Clinical trials: Metronidazole
Clostridium Difficile Infection
A Study of MK-3415, MK-6072, and MK-3415A in Participants Receiving Antibiotic Therapy for Clostridium Difficile Infection (MK-3415A-001)
This study will investigate whether: 1) treatment with MK-3415A in addition to standard of care (SOC) antibiotic therapy will decrease Clostridium difficile infection (CDI) recurrence as compared to treatment with MK-6072 or…
- Trial name
- MODIFY I (NCT01241552)
- Testing
- MK-3415, MK-6072, MK-3415A
- Volunteers
- 1,452 people
- Sponsor
- Merck Sharp & Dohme LLC
Intracranial Pressure, Intracranial Pressure Changes
CoMind Early Feasibility Study
The purpose of this research, which has been determined as non-significant risk by the central IRB overseeing the study, is to obtain information to help further develop a machine (a medical device) to measure the pressure around…
- Conditions
- Intracranial Pressure, Intracranial Pressure Changes, Traumatic Brain Injury, Intracerebral Hemorrhage
- Trial name
- CoMind EFS (NCT06368648)
- Where
- 17 sites in United States
- Volunteers
- 581 people
- Sponsor
- CoMind Technologies Limited
Metastatic Hormone-Sensitive Prostate Cancer
Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer
This study study aims to elucidate the immune responses to a shared antigen vaccine (PROSTVAC) and tumor specific antigens generated DNA vaccine in combination with checkpoint blockade using nivolumab (anti-PD-1), and ipilimumab…
- Trial name
- NCT03532217
- Testing
- PROSTVAC-V, PROSTVAC-F, Nivolumab
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Washington University School of Medicine
Total Knee Arthroplasty, Knee Replacement
Investigating Patient Satisfaction With Smart Knee Implants
The main goal of this study is to see if there is a connection between the social and economic resources available in a patient's neighborhood (measured by the Area Deprivation Index, ADI) and their recovery after knee…
- Conditions
- Total Knee Arthroplasty, Knee Replacement, Knee Replacement Arthroplasty, Knee Osteoarthritis
- Trial name
- NCT06968143
- Testing
- Smart Knee Implant
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Caffeine and Resistance Exercise
Acute Caffeine Intake and Velocity Metrics
The purpose of this study was to determine whether the acute ergogenic effects of caffeine differ according to the velocity metric used to assess strength performance against different relative loads.
- Trial name
- CAF+Vel (NCT07701395)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Chronic Blepharitis
Treatment of Demodex Blepharitis With Ivermectin Gel 0.1% Plus Metronidazole 1%
Blepharitis is a endemic inflammatory disease caused mainly by Demodex folliculorum and Demodex Brevis, This mites are often associated with anaerobic bacteria that produces a skin inflammation, so a intervention that reduces the…
- Trial name
- NCT02236403
- Testing
- Ivermectin 0.1% Metronidazole 1%, None intervention
- Where
- Colombia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Urinary Urge Incontinence
Neuspera Revision Registry - Follow up Revision Experience and Evaluation of Device Outcomes Metrics
Single-arm study where subjects' responses to a questionnaire for the traditional Sacral Neuromodulation (SNM) devices will be compared to the responses regarding the Neuspera SNM System.
- Trial name
- NCT07383688
- Testing
- Neuspera Implantable Sacral Neuromodulation System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Neuspera Medical, Inc.
Congenital Central Hypoventilation Syndrome, Congenital Central Hypoventilation
Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)
Congenital central hypoventilation syndrome (CCHS) is a rare disorder of autonomic and respiratory regulation that frequently alters oxygen delivery to the brain.
- Conditions
- Congenital Central Hypoventilation Syndrome, Congenital Central Hypoventilation, CCHS, CCHS With Hirschsprung Disease
- Trial name
- NCT03568669
- Testing
- NIH Toolbox Cognition Battery
- Where
- 4 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Ilya Khaytin
Cerebral Palsy (CP)
Wearable Eye Tracking During Bimanual Tasks in Children With Cerebral Palsy
This observational pilot study will include 40 children and adolescents aged 6 to 12 years: 20 with cerebral palsy and 20 with typical development.
- Trial name
- NCT07806994
- Testing
- Wearable Eye-Tracking Assessment During Structured Bimanual Tasks
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Orodental Injury
Quantitative Imaging Biomarker Prospective Validation of Dynamic Contrast-enhanced MRI as a Metric of Orodental Injury After Radiotherapy (QI-ProVE-MRI)
This research will focus on the prospective qualification and validation of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) candidate biomarkers (i.e., Ktrans and Ve) to assess the natural history of…
- Trial name
- (QI-ProVE-MRI) (NCT06586892)
- Testing
- Radiotherapy followed by chemotherapy
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- M.D. Anderson Cancer Center
Giardia Lamblia Infection
Anti-protozoal Effect of Steroid Hormone 20-hydroxyecdysone
20-hydroxyecdysone is an ecdysteroid hormone found in invertebrates and plants. 20-hydroxyecdysone exhibits a broad range of biological properties in various in vitro and in vivo models, including anabolic, antioxidant…
- Trial name
- NCT04827537
- Testing
- 20-hydroxyecdysone Oral, Metronidazole Oral
- Where
- Uzbekistan
- Volunteers
- 200 people
- Sponsor
- Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan
Cerebral Palsy, Hemiplegic, Sensory Processing Disorder
Sensory Processing, Postural Stability, and Selective Motor Control in Children With Hemiplegia
The goal of this observational case-control study is to examine the relationship between sensory processing abilities, postural stability, and selective motor control (SMC) in children aged 6-10 years with hemiplegic cerebral…
- Conditions
- Cerebral Palsy, Hemiplegic, Sensory Processing Disorder, Postural Balance, Motor Skills Disorders
- Trial name
- HeSPoM (NCT06989034)
- Testing
- Child Sensory Profile 2 (SP2) for Sensory processing abilities, HUMAC Balance System for Postural stability evaluation, Selective Motor Control Evaluation for the upper and lower extremities
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Effects of the Elements
Efficacy of Diode Laser in Maturogenesis of Immature Teeth With Necrotic Pulps
Recruited patients with immature permanent maxillary anterior teeth with non-vital pulp, and periapical radiolucency, age ranging from 8 to16 years old were randomly allocated into three groups (n=13): Group I, disinfected using…
- Trial name
- NCT05445362
- Testing
- Diode laser disinfection, Diode Laser bio-stimulation., Triple antibiotic paste disinfection
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Reham Hassan
Febrile Neutropenia
ECM and Monitoring w/ Alio Smart Patch in Cancer Pts Receiving Chemotherapy
Undergoing cancer treatment comes with various risks and side effects. This clinical trial aims to reduce those risks and side effects through continuous monitoring of vital signs and blood levels.
- Trial name
- NCT06657183
- Testing
- Alio Smart Patch™
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Case Comprehensive Cancer Center
Labor Pain
Development and Validation of Metrics Lumbar Labor Epidural Catheter Placement
Procedural skills play an important role in anaesthetic expertise. More focused training and assessment of procedural skills will be needed in the future as training moves from an apprenticeship based training system to…
- Trial name
- NCT02179879
- Testing
- Video validation
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- Cork University Hospital
Ulcerative Colitis
Antimicrobial Therapy for Ulcerative Colitis (UC)
The Aim of this randoized controlled pilot study is to find a better treatment strategy for active UC based on the recent knowledge regarding the microbiota in UC and the beneficial or detrimental effects of antibiotics in…
- Trial name
- UC (NCT03986996)
- Testing
- amoxicillin, metronidazole and doxycycline, amoxicillin and doxycyclin
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Wolfson Medical Center
HIV Prevention
In Vivo Drug Interaction Pharmacokinetic Study of Tenofovir 1% Gel and Three Commonly Used Vaginal Products
The purpose of the study is determine if the local release characteristics and systemic exposure to tenofovir (TFV) 1% gel and a given commonly used vaginal product are impacted by concomitant use
- Trial name
- NCT01813162
- Testing
- Tenofovir 1% gel, Vaginal product
- Where
- 2 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- CONRAD
Helicobacter Pylori Infection
Helicobacter Pylori Rescue Treatment in Patients Allergic to Penicillin
The purpose of this study is to assess and compare the effectiveness of furazolidone-tetracycline-containing and metronidazole-tetracycline-containing quadruple regimens for the rescue treatment of Helicobacter pylori infection…
- Trial name
- NCT05135182
- Testing
- Furazolidone, Metronidazole
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Shandong University
Pulp Disease, Dental, Deciduous Teeth
3Mixtatin and MTA Vital Pulpotomy in Primary Molars
The aim of the study is to evaluate clinical and radiographic success of using 3Mixtain versus mineral trioxide aggregate in pulpotomy of deeply carious Primary molars.
- Trial name
- NCT06478940
- Testing
- 3 mixtatin pulpotomy, MTA pulpotomy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Blood Pressure, Hypertension
Onco-primary Care Networking to Support TEAM-based Care
The proposed ONE TEAM Study is an 18-month, cluster randomized controlled trial. This study will use a sequential multiple assignment randomized trial (SMART) design with a second randomization for the intervention group using a…
- Conditions
- Blood Pressure, Hypertension, Cancer, Cancer, Breast
- Trial name
- ONE TEAM (NCT04258813)
- Testing
- iGuide Intervention (Self-guided), iGuide 2 Intervention (Tailored/Targeted), Control
- Where
- United States
- Volunteers
- 313 people
- Sponsor
- Duke University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.