Clinical trials: Intervention Group
Hemodialysis Complication
The Effect of Origami Activities on Comfort Level and Quality of Life
This study was conducted to evaluate the effect of origami activity on the comfort levels and quality of life of patients undergoing HD treatment.
- Trial name
- NCT07296757
- Testing
- origami
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kafkas University
COPD, Education
Efficacy of an Education Protocol in the Correction of Inhalation Techniques in COPD
This study evaluates the implementation of an education protocol and its impact on the correct inhalation technique in COPD patients presenting errors or mistakes.
- Trial name
- NCT03144557
- Testing
- Education
- Where
- Argentina
- Volunteers
- 61 people
- Sponsor
- Hospital Italiano de Buenos Aires
Opioid Use, Pain
Hip Arthroscopy Postoperative Opioid Demands
This study will be a prospective, single-blinded, randomized controlled trial (RCT), investigating the influence of the number of opioid pills prescribed following primary hip arthroscopy.
- Conditions
- Opioid Use, Pain, Femoral Acetabular Impingement, Labral Tear, Glenoid
- Trial name
- NCT04094701
- Testing
- Control Group Regimen, Opioid reduced regimen
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Breast Cancer Female, Quality of Life
Effects of Aerobic Exercise on Cancer-Related Biomarkers, Functional Capacity, Cognitive Status and Quality of Life in Women With Breast Cancer
This study aims to emphasize the exercise-induced changes in some circulating biomarkers (CRP, IGF-1(insulin like growth factor), insulin, leptin, IL-6(interleukin-6) , TNF-α(tumor necrosis factor), adiponectin), quality of life…
- Conditions
- Breast Cancer Female, Quality of Life, Survivorship
- Trial name
- NCT06540612
- Testing
- Aerobic exercise, Physical activity counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Hasan Kalyoncu University
Post Covid-19 Respiratory, Dyspnea
The Effects of a Music Therapy Respiratory Protocol on Post-Covid-19 Respiratory Symptoms
The effects of a tested and published music therapy respiratory protocol shown to be efficacious with pediatric asthma and adult COPD is being studied with individuals living with post-Covid-19 respiratory symptoms.
- Conditions
- Post Covid-19 Respiratory, Dyspnea, SARS-CoV 2
- Trial name
- NCT05231512
- Testing
- Respiratory Music Therapy Protocol
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hormone Receptor-Positive Breast Cancer, High-risk Breast Cancer
ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cancer
This is a Phase II, multicenter, randomized clinical trial evaluating a ctDNA-guided approach to de-escalate adjuvant chemotherapy in patients with hormone receptor (HR)-positive, HER2-negative early-stage breast cancer.
- Conditions
- Hormone Receptor-Positive Breast Cancer, High-risk Breast Cancer, Early-Stage Breast Cancer, HER2-negative Breast Cancer
- Trial name
- DNADalHR (NCT06970912)
- Testing
- Dalpiciclib + Aromatase Inhibitor with ctDNA-Guided Therapy, Taxane-Based Neoadjuvant Chemotherapy
- Where
- China
- Volunteers
- 393 people
- Sponsor
- Peking University People's Hospital
Physical Activity, Quality of Life
Improving Physical Activity in Young Adult Cancer Survivors
The Primary Goal is to conduct a 12 week pilot randomized controlled trial (RCT) of the Fitbit Flex, a popular, affordable, wearable physical activity tracking device, and the Fitbit mobile health (mHealth) app.
- Trial name
- NCT03233581
- Testing
- Fitbit + Facebook + Coaching Group, Fitbit only
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Substance Use Disorders
Strategies to Enhance Recruitment and Retention of Black Individuals Into Clinical Trials for Substance Use Disorders
The overall goal of this research project will be to obtain feedback from consumers to help develop a manual called I-DREM (Innovative Development of Research Engagement Manual).
- Trial name
- I-DREM (NCT05124119)
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Texas Southwestern Medical Center
Acute Coronary Syndrome, Procedural Complication
Decrease Artery Occlusion by Distal Radial Arterial Cannulation, Observational Study
The site of arterial access for coronary angiography and intervention has been the focus of research for decades as it is the source of major complications.
- Conditions
- Acute Coronary Syndrome, Procedural Complication, Outcome, Fatal
- Trial name
- DONATION-OB (NCT05230719)
- Testing
- Radial Artery Approach
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shenzhen People's Hospital
Neurofibromatosis Type 1
Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1
A physical training program will improve quality of life, participation in physical activity, motor coordination, muscle strength, and bone and muscle strength in children with neurofibromatosis type 1.
- Trial name
- NCT01058330
- Testing
- Plyometric training program
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Shriners Hospitals for Children
Anxiety Disorders, Social Anxiety Disorder
The Effectiveness of Transdiagnostic CBT Protocol on Anxiety Disorders
The transdiagnostic approach argues that the common features are needed to be taken into account [e.g. distress intolerance (DI), intolerance of uncertainty (IU), worry)] underlying emotional disorders rather than evaluating them…
- Conditions
- Anxiety Disorders, Social Anxiety Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT06422728
- Testing
- Unified Protocol for Anxiety Disorders, Client-centered Supportive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ibn Haldun University
Dementia, Stroke
Facilitating Caregiver Adaptation to Patient Institutionalization
This study will assess the effects of an intervention targeting family caregivers who recently placed a relative in a long-term care facility because of cognitive and/or physical disability.
- Conditions
- Dementia, Stroke, Heart Disease
- Trial name
- FACTS (NCT01194128)
- Testing
- Psychoeducational Support, Information only control group
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- University of Pittsburgh
Nicotine Dependence, Substance Use Disorders
Healthy People Initiative (HPI)
Addictions do not occur in isolation. Tackling addictions requires addressing social determinants such as isolation, homelessness, marginalization, and unemployment.
- Trial name
- HPI (NCT03506867)
- Testing
- Life skills, training, education and work/volunteer opportunities, Usual Care
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Healthy
Tuning in to Kids in School - Competence Building and Collaboration in the Team Around Primary School Students
The current project is a randomized controlled trial of the Australian evidence-based parenting program Tuning in to Kids® which has been adapted for using with Norwegian elementary school teachers (Tuning in to Kids in Schools…
- Trial name
- TIKiS (NCT06501300)
- Testing
- Emotion-focused: Tuning in to Kids in School
- Where
- Norway
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sophie Havighurst
Rhinitis, Allergic, Asthma
Study on the Correlation Between Intestinal Microecology and Allergic Diseases in Children
Allergic diseases, including allergic reactions of respiratory tract and skin, are often triggered by mast cell degranulation mediated by allergen-specific IgE and chronic inflammation of target organs, which are involved in a…
- Conditions
- Rhinitis, Allergic, Asthma, Dermatitis, Atopic, Urticaria
- Trial name
- NCT04938700
- Testing
- probiotics, conventional medical treatment
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Physical Therapy, Education
Bobath Instruction in Physiotherapy: Virtual Reality Versus Traditional Methods
This randomized controlled trial evaluated the effectiveness of immersive virtual reality (VR)-based instruction compared with traditional face-to-face teaching for delivering the Bobath concept in physiotherapy education.
- Conditions
- Physical Therapy, Education, Virtual Reality, Neurorehabilitation
- Trial name
- BOBATH-PT (NCT07270107)
- Testing
- Immersive VR headset instruction, Traditional instruction
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Musculoskeletal Diseases
Effects of Nurse-led Patient Pathways
Objectives: This quasi-experimental pre-post-study investigated the effect of newly developed Nurse-led Patient Pathways (NPP) designed to improve patients', and health care professionals' as well as institutional outcomes.
- Trial name
- NPP (NCT02543307)
- Testing
- Nurse-led Patient Pathways
- Where
- Switzerland
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Aortic Stenosis
Loss of Y Chromosome in Aortic Stenosis
The most common heart valve disease in humans is aortic stenosis which is a critical narrowing of the valve through which the heart has to pump blood to the rest of the body.
- Trial name
- NCT06595407
- Testing
- Blood analysis for loss-of-Y chromosome
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Spinal Deformity With Sagittal Imbalance
Surgical Treatment of Spinal Deformity With Sagittal Imbalance Using Patient-specific Rods: A Multicenter, Controlled, Double- Blind Randomized Trial: The PROFILE Study
Lumbar degenerative diseases (LDD) are an increasingly common condition affecting millions of patients worldwide. LDD can impact not only function, but can also become markedly disabling and cause severe chronic pain.
- Trial name
- PROFILE (NCT02730507)
- Testing
- Surgery with patient-specific rod, Conventional straight rod
- Volunteers
- 73 people
- Sponsor
- Hospices Civils de Lyon
Acute Myocardial Infarction
Effect of N-acetylcystein in Myocardial Infarction
We designed this study to evaluate the effect of N-acetylcystein on biomarkers of platelet activation , cardiac necrosis and coronary reperfusion in patients undergoing percutaneous coronary intervention.
- Trial name
- NCT01741207
- Testing
- N-acetylcystein
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Tehran University of Medical Sciences
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