Clinical trials: Metronidazole
Paraplegia, Tetraplegia
Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI
A study comparing short-term delivery of epidural spinal stimulation versus transcutaneous spinal stimulation.
- Conditions
- Paraplegia, Tetraplegia, Paralysis, Quadraplegia
- Trial name
- NCT05095454
- Testing
- Percutaneous epidural electrical spinal stimulation, Transcutaneous electrical spinal stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Kristin Zhao, PhD
Pouchitis
A Study to Learn About the Safety of Vedolizumab and How Well it Works in Children and Teenagers With Active Chronic Pouchitis
When some people have their large bowel removed, a surgeon can make a "pouch" from part of the small bowel to connect it to the back passage (anus). Pouchitis is when the pouch becomes inflamed (swollen) or infected.
- Trial name
- NCT06443502
- Testing
- Vedolizumab, Concomitant Antibiotic Therapy
- Where
- 14 sites in Belgium, Croatia and 6 more
- Volunteers
- 30 people
- Sponsor
- Takeda
Diabetes Mellitus Type 2, Continuous Glucose Measurement
Effectiveness of Individualized Automatic Coaching Message for Glycemic Management and Depressive Symptom
This is a 12-week, single-center, randomized, prospective, confirmatory study of effectiveness of the individualized automatic coaching messages for glycemic management based on continuous glucose monitoring and depressive…
- Conditions
- Diabetes Mellitus Type 2, Continuous Glucose Measurement, Depressive Symptom
- Trial name
- NCT06769906
- Testing
- Individualized automatic coaching message for glycemic management and depressive symptom
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Samsung Medical Center
Bladder Cancer
Application-based Perioperative Management of the Radical Cystectomy Patient
The purpose of this study is to learn whether it is feasible to use the LifeScience Technologies application (LST app) in patients undergoing radical cystectomy with the eventual goal to reduce complications and readmissions to…
- Trial name
- NCT02942121
- Testing
- LifeScience Technologies application
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Alveolar Osteitis
Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar Osteitis
This study will compare the effectiveness of amoxicillin, metronidazole, and chlorhexidine in preventing alveolar osteitis (dry socket) following lower third molar extraction.
- Trial name
- NCT07833176
- Testing
- Amoxicillin, Metronidazole, Chlorhexidine
- Where
- Pakistan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Stroke, Acute, Gait, Hemiplegic
Biomarkers of Independent Walking Post-Stroke
Prediction of walking recovery after stroke can inform patient-centered care and support discharge planning. The accuracy of current prediction models is limited, however, due to small study designs and narrow predictors…
- Trial name
- NCT05004389
- Testing
- MRI, blood draw, Clinical assessments
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Vermont
Helicobacter Pylori
Personalized vs Standard of Care Treatment for Helicobacter Pylori Eradication Among Veterans
The primary objective of this study is to compare the Helicobacter pylori (H. pylori) eradication rate following empiric bismuth-based quadruple therapy (BQT) versus a personalized H.
- Trial name
- VA EradicateHP (NCT07104318)
- Testing
- Bismuth quadruple therapy with optimized proton pump inhibitor (PPI), Bismuth quadruple therapy with standard proton pump inhibitor (PPI), Clarithromycin triple therapy with optimized proton pump inhibitor (PPI)
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- VA Office of Research and Development
Chronic Endometritis
Εffectiveness of Intrauterine Antibiotic Administration for Treatment of Chronic Endometritis
Chronic Endometritis (CE) is related to infertility and entails a challenging management. This study investigates the treatment of off-label intrauterine antibiotic infusion either separately or combined with oral antibiotic…
- Trial name
- NCT05205993
- Testing
- Intrauterine infusion, Oral administration
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Genesis Athens Clinic
Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
RCT: Triple vs Sequential vs Concomitant Therapy H Pylori
Triple therapy (TT) comprising proton pump inhibitor (PPI), amoxicillin 1g and clarithromycin 500mg twice daily has long been considered one of the standard treatment for H.
- Trial name
- NCT02092506
- Testing
- 10 day triple therapy, 10 day sequential therapy, 10 day concomitant therapy
- Where
- Singapore
- Volunteers
- 462 people
- Sponsor
- Changi General Hospital
Non-steroidal Anti-inflammatory Drug Adverse Reaction
Research for Prevention and Treatment of NSAIDs Related Gastrointestinal Side Effects
We aim to evaluate the protective effects of eradication of HP and continue using Geranylgeranylacetone (GGA) on NSAIDs related gastroenterological lesions.
- Trial name
- NCT01547559
- Testing
- part1:teprenone, part1:EAC-T, part1:EA-EMC-T
- Where
- 2 sites in China
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Physician-Patient Relations, Diabetes Mellitus, Type 2
Improving Relationships Using Motivational Interviewing
This research aims to optimize patient-clinician relationships through motivational interviewing training in a Federally Qualified Health Center (FQHC) to improve health outcomes for African American patients with Type 2 diabetes.
- Trial name
- IRMIT (NCT05696964)
- Testing
- Motivational interviewing training enhanced with artificial intelligence
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wright State University
Simulation Training
Metric-based Feedback Training for the Acquisition of Sonographic Skills
The investigators hypothesized that feedback based on previously developed and validated metrics will improve novices' learning of procedural skills.
- Trial name
- NCT02976623
- Testing
- metric-based feedback training
- Where
- Ireland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University College Cork
Dietary Habits
Analysis of MicroBial Metabolites After Eating Refined Food
The purpose of this study is to learn more about what happens in the human body after consuming a meal that contains ultra-processed foods like hamburgers, and if this is different to what happens after consuming a meal that…
- Trial name
- AMBER (NCT04308473)
- Testing
- Ultra-processed Food Meal, Whole Food Meal
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Enhanced Recovery After Surgery, Appendicitis
Safety and Efficacy of ERAS Therapeutic Protocol for Complicated Appendicitis in Children
Complicated appendicitis in pediatrics is frequent, potentially serious and complex to manage. The implementation of a ERAS model would allow optimizing perioperative care, offering a shorter hospital stay, reducing complications…
- Conditions
- Enhanced Recovery After Surgery, Appendicitis, Children, Only
- Trial name
- ERAS (NCT05511194)
- Testing
- Enhanced Recovery After Surgery therapeutic protocol, Conventional management
- Volunteers
- 40 people
- Sponsor
- Instituto Mexicano del Seguro Social
Bacterial Vaginosis, Vaginal Dysbiosis
AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth
Preterm birth is a major cause of mortality and long-term disability. Bacterial vaginosis (BV) is a frequent form of dysbiosis that is often asymptomatic and increases the risk of preterm birth.
- Conditions
- Bacterial Vaginosis, Vaginal Dysbiosis, Premature Delivery
- Trial name
- AUTOP 2 (NCT06349122)
- Testing
- Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone
- Volunteers
- 1,794 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Dysphagia
Standardizing Swallow Pressure Measurements
This study aims to directly compare and contrast swallowing pressure and impedance measurements obtained from two high-resolution manometry (HRM) systems: the Laborie LMT Pharyngeal System and the Medtronic ManoScan ESO HRM…
- Trial name
- NCT07475091
- Testing
- Laborie LMT Pharyngeal System (3.7 mm catheter), Medtronic ManoScan ESO HRM System (4.2 mm catheter)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Vaginal Infection
Multi-Center Study of New Medications to Treat Vaginal Infections
The purpose of this study is to evaluate the safety and efficacy of terconazole gel in the treatment of vaginal infections
- Trial name
- SMART GIVES (NCT02308046)
- Testing
- Terconazole
- Where
- 41 sites in United States
- Volunteers
- 212 people
- Sponsor
- Curatek Pharmaceuticals, LLC
Renal Blood Flow, Anesthesia
MR-Evaluation of Renal Function in Anesthetized Pediatric Patients
The goal of this study is to investigate the effect of the anesthetic agents sevoflurane or propofol on the blood flow and oxygen delivery to the kidneys.
- Conditions
- Renal Blood Flow, Anesthesia, MRI, Renal Oxygenation
- Trial name
- MERAPED (NCT06876870)
- Testing
- Anesthesia Maintenance Agent
- Volunteers
- 50 people
- Sponsor
- Uppsala University
Appendicitis Perforated
Piperacillin/Tazobactam Versus ceftriAxone and Metronidazole for Children With Perforated Appendicitis (ALPACA)
This study is an internal pilot for a multicenter, blinded randomized controlled trial. The purpose of the multicenter trial is to determine whether post-operative piperacillin/tazobactam is more effective than ceftriaxone and…
- Trial name
- ALPACA (NCT05943223)
- Testing
- Piperacillin/tazobactam, Normal saline, CefTRIAXone Injection
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- McMaster Children's Hospital
Acute Appendicitis
Antibiotics vs. Placebo in Acute Uncomplicated Appendicitis
Appendicectomy has been the treatment of acute appendicitis for over a hundred years. Appendicectomy, however, includes operative and postoperative risks despite being a "routine" operation.
- Trial name
- APPACIII (NCT03234296)
- Testing
- Ertapenem
- Where
- Finland
- Volunteers
- 147 people
- Sponsor
- Turku University Hospital
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