Clinical trials: Intervention Group
Anxiety Disorders, Depression
Project COPE (Coping Options for Parent Empowerment)
The purpose of this research study is to collect information to better understand caregiver responses to COVID-19 stress and to help caregivers of children with Autism Spectrum Disorder (ASD) cope with these stressors.
- Trial name
- NCT04715906
- Testing
- UP-Caregiver
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Miami
Smoking Reduction, Tobacco Use
Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment
This pragmatic trial will evaluate the value of routinely providing proactive smoking cessation support to current smokers as a part of participating in lung cancer screening within Veterans Health Administration.
- Conditions
- Smoking Reduction, Tobacco Use, Tobacco Smoking, Tomography
- Trial name
- PROACT (NCT03612804)
- Testing
- Unsigned note to provider about cessation medication prescription, Proactive Telephone Counseling from VA Quitline
- Where
- 3 sites in United States
- Volunteers
- 944 people
- Sponsor
- VA Office of Research and Development
Hypertriglyceridemia, Metabolic Syndrome
Study to Assess Tricor Therapy Effectiveness in Patients With Metabolic Syndrome (TRISTAN)
This study is a prospective observational program within the frames of which Tricor (fenofibrate) is prescribed to patients with hypertriglyceridemia within a routine procedure as a part of the combination therapy with statins.
- Trial name
- TRISTAN (NCT04650152)
- Testing
- Tricor (fenofibrate), 145 mg, film-coated tablet
- Where
- 63 sites in Russia
- Volunteers
- 1,000 people
- Sponsor
- Abbott
End-stage Renal Disease
The Protective Effect of Remote Ischemic Conditioning on Residual Renal Function in Hemodialysis Patients (RIC-HD)
Hemodialysis (HD) is the main renal replacement therapy for patients with end-stage renal disease. However, factors such as hemodynamic instability can lead to gradual loss of residual renal function (RRF) in HD patients.
- Trial name
- RIC-HD (NCT06275152)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yuanjun Yang
Functional Mitral Regurgitation, Heart Failure
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
The objective of this prospective, randomized, double- blinded (patient and assessors), sham-controlled clinical trial is to assess the safety and efficacy of the CMCS in treating heart failure with functional regurgitation (FMR).
- Conditions
- Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases
- Trial name
- NCT03142152
- Testing
- Carillon Mitral Contour System, Guideline Directed Heart Failure Medication
- Where
- 92 sites in United States, Canada and 6 more
- Volunteers
- 300 people
- Sponsor
- Cardiac Dimensions, Inc.
Stroke
Effects of Touch Massage in the Sub-acute Phase After Stroke
The aim is to study effects of touch massage in the sub-acute phase after stroke in two main areas; general health and independence.The hypothesis are that; touch massage in the sub-acute phase after stroke decreases anxiety and…
- Trial name
- MEST (NCT01883947)
- Testing
- Touch massage, non-TENS
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Healthy Volunteers
A Comparative Study on Local Allergic Responses of Bee Venom and Essential Bee Venom Pharmacopuncture
This double-blinded randomized clinical trial investigates any differences in allergic responses elicited by Bee Venom (BV) and Essential Bee Venom (eBV).
- Trial name
- NCT02364349
- Testing
- Bee Venom (BV), Essential Bee Venom (e-BV)
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jaseng Hospital of Korean Medicine
Injuries
Common Recreational Diving Practices: A Randomized Control Trial Using Pre-Dive Checklist
To evaluate the efficacy of using a pre-dive checklist to prevent the incidence of diving mishaps in recreational divers.
- Trial name
- Checklists (NCT01960738)
- Testing
- A pre-dive checklist
- Where
- 4 sites in United States, Cayman Islands and 1 more
- Volunteers
- 1,116 people, healthy volunteers welcome
- Sponsor
- Divers Alert Network
Lateral Ankle Instability
Modified Brostrӧm Procedure With and Without Possible Arthroscopy for Lateral Ankle Instability
This study is to show that the investigators believe the Modified Brostrӧm Procedure (MBP) can be completed without a routine ankle arthroscopy.
- Trial name
- NCT02470338
- Testing
- MBP plus arthroscopy (Group A), MBP alone (Group B)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Edna Rath
Psychosocial Problem, Problematic Behavior in Children
Triple P With Pediatric Residents
The objective of this study is to conduct a randomized control trial to evaluate the impact of Triple P on the clinic practice of pediatric residents and on select parent and child outcomes.
- Conditions
- Psychosocial Problem, Problematic Behavior in Children, Parenting
- Trial name
- NCT01946958
- Testing
- Training in PC Triple P, Care As Usual
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Liver Malignant Tumors, Cholangiocarcinoma Metastatic
High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies
Over the past three decades, the treatment of both primary and secondary liver malignancies has been improved by the development and optimization of multiple minimally invasive thermal ablative therapies.
- Conditions
- Liver Malignant Tumors, Cholangiocarcinoma Metastatic, Pancreatic Cancer, Melanoma
- Trial name
- NCT05053555
- Testing
- high dose rate brachytherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Body Composition
Effect of Cinnamon Powder Capsules on Body Composition
Obesity is a global health concern that significantly affects individuals, and its prevalence is still rising at an alarming rate. While various treatments are available, they often come with unwanted side effects.
- Trial name
- NCT06119555
- Testing
- Cinnamon Capsules
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Sleep Wake Disorders
Testing Methods to Increase the Frequency of Lucid Dreaming
This study investigates the impact of lucid dreaming on individuals and explores methods to increase the likelihood of inducing lucid dreams intentionally.
- Trial name
- RRF (NCT06440226)
- Testing
- Eye Movement Technique, Memory Recall of Previous Night's Thoughts, Recall of Previous Lucid Dreams
- Where
- United Kingdom
- Volunteers
- 101 people
- Sponsor
- Abdulraheem Mohamed Gouda
Acetabular Fracture, Heterotopic Ossification
Heterotopic Ossification Prophylaxis
One complication that can occur after surgery on the acetabulum is the development of bone in abnormal places such as muscle and soft tissues.
- Trial name
- NCT04867278
- Testing
- External Beam Radiation (XRT), Debridement
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Maryland, Baltimore
Febrile Neutropenia, Pharmacokinetics
Population Pharmacokinetics/Pharmacodynamics of Carbapenems in Febrile Neutropenia Patients
1. Evaluating the differences in the efficacy and safety of meropenem optimal dosing regimen predicted by the PPK/PD model combined with MAPB method for patients with malignant hematological myelopathy accompanied by fever, as…
- Conditions
- Febrile Neutropenia, Pharmacokinetics, Pharmacodynamic, Carbapenems
- Trial name
- NCT05665478
- Testing
- Dose prediction using population pharmacokinetic models
- Volunteers
- 100 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Esophageal Varices
A Prospective, Multicenter, Randomized Controlled Trial Investigating the Impact of Fasting Duration on Postoperative Rebleeding Following Esophageal Variceal Ligation.
To evaluate the efficacy and safety of early postoperative oral intake (with a fasting period of 6 hours) versus delayed postoperative oral intake (with fasting periods of 24 hours or 48 hours) in patients with cirrhosis…
- Trial name
- NCT07774143
- Testing
- fasting periods of 24 hours, fasting periods of 48 hours, fasting periods of 6 hours
- Where
- 12 sites in China
- Volunteers
- 339 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Cirrhosis, Liver, Cirrhotic Cardiomyopathy
Echocardiography-guided Cirrhosis and Liver Failure-Intensive Care Protocol Sepsis
Point-of-care echocardiography is used to guide septic shock resuscitation in patients with severe sepsis in the intensive care unit (ICU), but without systematic evidence for efficacy in critically patients with Cirrhosis and…
- Conditions
- Cirrhosis, Liver, Cirrhotic Cardiomyopathy, Septic Shock
- Trial name
- ECLIPSE-I (NCT07286643)
- Testing
- POCUS, Fixed Resuscitation Strategy based on Target MAP
- Where
- India
- Volunteers
- 140 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Bullous Keratopathy
Amniotic Membrane Graft In Syntomathic Bullous Keratopathy
The amniotic membrane (AM) is an avascular structure derived from fetus, which is a good choice for regenerative medicine and effective treatment in eye surface pathologies such as bullous keratopathy (BK).
- Trial name
- AMBUK (NCT01926535)
- Testing
- Implant of amniotic membrane grafts, Therapeutic contact lenses
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Universidad de Valparaiso
Myocardial Infarction
The Pressure-controlled Intermittent Coronary Sinus Occlusion on VentrIcular PERformance Study
The PICSO ViPER study is a prospective single centre cohort study of the use of PICSO in patients presenting acute myocardial infarction and impaired function of the left ventricle and candidate to angioplasty the left anterior…
- Trial name
- PICSO-ViPER (NCT04032925)
- Testing
- PICSO
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Oxford University Hospitals NHS Trust
Health Promotion
Extended Evaluation of School-based Health Promotion Programmes in Bihar, India
SEHER Plus- Strengthening Evidence base on scHool-based intErventions for pRomoting adolescent health, seeks to evaluate a school based adolescent health promotion intervention delivered by two different delivery agents viz.
- Trial name
- SEHER+ (NCT02907125)
- Testing
- SEHER Intervention delivered by TSM, SEHER Intervention delivered by SM, Tarang AEP
- Where
- India
- Volunteers
- 29,527 people, healthy volunteers welcome
- Sponsor
- Sangath
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