Clinical trials: Intervention Group
Severe Asthma, COPD
K-HEALTH in AIR - Barcelona Pilot - Cohort
The study protocol is part of the European (EU) project "Knowledge for improving indoor AIR quality and HEALTH" (K-HEALTHinAIR, 2022-2026 - registry 101057693), which focuses on enhancing our understanding of how poor indoor air…
- Trial name
- NCT06421402
- Testing
- Air quality monitoring at patient's home, Questionnaires: Baseline & every six months, Lung function Testing: Baseline & every six months & during exacerbations
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Writing Learning Disability
Biomechanical Assessment and Biofeedback-training System for Handwriting
The purpose of this study is to investigate the real-time kinetics of handwriting regarding the design of the utensil and fine motor performances from biomechanical perspectives. It includes three parts.
- Trial name
- NCT03822702
- Testing
- Biofeedback Training, Motor Training
- Where
- Taiwan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Polycystic Ovarian Syndrome, Obesity
Post-Prandial Liver Glucose Metabolism in PCOS
The Investigators will measure if hepatic metabolism is upregulated in obese girls with PCOS and hepatic steatosis (HS), compared to PCOS without HS and obese controls without HS.
- Conditions
- Polycystic Ovarian Syndrome, Obesity, Hepatic Steatosis
- Trial name
- PLUM (NCT03041129)
- Testing
- oral glucose tolerance test, MRI of liver
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Breast Cancer, Invasive Breast Carcinoma
Tissue- and Serum-Derived Exosomal microRNAs as Predictors of Neoadjuvant Chemotherapy Response in Breast Cancer
This prospective observational study aims to evaluate whether exosomal microRNA profiles derived from tumor tissue and blood serum are associated with pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in…
- Conditions
- Breast Cancer, Invasive Breast Carcinoma, Exosomal microRNA, Neoadjuvant Chemotherapy Response
- Trial name
- ExoTSS-BC (NCT07500129)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Atlas University
Breast Cancer Survivorship
Exercise to Improve Neurovascular Function in Breast Cancer Survivors
Study Rationale: Breast cancer survivors are more likely to develop cardiovascular disease (CVD) or neurocognitive disease than age-matched counterparts without a history of cancer diagnosis.
- Trial name
- PIONEER (NCT06925529)
- Testing
- Cardio-Oncology Rehabilitation and Exercise Programme
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Baker Heart and Diabetes Institute
Menopause
A Survey Evaluating Prevalence, Severity and Associated Factors in East Asian Women With Moderate-to-severe Menopause-related Vasomotor Symptoms (MR-VMS)
The purpose of this study is to estimate the prevalence of Vasomotor Symptoms (VMS) and prevalence of moderate to severe VMS in peri-menopausal women and post-menopausal women aged 40-65 in East Asia (China, South Korea and…
- Trial name
- NCT04553029
- Testing
- No intervention
- Where
- 3 sites in China, South Korea and 1 more
- Volunteers
- 3,399 people
- Sponsor
- Astellas Pharma Singapore Pte. Ltd.
Asphyxia Neonatorum, Morbidity;Newborn
Effects of Probiotic Mixture Supplementation and Evaluation of Intestinal Mucosal Tolerance and Gut Microbiome in Newborns With Perinatal Asphyxia Receiving Hypothermic Treatment
The VISNAT trial is a PILOT STUDY due to absence of previous evidences in literature on using probiotic in newborns with perinatal asphyxia.
- Trial name
- VISNAT (NCT04145713)
- Testing
- Probiotic mixture
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Surgical Stress Response, Stress Physiological
Feasibility of Breathwork Intervention With Older Adults After Knee Surgery
Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients.
- Conditions
- Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological
- Trial name
- NCT07464860
- Testing
- A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Pancreatic Cancer
Early Increase in Blood Flow (EIBS) in the Duodenum in Patients With Pancreatic Cancer
Pancreatic cancer is the fourth leading cause of cancer death in the United States and is associated with a poor prognosis. The average life expectancy after diagnosis is approximately 5 to 8 months.
- Trial name
- NCT01015820
- Testing
- EGD with EUS, 4D-ELF
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Mayo Clinic
Henoch-Schoenlein Purpura
The Research of Standard Diagnosis and Treatment for Severe HSP in Children
This study is performed to evaluate the efficacy and safety of various measures in the treatment of severe HSP in children.
- Trial name
- NCT02540720
- Testing
- Dexamethasone, Gamma globulin, Hemoperfusion
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing Children's Hospital
Cervical Cancer, Prevention
Primary HPV-based Cervical Cancer Screening Algorithms in Botswana
Primary high-risk human papillomavirus (HPV) testing has become first line screening for cervical cancer in high-income countries.
- Trial name
- NCT04242823
- Testing
- 8-type HPV genotype restriction
- Where
- Botswana
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Substance-related Disorders
Project CHOICE: Efficacy Testing of CHOICE and CHOICE+Normative Feedback Interventions
This study will use a pilot test format to examine the efficacy of a brief Motivational Interviewing (MI) intervention developed by the investigator Dr.
- Trial name
- CHOICE (NCT02083523)
- Testing
- Motivational Interview with Normative Feedback, Motivational Interview
- Volunteers
- 48 people
- Sponsor
- University of Illinois at Urbana-Champaign
Duchenne Muscular Dystrophy
Strength Training in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a debilitating neuromuscular disease that causes muscle breakdown, weakness, and eventual death.
- Trial name
- NCT02421523
- Testing
- Aim 2 Exercise group, Aim 1 Exercise Dosing, Aim 2 Control group
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Florida
Motor Activity, Weight Loss
Effect of a Technology-Based Intervention on Weight Change Post-Bariatric Surgery
The primary aim of this study is to examine the effect of applying a minimal contact technology-based intervention (TECH) at 1-year post-bariatric surgery on weight change compared to Standard Care.
- Trial name
- NCT02867696
- Testing
- Standard Care, Technology-based Intervention (TECH)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Lung Neoplasm, Melanoma
Clinical Trial of Telenursing for Monitoring Supportive Care Needs in Patients With Lung Cancer and Melanoma Candidates for the First Prescription of Targeted Therapies
Single-center, randomized clinical trial (RCT) with low intervention level (Telenursing), for the monitoring of patients affected by lung cancer and melanoma who are candidates for first prescription with Targeted Therapies.
- Trial name
- Telenursing (NCT06254196)
- Testing
- Telenursing interventions for monitoring Supportive Care Needs
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Regina Elena Cancer Institute
Spastic Cerebral Palsy (sCP)
Cuevas Medek Exercises to Improve Postural Control and Balance in Children With Spastic Cerebral Palsy
This study aims to evaluate the effects of Cuevas Medek Exercises on postural control and balance in children with spastic cerebral palsy.
- Trial name
- NCT07403162
- Testing
- Cuevas medek exercises, Conventional Therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Diabete Mellitus
Impact of Diabetes Continuing Education on Primary Health Care Physicians' Knowledge, Attitudes and Practice
The main objective is to evaluate the effectiveness of a continuing education program on the Knowledge, Attitudes and Practices of primary health care physicians towards a high quality of diabetes care in Aseer region, Saudi…
- Trial name
- NCT04027062
- Testing
- Diabetes Continuing Education Intervention
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- King Khalid University
Osteoarthritis, Knee
Biomechanical Footwear as a Non-invasive Alternative and Supplement to Total Knee Replacement
Osteoarthritis (OA), the most common type of arthritis, affects more than 32.5 million adults in the United States. It is also among the most expensive condition to treat when joint replacement surgery is required.
- Trial name
- NCT04732962
- Testing
- AposHealth, Total Knee Replacement (TKR)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Geisinger Clinic
Non-Alcoholic Steatohepatitis (NASH)
Evaluating the Efficacy and Safety of Roflumilast in Patients with NASH
Study type :clinical trial Main purpose :esnsure safety and efficacy of Roflumilast to treat patients with Non-Alcoholic Steatohepatitis Background and aim: Non-alcoholic fatty liver disease is the most prevalent chronic liver…
- Trial name
- NCT06677788
- Testing
- Roflumilast 500 Mcg Oral Tablet, Vitamin E capsule
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Tanta University
Gambling Disorder
Online Intervention to Promote Change and Help-Seeking in Young Adults With Gambling and Trading Problems
The goal of this study is to investigate if personalized online normative feedback (PONF) can increase intention to change and help-seeking behaviors in young adults with gambling or trading problems in Spain.
- Trial name
- NCT06681103
- Testing
- Personalized Normative Feedback
- Where
- Spain
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
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