable food.
- Conditions
- Food Addiction, How Opioid Tone Was Related to Self Reported, Drive to Eat Using a Measure of Food Addiction
- Trial name
- SHE (NCT01175512)
- Testing
- Naltrexone
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Single Effort in Air Temperature of Minus 10°C
Exercise in the cold is an attractive option for many athletes. Erythrocyte aggregation, as one of the main rheological parameters, constitutes an important indicator of microcirculation and oxygen transport capacity in the human…
- Trial name
- NCT07664072
- Testing
- cold, neutral
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Myeloid Neoplasm
Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms
The purpose of this study is to learn the effects of treatment with an investigational drug, CPX-351 in patients with secondary myeloid neoplasms (SMNs).
- Trial name
- NCT05656248
- Testing
- CPX-351, MHA, Allogeneic Hematopoietic Stem Cell Transplantation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- St. Jude Children's Research Hospital
Implant Therapy, Class II Extraction Sockets
Customized CAD/CAM Titanium-Milled Abutments Vs. Custom Abutments Over Immediate Implants in Class II Extraction Sockets in the Esthetic Zone: a Randomized Controlled Clinical Trial
Background: Immediate implant placement in esthetic zones, particularly Class II and III extraction sockets, presents challenges related to soft and hard tissue changes post-extraction.
- Trial name
- NCT06791655
- Testing
- Stock Abutment Implant, Customized CAD CAM Titanium Milled Abutment Implant
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams University
Salivary Cortisol, Salivary Alpha Amylase
Evaluating the Effects of Psychological Stress on Salivary Biomarkers in Pediatric Patients Visiting Pediatric and General Dental Clinic
the goal of this study is to test the effect of psychological stress on pediatric patients visiting specialized and general dental clinic by measure salivary cortisol and salivary alpha amylase and by use children fear survey…
- Trial name
- NCT06917976
- Testing
- to compare the effect of environment and attitude of dentist in children visiting specialized pediatric dental clinic and general dental clinic .
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Alveolar Bone Loss, Esthetic Zone Implant Rehabilitation
Immediate Implant Placement With Autogenous Maxillary Tuberosity Graft in the Esthetic Zone
Immediate implant placement in the esthetic zone is often associated with buccal bone deficiency, which may compromise esthetic outcomes and long-term implant stability.
- Trial name
- TUBERO-IMPLANT (NCT07460076)
- Testing
- Immediate Implant Placement With Maxillary Tuberosity Autogenous Graft
- Where
- Vietnam
- Volunteers
- 15 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come back (relapsed).
- Trial name
- NCT04546399
- Testing
- 3-Dimensional Conformal Radiation Therapy, Asparaginase Erwinia chrysanthemi, Biospecimen Collection
- Where
- 227 sites in United States, Australia and 2 more
- Volunteers
- 461 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining hormone therapy with chemotherapy and androgen suppression may kill more tumor cells.
- Trial name
- NCT00002855
- Testing
- Bicalutamide, Doxorubicin hydrochloride, Estramustine Phosphate Sodium
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- M.D. Anderson Cancer Center
Stress, Burnout, Professional
Using Yogic Breathing to Reduce Stress in Anesthesia Personnel As Measured by Hair Cortisol
Mind body exercises have long been used as a way for individuals to reduce stress and improve well-being. Recent studies indicate that yogic breathing (YB, also known as pranayama) could potentially impact both the mind and body…
- Trial name
- NCT04858815
- Testing
- yogic breathing
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Partial Mineralocorticoid Deficiency
Impact of the Administration of Fludrocortisone in Very Premature Infants
Water and electrolytic homeostasis is remarkably controlled by the mineralocorticoid pathway (renin-angiotensin-aldosterone system acting on the renal tubule).
- Trial name
- MINIPREM (NCT03001089)
- Testing
- Oral Fludrocortisone (enteral)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebrovascular Stroke
The Correlation Between Hair Cortisol Level of Acute Stroke or Its Long Term Disability.
In patients admitted to hospital with acute cerebrovascular stroke, we want to study the relationship between hair cortisol levels and biomarkers of inflammation and the clinical and radiological severity of the stroke and the…
- Trial name
- NCT02587949
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Bnai Zion Medical Center
Healthy Adult Male Volunteers
Evaluation of Systemic Bioavailability and Effects on 24-Hour Plasma Cortisol Profile of 6 mg Delivered Once Daily Versus 3 mg Delivered Twice Daily in Healthy Adult Male Volunteers
Single-centre, randomized, double-blind, two-period, two-sequence, cross-over 7-day study. This study is the first safety/tolerability evaluation of a product -suppository formulation containing 6 mg BDP (once daily dosing), a…
- Trial name
- NCT04873063
- Testing
- Beclomethasone dipropionate
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- SOFAR S.p.A.
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