Clinical trials: Hydrocortisone
End-Stage Renal Disease, Hemodialysis Complication
Effects of Mindfulness Meditation on Hemodialysis Patients
Objective: This study aimed to examine the effects of mindfulness meditation on the quality of sleep, perceived stress, serum cortisol, and C-reactive protein in end-stage renal disease patients undergoing hemodialysis.
- Trial name
- RCT (NCT06936293)
- Testing
- Mindfulness Meditation
- Where
- Kuwait
- Volunteers
- 56 people
- Sponsor
- University of Jordan
Prurigo Nodularis
Evaluation of the Antipruritic Effect of Elidel (Pimecrolimus) in Non-atopic Pruritic Disease
The development of the topical calcineurin inhibitor pimecrolimus resulted in a significant improvement in the treatment of atopic dermatitis. In addition, an excellent amelioration of pruritus could be regularly observed.
- Trial name
- CASM981CDE21 (NCT00507832)
- Testing
- Pimecrolimus, Hydrocortisone
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Muenster
Depression
Fludrocortisone and Information Processing in Healthy Volunteers
Stimulating the mineralocorticoid receptor (MR) may restore a disturbed balance as seen in depression. In this double-blind, randomized, placebo-controlled trial the investigators will test the effects of a single dose (500mg)…
- Trial name
- NCT01648998
- Testing
- Fludrocortisone
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Substance Abuse Disorders
Study of Smoking Abstinence
Background: Relapse following cigarette abstinence remains a common problem for smokers who are attempting to quit. Most research has focused on the acute withdrawal phase that occurs within the first 48 hours to 1 week after…
- Trial name
- NCT01035632
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Idiopathic Sudden SNHL
Predictive Factors for Recovery in Idiopathic Sensory Neural Hearing Loss
Sudden sensorineural hearing loss (SSNHL) is an otological emergency that is defined as a hearing loss greater than 30 dB over three consecutive frequencies within 72 hours, with abnormalities of the cochlea, auditory nerve, or…
- Trial name
- NCT05112354
- Testing
- systemic and intratympanic injection of steoid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
PTSD, Acute Stress Disorder
PTSD Prevention Using Oral Hydrocortisone
There is currently no evidence-based intervention for individuals exposed to trauma that is designed to aid recovery and prevent the development of post-traumatic stress disorder (PTSD).
- Conditions
- PTSD, Acute Stress Disorder, Trauma-related Stressor
- Trial name
- NCT04924166
- Testing
- Hydrocortisone
- Where
- 3 sites in United States, Israel
- Volunteers
- 201 people
- Sponsor
- Rachel Yehuda
Pregnancy Related, Cannabis Use
Effects of Pregnancy-associated Hormones on THC Metabolism in Women
Cannabis use is prevalent among pregnant women, but the effects of use on both the developing fetus and pregnant woman are unknown.
- Trial name
- PrECEPT (NCT04374773)
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cardiac Arrest
Vasopressin, Epinephrine, and Steroids for Cardiac Arrest
The simultaneous activation of adrenergic and vasopressin receptors, in conjunction with a potential steroid-mediated enhancement of the vascular reactivity to epinephrine may have beneficial effects in patients with cardiac…
- Trial name
- VSE-2 (NCT00729794)
- Testing
- Vasopressin, Epinephrine, Methylprednisolone, Hydrocortisone
- Where
- 3 sites in Greece
- Volunteers
- 300 people
- Sponsor
- University of Athens
Pregnancy Complications, Mental Health Issue
Psychobiological Interventions in Pregnancy
This randomized control trial will evaluate whether a physical activity intervention can improve mental health and biologic markers of stress in pregnant people with depressive or anxiety symptoms.
- Conditions
- Pregnancy Complications, Mental Health Issue, Depression, Anxiety, Pregnancy, High Risk
- Trial name
- PIP (NCT06430853)
- Testing
- Step count goal, Actigraph watch
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Stanford University
Headache
Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache
Fifty patients of both sex, aged 18-50 years and ASA I and II undergoing elective lower abdominal and pelvic surgery under spinal anesthesia were included in this randomized double-blind study.
- Trial name
- NCT02760862
- Testing
- hydrocortisone 100mg., mannitol 20% intravenous fluid
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Atopic Dermatitis
A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
The objective of this study is to assess the efficacy and safety of upadacitinib combined with topical corticosteroids (TCS) for the treatment of adolescent and adult participants with moderate to severe atopic dermatitis (AD)…
- Trial name
- AD Up (NCT03568318)
- Testing
- Upadacitinib, Topical corticosteroids (TCS)
- Where
- 193 sites in United States, Australia and 22 more
- Volunteers
- 1,533 people
- Sponsor
- AbbVie
Stress, Psychological
The Effect of Supportive Nursing Interventions of Mothers of Infants in Neonatal Intensive Care Unit
Objective: This study was conducted to determine the effects of supportive interventions on the stress levels of mothers of infants hospitalized in the Neonatal Intensive Care Unit (NICU).
- Trial name
- NCT04830150
- Testing
- Supportive interventions on the stress levels of mothers of infants hospitalized in the Neonatal Intensive Care Unit (NICU).
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Ordu University
Intertrigo
Tapioca Starch Stimutex AS, Aloe Barbadensis, Rose Hip Oil, Allantoin Comparing With Topical 1% Hydrocortisone Cream
A randomized controlled trial of efficiency and safety of liquid powder containing tapioca starch stimutex AS, aloe barbadensis, rose hip oil and allantoin comparing with topical 1% hydrocortisone cream for the treatment of…
- Trial name
- NCT04325490
- Testing
- Liquid powder, Hydrocortisone cream 1%
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Interleukin-6, Cortisol
Effectivity of Bilateral Transversus Thoracis Muscle Plane Block After Open Heart Surgery
This Study aimed to assess The Effectivity of Bilateral Transversus Thoracis Muscle Plane Block to Reduce Pain and Stress Response After Open Heart Surgery
- Trial name
- NCT04544254
- Testing
- Bilateral transversus thoracis muscle plane block, Control
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Aging
Neuroimaging Study of Exercise and Memory Function
The investigators are examining the effects of exercise and cardiovascular fitness on cognitive processes, brain function, and the amount of several proteins in the blood.
- Trial name
- EMF (NCT02057354)
- Testing
- Aerobic Exercise, Non-Aerobic Exercise
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Boston University
Sepsis
Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study
Severe bacterial infections affecting multiple body organs, called severe sepsis (including meningococcal sepsis), remain an important cause of death and disability among children.
- Trial name
- StePS (NCT00732277)
- Testing
- hydrocortisone
- Where
- 3 sites in United Kingdom
- Volunteers
- 21 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
CAH - Congenital Adrenal Hyperplasia
Hydrocortisone Modified-release in Adults: Real-world Monitoring of Longitudinal Outcomes in coNgenital Adrenal hYperplasia
Classic congenital adrenal hyperplasia (CAH) is an autosomal recessive genetic disorder caused by a defect in the enzyme cascade regulating adrenal steroidogenesis; in approximately 95% of cases the defect is located in CYP21A2…
- Trial name
- HARMONY (NCT07622030)
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Autonomous Cortisol Secretion, Adrenal Incidentaloma
Performances on Cognitive Functions and Brain Function and Follow-up After Different Treatments in Patients With Autonomous Cortisol Secretion: a Single-center, Prospective, Observational Study
This is a single center, prospective, observational study to explore and evaluate the differences on cognitive function and brain function by functional-MRI in autonomous cortisol secretion patients, and the different treatments…
- Conditions
- Autonomous Cortisol Secretion, Adrenal Incidentaloma, Non-functioning Adrenal Adenomas
- Trial name
- NCT05357456
- Testing
- Cognitive function assessment; functional magnetic resonance imaging, laparoscopic adrenal surgery
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Osteoporosis, Bullous Pemphigoid
Influence of Dermocorticoids on Bone Mineral Density in Patients With Bullous Pemphigoid
Bullous pemphigoid is the most common type of bullous skin disease and is clinically characterized by clear-tense bullae, which result in post-bullous cutaneous erosions, altering the skin barrier.
- Trial name
- DERMOS (NCT03926377)
- Testing
- bone densitometry, blood test, radiographs of the thoracic and lumbar spine
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Infant, Premature, Infant, Very Low Birth Weight
Testosterone and Cortisol Levels in Infants
Very low birth weight (VLBW) infants have more health and developmental problems than normal birth weight full-term infants. These problems are more common in males than female VLBW preterm infants.
- Trial name
- NCT02599545
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
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