Clinical trials: Insulin, completed
Diabetes Mellitus, Type 2
A Research Study to Compare Two Types of Insulin, a New Insulin, Insulin Icodec and an Available Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Have Not Used Insulin Before (ONWARDS 3)
This study compares insulin icodec (a new insulin taken once a week) to insulin degludec (an insulin taken once daily which is already available on the market) in people with type 2 diabetes.
- Trial name
- ONWARDS 3 (NCT04795531)
- Testing
- Insulin icodec, Insulin degludec
- Where
- 190 sites in United States, Argentina and 10 more
- Volunteers
- 588 people
- Sponsor
- Novo Nordisk A/S
Polycystic Ovary, Obesity
Polycystic Ovary Syndrome and BETATROPHIN
This is an original study giving an information about the association body mass index, polycystic ovary syndrome and betatrophin.
- Trial name
- NCT04448730
- Testing
- serum marker levels
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Hatice Akkaya
COVID-19, Dysglycemia
Can Intensive Insulin Therapy Improve Outcomes of COVID-19 Patients
Evaluation of the reciprocal relation between hyperglycemia/diabetes mellitus (HG/DM) and COVID-19 disease and the effect of mode of insulin therapy; intensive (IIT) or conventional (CIT) on patients' outcomes All patients…
- Trial name
- NCT05441631
- Testing
- Insulin, Subcutaneous Insulin
- Where
- Egypt
- Volunteers
- 436 people
- Sponsor
- Benha University
Type 1 Diabetes Mellitus
At Home Study of a Zone-Model Predictive Control (MPC) Controller and a Health Monitoring System (HMS) With the Diabetes Assistant (DiAs) System and Run-to-Run Adaptation
This clinical trial is a study to assess the performance of an automated glucose control system (Artificial Pancreas, AP) device in home settings for subjects with type 1 diabetes.
- Trial name
- NCT02705053
- Testing
- CGM and Insulin Pump, Closed-Loop Control System
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Sansum Diabetes Research Institute
Diabetes Mellitus, Type 2
Ascertainment of EMR-based Clinical Covariates Among Patients Receiving Oral and Non-insulin Injected Hypoglycemic Therapy
The objective of this study is to identify EMR-based clinical covariates and quantify their association with the prescribing of each specific type 2 diabetes (T2DM) medication under investigation.
- Trial name
- NCT02140645
- Testing
- linagliptin
- Where
- United States
- Volunteers
- 166,613 people
- Sponsor
- Boehringer Ingelheim
Polycystic Ovary Syndrome, Obesity
Effects of Exercise for Overweight Women With Polycystic Ovary Syndrome
The effects of a 16-week exercise training program on insulin resistance and adiposity in overweight/obese women with Polycystic ovary syndrome (PCOS).
- Trial name
- POLY (NCT01150539)
- Testing
- 16-week exercise training program, Control Group without PCOS
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes
Evaluation of Correlations Between Volatile Organic Compounds and Venous Blood Glucose in Subjects With Type 2 Diabetes
The goal of this study is to evaluate correlations between VOCs in the breath and venous blood glucose values in various glycaemic states in people living with Type 2 Diabetes.
- Trial name
- Evo (NCT07147010)
- Testing
- MIB Breath Analyzer
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- DCB Research AG
Chronic Hepatitis B, Hepatic Fibrosis
Prospective Cohort Study of Association of Insulin Resistance/Steatosis With Hepatic Fibrosis in CHB and NAFLD
Hepatic steatosis and insulin resistance are associated with severity of fibrosis in non-alcoholic fatty liver disease (NAFLD) and chronic hepatitis C.
- Conditions
- Chronic Hepatitis B, Hepatic Fibrosis, Fatty Liver
- Trial name
- NCT02031913
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Boramae Hospital
Diabetes Mellitus, Type 1
A Study for Patients With Type 1 Diabetes Mellitus
The purpose of the study is to compare the human insulin inhalation powder plus insulin glargine with injected insulin (regular human insulin or insulin lispro) plus insulin glargine on lowering the blood sugar level.
- Trial name
- NCT00447213
- Testing
- Insulin glargine, Human Insulin Inhalation Powder, Injectable Insulin
- Where
- 5 sites in Japan, Taiwan
- Volunteers
- 70 people
- Sponsor
- Eli Lilly and Company
Type 1 Diabetes
Absorption of Insulin Following Subcutaneous Bolus Administration With Different Bolus Durations
To cover meal-related insulin requirements, insulin pumps allow insulin to be delivered at high rates over a short period of time (bolus delivery).
- Trial name
- NCT01792323
- Testing
- Insulin LISPRO
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Graz
Type 1 Diabetes
HCT Cash-Only INcentive to Promote Mealtime Insulin DOSE Engagement
Type 1 Diabetes (T1D) is a serious disease that happens because the body cannot control blood glucose (sugar) levels. People with T1D need insulin shots because their body does not make insulin. Insulin lowers blood sugar levels.
- Trial name
- NCT04621890
- Testing
- LOAN2DOSE and COIN2DOSE
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Children's Mercy Hospital Kansas City
Glucose Intolerance, Insulin Resistance
Iron and Insulin Resistance in Overweight and Obese Humans
Determine the effects of reducing whole-body iron stores in overweight/obese subjects (via one-time blood donation) on adipose tissue iron content, factors regulating iron homeostasis and lipolytic rate in adipose tissue, as well…
- Conditions
- Glucose Intolerance, Insulin Resistance, Iron Metabolism
- Trial name
- Fe (NCT03348020)
- Testing
- Blood Donation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Type 2 Diabetes Mellitus
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)
This study evaluated the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin.
- Trial name
- NCT04029480
- Testing
- Ertugliflozin 5 mg, Ertugliflozin 15 mg, Insulin
- Where
- 104 sites in United States, Belgium and 20 more
- Volunteers
- 166 people
- Sponsor
- Merck Sharp & Dohme LLC
Pediatric Obesity
Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity
This is a pilot study of children between the ages of 8 to 11 years of age who are obese and participating in an intense family based intervention with a family-focused multi-component lifestyle intervention.
- Trial name
- NCT02060279
- Testing
- Lifestyle intervention and carotenoid supplements
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Metabolic Syndrome, Dyslipidemia
Impact of Consumption of Beta-glucans on the Intestinal Microbiota and Glucose and Lipid Metabolism
The purpose of this study is to investigate if daily consumption of barley beta-glucans effect lipid and glucose metabolism and alter intestinal microbiota composition in participants with metabolic syndrome or with high risk for…
- Conditions
- Metabolic Syndrome, Dyslipidemia, Obesity, Abdominal, Hyperglycemia
- Trial name
- NCT02041104
- Testing
- Bread with added beta-glucans
- Where
- 3 sites in Slovenia
- Volunteers
- 51 people
- Sponsor
- Mlinotest Zivilska Industrija d.d.
Overweight, Healthy
Precision Exercise Therapeutics (PET-pilot)
The aim of this randomized cross-over study is to collect information for the design of a precision exercise therapy cohort that will predict what modality of physical activity a physically inactive individual with overweight…
- Trial name
- NCT05718089
- Testing
- Continuous aerobic exercise, High intensity interval training, Resistance training
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetes, Diabetes Mellitus, Type 2
Comparison of Pharmacodynamics and Pharmacokinetics of Biphasic Insulin Aspart 30 and Insulin Glargine and Insulin Glulisine Therapy in Subjects With Type 2 Diabetes
This trial is conducted in Europe. The aim of this clinical trial is to compare the 24-hour pharmacodynamics/ pharmacokinetics of biphasic insulin aspart 30 (BiAsp 30) thrice daily treatment with that of a basal-bolus treatment…
- Trial name
- NCT00824668
- Testing
- biphasic insulin aspart 30, insulin glargine, insulin glulisine
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Novo Nordisk A/S
Diabetes, Diabetes Mellitus, Type 1
Efficacy and Safety of Insulin Aspart in Subjects With Type 1 or Type 2 Diabetes
This trial is conducted in Asia. The aim of this trial is to compare the efficacy of postprandial plasma glucose of two treatment regimens in Chinese subjects.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00593255
- Testing
- soluble human insulin, insulin aspart, insulin NPH
- Where
- 5 sites in China
- Volunteers
- 220 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 1
Comparison of Insulin Degludec With Insulin Glargine U100 for Adults With Type 1 Diabetes Crossing Multiple Time Zones.
The purpose of the proposed study is to compare insulin Degludec [TRESIBA® (insulin degludec injection)] with insulin Glargine U100 [Lantus® (insulin glargine injection)] to determine the basal insulin of choice for adults with…
- Trial name
- SafrTravlT1D (NCT03668808)
- Testing
- Insulin Degludec, Insulin Glargine, TRESIBA® FLEXTOUCH®
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Sansum Diabetes Research Institute
Diabetes Mellitus, Type 1
INHALE-3: Afrezza® Combined With Insulin Degludec Versus Usual Care in Adults With Type 1 Diabetes
INHALE-3 is a Phase 4, randomized controlled trial (RCT) that will randomly assign participants ≥18 years of age with type 1 diabetes (T1D) using multiple daily injections (MDI), an automated insulin delivery (AID) system, or a…
- Trial name
- NCT05904743
- Testing
- Afrezza, insulin degludec, Rapid-acting Insulin Analog
- Where
- 19 sites in United States
- Volunteers
- 141 people
- Sponsor
- Mannkind Corporation
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.