Clinical trials: Hydrocortisone
Acute Myeloid Leukemia
Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies
PRIMARY OBJECTIVE: This is a pilot study to characterize the toxicity profile, to determine the maximum tolerated dose of the combination of crenolanib and sorafenib, and to determine the feasibility of administering these drugs…
- Trial name
- NCT02270788
- Testing
- Crenolanib, Sorafenib, methotrexate, hydrocortisone and cytarabine with leucovorin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St. Jude Children's Research Hospital
Primary Aldosteronism, Autonomous Cortisol Secretion
68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Diagnosing Unilateral Subtype of Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion (PREDICT)
To validate the accuracy of 68Ga-Pentixafor PET/CT and adrenal venous sampling (AVS) in subtype diagnosis of PA/ACS patients with adrenal nodules, based on biochemical and clinical remission outcomes, and to determine whether the…
- Trial name
- NCT06833437
- Testing
- 68Ga-Pentixafor PET/CT, AVS
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Qifu Li
Smokers
Effect of Behavioral Training on Physiological Responses to Smoking Cues, Affect and Cortisol
This study is ancillary. Participants will be recruited as part of a separate clinical trial on effects of two intensive behavioral training programs that evaluates feasibility and efficacy of a behavioral treatment that includes…
- Trial name
- physio (NCT01362101)
- Testing
- Mindfulness behavioral intervention (MT),cognitive behavioral intervention (CBT)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- A. Eden Evins
Reumatoid Arthritis, Corticosteroids Adverse Reaction
Prevalence of Adrenal Insufficiency and Associated Factors in Rheumatoid Arthritis Patients Using Low-dose Corticosteroids.
This study aims to investigate the prevalence of adrenal insufficiency in rheumatoid arthritis (RA) patients receiving low-dose corticosteroid therapy and to identify the factors influencing adrenal insufficiency.
- Conditions
- Reumatoid Arthritis, Corticosteroids Adverse Reaction, Adrenal Insufficiency
- Trial name
- NCT07866326
- Testing
- ACTH stimulation test, Cortisol
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Sepsis
Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis
Main objective and primary endpoint: To compare the effect hydrocortisone plus fludrocortisone vs. placebo on a composite of death or persistent organ dysfunction - defined as continued dependency on mechanical ventilation, new…
- Trial name
- RECORDS (NCT04280497)
- Testing
- Administration procedures
- Where
- France
- Volunteers
- 1,800 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Therapeutic Touch, Cancer
Reiki for Cancer: Pain, Anxiety, and Stress
The goal of this clinical trial is to investigate the effects of Reiki, Sham Reiki, and Progressive Relaxation Exercise on the levels of pain, anxiety, and stress in cancer patients.
- Trial name
- NCT06296680
- Testing
- Reiki, Progressive Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Ege University
Pulmonary Disease, Chronic Obstructive
A Study to Assess the Effects of Repeat Doses of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Severe Impairment.
This study will assess the saftey of giving fluticasone furoate 200mcg/GW642444M 25mcg once daily for 7 days to patients with severe renal imparement.
- Trial name
- NCT01266980
- Testing
- Inhaled FF/ GW642444M (200/25mcg)
- Where
- Czechia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
PTSD
Circadian Influence on Prolonged Exposure Therapy for PTSD
Proposed research will examine time-of-day effects on trauma-related fear extinction using Prolonged Exposure Therapy (PE) telemedicine for Posttraumatic Stress Disorder (PTSD) in the National Center for PTSD (NCPTSD).
- Trial name
- NCT05453162
- Testing
- Prolonged Exposure Therapy for Posttraumatic Stress Disorder
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Massachusetts General Hospital
Laminectomy, Post-laminectomy Syndrome
Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Traditionally, pain relief through spinal cord stimulation has been associated with the appearance of paresthesia in the affected area.
- Conditions
- Laminectomy, Post-laminectomy Syndrome, Spinal Cord Syndrome, Failed Back Surgery Syndrome
- Trial name
- NCT03702010
- Testing
- spinal cord stimulation conventional, spinal cord stimulation experimental
- Where
- 2 sites in Spain
- Volunteers
- 27 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Fibromyalgia (FM)
Effects of Immersive Virtual Reality in Fibromyalgia
Fibromyalgia is considered a disease of unknown etiology, which It affects between 2 to 5% of the population in developed countries, mostly women, diagnosed mainly between 40 and 50 years of age, and whose main characteristic is…
- Trial name
- NCT06658223
- Testing
- Exercise with virtual reality
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad San Sebastián
Crohn Disease
Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult
The pathogenesis of Crohn Disease (CD) is unknown, but there is evidence show that the inadequate immune response or overreaction of the immune system against food antigens or components of the commensal flora involve it.
- Trial name
- EN (NCT02056418)
- Testing
- enteral nutrition, corticosteroid
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Hemiarthroplasty, Arthroplasty, Replacement, Hip
Effects of Surgery Start Time on Postoperative Interleukin-6, Interleukin-8, and Cortisol
Cortisol is a hormone that increases after trauma or surgery and has circadian rhythm. It has a form that is increased in the morning and decreased in the evening.
- Trial name
- NCT03076827
- Testing
- Total hip replacement, Hemi-arthroplasty
- Volunteers
- 44 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Healthy
Is the Diurnal Variation in Circulating Levels of Cortisol Reflected in Follicular Fluid of Preovulatory Follicles Close to Ovulation?
Glucocorticoids and especially cortisol exhibit a pronounced diurnal variation. Levels peak around 8 am and may decrease around two to three times during the day reaching a nadir during the evening and early in the night.
- Trial name
- NCT06877429
- Testing
- Time of OPU
- Where
- United Arab Emirates
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Hyperaldosteronism
SPARTACUS: Subtyping Primary Aldosteronism: a Randomized Trial Comparing Adrenal Vein Sampling and Computed Tomography Scan.
Rationale: Primary hyperaldosteronism (PA) is the most frequent form of secondary hypertension. In PA autonomous hypersecretion of aldosterone by one or both adrenal glands causes hypertension that is often refractory to…
- Trial name
- SPARTACUS (NCT01096654)
- Testing
- Ct-scan or adrenal vein sampling
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Radboud University Medical Center
Psychological Stress, Mindfulness
Mechanisms of Mindfulness Training and Stress Reduction
This study is a three-arm randomized controlled trial of a mindfulness stress reduction intervention, with the aim of dismantling the experience-monitoring and nonjudgmental-acceptance elements of mindfulness programs to…
- Trial name
- NCT02502227
- Testing
- Mindfulness
- Where
- 3 sites in United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Stress, Psychological
Reward Under Stress: Effects of a Multidimensional Stress Prevention Program in University Students
The purpose of this study is to investigate the effects of a multidimensional stress prevention program on psychological and physiological indicators among university students.
- Trial name
- NCT03861013
- Testing
- Multidimensional stress prevention program (GeDStress)
- Where
- Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chantal Martin Soelch
Vasoplegia, Cardiac Surgery
Low Dose Corticosteroid Infusion in Vasoplegia After Cardiac Surgery (CORTIVAS-CS)
Vasoplegia is an important determinant for adverse postoperative outcome and is observerd in 5% to 54% of patients undergoing cardiac surgery using cardiopulmonary bypass (CPB).
- Trial name
- CORTIVAS-CS (NCT04301479)
- Testing
- hydrocortisone sodium succinate, Saline
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Instituto do Coracao
Septic Shock, Sepsis
Triple Therapy in Septic Shock Patients
this study is conducted to evaluate the role of the novel triple therapy combination in reducing the mortality rate, reducing the shock time, and reversal of organ damage.
- Conditions
- Septic Shock, Sepsis, Organ Dysfunction Syndrome Sepsis
- Trial name
- NCT04508946
- Testing
- vitamin c - thiamine- hydrocortisone
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Air Force Specialized Hospital, Cairo, Egypt
Leukemia, Lymphoma
Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00002494
- Testing
- cyclophosphamide, cytarabine, dexamethasone
- Where
- 23 sites in United States
- Volunteers
- 134 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Long-COVID, Post-acute COVID-19 Syndrome
Effectiveness of Non-invasive Neuromodulation in Patients With Long-COVID
Sleep quality and duration are critical to cognitive, emotional and physical well-being, and poor sleep quality has been associated with an increased risk of cognitive, psychological and cardiometabolic disorders.
- Trial name
- NCT06456502
- Testing
- Non-invasive neuromodulation
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad Rey Juan Carlos
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.