Clinical trials: Intervention Group
Decision Support Systems,Clinical, Skin Diseases
The Impact of a Dermatology Information Source on Skin Problem Outcomes in Primary Care
Health care providers use a variety of computerized medical information sources to reduce knowledge gaps and support patient care decisions.
- Trial name
- NCT02922738
- Testing
- VisualDx
- Volunteers
- 465 people
- Sponsor
- University of Vermont
Proliferative Diabetic Retinopathy, Vitreous Hemorrhage
Anti-VEGF vs. Prompt Vitrectomy for VH From PDR
Although vitreous hemorrhage (VH) from proliferative diabetic retinopathy (PDR) can cause acute and dramatic vision loss for patients with diabetes, there is no current, evidence-based clinical guidance as to what treatment…
- Trial name
- AB (NCT02858076)
- Testing
- 2-mg Intravitreous Aflibercept Injection, Prompt Vitrectomy Plus Panretinal Photocoagulation
- Where
- 62 sites in United States, Canada
- Volunteers
- 205 people
- Sponsor
- Jaeb Center for Health Research
Depression, Pre-Exposure Prophylaxis
Friendship Bench Mental Health Intervention for Adolescent Girls and Young Women in South African PrEP Delivery Settings
Adolescent girls and young women (AGYW) at risk of HIV in sub-Saharan Africa, frequently (20-50%) have symptoms of common mental disorders, including depression, anxiety, and stress.
- Trial name
- NCT05664490
- Testing
- Youth Friendship Bench SA
- Where
- South Africa
- Volunteers
- 116 people
- Sponsor
- University of California, San Francisco
Postoperative Pain
Ropivacaine Transversus Abdominis Plane Blocks for Cesarean Section Analgesia
With this research the investigators hope to determine the lowest dose of ropivacaine used in transversus abdominis plane (TAP) blocks that can effectively treat pain in women after cesarean section (c-section).
- Trial name
- TAPROPI (NCT02893423)
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Cardiac Arrest
Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest
The purpose of this study is to assess the feasibility of hemofiltration in patients resuscitated from cardiac arrest. Cardiac arrest is the loss of mechanical activity of the heart including the loss of detectable pulse, or…
- Trial name
- NCT01509040
- Testing
- Standard Care, Low Volume Hemofiltration, High Volume Hemofiltration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Washington
Diabetes, Pregnancy
Early Screening and Treatment of Women With Prediabetes in Pregnancy
The investigators hope to learn whether treatment with medical nutrition therapy (MNT) for pregnant women with prediabetes decreases the rate and severity of impaired glucose tolerance later in pregnancy and improves perinatal…
- Trial name
- NCT01552213
- Testing
- Minimum intervention control group, Treatment for glucose intolerance
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- Stanford University
Opioid-Related Disorders
Trial of Adherence App for Buprenorphine Treatment (TAAB) Study
The purpose of this study is to pilot test a smartphone application that allows video-based directly observed therapy for participants receiving buprenorphine treatment for opioid use disorder in office-based settings.
- Trial name
- NCT03779997
- Testing
- Video-based DOT Application
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- University of Washington
Traumatic Amputation of Lower Extremity
Functional Electrical Stimulation Use in Trans-tibial Amputations
The purpose of this study is to demonstrate the efficacy of functional electrical stimulation (FES) for trans-tibial amputees. The investigators aim to demonstrate that providing three months of FES intervention will increase…
- Trial name
- NCT02931396
- Testing
- FES
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Alicia Koontz
Obesity
Approaches for Improving Long-term Weight Loss
The purpose of this study is to examine two approaches for improving long-term weight loss success. All participants will receive a 12-week, in-person standard behavioral weight loss program followed by either 12 weeks of yoga…
- Trial name
- NCT03799289
- Testing
- Behavioral weight loss followed by yoga instruction, Behavioral weight loss followed by cooking/dietary education instruction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Chronic Plaque Psoriasis
The Effect Of Smoking Status Of The Patient On The Success Of Etanercept Therapy In Psoriasis
The main purpose of this study is to assess the effect of smoking status on the success of Etanercept therapy in patients with moderate-to-severe psoriasis.
- Trial name
- NCT02570750
- Testing
- QUESTIONNAIRE ON SMOKING HABITS
- Where
- 30 sites in Romania
- Volunteers
- 183 people
- Sponsor
- Pfizer
Anxiety Generalized, Quality of Life
A Problem Solving Intervention for Hospice Caregivers
Hospice care is conceptualized as quality compassionate care for people facing a life-limiting illness, with services that cover clinical care, pain management, and emotional and spiritual support tailored to patients' and…
- Conditions
- Anxiety Generalized, Quality of Life, Depression
- Trial name
- NCT03712410
- Testing
- PISCES
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- George Demiris, PhD
Paroxysmal Atrial Fibrillation
Comparison of PolarX and the Arctic Front Cryoballoons for PVI in Patients With Symptomatic Paroxysmal AF
Pulmonary vein isolation (PVI) is an effective treatment for atrial fibrillation (AF). Single shot devices are increasingly used for PVI.
- Trial name
- COMPARE-CRYO (NCT04704986)
- Testing
- PVI using the Arctic Front Cryoballoon (Medtronic), PVI using the PolarX Cryoballoon (Boston Scientific)
- Where
- 2 sites in Switzerland
- Volunteers
- 202 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lower Back Pain
Restorative Exercise for Strength Training and Operational Resilience (RESTORE) for Chronic or Recurrent Low Back Pain
The purpose of the study is to learn about the effect of integrative therapies on chronic or recurrent low back pain. The intervention called RESTORE (Restorative Exercises for Strength Training and Operational Resilience) is…
- Trial name
- RESTORE (NCT02132910)
- Testing
- RESTORE Intervention
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Overweight, Obesity
Study of a Healthy Lifestyle Intervention for Deaf Adults Who Are Overweight or Obese
The purpose of the Deaf Weight Wise study is to test a 16 week, evidence-based, comprehensive program to change obesity-related health behaviors in Deaf people who use American Sign Language (ASL) as their primary language.
- Trial name
- DWW (NCT01452269)
- Testing
- Deaf Weight Wise program
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Non-small Cell Lung Cancer
Neoadjuvant Itraconazole in Non-small Cell Lung Cancer
The purpose of this study is to determine the pharmacodynamics effects of itraconazole in early-stage non-small cell lung cancer.
- Trial name
- NCT02357836
- Testing
- Itraconazole
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Texas Southwestern Medical Center
Alcohol Drinking, Telemedicine
Mobile Health for Alcohol Use Disorders in Clinical Practice
This study evaluates the impact on risky drinking days and quality of life for patients with alcohol use disorder among patients who use a mobile health smart phone application.
- Trial name
- NCT04011644
- Testing
- A-CHESS self-monitored, A-CHESS peer-supported, A-CHESS clinically-integrated
- Where
- United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Aortic Aneurysm, Abdominal
Impact of Grafts and Endografts for Abdominal Aneurysms on Arterial Stiffness.
The purpose of this study is to evaluate by non-invasive methods the change in central hemodynamics and arterial stiffness produced by grafts and endografts after abdominal aortic aneurysm repair.
- Trial name
- NCT02642952
- Testing
- non-invasive methods
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Type 2 Diabetes
Home-based Diabetes-Modified Behavioral Activation Treatment for Low Income Seniors With T2DM
The objective of this protocol is to evaluate the efficacy and cost-effectiveness of 8 sessions of in-home, telephone-delivered, culturally-modified, manualized diabetes-modified, behavioral activation treatment (Home DM-BAT)…
- Trial name
- HOME DM-BAT (NCT04203147)
- Testing
- Supportive Therapy (Control), Home DM-BAT
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- State University of New York at Buffalo
Osteoarthritis, Knee, Osteoarthritis, Hip
OA Clinic-Community CARE Model
The purpose of this study is to test the OA Clinic-Community CARE Model (OA CARE) which will address all recommended components of knee/hip (osteoarthritis) OA care, include interventions for both patients and primary care…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Overweight, Obesity
- Trial name
- OA CARE (NCT05349500)
- Testing
- OA CARE Intervention, Usual Care control group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Recruitment
Advancing People of Color in Clinical Trials Now: Involvement in Trials Using a Patient-Centered Website: A Community-Engaged Approach
The purpose pf this study is to evaluate the comparative effectiveness of a culturally and linguistically tailored clinical trial literacy website in increasing likelihood of participating in clinical trials.
- Trial name
- ACT Now (NCT03243071)
- Testing
- Tailored Website, Standard Website
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
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