Clinical trials: Ibuprofen, completed
Pre-Eclampsia, HELLP Syndrome
Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features
NSAIDs, specifically cyclo-oxygenase (COX) inhibitors, are known to increase blood pressure over time in non-pregnant adults, but the effect of COX-inhibitors on blood pressure in the setting of preeclampsia have not been well…
- Conditions
- Pre-Eclampsia, HELLP Syndrome, Eclampsia
- Trial name
- NCT02911701
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Analgesia
Effect of Paracetamol and Ibuprofen Reducing Morphine Requirements After Total Knee Arthroplasty
Adequate pain management has an important role in supporting early ambulation after the Total Knee Arthroplasty (TKA). Multimodal analgesia is one of the modalities of overcoming postoperative pain.
- Trial name
- PctIbfFKUI (NCT04414995)
- Testing
- Paracetamol injection and Ibuprofen injection, Paracetamol injection and normal saline, Ibuprofen Injection and normal saline
- Where
- 2 sites in Indonesia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Fever, Respiratory Tract Infection
The Efficacy and Safety of Dexibuprofen Syrup
The purpose of this study is to compare the safety and efficacy of dexibuprofen syrup and ibuprofen syrup in patients with fever due to common cold.
- Trial name
- NCT00812422
- Testing
- Dexibuprofen, Ibuprofen
- Where
- 4 sites in South Korea
- Volunteers
- 260 people
- Sponsor
- Inje University
Post Operative Dental Pain
A Study to Assess the Efficacy and Tolerability of Diclofenac Potassium Soft Gelatin Capsules Compared With Ibuprofen Tablets in Patients With Moderate to Severe Postoperative Dental Pain
The study is designed to assess the efficacy and tolerability of diclofenac potassium soft gelatin capsules compared with ibuprofen tablets in patients with moderate to severe postoperative dental pain.
- Trial name
- NCT02476422
- Testing
- Diclofenac potassium, Ibuprofen
- Where
- United States
- Volunteers
- 328 people
- Sponsor
- Novartis Pharmaceuticals
Post-operative Dental Pain
Randomized, Double-Blind, Single-Dose, Efficacy and Safety Study of Test Acetaminophen Tablet in Postoperative Dental Pain
To evaluate analgesic onset, efficacy, and safety of 1000 mg acetaminophen administered as two Test Acetaminophen 500 mg tablets (Test ACM) compared with 1000 mg acetaminophen administered as two commercial acetaminophen 500 mg…
- Trial name
- NCT03224403
- Testing
- Test acetaminophen, Commercial acetaminophen, Commercial ibuprofen
- Where
- United States
- Volunteers
- 664 people
- Sponsor
- Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division
Osteoarthritis, Pain
Evaluation of the Effectiveness, Compliance of Ibuprofen in a Sustained Release Form in the Treatment of Egyptian Osteoarthritic Patients
This is a prospective, multi-center, post-marketing observational study to evaluate the effectiveness and compliance of ibuprofen in a sustained release form in the treatment of Egyptian osteoarthritic patients.
- Conditions
- Osteoarthritis, Pain, Morning Stiffness
- Trial name
- NCT01226095
- Where
- 15 sites in Egypt
- Volunteers
- 519 people
- Sponsor
- Abbott
Pneumococcal Vaccines
Study Assessing the Effect of Medications to Prevent Fever on Prevenar 13®
The purposes of this study are assess the immunological response (measure the amount of antibodies, i.e. proteins that fight off germs) produced by children after they have been given the 13-valent pneumococcal vaccine (13vPnC)…
- Trial name
- NCT01392378
- Testing
- 13-valent pneumococcal conjugate vaccine, INFANRIX hexa, Paracetamol
- Where
- 14 sites in Poland
- Volunteers
- 908 people, healthy volunteers welcome
- Sponsor
- Pfizer
NSAID, Pain Management
Pre-emptive Analgesics in Orthodontic Treatment
This study is designed to determine if the preemptive use of a combination of acetaminophen and ibuprofen is more effective in reducing pain following orthodontic tooth movement when compared to the use of acetaminophen and…
- Trial name
- NCT03523988
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Washington
Postoperative Pain
Effect of Root Canal Treatment (Versus no Treatment) for Patients With Tooth Infections and Toothaches
The purpose of this study is to evaluate patients with emergency pain and a sore (infected) tooth to determine if immediate root canal therapy is better at reducing pain, when compared to initial treatment with antibiotic and…
- Trial name
- NCT01870973
- Testing
- root canal treatment, anesthesia, pain medications, and antibiotic, no root canal treatment, anesthesia, pain medications, and antibiotic
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Ohio State University
Carpal Tunnel Syndrome, Ibuprofen
Ibuprofen and Neural Mobilization Treatment in Carpal Tunnel Syndrome.
In the present investigation, the pain reduction effect of median nerve neural mobilization and oral ibuprofen treatments will be compared to those produced by the absence of treatment, in subjects who suffer the signs and…
- Conditions
- Carpal Tunnel Syndrome, Ibuprofen, Pain Management, Pain, Chronic
- Trial name
- NCT04328805
- Testing
- ibuprofen tablets, Median nerve neural mobilization
- Where
- Venezuela
- Volunteers
- 123 people
- Sponsor
- Universidad Europea de Madrid
Idiopathic Intracranial Hypertension
Idiopathic Intracranial Hypertension Treatment Trial
Idiopathic intracranial hypertension (IIH), also called pseudotumor cerebri, is a disorder of elevated intracranial pressure of unknown cause [Corbett, et al., 1982; Wall, et al., 1991].
- Trial name
- IIHTT (NCT01003639)
- Testing
- Acetazolamide, Formal weight loss counselling program
- Where
- 41 sites in United States, Canada
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Acute Pain, Analgesics
Monitoring Side Effects Of Pain Medication Prescribing By Emergency Department In Patients Over 65
Half of the people over the age of 65 are not functioning at their optimal level because of interference from pain. > 50% of older adults had taken prescriptions of pain medication beyond a 6-month period.
- Conditions
- Acute Pain, Analgesics, Elderly
- Trial name
- MOSE65 (NCT02046681)
- Where
- 5 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
IUD Removal
Use of Ibuprofen to Prevent IUD Site Effects
This research will determine whether prophylactic use of ibuprofen can prevent common side effects of the copper intrauterine device (IUD) and prevent early removal of the device.
- Trial name
- NCT00243815
- Testing
- ibuprofen
- Where
- Chile
- Volunteers
- 2,019 people, healthy volunteers welcome
- Sponsor
- FHI 360
Osteoarthritis of the Hip or Knee
Dexibuprofen 400 mg Sachet Versus Ibuprofen 400 mg Sachet in Patients With Osteoarthritis of the Hip or Knee
Medical condition under investigation: Osteoarthritis of the hip or knee Number of patients planned: 480 adult patients Main objective: To evaluate and compare the tolerability profile of Dexibuprofen Gebro 400 mg powder for oral…
- Trial name
- NCT01066676
- Testing
- Dexibuprofen, Ibuprofen
- Where
- 2 sites in Austria
- Volunteers
- 482 people
- Sponsor
- Gebro Pharma GmbH
Patent Ductus Arteriosus
Treatment of a PDA With Acetaminophen in Preterm Neonates: Exploring Various Indications
This study will evaluate the use of acetaminophen in preterm infants when a patent ductus arteriosus (PDA) is of concern. We will perform two simultaneous prospective observational studies over a 3 year period.
- Trial name
- NCT03289390
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Albany Medical College
Osteoarthritis
An Investigational Drug in Patients With Osteoarthritis (0663-073)
This study was conducted to assess the safety and tolerability of an investigational drug and to evaluate its effectiveness in the treatment of osteoarthritis of the hip or knee in both men and women.
- Trial name
- NCT00092755
- Testing
- MK0663, etoricoxib
- Volunteers
- 548 people
- Sponsor
- Organon and Co
Gonarthrosis; Primary
The Effect of Different Intra-articular Injections Primary Gonarthrosis
Gonarthrosis is a frequent cause of knee pain and mostly related to altered function of the knee. Intra-articular injections are a valuable noninvasive medical treatment of choice for pain management and functional enhancement.
- Trial name
- NCT05291793
- Testing
- Tenoxicam 20 Mg Powder for Solution for Injection Vial, Methylprednisolone, Saline
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nevsehir Haci Bektas Veli University
Skeletal Muscle Mass Regulation
The Effects of COX-inhibiting Drugs on Skeletal Muscle Adaptations to Resistance Exercise in Healthy Adults
In this study, healthy human subjects (18-35 yrs) are be randomised to consume 1200 mg ibuprofen or 75 mg acetylsalicylic acid daily during a training period of 8 weeks.
- Trial name
- NSAID2015 (NCT02531451)
- Testing
- Ibuprofen, Acetylsalicylic acid
- Where
- Sweden
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pain, Acute
Adult Oral Ibuprofen Study for ED Pain Patients
Ibuprofen is one of the most widely used non-steroidal anti-inflammatory drug (NSAID) for management of mild -to moderate pain in the ED (acute musculo-skeletal pain, headache, dental pain).
- Trial name
- NCT03441269
- Testing
- Oral Ibuprofen
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Antonios Likourezos
Failure of Dental Implant Due to Lack of Attached Gingiva
Gingival Augmentation Around Implants During Maintenance
This prospective controlled randomized blind clinical study investigated 44 implants displaying lack of KG in 29 subjects. Fourteen subjects received FGGs followed by oral prophylaxis.
- Trial name
- NCT02904551
- Testing
- Free gingival graft, Oral prophylaxis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore