Clinical trials: Ibuprofen, completed
Acute Sore Throat Pain
Ibuprofen Lozenge in Acute Sore Throat Pain
The purpose of this study is to evaluate the efficacy and safety of repeated doses of a low dosage of oromucosal Ibuprofen form (lozenge) versus placebo in patients suffering from acute sore throat pain.
- Trial name
- NCT01785862
- Testing
- Ibuprofen 25 mg
- Where
- 14 sites in France, Germany and 2 more
- Volunteers
- 427 people
- Sponsor
- Pierre Fabre Medicament
Rotator Cuff Tear
A Selective COX-2 Inhibitor Provides Pain Control But Hinders Healing Following Arthroscopic Rotator Cuff Repair
Selective cyclooxygenase (COX)-2 inhibitors are commonly used analgesics that provide similar analgesia but reduced adverse effects compared to other analgesics.
- Trial name
- NCT02850211
- Testing
- Celecoxib, Ibuprofen, Tramadol
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Healthy
Bioequivalence Study of Ibuprofen 200 mg/5 mL Oral Suspension vs. MOMENT 200 mg Coated Tablet
The main objective of the study is to evaluate the bioequivalence of a new formulation of ibuprofen 200 mg/5 mL oral suspension vs.
- Trial name
- NCT02902289
- Testing
- Ibuprofen 200 mg/5 mL oral suspension, MOMENT 200 mg coated tablet
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Postoperative Pain, Myalgia
Effects of Preemptive Paracetamol and Ibuprofen on Headache and Myalgia in Patients After Electroconvulsive Therapy
The primary aim this prospective, randomized, double-blind, placebo-controlled clinical trial is to compare the analgesic effects of preemptive intravenous paracetamol and ibuprofen on headache and myalgia, and secondary aim is…
- Conditions
- Postoperative Pain, Myalgia, Headache
- Trial name
- ECT (NCT03783312)
- Testing
- paracetamol, ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Inonu University
Contraception
The Effect of Ibuprofen on Intrauterine Contraceptive Device Associated Uterine Bleeding
The Copper intrauterine device is the most common method of reversible contraception worldwide. Abnormal uterine bleeding and pain are the most common medical indications for the discontinuation of the intrauterine device.
- Trial name
- NCT02580344
- Testing
- Ibuprofen
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Assiut University
Pelvic Pain
Efficacy of the Photobiomodulation on the Pelvi-perineal Pain in Immediate Post-partum Situation
Photobiomodulation (PBM), evaluated in this study, will be delivered by a CE marked class IIa medical device (MILTA technology), composed of a panel that gathers 18 emitters.
- Trial name
- NCT04896034
- Testing
- MILTA Device, " control 1 " fake MILTA device
- Where
- France
- Volunteers
- 480 people
- Sponsor
- Elsan
Postoperative Pain Management
Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery
Primary aim of this prospective, randomized, double-blind, placebo-controlled clinical trial is to compare the analgesic effects of IV ibuprofen and paracetamol on postoperative pain, and secondary aim is the effects on morphine…
- Trial name
- ibuprofen (NCT03437707)
- Testing
- Morphine Sulfate, Intravenous paracetamol, Intravenous ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Inonu University
Analgesics Use During Breastfeeding and Concentrations in Human Mature Milk
Study of Analgesics Drug and Human Milk Transfer in Mature Milk, to Avoid Breastfeeding Cessation Without Scientific Probes
The purpose of this study is to determine whether ibuprofen and ketoprofen do not enter into mature breastmilk that could allowed breastfeeding during a long time
- Trial name
- ANTALAIT (NCT01854411)
- Testing
- analgesic measure
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cholecystitis, Cholecystitis, Acute
TAP Block vs External Oblique Plane Block for Laparoscopic Cholecystectomy Surgery
Ultrasound (US) guidedTransversus Abdominis Plane Block (TAPB) is performed by injecting a local anesthetic into the plane between the internal oblique and transverse abdominis muscles and provides analgesia in the anterolateral…
- Conditions
- Cholecystitis, Cholecystitis, Acute, Cholecystitis, Chronic
- Trial name
- NCT06178757
- Testing
- TAPB, EOIB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Orthodontic Pain
Acetaminophen Versus Ibuprofen for the Control of Immediate and Delayed Pain Following Orthodontic Separator Placement
The purpose of this research study is to compare pain control effectiveness of two medicines and a placebo (a dummy pill that does not contain any pain relieving medication) to see which one works better at preventing pain when…
- Trial name
- NCT00484744
- Testing
- Acetaminophen, Ibuprofen
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Breast Pain
Premedication to Reduce Discomfort With Screening Mammography
This study will explore the effect of pre-medication with acetaminophen, ibuprofen, and topical lidocaine gel (Topicaine) on the perception of discomfort and overall satisfaction with the mammography experience.
- Trial name
- NCT00382083
- Testing
- 1000 mg acetaminophen, 800 mg ibuprofen, 1 oz 4% lidocaine gel
- Where
- United States
- Sponsor
- Mountain States Tumor and Medical Research Institute
Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women
xercise-induced muscle damage (EIMD) is a common consequence of unaccustomed or high-intensity exercise and is characterized by muscle soreness, impaired physical performance, inflammation, oxidative stress, and increased…
- Conditions
- Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS), Sports Recovery, Exercise-Induced Oxidative Stress
- Trial name
- CURACTIVE (NCT07785986)
- Testing
- Curcumin, Ibuprofen
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Postoperative Dental Pain
A Study to Asses the Effect of MK0663 in the Treatment of Patients With Postoperative Dental Pain (0663-092)
The purpose of this study is to compare the pain relieving effect of different doses of MK0663 with placebo and other pain relievers/analgesics in patients with postoperative dental pain.
- Trial name
- NCT00694369
- Testing
- Comparator: etoricoxib, Comparator: ibuprofen, Comparator: acetaminophen + codeine
- Volunteers
- 588 people
- Sponsor
- Organon and Co
Fever
Safety, Efficacy, and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients
The primary objective of the study is to determine the superiority of a single dose of intravenous ibuprofen compared to acetaminophen for the treatment of fever during the first two hours of treatment.
- Trial name
- NCT01002573
- Testing
- ibuprofen, acetaminophen
- Where
- 17 sites in United States
- Volunteers
- 118 people
- Sponsor
- Cumberland Pharmaceuticals
Osteoarthritis, Hypertension
To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension
To assess the effect of naproxcinod vs. naproxen and ibuprofen on arterial blood pressure in patients with osteoarthritis and controlled essential hypertension
- Trial name
- HCT3012-X-112 (NCT00662896)
- Testing
- naproxcinod 375 mg bid, naproxcinod 750 mg bid, naproxen 250 mg bid
- Where
- 57 sites in United States
- Volunteers
- 300 people
- Sponsor
- NicOx
Other Chronic Postoperative Pain
High Pain Intervention in Cesarean Sections
In previous studies the investigators have seen that the severity of pain one day after cesarean delivery can predict the presence of pain and depression 2 months later.
- Trial name
- NCT01298778
- Testing
- Duramorph 150, Acetaminophen, Duramorph 300
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Wake Forest University Health Sciences
Knee Osteoarthritis
NSAID Treatment in Knee Osteoarthritis
Central mechanisms may play a role in pain perception during osteoarthritis (OA).Local inflammation (which involves production of pro-inflammatory cytokines such as interleukin (IL) 4 TNF-alpha, IL-6 and IL-8) is considered to be…
- Trial name
- NSKO (NCT01860833)
- Testing
- Ibuprofen, Celecoxib, Diclofenac
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- University of Catanzaro
Back Pain, Neck Pain
Ibuprofen/Caffeine Lower Back or Neck Pain Study
To assess the efficacy and safety of a 400 mg ibuprofen/100 mg caffeine tablet in comparison to a 400 mg ibuprofen tablet for the treatment of acute lower back or neck pain.
- Trial name
- NCT03003000
- Testing
- ibuprofen, caffeine
- Where
- 18 sites in Germany, Russia
- Volunteers
- 635 people
- Sponsor
- Boehringer Ingelheim
Osteoarthritis, Hip, Arthroplasty, Replacement, Hip
Prevention of Ectopic Bone Related Pain and Disability After Hip Replacement Surgery With Peri-Operative Ibuprofen
The primary aim of this randomised trial is to determine the effects of a short peri-operative course of treatment with a non-steroidal anti-inflammatory drug (NSAID), ibuprofen, on the long-term consequences of ectopic bone…
- Conditions
- Osteoarthritis, Hip, Arthroplasty, Replacement, Hip, Arthritis, Rheumatoid
- Trial name
- NCT00145730
- Testing
- Ibuprofen
- Volunteers
- 1,000 people
- Sponsor
- The George Institute
Lower Extremity Amputation
Adherence and Perspiration While Wearing Lower Limb Prostheses
Individuals with lower limb amputation often complain about uncomfortable residual limb skin temperatures and the accumulation of sweat inside their prostheses.
- Trial name
- NCT03900845
- Testing
- Dynamic Air Exchange - Rising Edge Design (DAE-RED), Perforated elastomeric liner, As-prescribed prosthesis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research