Clinical trials: Hydrocortisone
Severe Sepsis
Hydrocortisone for Prevention of Septic Shock
Severe sepsis is a disease with a high mortality. Development of shock is a most serious complication and increases the risk of death considerably.
- Trial name
- HYPRESS (NCT00670254)
- Testing
- Hydrocortisone
- Where
- 30 sites in Germany
- Volunteers
- 380 people
- Sponsor
- Charite University, Berlin, Germany
Overtraining Syndrome
Changes in the Hormonal and Inflammatory Profile of Young Sprint- and Endurance-trained Athletes.
One essential element of athlete training is conditioning camps, where athletes undergo a rigorous and targeted training schedule to prepare for upcoming sporting events.
- Trial name
- CHIPYA (NCT06150105)
- Testing
- Exercise training
- Where
- Poland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Somatic Symptom Disorder (DSM-V)
Effect of Venlafaxine Versus Dosulepin in Pain Predominant Somatic Symptom Disorder
Somatic symptom disorder (SSD) is marked by persistent physical complaints, often involving pain, alongside excessive thoughts or behaviors related to health, which substantially disrupt daily functioning.
- Trial name
- NCT06803485
- Testing
- Venlafaxine, Dosulepin
- Where
- India
- Volunteers
- 84 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Cushing's Disease
Cushing's Disease Complications
This study aims at investigating the complications of Cushing's disease in "de novo" patients. A series of investigations will assay before treatment and every year thereafter during a 3 years follow-up period the various…
- Trial name
- COMPLICUSHING (NCT02568982)
- Testing
- Exams and questionnaires
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Occupational Stress
Stress Biomarkers Leading to Professional Burnout Among People Involved in a Mobile Intensive Care Unit During the COVID-19 Pandemic
This study is aiming at investigating whether professional burnout in people involved in the mobile intensive care unit (in French: Element Mobile de Réanimation, EMR) in Mulhouse (France) can be predicted upstream by a low…
- Trial name
- AUTONOMIC (NCT04365335)
- Testing
- Assessment of work-related stress, Saliva sample collection, Cardiac and electrodermal recordings
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Healthy
Effect of Hydrocortisone on the Brain
The purpose of this study is to use brain imaging technology to examine the effect of the hormone hydrocortisone on the brain's response to various facial expressions.
- Trial name
- NCT00055003
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Mental Health (NIMH)
Caregiver Stress Syndrome, Reiki
The Effect of Reiki on the Stress Level of Caregivers of Cancer Patients
Stress caused by late-identified and unmet needs of caregivers negatively affect the physical and emotional health of patients and caregivers as well as their compliance with the treatment.
- Conditions
- Caregiver Stress Syndrome, Reiki, Caregiver Burnout
- Trial name
- NCT04461873
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Diffuse Large B-cell Lymphoma
New Combination of Chemoimmunotherapy for Systemic B-cell Lymphoma With Central Nervous System Involvement
This is an open, non comparative, multicentre phase II trial, to evaluate the efficacy and feasibility of a new sequential combination of HD-MTX-AraC-based chemoimmunotherapy, followed by R-ICE regimen, and by high-dose…
- Trial name
- NCT02329080
- Testing
- Methotrexate, Rituximab, Cytarabine
- Where
- 36 sites in Czechia, Italy and 2 more
- Volunteers
- 79 people
- Sponsor
- International Extranodal Lymphoma Study Group (IELSG)
Obstructive Sleep Apnea, Sleep Apnea
Inflammation and Neurocognitive Damage Markers in Elderly People With Obstructive Sleep Apnea
The aging process tends to promote an overall increase in inflammation compromising the immunologic system regulation, sleep/wakefulness pattern, and neurocognitive performance.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Apnea, Obstructive, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT04882020
- Testing
- cortisol, BDNF, s100B, IL-1B, IL-6, IL-10, TNF-alpha
- Where
- Brazil
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Burns
Low-dose Hydrocortisone in Acutely Burned Patients
Major burns trigger the release of circulating mediators, as cytokines and endotoxin that induces a systemic inflammatory response syndrome. The cardiovascular effects are similar to those seen in septic shock.
- Trial name
- NCT00149123
- Testing
- hydrocortisone 200 mg/day
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Autism Spectrum Disorder
Effects of Mounted vs Unmounted Human-Equine Interaction on Autistic Youth
The goal of this clinical trial is to learn how interacting with horses affects autistic children and youth. The main questions it aims to answer are: How does interacting with horses affect cortisol, heart-rate variability, and…
- Trial name
- NCT07897123
- Testing
- Mounted Human-equine Interaction, Unmounted Human-equine Interaction, No-Horse Control
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Colorado State University
Major Depressive Disorder
Light Therapy for Elderly Depression
The purpose of this study is to investigate the following two hypotheses: 1. Treatment with bright light improves their sleep, mood, concentration and self-sufficiency of elderly depressed subjects.
- Trial name
- NCT00332670
- Testing
- 10.000lux blue 1 hour every day during three weeks, 50lux dim red 1 hour every day during three weeks
- Where
- Netherlands
- Volunteers
- 89 people
- Sponsor
- GGZ Buitenamstel
Rheumatoid Arthritis
Can Cytokines be Used as an Activation Marker
RA is a chronic, autoimmune, inflammatory disease that involves small joints in the form of symmetrical polyarthritis and progresses with exacerbations and remissions.
- Trial name
- NCT04486027
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Asthma in Children
Comparison of Combination of Beclomethasone Dipropionate and Formoterol Fumarate Versus Single Components Assessed by Knemometry and Urinary Cortisol Measurements in Asthmatic Children
single center, double-blind, double-dummy, 2-way cross over study in asthmatic children already treated with inhaled corticosteroids
- Trial name
- NCT01658891
- Testing
- combination of beclomethasone dipropionate 50µg + formoterol fumarate 6µg, free combination of beclomethasone dipropionate 100µg + Formoterol fumarate 6µg
- Where
- Denmark
- Sponsor
- Chiesi Farmaceutici S.p.A.
Posttraumatic Stress Disorder
Neural and Pharmacological Correlates of Intrusions in Patients With Posttraumatic Stress Disorder
There is evidence that glucocorticoids have an impact on intrusive memories in patients with posttraumatic stress disorder (PTSD).
- Trial name
- NCT01108133
- Testing
- 10 mg HydrocortisoneHöchst, Dexamethasone
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Intussusception
Effect of Hydrocortisone on Improving Outcome of Pneumatic Reduction of Infantile Intussusception
Intussusception is one of the most frequent causes of acute bowel and second most common cause of acute abdominal pain in pediatric age .95 % of cases are idiopathic, the rest are either due to pathological lead point or post…
- Trial name
- NCT02691858
- Testing
- Hydrocortisone, Saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Viral Haemorrhagic Fever, Dengue Fever
Chinese and Western Medicine Treatment of Fever Associated With Bleeding Symptoms
To meet eligibility criteria, this study and informed consent of the syndrome of fever associated with bleeding of infectious diseases, severe patients to carry out multicenter, practical randomized controlled clinical research…
- Trial name
- NCT01973855
- Testing
- Western Medicine, TCM and Western Medicine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Guangzhou 8th People's Hospital
Sepsis, Septic Shock
Adjunctive Fludrocortisone in Septic Shock
Sepsis is a life-threatening condition caused by the body's dysregulated response to an infection. While corticosteroids are known to help stabilize blood pressure in septic shock, their ability to reduce mortality is still…
- Conditions
- Sepsis, Septic Shock, Sepsis - to Reduce Mortality in the Intensive Care Unit, Sepsis and Septic Shock
- Trial name
- AFLUDROS-1 (NCT07451886)
- Testing
- Fludrocortisone 100 mcg daily
- Where
- 5 sites in Hong Kong
- Volunteers
- 32 people
- Sponsor
- Chinese University of Hong Kong
Emotion
Evaluation of Emotion-related Salivary Molecular Biomarkers
Recent studies show that emotional states can be discriminated by physiological responses. This physiological regulation results from the action of enzymes and hormones that represent the activity of the autonomic nervous system.
- Trial name
- EMJOY (NCT07320040)
- Testing
- Identication and measurement of a molecular biomarkers signature
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sys2Diag
Major Depression
Mineralocorticoid Receptor, NMDA Receptor and Cognitive Function in Depression
The steroid hormone cortisol is released in response to stress and acts in the central nervous system upon glucocorticoid (GR) and mineralocorticoid receptors (MR).
- Trial name
- MISO (NCT03062150)
- Testing
- Fludrocortisone, D-Cycloserine
- Where
- Germany
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
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