Clinical trials: Metronidazole
Periodontitis
Evaluation of L-PRF as an Antibiotic Slow-release Biological Device in the Treatment of Moderate Periodontitis
This study aimed to evaluate the efficacy of leukocyte platelet-rich fibrin (L-PRF) as a local sustained released device for antibiotics.
- Trial name
- NCT06153706
- Testing
- Subgingival application of L-PRF loaded with metronidazole, Subgingival application of L-PRF
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Yasmeen Khaled
Malnutrition Severe, Antibiotic Resistance
First Line Antimicrobials in Children With Complicated Severe Acute Malnutrition
Children with severe malnutrition who are admitted sick to hospitals have a high mortality(death rate), usually because of infection.
- Conditions
- Malnutrition Severe, Antibiotic Resistance, Antibiotic Toxicity
- Trial name
- FLACSAM (NCT03174236)
- Testing
- Ceftriaxone, Benzyl penicillin, Metronidazole
- Where
- 8 sites in Kenya, Uganda
- Volunteers
- 2,000 people
- Sponsor
- University of Oxford
Helicobacter Pylori
Vonoprazan-Based Triple Therapy in Comparison With Extended Sequential Therapy
This study aims to compare the efficacy of the current standard first-line anti-helicobacter pylori regimen, extended proton pump inhibitor-based sequential therapy, with that of vonoprazan-based triple therapy, through a…
- Trial name
- NCT05371249
- Testing
- Vonoprazan-based triple therapy, Extended sequential therapy
- Where
- Taiwan
- Volunteers
- 628 people
- Sponsor
- Fu Jen Catholic University Hospital
H. Pylori Infection
H. Pylori Eradication Using Pyklear in Adults in El Paso, Texas: a Pilot Study
The proposed open-label one arm before-after clinical trial will assess the efficacy of a 14-day quadruple therapy containing 420mg of bismuth subcitrate potassium, 375mg of metronidazole, 375mg of tetracycline hydrochloride…
- Trial name
- NCT01335334
- Testing
- bismuth subcitrate potassium, metronidazole,tetracycline hydrochloride and omeprazole
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Type 2 Diabetes Mellitus (T2DM), Pregnancy
Association Between CGM Metrics in Type 2 Diabetes Pregnancy and Perinatal Morbidity
The purpose of this observational study is to measure the association between continuous glucose monitoring (CGM) parameters and perinatal morbidity in offspring of women with type 2 diabetes.
- Trial name
- PREG CGM (NCT06892314)
- Testing
- Exposure to hyperglycemia (type 2 diabetes)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Sud Francilien
Bacterial Vaginosis
LACTIN-V Study for Recurrent Bacterial Vaginosis
This Phase 2b trial is designed to provide a screening evaluation for the hypothesis that, following a 5-day treatment with MetroGel® to treat BV, L.
- Trial name
- NCT02766023
- Testing
- Lactobacillus crispatus CTV-05, Metronidazole
- Where
- 4 sites in United States
- Volunteers
- 228 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hip Dysplasia, Legg-Calvâe-Perthes Disease
Mixed-Methods Evaluation of Short-, Medium-, and Long-Term Outcomes Following Hip Treatment
This study, titled "Mixed-Methods Evaluation of Short-, Medium-, and Long-Term Outcomes Following Hip Treatment," aims to assess the long-term effectiveness of treatments for pediatric hip conditions, including hip dysplasia…
- Conditions
- Hip Dysplasia, Legg-Calvâe-Perthes Disease, Avascular Necrosis of Hip
- Trial name
- NCT06891196
- Testing
- Long-term Follow-up Surveys
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Coronary Artery Disease, Coronary Stenosis
Transit Time Flow Measurement in Coronary Surgery
Transit-time flowmetry (TTFM) allows grafts quality control during coronary artery bypass surgery by measuring the flow volume through them.
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Coronary Bypass Graft Stenosis
- Trial name
- COLLATERAL (NCT06471062)
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Non-Alcoholic Fatty Liver Disease
Characterization and Technical Evaluation of cT1 for NASH (CATE-NASH)
The primary objective of this study is to evaluate to provide evidence to establish tightly defined cut-offs to identify patients for NASH clinical trial inclusion using cT1 and/or PDFF.
- Trial name
- NCT04341246
- Testing
- LiverMultiscan
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Perspectum
Pelvic Inflammatory Disease
The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID)
This study is a randomized placebo-controlled trial comparing two antibiotic treatment regimens for acute PID. Women with acute PID will be randomized to one of two treatment regimens: 1) a single intramuscular dose of…
- Trial name
- NCT01160640
- Testing
- Ceftriaxone, Doxycycline, Metronidazole
- Where
- 3 sites in United States
- Volunteers
- 233 people
- Sponsor
- Harold Wiesenfeld
Cardiac Arrest, Cardiopulmonary Resuscitation
Generative AI and Gamified Simulation-Based Train-the-Trainer Basic Life Support Training for High School Teachers in Vietnam
The goal of this randomized controlled trial is to learn whether adding generative artificial intelligence (AI) feedback, gamified practice and a structured Train-the-Trainer component to a one-day simulation-based Basic Life…
- Trial name
- NCT07898891
- Testing
- Generative AI and Gamified Simulation-Based Train-the-Trainer BLS Programme, Conventional Instructor-Led Simulation-Based BLS Training
- Where
- 2 sites in Thailand, Vietnam
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Eastern International University
Dysphagia
Standardizing Swallow Pressure Measurements
This study aims to directly compare and contrast swallowing pressure and impedance measurements obtained from two high-resolution manometry (HRM) systems: the Laborie LMT Pharyngeal System and the Medtronic ManoScan ESO HRM…
- Trial name
- NCT07475091
- Testing
- Laborie LMT Pharyngeal System (3.7 mm catheter), Medtronic ManoScan ESO HRM System (4.2 mm catheter)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Male Breast Cancer, Recurrent Breast Cancer
Vaccine Therapy in Treating Patients With Metastatic Breast Cancer
Vaccines may make the body build an immune response to kill tumor cells. This phase I trial is studying the side effects and best dose of vaccine therapy in treating patients with metastatic breast cancer.
- Conditions
- Male Breast Cancer, Recurrent Breast Cancer, Stage IV Breast Cancer
- Trial name
- NCT00071942
- Testing
- recombinant vaccinia-MUC1 vaccine, recombinant vaccinia-TRICOM vaccine, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Cancer Institute (NCI)
Vaginitis
Once Daily In-situ Forming Versus Twice-daily Conventional Metronidazole Vaginal Gels for Treatment of Bacterial Vaginosis
A previous study showed that in situ MTZ vaginal gel twice daily is more effective than the conventional vaginal gel product in sustained cure of BV( 4 weeks after treatment) (80.0% in the in-situ gel group as compared with 47.4…
- Trial name
- MNZ (NCT02365389)
- Testing
- MTZ vaginal gel, Conventional MTZ vaginal gel
- Volunteers
- 64 people
- Sponsor
- Assiut University
Glaucoma, Cataract
IOP and Ocular Biometrics Changes After Phacoemulsification in Glaucoma Patients and Controls
Effect of phacoemulsification on intraocular pressure has been studied with variable results.Furthermore, effect of phacoemulsification on ocular biometrics including anterior chamber depth and angle opening distance has also…
- Trial name
- NCT04334473
- Testing
- phacoemulsification and Intraocular lens implantation, Ultrasound Biomicrosopy (UBM)
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Mai Nasser Abd Elmohsen
Heart Failure
Validation of Ejection Fraction and Cardiac Output Using Biostrap Wristband
In this study, the investigators will compare the accuracy of the Biostrap wristband, a wearable device with a clinical-grade Photoplethysmography (PPG) sensor, to measure ejection fraction and cardiac output in patients…
- Trial name
- NCT05279066
- Testing
- Biostrap Wristband
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Bacterial Vaginosis and Vaginal Candidiasis At Pregnancy
Oral Probiotics for the Treatment and Prevention of Vulvovaginal Infections in Pregnancy - Double-blind, Randomized, Placebo-controlled Study
During pregnancy, bacterial vaginosis (BV), abnormal vaginal flora (AVF) and vulvovaginal candidiasis (VVC) are associated with serious complications and discomfort. Yet, treatment options are limited.
- Trial name
- NCT02795845
- Testing
- Probiotic Capsule containing L. acidophilus, L. Paracasei, L. Rhamnosus, streptococcus thermophilus and Bifidobacterium bifidum
- Where
- 3 sites in Israel
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Adenoma Detection Rate, Colonoscopy
Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study
This is a prospective equivalence colonoscopy study evaluating whether overall adenoma detection rate (ADR) is a reliable alternate for screening ADR.
- Trial name
- NCT05125939
- Testing
- Comparison of ADR
- Where
- 6 sites in United States, Taiwan
- Volunteers
- 2,707 people
- Sponsor
- Evergreen General Hospital, Taiwan
Exercise, Smart Watch
Evaluating the Role of Step Counts in Predicting Readmission and Mortality
This study investigates the relationship between physical activity, heart rate, and sleep quality with recurrent hospitalizations among discharged oncology patients.
- Conditions
- Exercise, Smart Watch, Quality of Life (QOL), Sleep Quality
- Trial name
- STEP-CANCER (NCT06687330)
- Testing
- Tracking Mobility and Health Data with a Smartwatch in Discharged Oncology Patients to Predict Rehospitalization: A Prospective Study
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Gazi University
Dyspepsia
Effect of Triple Versus Quadruple Therapy for Treating Helicobacter Pylori Infection
The Goal of this this clinical trial is to assess and compare the eradication rate of triple and quadruple therapy during treating helicobacter pylori infection among patients presented with dyspepsia.
- Trial name
- NCT07010744
- Testing
- Triple drug regimen, Quadruple therapy
- Where
- Bangladesh
- Volunteers
- 66 people
- Sponsor
- Akil Al Islam
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