Clinical trials: Hydroxychloroquine
Pneumonitis, Interstitial, COVID-19
TOFAcitinib Plus Hydroxycloroquine vs Hydroxycloroquine in Patients With COVID-19 Interstitial Pneumonia
Multifocal interstitial pneumonia represents the most common cause of admission in intensive care units and death in SARS-CoV2 infections.
- Trial name
- TOFACoV-2 (NCT04390061)
- Testing
- Tofacitinib, Hydroxychloroquine
- Volunteers
- 116 people
- Sponsor
- Università Politecnica delle Marche
COVID-19
Safety and Efficacy of PHR 160 Spray on the Outcomes of Patients With COVID-19
This study is a multi-center randomized, controlled, and blinded clinical trial study that will be performed in four medical-educational centers.
- Trial name
- NCT04463420
- Testing
- PHR160 Spray, Standard treatment
- Where
- Iran
- Volunteers
- 224 people
- Sponsor
- Baqiyatallah Medical Sciences University
Cutaneous Lupus Erythematosus-Systemic Lupus Erythematosus
Multicenter Study Assessing the Efficacy & Safety of Hydroxychloroquine Sulfate in Patients With Systemic Lupus Erythematosus or Cutaneous Lupus Erythematosus With Active Lupus Erythematosus Specific Skin Lesion
Primary Objective: To investigate the efficacy on skin manifestation of 16 weeks treatment of once daily regimen of hydroxychloroquine sulphate (HCQ) in patients with cutaneous lupus erythematosus (CLE) and systemic lupus…
- Trial name
- NCT01551069
- Testing
- hydroxychloroquine (Z0188)
- Where
- 22 sites in Japan
- Volunteers
- 103 people
- Sponsor
- Sanofi
Graft Versus Host Disease
Hydroxychloroquine in Treating Patients With Newly Diagnosed Chronic Graft-Versus-Host Disease
RATIONALE: Hydroxychloroquine may decrease the immune response and be effective in treating chronic graft-versus-host disease. It is not yet known if standard therapy for graft-versus-host disease is more effective with or…
- Trial name
- NCT00031824
- Testing
- cyclosporine, hydroxychloroquine, prednisone
- Where
- 104 sites in United States, Australia and 4 more
- Volunteers
- 82 people
- Sponsor
- Children's Oncology Group
Solid Tumor, Advanced Breast Cancer
Hydroxychloroquine, Abemaciclib and Endocrine Therapy in Hormone Receptor Positive (HR+)/Her 2 Negative Breast Cancer
The hypothesis is that abemaciclib synergizes with autophagy inhibitor hydroxychloroquine (HCQ/ Plaquenil), inducing apoptosis leading to tumor regression.
- Trial name
- NCT04316169
- Testing
- Abemaciclib, Hydroxychloroquine 200 mg, Faslodex
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Chronic Urticaria
Hydroxychloroquine Efficacy in Chronic Urticaria
This study is for those people with difficult to treat hives. We are investigating whether or not a different medication, hydroxychloroquine, works to treat a certain type of hives.
- Trial name
- NCT01073852
- Testing
- Hydroxychloroquine
- Sponsor
- Vanderbilt University
Non-Small Cell Lung Cancer, KRAS Mutation-Related Tumors
Binimetinib and Hydroxychloroquine in Patients With Advanced KRAS Mutant Non-Small Cell Lung Cancer
This study will evaluate using hydroxychloroquine (HCQ) along with binimetinib as an effective method for treating cancer. All patients will receive binimetinib at a standard dose approved for other cancers.
- Trial name
- NCT04735068
- Testing
- Binimetinib Pill, Hydroxychloroquine Pill
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
COVID-19, Severe Acute Respiratory Syndrome
Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients (PHYDRA Trial)
Triple blinded, phase III randomized controlled trial with parallel groups (200mg of hydroxychloroquine per day vs. placebo) aiming to prove hydroxychloroquine's security and efficacy as prophylaxis treatment for healthcare…
- Trial name
- PHYDRA (NCT04318015)
- Testing
- Hydroxychloroquine
- Where
- Mexico
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- National Institute of Respiratory Diseases, Mexico
Preeclampsia
The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for Preeclampsia
This study is prospective, single arm group ,open label, and multicenter trial (with two parallel-group [Hydroxychloroquine 200mg with Aspirin 100mg or Aspirin 100mg])
- Trial name
- HUGS (NCT05287321)
- Testing
- Hydroxychloroquine
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yoo-min Kim
Covid19, COVID-19 Prevention
Hydroxychloroquine (HCQ) as Post Exposure Prophylaxis (PEP) for Prevention of COVID-19
COVID-19 affected more than 9 million of people with more than 130 thousand death in India. If adequate preventive and therapeutic measures are not taken, India has very high risk of affecting million of more people with high…
- Trial name
- PEP-CQ (NCT04858633)
- Testing
- Hydroxychloroquine (HCQ), Standard care
- Where
- India
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh