Clinical trials: Manual therapy
PTSD, Smoking
Use of Technological Advances to Prevent Smoking Relapse Among Smokers With PTSD
The primary goal of the study is to evaluate the use of a new smart phone application in preventing relapse to smoking among people with PTSD.
- Trial name
- QUIT4EVER (NCT01990079)
- Testing
- Bupropion, nicotine replacement therapy, Smoking cessation counseling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Dental Caries Extending Into Dentin, Root Caries
Root Caries Excavation with Air Water/powder Prophylaxis Device for ART Restorations
The main objective of this RCT is to compare the efficacy of a powder/water jet prophylaxis device and conventional hand excavation in excavating root surface caries, with regard to restoration survival/success in older adults.
- Trial name
- ART-AIRFLOW (NCT04822246)
- Testing
- Control: Hand instrumentation for caries excavation, Intervention 1: EMS Airflow device for caries excavation, Intervention 2: Hand excavation + EMS Airflow device for caries excavation
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Cervical Syndrome
Treatment of Cervical Syndrome With Myofascial Therapies
This study aimed to investigate the effects of myofascial release therapy (MRT) for improving pressure pain thresholds (PPTs), range of motion and pain in patients with mechanical neck pain (NP).
- Trial name
- MRH (NCT03184220)
- Testing
- Physiotherapy treatment
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- University of Cadiz
Parkinson Disease, Depressive Symptoms
Online Cognitive Behavioral Therapy for Depressive Symptoms in Parkinson's Disease
More than 1 million people in Europe suffer from Parkinson's disease (PD), a brain disorder manifesting with a motor syndrome and several non-motor features.
- Conditions
- Parkinson Disease, Depressive Symptoms, Anxiety
- Trial name
- ePark (NCT05585827)
- Testing
- Online cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Helse Stavanger HF
Borderline Personality Disorder
Mapping Aspects of Psychotherapy in Dialectical Behavior Therapy
Although dialectical behavior therapy (DBT) skills training is effective in the treatment of borderline personality disorder, it contains four skills modules and there is little research to guide their modular application.
- Trial name
- MAP-DBT (NCT04626310)
- Testing
- Dialectical behavior therapy - emotion regulation skills training, Dialectical behavior therapy - interpersonal effectiveness skills training, Interpersonal psychotherapy
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Massachusetts, Amherst
Migraine
Multimodal Physiotherapy Intervention for People With Migraine
Migraine is one of the most prevalent primary headache disorders worldwide and is associated with substantial impairments in quality of life, work productivity, and psychosocial functioning.
- Trial name
- NCT07671703
- Testing
- Multimodal Treatment Program, Usual Care
- Where
- Germany
- Volunteers
- 195 people
- Sponsor
- Hochschule Osnabruck
Anesthesia, Local
Conventional Versus Computer-Assisted Dental Anesthesia
The purpose of this clinical trial was to compare two methods of delivering local dental anesthesia in undergraduate dental students: a computer-controlled local anesthetic delivery (CCLAD) system and a conventional dental…
- Trial name
- NCT07731503
- Testing
- Computer-Controlled Local Anesthetic Delivery System, Conventional Aspirating Dental Syringe
- Where
- Mexico
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Montemorelos
Lower Extremity Lymphedema
Diaphragmatic Exercises and Fascial Release Techniques on the Treatment of Lower Extremity Lymphedema
The aim of this study is to determine the effect of multidimensional breathing exercises and fascial release techniques performed in addition to the conventional treatment program on the treatment of lymphatic fluid in women with…
- Trial name
- NCT05483569
- Testing
- Complex Decongestive Physiotherapy, Multidimensional Diaphragmatic Breathing Exercises, Facial Release Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medeniyet University
Acute Ischemic Stroke Patients, Large Vessel Occlusion
A Comparison of Cyclic Manual Direct Aspiration Thrombectomy (Plunger Technique) vs. Static Manual Direct Aspiration Thrombectomy for Treatment of Acute Large Vessel Occlusion Stroke
This prospective, randomized controlled trial will compare two manual aspiration techniques for treating acute ischemic stroke due to large vessel occlusion: cyclic aspiration (Plunger technique) and static aspiration.
- Trial name
- Plunger (NCT07231380)
- Testing
- Plunger Technique, Static Manual Aspiration Thrombectomy
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Vanderbilt University Medical Center
Insomnia, Adults
A Theory-based Sleep Hygiene Education for Insomnia Disorder
Insomnia is a prevalent sleep disorder associated with numerous adverse health outcomes, including fatigue, irritability, and impaired daytime functioning.
- Trial name
- NCT07642479
- Testing
- Sleep Hygiene Education, CBT-I Apps
- Where
- Hong Kong
- Volunteers
- 264 people
- Sponsor
- The Hong Kong Polytechnic University
Anxiety, Vital Signs
The Effect of Acupressure Applied Before Suturing Procedure in the Emergency Department on Anxiety and Vital Signs
This study suggests that the anxiety experienced by patients during suturing in the emergency department can be reduced with acupressure and offers a research proposal on vital signs.
- Trial name
- NCT06636903
- Testing
- Acupressure
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Ezgi BOLAT
Obesity
A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet
In this study we will be looking into how CagriSema influences metabolism (the process by which food is used to supply energy for the body) compared to a diet. CagriSema is a new investigational medicine.
- Trial name
- NCT07184086
- Testing
- CagriSema (Cagrilintide B + semaglutide I), Low Energy Diet
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Novo Nordisk A/S
Vaginismus, Sexual Dysfunctions
Evaluation and Comparison of Women Pelvic Floor With and Without Sexual Dysfunction (Vaginismus)
Sexuality is considered one of the pillars of quality of life, an integral part of the personality of each individual. Being a basic human being need, it cannot be separated from other aspects of life.
- Conditions
- Vaginismus, Sexual Dysfunctions, Muscular Hypertonicity, Muscle Tone Poor
- Trial name
- NCT03176069
- Testing
- Evaluation and Comparison of women pelvic floor with and without sexual dysfunction, The physiotherapeutic treatment
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
High Tone Pelvic Floor Dysfunction
Comparing Adjuvant Treatments for High Tone Pelvic Floor Dysfunction
The researchers are comparing two treatments for high tone pelvic floor dysfunction (HTPFD) in conjunction with pelvic floor physical therapy (PFPT).
- Trial name
- NCT07404397
- Testing
- Cyclobenzaprine, Pelvic floor massage wand, Pelvic floor physical therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Aphasia Following Cerebral Infarction
Intensive Comprehensive Aphasia Programme for People With Post-Stroke Aphasia
Research question Does participation in an Intensive Comprehensive Aphasia Programme produce a meaningful change in the communication of people with aphasia, their quality of life and that of their carers? Background Aphasia is a…
- Trial name
- RCT of an ICAP (NCT07386652)
- Testing
- ICAP, Standard Care (in control arm)
- Where
- United Kingdom
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University College, London
Shoulder Impingement Syndrome, Shoulder Rotator Cuff Tendinopathy
Effectiveness of Supervised Motor Control Exercises on Rotator Cuff Tendinopathies
The shoulder is the most mobile joint in the body but still has the responsibility of ensuring a strong stability of our upper limbs during daily activities.
- Trial name
- NCT02926443
- Testing
- Upper Extremity Neuromuscular Training Program, Usual Physiotherapy Care
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Laval University
Low Back Pain, Recurrent, Chronic Low Back Pain (CLBP)
Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy
The purpose of this study is to quantify Magnetic Resonance Elastography (MRE)-derived mechanical property biomarkers of the lumbar paraspinal musculature and associated myofascial tissue regions before and after the intervention.
- Trial name
- NCT07712458
- Testing
- EMMA (Expert Manipulative Massage Automation)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Mayo Clinic
Cardiac Valve Disease
Preoperative Optimization of Cardiac Valve Patients' Expectations
Recovery after surgery depends on psychological factors such as preoperative information, expectations and surgery-associated anxiety.
- Trial name
- ValvEx (NCT04502121)
- Testing
- EXPECT: Preoperative optimization of cardiac valve patient's expectations
- Where
- Germany
- Volunteers
- 89 people
- Sponsor
- Philipps University Marburg
Cervical Dystonia
Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia
The purpose of the proposed research is to determine if Osteopathic manipulative medicine (OMM) used alone or in combination with the standard treatment of botulinum toxin intramuscular injections improves motor function and…
- Trial name
- NCT02420106
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York Institute of Technology
Arthritis
Fascial Manipulation® Associated With Standard Care Versus Standard Post-surgical Care for Total Hip Arthroplasty
Post-surgical physiotherapy programs following to total hip arthroplasty (THA) show important differences between types and numbers of treatment sessions.
- Trial name
- NCT02576028
- Testing
- Fascial Manipulation® (FM), standard active exercises
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Bolognini di Seriate Bergamo
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