Clinical trials: Ibuprofen, completed
Prostate Cancer
Evaluation of Safety and Feasibility of OGX-011 in Combination With 2nd-line Chemotherapy in Patients With HRPC
This study is for patients with cancer of the prostate gland that has metastasized or spread outside the prostate to other parts of the body.
- Trial name
- NCT00327340
- Testing
- custirsen (OGX-011)/mitoxantrone, custirsen (OGX-011)/docetaxel
- Where
- 10 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Achieve Life Sciences
Heat, Pain
Use of ThermaCare Heat Wraps and Ibuprofen as an Adjunct to Physical Therapy for Neck Pain
Objective- To see if the use of heat at home between physical therapy sessions results in better therapy outcomes in people with acute neck pain.
- Trial name
- NCT02327338
- Testing
- thermacare heat wraps, Ibuprofen
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Future Sciene Technology
Appetitive Behavior, Pediatric Obesity
IL-6 in Exercise-Induced Anorexia
This study investigates the effect of high intensity exercise, with and without the inflammation inhibitor, ibuprofen, on plasma levels of IL-6 and other selective biomarkers of inflammation and appetite on food intake and…
- Trial name
- NCT03295968
- Testing
- High Intensity Exercise/Ibuprofen
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Volunteer Study
Ibuprofen Suspension Bioequivalence Study
The purpose of this study was to determine the rate and extent of absorption of Ibuprofen suspension formulations.
- Trial name
- NCT02503085
- Testing
- Nurofen for Children®, Algifor Dolo Junior®
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Osteoarthritis, Knee
Efficacy and Safety of Celecoxib Versus Placebo in the Treatment of Patients With Osteoarthritis of the Knee Who Were Unresponsive to Naproxen and Ibuprofen
To compare the safety and efficacy of celecoxib versus placebo in the treatment of patients with knee osteoarthritis who were unresponsive to treatment with prescription strength naproxen and ibuprofen or who could not tolerate…
- Trial name
- NCT00640627
- Testing
- Celecoxib
- Where
- 30 sites in United States
- Volunteers
- 380 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Alzheimer's Disease
Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease
This is a global Phase III, randomized, double-blinded, placebo-controlled study for subjects with evidence of early AD. The protocol is designed to determine whether ALZT-OP1 combination treatment (ALZT-OP1a + ALZT-OP1b) will…
- Trial name
- COGNITE (NCT02547818)
- Testing
- ALZT-OP1a, ALZT-OP1b
- Where
- 121 sites in United States, Australia and 5 more
- Volunteers
- 620 people
- Sponsor
- AZTherapies, Inc.
Low Back Pain
Ibuprofen Plus Metaxolone, Tizanidine, or Baclofen for Low Back Pain
This is a randomized study, based in emergency departments, in which the investigators determine the utility of adding various skeletal muscle relaxants to standard therapy, which consists of ibuprofen and an educational session.
- Trial name
- NCT03068897
- Testing
- Metaxalone, Tizanidine, Baclofen
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Montefiore Medical Center
Osteoarthritis, Rheumatoid Arthritis
Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment
The purpose of this study is to evaluate the safety of long-term treatment with HZT-501, a fixed-dose combination oral tablet of 800 mg ibuprofen and 26.6 mg famotidine for patients that require long-term NSAID treatment.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome
- Trial name
- NCT00984815
- Testing
- HZT-501
- Where
- 4 sites in United States
- Volunteers
- 86 people
- Sponsor
- Amgen
Patent Ductus Arteriosus
Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants
Pharmacological closure of ductus arteriosus with prostaglandin (PG) inhibitors has been used for years. Previous studies indicated that ibuprofen has similar effect on ductal closure as indomethacin but has less adverse effects…
- Trial name
- NCT01758913
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Taipei Medical University Hospital
Oral Lichen Planus, Oral Lichenoid Mucositis
Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions.
Oral lichen planus (OLP) is a common chronic autoimmune disease associated with cell-mediated immunological dysfunction. Symptomatic OLP is painful and complete healing is rare.
- Conditions
- Oral Lichen Planus, Oral Lichenoid Mucositis, Oral Lichenoid Reaction
- Trial name
- NCT03509675
- Testing
- Ibuprofen suspension 5mg/100ml
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Washington
Breast Diseases
Serratus Posterior Superior Interfascial Plane Block for Breast Surgery
Regional techniques can be used for postoperative pain control following breast surgery. Ultrasound (US) guided serratus posterior superior block (SPSPB) is a new interfacial plane block defined by Tulgar et al in 2023.
- Trial name
- NCT05972083
- Testing
- Analgesia management; group S and C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Tooth Loss
Long- Term Follow-up of Extraction Socket Management
Twenty-nine patients needing single tooth replacement in aesthetic area were treated by extraction and socket preservation with saddle connective tissue graft between September 2009 and February 2012.
- Trial name
- NCT03410251
- Testing
- Socket preservation
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Liege
Patent Ductus Arteriosus
Efficacy and Safety of Oral Versus Intravenous Ibuprofen for PDA Treatment in ELBW Infants
To determine whether oral or intravenous ibuprofen has a better or same efficacy and tolerance in closure of patent ductus arteriosis in extremely-low-birth-weight preterm infants.
- Trial name
- NCT01261117
- Testing
- oral ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Postoperative Analgesia, Laparoscopic Hysterectomy
Preemptive Analgesia in Laparoscopic Hysterectomy
The aim of this study is to evaluate the effects of ibuprofen and paracetamol administered for pre-emptive analgesia to patients undergoing laparoscopic hysterectomy on pain scores during the first 24 hours postoperatively, the…
- Trial name
- NCT07401927
- Testing
- Ibuprofen, Parasetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Giresun University
Low Back Pain, Mechanical
Paracetamol, Dexketoprofen and Ibuprofen In Non-Traumatic Acute Low Back Pain
Currently, paracetamol and nonsteroidal antiinflammatory drugs are widely used by emergency physicians in Turkey for the treatment of patients with Non-Traumatic Acute Low Back Pain The objective of the study is compare the…
- Trial name
- NCT04609254
- Testing
- Paracetamol, Dexketoprofen, Ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Pamukkale University
Lung Diseases
Erector Spinae Plane Block or Serratus Anterior Plane (SAP) Block Following Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours at…
- Trial name
- NCT03960762
- Testing
- ESP block (Group ESP), SAP block (Group SAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Fever
Safety, Efficacy, and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients
The primary objective of the study is to determine the superiority of a single dose of intravenous ibuprofen compared to acetaminophen for the treatment of fever during the first two hours of treatment.
- Trial name
- NCT01002573
- Testing
- ibuprofen, acetaminophen
- Where
- 17 sites in United States
- Volunteers
- 118 people
- Sponsor
- Cumberland Pharmaceuticals
Primary Dysmenorrhea (PD)
Efficacy of Thread - Embedding Acupuncture for the Treatment of Primary Dysmenorrhea
The goal of this clinical trial is to learn whether thread-embedding acupuncture can help lower menstrual pain in women aged 18 to 29 years with primary dysmenorrhea.
- Trial name
- NCT07844174
- Testing
- Thread-Embedding Acupuncture, Heat Therapy, Ibuprofen 400Mg Tab
- Where
- Vietnam
- Volunteers
- 75 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Delayed Onset Muscle Soreness
Dosing Interval Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness
This is a Phase 2, prospective, randomized, dual-center, double-blind, placebo-controlled, parallel-group study designed to determine the dosing interval, efficacy and safety of SST-0225 (5.4 grams, applied up to 6 times in 24…
- Trial name
- DIS DOMS (NCT02339129)
- Testing
- SST-0225
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC
Perineal Injury, Perineal Pain
TECAR in the Management of Early Postpartum Perineal Pain.
The study aimed to evaluate the effect of TECAR (Capacitive and Resistive Energy Transfer) therapy on the level of pain and discomfort in the pelvic floor in women after an episiotomy or perineal tears, during the first two days…
- Conditions
- Perineal Injury, Perineal Pain, Vaginal Delivery, Instrumental Delivery
- Trial name
- NCT07730372
- Testing
- TECAR - Capacitive and Resistive Energy Transfer
- Where
- Poland
- Volunteers
- 182 people
- Sponsor
- Medical University of Gdansk