Clinical trials: Hydrocortisone, completed
Sleep, Mood
Tryptophan Supplementation to Improve Night Shift Workers' Health
This randomized cross-over double-blinded trial aims to investigate the health effect of oral l-tryptophan supplementation on workers who rotate night shift work, and to examine the influences of different frequencies and timings…
- Conditions
- Sleep, Mood, Burnout, Melatonin Deficiency
- Trial name
- NCT04505800
- Testing
- Tryptophan supplement, Maltose
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Pharmacodynamics, Healthy Subjects
A Study to Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects
This is a Phase I, Randomized, Single-Blind, Crossover Study to Assess the Pharmacodynamics of AZD9977 following Single-Dose administration to healthy male subjects
- Trial name
- NCT02532998
- Testing
- AZD9977 oral suspension, Fludrocortisone, tablets, Eplerenone, tablets
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
HIV Infections, Diffuse Large B Cell Lymphoma
LINFOTARGAM: Treatment With Chemotherapy Plus Rituximab and Highly Active Antiretroviral Therapy in Patients With Diffuse Large B Cell Lymphoma and Infection With the Human Immunodeficiency Virus (HIV)
Main objective: To evaluate the applicability of the treatment: 1. To evaluate the treatment toxicity according to the Common Terminology Criteria (CTC) version 3.0 of the National Cancer Institute (NCI). 2.
- Trial name
- LINFOTARGAM (NCT00466258)
- Testing
- R-CHOP, Highly active antiretroviral therapy, Central nervous system (CNS) prophylaxis
- Where
- 15 sites in Spain
- Volunteers
- 50 people
- Sponsor
- PETHEMA Foundation
Congenital Adrenal Hyperplasia, Adrenal Insufficiency
An Open Label Study in Healthy Volunteers to Compare Chronocort® to Hydrocortisone
This was an open label, randomized, single dose, three period crossover pharmacokinetic study of Chronocort® in 30 healthy male volunteers. The study was conducted in smaller sub groups (Group 1, n=18 and Group 2, n=12).
- Trial name
- NCT03019614
- Testing
- Hydrocortisone, Chronocort
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neurocrine UK Limited
Depression, Sleep
The Long-term Effects of Body-mind-spirit Group Therapy
Aims and objectives: This study aims to examine the effects of the body-mind-spirit group therapy on marital close relationships, sleeping quality, depression, quality of life, meaning of life, and salivary cortisol levels in…
- Trial name
- NCT01727635
- Testing
- body-mind-spirit group therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Premenstrual Syndrome
Effect of Aerobic Exercise on Diurnal Cortisol Pattern in Premenstrual Syndrome
The aim of this study will be to investigate the effect of aerobic exercise on diurnal cortisol pattern in premenstrual syndrome.
- Trial name
- NCT05507255
- Testing
- Relaxation training, An aerobic exercise program
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Opioid-use Disorder, Neonatal Abstinence Syndrome
MOM NEST Study: Maternal Opioid Medication: Naltrexone Efficacy Study
This is a multi-center prospective comparative cohort study examining the safety, efficacy, pharmacokinetics, and pharmacogenomics of naltrexone for pregnant women with opioid use disorder.
- Conditions
- Opioid-use Disorder, Neonatal Abstinence Syndrome, Pregnancy, High Risk, Alcohol Use Disorder
- Trial name
- NCT03718104
- Testing
- Pharmacokinetic analysis, Safety and Efficacy, Genetic and epigenetic analysis
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Boston Medical Center
Menopause, Depression
Depression, Aging, Stress and Heart Health Study
Depression is a known risk factor for cardiovascular disease (CVD), and this comorbidity contributes significantly to the morbidity and mortality of women.
- Conditions
- Menopause, Depression, Heart Disease in Women, Stress
- Trial name
- DASHH (NCT05570721)
- Testing
- Trier Social Stress Test
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Preoperative Anxiety, Cesarean Delivery
Video Versus Verbal Preoperative Education in Elective Cesarean Delivery
This prospective randomized controlled trial aims to evaluate the effects of verbal and video-based preoperative education on anxiety levels and serum cortisol response in women scheduled for elective cesarean delivery under…
- Conditions
- Preoperative Anxiety, Cesarean Delivery, Stress Response
- Trial name
- VIDEO-CS (NCT07647601)
- Testing
- Video-Based Preoperative Education, Verbal Preoperative Education
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Individuality
Effects of Hydrocortisone on Social Cognition and Memory
The effects of hydrocortisone on cognition will be investigated.
- Trial name
- CORT-COG (NCT02478021)
- Testing
- Hydrocortisone
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Older People
Emotional Intelligence and Relaxation Techniques for Mental Health and Sleep in Older Adults
This topic highlights the role of emotional intelligence and relaxation techniques in enhancing mental health for adults over 60.
- Trial name
- NCT06671574
- Testing
- Emotional intelligence and Relaxation techniques
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- University of Jaén
Type D Personality, Trauma, Psychological
The Efficacy of a Psychosomatic Intervention
This study examines the efficacy of a psychosensory intervention in relation to: Resilience, Type D personality, and physiological effects (on blood pressure, heart rate and salivary cortisol) in a group of people who have…
- Trial name
- NCT03568591
- Testing
- Psychosensory Therapy
- Where
- United Kingdom
- Volunteers
- 125 people
- Sponsor
- Cardiff Metropolitan University
Semi Seated Position, Side Lying Position
Semi-seated Holding Position to Reduce Stress Responses in in the Neonatal Intensive Care Unit
This study to compare half semi seated position and side lying position with cortisol level on the neonate's stress respon
- Trial name
- NCT06312007
- Testing
- Semi seated position, side lying position
- Where
- Indonesia
- Volunteers
- 45 people
- Sponsor
- Hasanuddin University
Obesity
Investigating the Central and Peripheral Mechanisms by Which Glucocorticoids Affect Hunger
The purpose of this study is to examine if glucocorticoids will change neural activation in regions of the corticolimbic-striatal system that regulate feeding.
- Trial name
- NCT02722200
- Testing
- hydrocortisone, saline
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Glioblastoma (GBM)
Effect of stRess and exeRcize on the Outcome After Chemo-Radiation
Glioblastoma (GBM) is a highly malignant, incurable primary brain tumor. Due to the nature of this disease and the extent of the treatment (surgery followed by chemoradiation according to the Stupp trial) patients undergo…
- Trial name
- ERROR (NCT05431348)
- Testing
- Smartwatch, Serum Cortisol, Questionnaires
- Where
- 2 sites in Netherlands
- Volunteers
- 42 people
- Sponsor
- Maastricht Radiation Oncology
Rheumatic Diseases
Patient Self-administration of Cortisol for Cortisol-responding Disorders in Men and Women Over the Age of 17
Participants diagnosed as having fibromyalgia, osteoarthritis, and rheumatoid arthritis are to be brought to a minimum symptom state using a 3-week period during which they are to ingest modest doses of cortisol tablets with…
- Trial name
- NCT03558971
- Testing
- Cortisol
- Where
- United States
- Volunteers
- 2,430 people
- Sponsor
- Helen Foundation
Psoriasis
Pythagorean Self-Awareness Intervention on Psoriasis Patients.
This one-arm, pilot, non-randomized, study was conducted at the Specialized Psoriasis Unit of Andreas Syggros Hospital in Athens, Greece.
- Trial name
- PSAIPSORIASI (NCT06691763)
- Testing
- Pythagorean Self-Awareness Intervention for stress management and health promotion
- Where
- Greece
- Volunteers
- 21 people
- Sponsor
- National and Kapodistrian University of Athens
Heart Arrest
Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest
A randomized controlled trial did not show benefit of vasopressin versus epinephrine in inhospital cardiac arrest. Preceding laboratory data suggest that combined vasopressin and epinephrine ensure long-term survival and…
- Trial name
- NCT00411879
- Testing
- Vasopressin, Epinephrine, and Steroids
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Athens
Post-Dural Puncture Headache
Pregabalin Versus Hydrocortisone for Postdural Puncture Headache After Spinal for Cesarean
Postdural puncture headache (PDPH) is a common complication after spinal anesthesia. The role of pregabalin and hydrocortisone in the treatment of PDPH is unclear.
- Trial name
- PDPH (NCT03910088)
- Testing
- Pregabalin 100Mg Oral Cap, Hydrocortisone, Acetaminophen
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Healthy
Glucose Metabolism and Quality of Life in Healthy Women
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women. Women with PCOS often have problems with fertility, unwanted hair growth, and irregular menstrual cycle.
- Trial name
- Healthywomen (NCT01995773)
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital