Clinical trials: Insulin, completed
Healthy Volunteers
A Study of Lispro Formulations in Healthy Participants
The purposes of this study are to determine: Part A How quickly your body absorbs, breaks down and gets rid of the different formulations of insulin lispro compared to insulin lispro alone formulation.
- Trial name
- NCT02293551
- Testing
- Lispro
- Where
- Singapore
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Kidney Transplant; Complications
Effects of Empagliflozin in Reducing Oxidative Stress After Kidney Transplantation
The purpose of this study is to investigate the effect of empagliflozin on oxidative stress in patients with type 2 diabetes after kidney transplantation.
- Trial name
- NCT04918407
- Testing
- Empagliflozin 25 MG, Insulin
- Where
- 2 sites in Iran
- Volunteers
- 40 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Diabetes, Gestational
Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes
This clinical trial aims to test whether glibenclamide is non-inferior to insulin for the treatment of gestational diabetes.
- Trial name
- INDAO (NCT01731431)
- Testing
- Insulin, Glyburide
- Where
- France
- Volunteers
- 914 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Scalp Health, Hair Condition
Scalp Care Efficacy Evaluation for Premium Scalp Revitalizing Essence
The study aims to evaluate the efficacy of the Premium Scalp Revitalizing Essence on human scalp skin. A total of 60 healthy adults, aged 18 to 60, will be recruited and randomly assigned into five groups receiving different…
- Conditions
- Scalp Health, Hair Condition, Hair Loss, Sebum Production
- Trial name
- NCT06985121
- Testing
- Base formula only, Base formula plus IGF-1 and FGF-7, Base formula plus Centella asiatica extracellular vesicles
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Hypoglycemia
Glucagon Ready-to-Use (RTU) for Prevention of Exercise-Induced Hypoglycemia During Aerobic Exercise in Adults With T1D
This study is a randomized, placebo-controlled, double-blind, 2-treatment, 2-period, crossover comparison in a clinical research center (CRC) setting, followed by a randomized, placebo-controlled, double-blinded, 2-arm parallel…
- Trial name
- NCT03841526
- Testing
- Glucagon RTU Injection With Insulin Pump Reduction, Vehicle for Glucagon RTU Injection With Insulin Pump Reduction, Glugaon RTU Injection Without Insulin Pump Reduction
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Xeris Pharmaceuticals
Type 1 Diabetes
Multi-center Trial in Adult and Pediatric Patients With Type 1 Diabetes Using Hybrid Closed Loop System and Control at Home
The purpose of this study is to evaluate the safety and effectiveness of the Hybrid Closed Loop system (HCL) in adult and pediatric patients with type 1 diabetes in the home setting.
- Trial name
- NCT02748018
- Testing
- 670G and 770G Insulin Pump, Subject's Current Diabetes Therapy
- Where
- 36 sites in United States, Canada and 7 more
- Volunteers
- 959 people
- Sponsor
- Medtronic MiniMed, Inc.
Bariatric Surgery, Type 1 Diabetes
Hybrid Closed Loop Insulin Pump and Bariatric Surgery in Patients With Type 1 Diabetes
Bariatric surgery is increasingly performed on patients with type 1 diabetes. It exposes these patients to an increased risk of hypoglycemia, including severe hypoglycemia, and of severe episodes of hyperglycemia, beyond the…
- Trial name
- PompBariatDT1 (NCT06294704)
- Testing
- bariatric surgery
- Where
- 3 sites in France
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Sud Francilien
PCOS (Polycystic Ovary Syndrome), Insulinemic Response
The Effects Of Low Insulinemic Index Diet On Overweight And Obese Patients With Polycystic Ovary Syndrome
The aim of this study was to investigate the relationship between PCOS and insulinemic index in overweight and/or obese women with PCOS and to evaluate potential beneficial effects on PCOS.
- Trial name
- NCT07124767
- Testing
- 6 weeks of diet with low insulin index diet, 6 weeks of dieting according to TÜBER nutrition recommendations
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Betül Gümüş
Ischemic Stroke
Intensive Insulin Therapy With Tight Glycemic Control to Improve Outcomes After Endovascular Therapy for Acute Ischemic Stroke
The purpose of this study is to determine the safety and efficacy of lowering glucose (blood sugar), in addition to endovascular therapy, after acute ischemic stroke.
- Trial name
- NCT02054429
- Testing
- Insulin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University at Buffalo
Type 2 Diabetes, T2D
A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-1)
The main purpose of this study is to determine the efficacy and safety of insulin efsitora alfa (LY3209590) administered weekly using a fixed dose escalation compared to insulin glargine in adults with type 2 diabetes (T2D) who…
- Trial name
- QWINT-1 (NCT05662332)
- Testing
- Insulin Efsitora Alfa, Insulin Glargine
- Where
- 71 sites in United States, Argentina and 2 more
- Volunteers
- 795 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus
Inflammatory Response to CSII Catheters in a Tummy Tuck Model
In insulin pump therapy, insulin is continuously infused into the subcutaneous adipose tissue via a continuous subcutaneous insulin infusion (CSII) catheter using a basal/bolus pattern.
- Trial name
- IRCATT (NCT03298295)
- Testing
- Continous Subcutaneous Insulin Infusion Catheter
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Type 1 Diabetes
Impact of Introducing Basaglar Insulin to the Treatment Regimen of Youth With Diabetes in Pakistan
This study aimed to determine the effect of introducing Basaglar and insulin pen injection devices on clinical and quality of life (QOL) parameters in children and young adults with type 1 diabetes in Pakistan
- Trial name
- NCT06717191
- Testing
- biosimilar insulin glargine
- Where
- Pakistan
- Volunteers
- 296 people
- Sponsor
- Life for a Child Program, Diabetes Australia
Alzheimer's Disease, Mild Cognitive Impairment
Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart
This pilot clinical trial will examine the effects of intranasal insulin aspart on cognition, daily function, blood and cerebral spinal fluid markers of Alzheimer's disease, and amyloid deposition in the brain.
- Trial name
- SNIFF-Quick (NCT02462161)
- Testing
- Insulin aspart
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences
Diabete Type 2, Augmented Reality
Mobile Augmented Reality Learning On Insulin Administration Knowledge And Skills Of Patients
The goal of this study to determine the effectiveness of insulin administration with augmented reality on increasing the knowledge and skills of patients newly diagnosed with type 2 diabetes on insulin administrations…
- Conditions
- Diabete Type 2, Augmented Reality, Patient Education, Patient Education Materials
- Trial name
- NCT07087496
- Testing
- Insulin application training with mobile augmented reality, insulin administration training with brochure
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir Bakircay University
Type 1 Diabetes Mellitis
Evaluation of Insulin Glulisine (GP40321) Compared to Insulin Glulisine (Apidra® SoloStar®) in Type 1 Diabetes Mellitus Patients
The goal of this clinical trial is to demonstrate the non-inferior immunogenicity of GP40321 compared to Apidra® SoloStar® at a concentration of 100 U/mL in type 1 diabetes mellitus patients.
- Trial name
- NCT07070752
- Testing
- GP40321, Apidra® SoloStar®, RinGlar®
- Where
- 17 sites in Russia
- Volunteers
- 224 people
- Sponsor
- Geropharm
Diabetes Mellitus
THE Effect of Tight Glycemic Control on Microvascular Complications in Type 2 Diabetes Mellitus
The goal of this clinical trial is to learn the impact of tight versus less tight glycemic control on microvascular complications among Egyptian adults with uncontrolled T2DM.
- Trial name
- NCT07049601
- Testing
- Insulin Therapy, Antidiabetic therapy, lifestyle modification
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Gestational Diabetes Mellitus, Pregnancy in Diabetic
Patient Versus Provider-led Titration of Insulin for Glycemic Control in Gestational Diabetes (EMPOWER)
We propose a pragmatic, unblinded, randomized controlled, single center trial of 56 pregnant individuals with Gestational diabetes mellitus (GDM).
- Conditions
- Gestational Diabetes Mellitus, Pregnancy in Diabetic, Pregnancy, High Risk
- Trial name
- NCT05922033
- Testing
- Patient-led Insulin (intervention group), Provider-led Insulin (standard care)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ohio State University
Diabetes Mellitus, Type 2, Cardiovascular Diseases
A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease
The primary purpose of study is to estimate the incidence and comparative effect on health outcomes: 1) hospitalization for heart failure, 2) below knee lower extremity amputation.
- Trial name
- NCT03492580
- Testing
- Canagliflozin, Empagliflozin, Dapagliflozin
- Where
- United States
- Volunteers
- 714,582 people
- Sponsor
- Janssen Research & Development, LLC
Type 1 Diabetes, Diabetes
A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy
The main purpose of this study is to measure the safety and efficacy of insulin efsitora alfa (LY3209590) compared with insulin degludec in participants with type 1 diabetes treated with multiple daily injection therapy.
- Trial name
- QWINT-5 (NCT05463744)
- Testing
- Insulin Efsitora Alfa, Insulin Degludec
- Where
- 83 sites in United States, Argentina and 5 more
- Volunteers
- 692 people
- Sponsor
- Eli Lilly and Company
Type II Diabetes Mellitus, Gestational Diabetes Mellitus
Intrapartum Glycemic Control With Insulin Infusion Versus Rotating Fluids
This study will determine whether rotating intravenous (IV) fluid is better than receiving insulin to control a baby's blood sugar after delivery in laboring women with diabetes.
- Trial name
- NCT03912363
- Testing
- Rotating fluids protocol, Insulin infusion protocol
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic