Clinical trials: Intervention Group
Cardiovascular Disease, Stroke
A Personalized Dashboard to Educate Veterans at Risk of Stroke
Personalized risk communication methods have been used to educate patients that are at a high risk of developing cardiovascular disease.
- Trial name
- NCT01133171
- Testing
- Nurse Alone, Dashboard Plus Nurse
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- VA Office of Research and Development
Lateral Canthal Lines
MT10109L in the Treatment of Lateral Canthal Lines
To evaluate the safety and efficacy of MT10109L in the treatment of lateral canthal lines (LCL) in participants with moderate to severe LCL.
- Trial name
- NCT03785145
- Testing
- MT10109L
- Where
- 14 sites in United States, Russia and 1 more
- Volunteers
- 235 people
- Sponsor
- Medy-Tox
Shoulder Pain
Effectiveness of Dry Needling and Physical Therapy Versus Physical Therapy Alone Following Shoulder Stabilization Repair
The purpose of this single-blinded, randomized clinical trial is to determine the effectiveness of dry needling compared to a standard shoulder rehabilitation program on range of motion, functional movement, and pain in patients…
- Trial name
- NCT02704975
- Testing
- Rehabilitation and Dry Needling, Rehabilitation
- Volunteers
- 39 people
- Sponsor
- Keller Army Community Hospital
Central Venous Catheter Exit Site Infection, Catheter-Related Infections
Comparing CHG I.V. Securement Dressing With Transparent Dressing for Evaluation of Antimicrobial Efficacy
This is a single-center, prospective, randomized controlled clinical trial designed to compare the antimicrobial efficacy of Tegaderm CHG I.V.
- Trial name
- NCT04906512
- Testing
- 3M™ Tegaderm™ CHG I.V. Securement Dressing, 3M™ Tegaderm™ Transparent Film Dressing 1626W
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Solventum US LLC
Alcohol-Related Disorders, Alcohol Drinking
Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home
The purpose of this research study is to develop and test a care model to treat excessive drinking and alcohol use disorders in the primary care setting.
- Conditions
- Alcohol-Related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
- Trial name
- NCT02885311
- Testing
- Motivation Enhancement Therapy, Modified Behavioral Self-Control Therapy, Naltrexone
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Family Relationship, Stress
Impact of Increased Parent Presence in the Neonatal Intensive Care Unit on Parent & Infant Outcomes
The purpose of this pilot study is to compare parent and infant outcomes and unit outcomes pre and post a planned unit-wide intervention aimed at increasing parent presence in the Neonatal Intensive Care Unit (NICU).
- Conditions
- Family Relationship, Stress, Breastfeeding, Bottle Feeding
- Trial name
- NCT02901665
- Testing
- FCC intervention
- Where
- 2 sites in United States
- Volunteers
- 191 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Frailty, Malnutrition
Frail2Fit Study: Online Nutrition and Exercise Support for Older Adults With Frailty
Frail2Fit will explore the feasibility of training volunteers to deliver online nutrition, exercise, and behaviour change (supported self-management) to improve the health of older people after discharge from hospital.
- Conditions
- Frailty, Malnutrition, Sedentary Behavior
- Trial name
- NCT05384730
- Testing
- Group nutrition and exercise support
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
PCOS
Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS)
In women with polycystic ovary syndrome (PCOS), the cardinal physiological abnormality is excessive ovarian androgen production marked by increased serum testosterone (T) and androstenedione (A) levels.
- Trial name
- NCT01154192
- Testing
- Dexamethasone, recombinant human chorionic gonadotropin (r-hCG)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Diabetes Mellitus, Type 2
A Sleep Intervention (SLEEP-Extend) for Young Adults At-Risk for Type 2 Diabetes
The study is a prospective unblinded randomized trial to evaluate the feasibility of conducting a sleep extension intervention trial and the sleep extension intervention among the young adults.
- Trial name
- NCT03616171
- Testing
- SLEEP-Extend intervention, Control
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Emory University
Hypertension, Medication Adherence
Behavioral Economics to Improve Antihypertensive Therapy Adherence
Hypertension represents a major cardiovascular risk factor that can be controlled through the use of medications, yet medication non-adherence represents a common problem that leaves patients at elevated risk for adverse…
- Trial name
- BETA (NCT04029883)
- Testing
- Text Message, Behavior Economic Incentive
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Breathing-Related Sleep Disorder
A Pilot Study to Assess the Effects of a Novel Application of Averaged Volume Assured Pressure Support Ventilation (AVAPS-AE) Therapy on Re-hospitalization in Patients With Sleep-Disordered Breathing With Co-morbid COPD
This is a multicenter, randomized, parallel-group, open label study of the efficacy of AVAPS-AE to prevent re-hospitalization in hospitalized patients with comorbid Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- STOP-BBACK (NCT02446769)
- Testing
- AVAPS-AE Non-invasive ventilation therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Philips Respironics
Pregnancy, Postpartum
Pilot Testing a Mobile App to Designed to Increase Physical Activity Among Pregnant and Postpartum Women
The goal of this pilot project is to test the feasibility and potential efficacy of the evidence-based mHealth app (BumptUp) for improving physical activity and subsequent health outcomes (i.e.
- Trial name
- NCT04480931
- Testing
- mHealth Intervention Group, Educational Brochure
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
Diabetes Mellitus, Type 2, Newly Diagnosed
Effect of Different Interventions on Glycemic Control and β-cell Function in Newly Diagnosed Type 2 Diabetic Patients
The purpose of this study is to investigate and evaluate the effects of different interventions (1. exenatide, 2. insulin, 3. thiazolidinedione) on glycemic control and β-cell function in newly diagnosed drug-naïve type 2…
- Trial name
- NCT01147627
- Testing
- exenatide injection, Mixed Protamine Zinc Recombinant Human Insulin Lispro 25R, Pioglitazone
- Where
- 25 sites in China
- Volunteers
- 416 people
- Sponsor
- Sun Yat-sen University
Depression, Anxiety
Mechanisms of Mindfulness-based Interventions
Mindfulness-based Interventions (MBIs) are a family of standardized cognitive and behavioral therapies that focus on cultivating mindfulness-related skills for improving maladaptive cognitive, emotional, and behavioral processes.
- Conditions
- Depression, Anxiety, Stress
- Trial name
- MBI (NCT03571386)
- Testing
- Mindfulness-based Cognitive Therapy (MBCT), Mindfulness-based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Vanderbilt University Medical Center
Autism or Autistic Traits, Mental Health Disorder
The Effects of Executive Functions and Social Cognition on Mental Health
The objective of this study is to analyze the effects of executive functions (EFs) and social-cognitive abilities on the associations between autistic traits and mental health indicators (depression, anxiety, and stress).
- Conditions
- Autism or Autistic Traits, Mental Health Disorder, Executive Dysfunction, Social Cognition
- Trial name
- NCT06213194
- Testing
- MindZone
- Where
- Turkey (Türkiye)
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Ibn Haldun University
Alzheimer's Disease
A Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease
The purpose of this study is to evaluate the changes in the cognitive, functional, behavioral and global domains based on the different applicable psychometric batteries and scales.
- Trial name
- AMBAR (NCT01561053)
- Testing
- Albumin 5%, Albumin 20%, Immunoglobulin
- Where
- 40 sites in United States, Spain
- Volunteers
- 347 people
- Sponsor
- Instituto Grifols, S.A.
Joint Disease, Rheumatoid Arthritis
an On-demand Program to EmpoweR Active Self-management (OPERAS)
Self-management is a key component of successful chronic disease management and patients can benefit from learning about how daily activities and treatments relate to their symptoms and health status on an ongoing basis.
- Trial name
- OPERAS (NCT03404245)
- Testing
- Education, Fitbit/self-management app, physiotherapist counselling., Same intervention with a 6 month delay
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- University of British Columbia
Pediatric Pateints, Amnesic Properties of Propofol
A Pilot Study to Assess the Amnesic Properties of Propofol in Pediatric Patients
The goal of this study is to extend findings of propofol's effects on memory, as measured in volunteer research studies, to a clinical setting.
- Trial name
- NCT02278003
- Testing
- memory test, Propofol
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cirrhosis, Liver
Cirrhosis Medical Home
To address the health care system's lack of care coordination, the Institute of Medicine and Centers for Medicare and Medicaid Services recommend the development of collaborative care models (CCM) in a wide range of clinical…
- Trial name
- CMH (NCT04581369)
- Testing
- Care Coordinator Intervention for Direct Intervention Group, Care Coordinator Intervention for Standard of Care Group, Caregiver Intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Indiana University
Obesity
Assessment of and Treatment Applied to Food Addiction in a Rural Healthy Behaviors Clinic
Research purpose: The purpose of this pilot study is to assess obese clients for two phenotypes, those testing positive and those testing negative for Food Addiction (FA) (Yale Food Addiction Scale, YFAS) and determining the…
- Trial name
- NCT03431831
- Testing
- Intervention Control, Counselling, Contrave
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
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