Clinical trials: Intervention Group
Moderate to Severe Hypertension
Efficacy and Safety of the Combination of Aliskiren (300 mg) and Amlodipine (10 mg) Compared to Amlodipine (10 mg) Monotherapy in Patients With Moderate to Severe Hypertension
This study will compare the blood pressure (BP) lowering effect of the combination of aliskiren/amlodipine 300/10 mg versus amlodipine 10 mg monotherapy in patients with moderate to severe hypertension by testing the hypothesis…
- Trial name
- NCT00841672
- Testing
- Aliskiren/amlodipine 300/10 mg tablet, Amlodipine 10 mg capsule
- Where
- 6 sites in Germany, Philippines and 4 more
- Volunteers
- 485 people
- Sponsor
- Novartis
Lung Cancer
Evaluation of Computer-Aided Lung Nodule Detection Software in Thoracic CT for Riverain Technologies LLC
STUDY DESIGN: This is a retrospective, multi-reader, multi-case, (MRMC) randomized reader study. OBJECTIVE: Primary: The primary objective of this clinical study is to prove that a user aided with ClearRead CT InSight (CRCTI) is…
- Trial name
- NCT02440139
- Testing
- ClearRead CT Insight
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Virginia Polytechnic Institute and State University
Thyroid Papillary Carcinoma, Thyroidectomy
Comparison Between the Axillary Bilateral-breast Approach (ABBA) and Bilateral Axillo-breast Approach (BABA) for Robotic Thyroidectomy
The purpose of this study is to compare the therapeutic effects between the axillary bilateral-breast approach (ABBA) and bilateral axillo-breast approach (BABA) for robotic thyroidectomy.To explore the efficacy, safety, cosmetic…
- Trial name
- NCT02768753
- Testing
- The Axillary Bilateral-breast Approach, The bilateral Axillo-breast Approach
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jinan Military General Hospital
Disuse Osteoporosis
Zoledronic Acid Administration in Acute Spinal Cord Injury
In subjects with acute SCI: To compare the effects of parenteral zoledronic acid therapy on preservation of regional and total skeletal mass (DXA).
- Trial name
- NCT02042872
- Testing
- Zoledronic acid
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Arterial Hypertension, Hemodialysis
Mechanisms and Phenotypes of Hypertension in Patients in Chronic Hemodialysis
The goal of this study is to evaluate interdialytic blood pressure changes of the patients in chronic hemodialysis. The main question to be answered is: What is the relative importance of weight gain, the renin angiotensin…
- Trial name
- NCT06764277
- Testing
- There will be no intervention
- Where
- Mexico
- Volunteers
- 32 people
- Sponsor
- Bernardo Rodríguez Iturbe
Multiple Sclerosis
Physical Telerehabilitation in Veterans With Multiple Sclerosis
The primary objective of this study will be to assess the feasibility and patient acceptance of a Home Automated Telemanagement (HAT) system in multiple sclerosis patients.
- Trial name
- NCT02346734
- Testing
- Multiple Sclerosis Home Automated Telemanagement (MS HAT) system
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Maryland, Baltimore
Bariatric Surgery Candidate
Impact Of Post-Bariatric Body Contouring Procedures on Patient Body Weight and Metabolism
Is post-bariatric body contouring surgery prevent weight regain or no, and what is the effect on the patient's Metabolism? Few literature studies report body contouring surgery to be positively associated with maintained weight…
- Trial name
- NCT05034081
- Testing
- body contouring
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Heart Failure
Exercise Training in Heart Failure: Changes in Cardiac Structure and Function
This is a research study being conducted to better understand the impact of exercise training on changes on the structure and function of the heart.
- Trial name
- NCT02275819
- Testing
- Exercise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- VA Office of Research and Development
Weight Change, Body
Healthy Homes/Healthy Families (HH/HF) Intervention in 2-1-1 Callers
This trial will evaluate a healthy eating and weight gain prevention intervention for delivery through calls to the 2-1-1 number.
- Trial name
- NCT04373434
- Testing
- Health Homes/Healthy Families (HH/HF) Intervention, Control
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- Emory University
Arm Illness
The Effect of Questionnaire Content on Measures of Pain Intensity, Magnitude of Disability, and Symptoms of Depression in Patients With Arm Illness
The investigators plan a prospective randomized study to see whether negative questions affect measures of mood, pain, or disability. A total of 175 patients will participate at Massachusetts General Hospital.
- Trial name
- NCT02209259
- Testing
- PROMIS Upper Extremity Function, Pain intensity, PROMIS depression
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Massachusetts General Hospital
Cariostatic Agents, Mouthwashes
Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk
Dental caries is a localized, post eruptive pathological process involving softening of the hard tooth tissue and proceeding to the formation of cavity.
- Trial name
- AEXPC (NCT04399161)
- Testing
- Chlorhexidine mouthwash, Xylitol, Probiotic
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Dr. Krupa NC
Cutaneous Abscess
Evaluation of a Staphylococcus Eradication Protocol for Patients Who Present to the ED With Cutaneous Abscess
In this study, the investigators will enroll patients who present to the emergency department with abscesses to the study. The patients will be randomly selected to either have the standard of care, which includes the standard…
- Trial name
- NCT01537783
- Testing
- Chlorhexidine gluconate, Mupirocin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Tufts Medical Center
Prostate Cancer
Evaluation of Gallium-68-HBED-CC-PSMA Imaging in Prostate Cancer Patients
The investigators are imaging patients with prostate cancer using a new PET imaging agent (Ga-68 HBED-CC PSMA) in order to evaluate it's ability to detection prostate cancer in patients with high risk disease prior to…
- Trial name
- PSMA PET (NCT02611882)
- Testing
- Ga-68 labeled HBED-CC PSMA, Positron Emission Tomography (PET) image combined with Computed Tomography (CT) (PET/CT), Positron Emission Tomography (PET) image combined with Magnetic Resonance Imaging (MRI) (PET/MRI)
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Thomas Hope
Overactive Bladder
Over Active Bladder Patients Having Sling Surgery
The purpose of this study is to determine whether treatment with anti-muscarinic medications following sub-urethral sling procedures improves overall subjective and objective outcomes in women with mixed incontinence with primary…
- Trial name
- NCT00852696
- Testing
- Solifenacin
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Cleveland Clinic Florida
Pneumothorax
Bio-Seal Biopsy Track Plug for Reducing Pneumothorax Rates Post Lung Biopsy Procedure
BS-1053 A Prospective Randomized Multi-Centered Safety and Efficacy Evaluation of the Bio-Seal Biopsy Track Plug for Reducing Pneumothorax Rates Post Lung Biopsy Procedures
- Trial name
- NCT00562302
- Testing
- Bio-Seal Plug
- Where
- 18 sites in United States
- Volunteers
- 339 people
- Sponsor
- Angiotech Pharmaceuticals
Colorectal Cancer
The National CT Colonography Trial
RATIONALE: New diagnostic procedures such as computed tomographic colonography may improve the ability to detect colorectal cancer and may provide a less invasive method of detection.
- Trial name
- ACRIN6664 (NCT00084929)
- Testing
- CT Colonography
- Where
- 14 sites in United States
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- American College of Radiology Imaging Network
Infection, Human Immunodeficiency Virus, HIV Infections
Long-term Immunogenicity of the HIV gp120-NefTat/AS01B Vaccine (GSK SB732461)
The purpose of this study is to evaluate the long-term persistence of binding antibody responses against V1V2 and gp120 in subjects who were vaccinated with the envelope glycoprotein 120 (gp120)-negative factor (Nef)Tat/ Adjuvant…
- Trial name
- NCT03368053
- Testing
- Blood sampling
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
PreDiabetes, Prediabetic State
Implementation and Evaluation of a Diabetes Prevention Clinical Pathway in Primary Care
Prediabetes is a significant public health problem affecting 88 million U.S. adults. Evidence suggest that the vast majority of people with prediabetes are unaware of having this condition and many are not receiving appropriate…
- Trial name
- NCT05265312
- Testing
- START diabetes prevention clinical pathway
- Where
- United States
- Volunteers
- 1,910 people
- Sponsor
- Johns Hopkins University
Substance Use Disorders
Drum-Assisted Therapy for Native Americans
Drum-Assisted Recovery Therapy for Native Americans (DARTNA) is an R-21 NIH/NCCAM-funded study aimed to complete the development and pilot a new substance abuse treatment protocol utilizing drumming for American Indians/Alaska…
- Trial name
- NCT01356667
- Testing
- DARTNA, Treatment-As-Usual
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Dementia, Alzheimer Disease
Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers
The goal of this clinical trial is to evaluate Kinto's Care Coaching intervention for dementia caregivers. The main questions it aims to answer are: Does the intervention help caregivers to address their general caregiving goals…
- Conditions
- Dementia, Alzheimer Disease, Lewy Body Disease, Vascular Dementia
- Trial name
- NCT05916664
- Testing
- Kinto Care Coaching
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Kinto
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.