Clinical trials: Ketorolac
Inflammation
Intravitreal Ketorolac for Chronic Uveitis: A Investigational Safety Study
Intraocular delivery of ketorolac will be an effective means to treat inflammation and macular edema and prevent structural complications and vision loss in patients with uveitis who are unable to tolerate corticosteroids due to…
- Trial name
- INCITE (NCT01164085)
- Testing
- Intravitreal Ketorolac
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University
Post-operative Nausea, Post-operative Vomiting
Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery
The purpose of this study is to determine whether a multi-modal anesthesia and pain control protocol reduces post-operative and post-discharge nausea and vomiting (PONV and PDNV) in patients undergoing upper jaw corrective…
- Conditions
- Post-operative Nausea, Post-operative Vomiting, Nausea Persistent
- Trial name
- NCT01592708
- Testing
- Antiemetic anesthesia protocol
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
A Comparison of Exparel Local Anesthetic in Total Knee Arthroplasty (TKA) Patients
This is a prospective, single-center, single-blinded, randomized, case-control study. The study is conducted by a single investigator at an orthopedic surgery institute, with a minimum 6 week post operative follow-up period of…
- Trial name
- NCT02765815
- Testing
- Liposomal bupivacaine, 266mg, Bupivacaine 0.5 % with Epinephrine, Ketorolac 30mg
- Where
- United States
- Sponsor
- Holy Cross Hospital, Florida
Idiopathic Scoliosis, Post-operative Pain
Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis
This study hypothesizes that the addition of a low-dose ketamine infusion to usual post-operative pain management will improve pain control as evidenced by an improvement in post-operative pain scores for patients undergoing…
- Trial name
- NCT02651324
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Albany Medical College
Bowel Obstruction
Adult Patients Undergoing Open Colectomy MA402S23B303
This study is designed to compare the standard of care against EXPAREL(R) to determine if total opioid consumption is reduced when using EXPAREL, therefore possibly reducing total hospitalization costs.
- Trial name
- IMPROVE-Open (NCT01507246)
- Testing
- IV morphine sulfate, EXPAREL (bupivacaine liposome injectable suspension)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Polytrauma
Inflammatory Markers in Trauma Patient Outcomes
It is unknown whether early modulation of inflammatory cytokines is associated with improved patient outcomes, reduced narcotic requirements in orthopaedic patient population, and improved patient subjective pain after hospital…
- Trial name
- NCT03671746
- Testing
- Ketorolac, Saline Solution
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Arun Aneja
Pain
Pharmacokinetics, Safety, and Efficacy of SPRIX in 12 to 17 Year Old Patients vs. Adult Patients Undergoing Open Surgical Procedures
A SPRIX trial in pediatric subjects vs. adults undergoing open surgical procedures resulting in at least a moderate pain level. Subjects will receive SPRIX and blood samples will be collected for pharmacokinetic (PK) assessment.
- Trial name
- NCT01819610
- Testing
- SPRIX
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- American Regent, Inc.
Migraine Disorders
A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescents
Migraine is a neurological disease characterized by severe and recurrent headaches. Children and adolescents with migraine often present to the emergency department (ED) with acute attacks, where migraine accounts for up to ~30%…
- Trial name
- NCT05102591
- Testing
- Ketorolac, Metoclopramide, Active Remote Electrical Neuromodulation Device
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Calgary
Cancer of Pancreas, Cancer of the Pancreas
Epidural Analgesia Use in Pancreatic Resections
The rationale for this study is to investigate the benefits of epidural analgesia in pancreatic resections in a prospective, single blind, randomized control trial.
- Conditions
- Cancer of Pancreas, Cancer of the Pancreas, Pancreas Cancer, Pancreas Neoplasms
- Trial name
- E-PRO I (NCT02681796)
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Washington University School of Medicine
Postoperative Pain
The Analgesic Efficacy of Magnesium and Ketorolac in Ultrasound Supraclavicular Block
Despite many regional anesthetic techniques have been described for anesthesia of the brachial plexus which is responsible for the sensory and motor innervation of entire upper limb, still, supraclavicular block (SCB) is the…
- Trial name
- NCT04554862
- Testing
- Magnesium sulfate, Ketorolac Tromethamine, supraclavicular block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Fayoum University Hospital
Low Back Pain
Morphine Versus Ketorolac in Low Back Pain
The study is prospective, double blinded, randomised controlled and has the purpose to compare the analgesic effects of ketorolac or morphine intravenous in low back pain.
- Trial name
- NCT02782286
- Testing
- Ketorolac, Morphine
- Volunteers
- 100 people
- Sponsor
- Loredana Ghinea
Anesthesia, Surgery
Low Dose Versus Normal Dose Ketorolac for Postoperative Pain After Prostatectomy and Hysterectomy
A monocenter, prospective, double-blind, randomized controlled non-inferiority trial will be designed to investigate if ketorolac 10 mg is as effective for pain relief as the standard dose of 30 mg in patients undergoing robot…
- Trial name
- NCT05206110
- Testing
- 10 mg IV ketorolac, 30 mg IV ketorolac
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Jessa Hospital
Pancreatitis
A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis
Determine if IV ketorolac is an effective agent in the prevention of post-ERCP pancreatitis. Determine if IV ketorolac provides improved post-procedure analgesia.
- Trial name
- NCT02465138
- Testing
- Ketorolac
- Where
- 2 sites in United States
- Sponsor
- University of California, San Francisco
Osteoarthritis (OA) of the Knee
Novel Extended-Release Bupivacaine Polymer for Sustained Pain Relief Following Total Knee Arthroplasty
Participants are being invited to take part in a research study about pain control after total knee replacement surgery (also called total knee arthroplasty or TKA).
- Trial name
- NCT07775248
- Testing
- Periarticular Injection, Adductor Canal Block, Bupivacaine-Meloxicam
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Henry Ford Health System
Pain, Postoperative
Dextromethorphan Use in Multimodal Analgesia Regimens for Total Knee Arthroplasty
Total knee arthroplasty (TKA) is one of the most painful orthopedic procedures. After TKA surgery, postoperative pain relief may be achieved using a variety of techniques.
- Trial name
- NCT02987920
- Testing
- Dextromethorphan, Acetaminophen, Oxycodone
- Volunteers
- 23 people
- Sponsor
- University of Southern California
Acute Renal Colic
Nasal Fentanyl And Renal Colic
The purpose of this study is to determine whether nasal fentanyl is effective in the treatment of renal colic in adults in emergency department.
- Trial name
- NCT01339624
- Testing
- FENTANYL, Ketorolac Tromethamine AND morphine
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Valduce Hospital
Cystoid Macular Edema After Phacoemulsification
Prophylactic Effect of Ketorolac Tromethamine on the Cystoid Macular Edema After Phacoemulsification in Diabetic Patients
The aim of the study is determining the prophylactic effect of ketorolac tromethamine drop 0.5% eye drop on the functional and anatomical ocular characteristics of the diabetic patients after the phacoemulsification surgery.
- Trial name
- NCT03551808
- Testing
- using of Ketorolac Tromethamine Eye Drop
- Where
- Iran
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Thoracic Neuritis
Ultrasound-guided Serratus Block and the Emergence of Post-thoracotomy Pain Syndrome
The aim of this prospective, single blinded, comparative pilot study is to evaluate U/S guided serratus anterior plane catheter block (SAPB) versus patient-controlled analgesia (PCA) on the emergence of post - thoracotomy pain…
- Trial name
- NCT03533426
- Testing
- Serratus anterior plane catheter block, Patient controlled analgesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Congenital Heart Disease in Children
Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
The proposed study will be a prospective, randomized, double blind, placebo controlled trial to compare the use of a continuous infusion versus intermittent ketorolac on postoperative patients in the pediatric cardiovascular ICU.
- Trial name
- CIVIK (NCT04040452)
- Testing
- Continuous ketorolac
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Phoenix Children's Hospital
Pain, Postoperative
Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty
Total shoulder arthroplasty (TSA) is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery.
- Trial name
- NCT02876055
- Testing
- Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic