Clinical trials: Intervention Group
Lumbar Spinal Stenosis
Endoscopic Versus Conventional Lumbar Decompression for Lumbar Canal Stenosis
This is a randomized controlled trial comparing interlaminar uniportal endoscopic bilateral lumbar decompression with conventional open laminectomy in patients with degenerative lumbar canal stenosis.
- Trial name
- ENDOLSS (NCT07562035)
- Testing
- Interlaminar Uniportal Endoscopic Lumbar Decompression, Open Lumbar Laminectomy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Lung Cancer Non Small Cell
A Study of Lymph Node Metastatic Pattern Based Incorporating Tumor Location, GGO Components and Size for Non-small Cell Lung Cancer
The goal of this observational study is to learn about in invasive non-small cell lung cancer patients who underwent pulmonary resection with systematic lymph node dissection from April 2008 to July 2022 .
- Trial name
- NCT06161935
- Testing
- no intervention
- Volunteers
- 7,067 people
- Sponsor
- Fudan University
Ischemic Stroke, Acute, Sleep Disorders, Circadian Rhythm
The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Interventional)
There is a lack of complex studies which could establish the association between genetic circadian factors with the features and short-term outcomes of ischemic stroke, as well as the effects of various auxiliary therapies for…
- Trial name
- NCT05247125
- Testing
- Blue light exposure + Melatonin treatment, Melatonin treatment, Blue light exposure
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
COPD III/IV
The Effect of a Tidal Model-Based Approach Applied During Home Visits on Mental Health Parameters and Hospital Admission Frequency in COPD Patients
Despite the recent increased interest in identifying the needs of COPD patients and improving disease management, monitoring the psychosocial well-being of these individuals remains insufficient.
- Trial name
- Tidal Model (NCT06760325)
- Testing
- Tidal Model Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Kilis 7 Aralik University
Laparoscopic, Inguinal Hernia
Mesh Fixation Versus Non Fixation in Laparoscopic Inguinal Hernioplasty
Inguinal hernia is one of the most common types of abdominal hernias. Laparoscopic hernioplasty of inguinal hernia is a good alternative to traditional open repairs even in simple unilateral primary inguinal hernia in terms of…
- Conditions
- Laparoscopic, Inguinal Hernia, Hernioplasty
- Trial name
- NCT06258317
- Testing
- fixation of conventional polypropylene mesh
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Social Anxiety Disorder (SAD)
A Randomized, Controlled Study of Two At-Home Self-Guided Virtual Reality Interventions for Adults With Social Anxiety Disorder.
This study is to compare two Virtual Reality (VR)-based interventions, BVR-100 and BES-100, for the treatment of Social Anxiety Disorder (SAD).
- Trial name
- BVR-100-102 (NCT06037668)
- Testing
- BVR-100, BES-100
- Where
- 6 sites in United States
- Volunteers
- 56 people
- Sponsor
- Sumitomo Pharma America, Inc.
Autism, Dual Task
Single-Dual Task Performance in Children With Autism Spectrum Disorder and Typically Developing Children
This study aims to compare the effects of single-task and dual-task conditions on motor performance and postural control in children with Autism Spectrum Disorder (ASD) and typically developing children.
- Trial name
- NCT07323550
- Testing
- Single- and Dual-Task Condition Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Atlas University
Ureter Calculi
Stone Cone Device vs. Standard URS for Proximal Ureteral Calculi
Retrograde migration of stone fragments into the kidney during ureteroscopic lithotripsy (URS) for proximal ureteral stones is a common technical challenge, occurring in 5-40% of cases.
- Trial name
- NCT07769450
- Testing
- Ureteroscopic Pneumatic Lithotripsy with Cone Device, Standard Ureteroscopic Pneumatic Lithotripsy
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Provincial Headquarter Teaching Hospital Gilgit
Thrombocytopenia Associated With Chronic Liver Disease
A Study to Evaluate the Safety and Efficacy of PN20 in the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure
The main aim of this clinical trial is to assess the safety and efficacy of a single dose of PN20 in treatment of thrombocytopenia in adult patients with chronic liver disease undergoing an elective procedure.
- Trial name
- NCT07446491
- Testing
- PN20
- Where
- 8 sites in China
- Volunteers
- 54 people
- Sponsor
- Chongqing Peg-Bio Biopharm Co., Ltd.
Malignant Ascites
Treat Malignant Ascites Caused by Gastrointestinal or Ovarian Cancer With M701 Bispecific Antibody
A Phase II, Randomized, Open-label, Controlled, Multicenter Study to Evaluate the Efficacy and Safety of M701 in treating Patients with Malignant Ascites Caused by Gastrointestinal or Ovarian Cancer combined with Systemic Therapy.
- Trial name
- NCT06266091
- Testing
- M701, paracentesis
- Where
- China
- Volunteers
- 115 people
- Sponsor
- Wuhan YZY Biopharma Co., Ltd.
Obesity
Impact of Fitbit Plus Weight Management Program on Physical Activity and Metabolic Disease in Obese Adolescents
This study is evaluating the feasibility and efficacy of using Fitbit Charge HR devices to remotely track the physical activity of obese pediatric patients who are concurrently enrolled in a comprehensive weight loss intervention…
- Trial name
- NCT02507791
- Testing
- Fitbit Charge HR plus weekly phone calls to review physical activity data
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University Hospitals Cleveland Medical Center
Primary Immune Regulatory Disorder, Autoimmune Lymphoproliferative
A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition
The researchers are doing this study to find out whether emapalumab or a combination of fludarabine and dexamethasone are effective in preparing people with a primary immune regulatory disorder (PIRD) and/or an autoinflammatory…
- Conditions
- Primary Immune Regulatory Disorder, Autoimmune Lymphoproliferative, Immune System Diseases
- Trial name
- NCT05787574
- Testing
- Emapalumab, Fludarabine and Dexamethasone, Allogeneic hematopoietic stem cell transplant (allo-HCT)
- Where
- 13 sites in United States
- Volunteers
- 39 people
- Sponsor
- Joseph Oved
Pain
Pain Perception With Tenaculum Placement
Randomized controlled trial that compares methods of tenaculum placement during intrauterine device insertion and their effect on pain.
- Trial name
- NCT02969421
- Testing
- Cough method for placement of tenaculum, Slow Tenaculum Placement of tenaculum
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Duke University
Clinical Nursing Research
Effect of Cold Pressure in the Prevention of Hematoma and Ecchymosis
Coronary Artery Disease (CAD) is the most common cardiovascular system disease. According to the World Health Organization data, CAD ranks first among the top 10 causes of death.
- Trial name
- NCT05553821
- Testing
- Cold sand bag, A sand bag
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Eskisehir Osmangazi University
Appendicitis, Yersinia Enterocolitica Infection
Explanations for Negative Laparoscopic Appendectomies and Normal Laparoscopies
Trial The aim of the study is to investigate which infectious diseases might mimic the symptoms of acute appendicitis to a degree to cause a diagnostic laparoscopy or laparoscopic appendectomy.
- Conditions
- Appendicitis, Yersinia Enterocolitica Infection, Yersinia Pseudotuberculosis Infections, Appendectomy
- Trial name
- NCT03349814
- Testing
- Diagnostic laparoscopy without appendectomy, Diagnostic laparoscopy with appendectomy
- Where
- Denmark
- Volunteers
- 225 people
- Sponsor
- Herlev Hospital
Hepatocellular Carcinoma (HCC), Radiotherapy, Adjuvant
Adjuvant Radiotherapy of Sintilimab Versus TACE for HCC
This study is an open-label, randomized controlled, multicenter, phase III clinical trial
- Conditions
- Hepatocellular Carcinoma (HCC), Radiotherapy, Adjuvant, Immune Checkpoint Inhibitor, TACE
- Trial name
- NCT07186621
- Testing
- Sintilimab, radiotherapy, TACE
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Infant, Premature
Less Invasive Beractant Administration in Preterm Infants
The aim of this study is to assess the efficacy and feasibility of a new less invasive surfactant administration (LISA) technique with a specific designed cannula for surfactant administration using Beractant replacement in…
- Trial name
- NCT02611284
- Testing
- LISA, INSURE
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Chronic Apical Periodontitis
The Effect of Different Sodium Hypochlorite Concentrations and Activation Techniques on Postoperative Pain
The goal of this clinical trial was to evaluate the effect of different sodium hypochlorite (NaOCl) concentrations and irrigation activation techniques on the intensity of postoperative pain following single-visit root canal…
- Trial name
- NCT07033247
- Testing
- EDDY Sonic Activation System, Passive Ultrasonic Irrigation (PUI)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Cukurova University
GERD
Understanding the Pathophysiology and Effects of Diaphragmatic Breathing in Upright Gastroesophageal Reflux
This study aims to understand why patients have predominantly upright gastroesophageal reflux disease by comparing such patients to healthy persons AND whether a behavioral intervention (diaphragmatic breathing) will impact this…
- Trial name
- NCT02972047
- Testing
- Diaphragmatic Breathing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Inflammatory Bowel Disease, Crohn's Disease
Impact of Telemonitoring in the Management of Complex IBD in Spain: M-TECCU
M-TECCU is a study: multicenter, randomized and open. It consists of two parallel groups to compare the efficacy of the TECCU web-based telemonitoring system to achieve and maintain activity remission in patients with…
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis, Telemedicine
- Trial name
- M-TECCU (NCT06031038)
- Testing
- TECCU Software
- Where
- 30 sites in Spain
- Volunteers
- 290 people
- Sponsor
- Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.