Clinical trials: Metronidazole
Bacterial Vaginosis
Treatment of Bacterial Vaginosis
We are trying to determine if longer duration of therapy with metronidazole or combination therapy of metronidazole plus azithromycin results in better cure rates for BV
- Trial name
- NCT00324818
- Testing
- metronidazole and azithromycin
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus (T1DM)
Clinical Study: Analysis of Glycemic Control and Satisfaction With a Connected Smart Cap in Patients With Type 1 Diabetes Mellitus
This clinical study evaluates the impact of the Cap INSULCLOCK device on glycemic control, treatment adherence, and patient satisfaction in adults with type 1 diabetes mellitus (T1DM).
- Conditions
- Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus (T1DM), Diabetes Management
- Trial name
- CAPSDM1 (NCT06845891)
- Testing
- CONNECTED SMART CAP
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Fernando Sebastián Valles
Colorectal Neoplasms
Trial of Antibiotic Prophylaxis in Elective Laparoscopic Colorectal Surgery: Oral and Systemic Versus Systemic Antibiotics
The purpose of this study is to determine optimal prophylactic antibiotics administration method in elective laparoscopic colorectal surgery.
- Trial name
- NCT00508690
- Testing
- cefmetazole, kanamycin/metronidazole
- Where
- 5 sites in Japan
- Volunteers
- 584 people
- Sponsor
- Japan Multinational Trial Organization
Infection
Preoperative Dose of Co-amoxiclav for Prevention of Postoperative Complications in Dentoalveolar Surgery
There was no evidence to judge the effects of preventative antibiotics for extractions of severely decayed teeth, teeth in diseased gums, or extractions in patients who are sick or have low immunity to infection.
- Trial name
- NCT03844776
- Testing
- Co-Amoxiclav, Paracetamol, Chlorhexidine mouthwash
- Where
- Saudi Arabia
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Taibah University
Pregnancy, Malnutrition in Pregnancy
Nutritional and Anti-infective Interventions for Malnutrition in Pregnancy (Beleuman Welbodi)
Acute malnutrition in pregnancy is a risk factor for adverse outcomes in mothers and their unborn children. Undernutrition during pregnancy can result in maternal complications such as life-threatening hemorrhage and hypertensive…
- Conditions
- Pregnancy, Malnutrition in Pregnancy, Nutrition Disorders, Stunting
- Trial name
- NCT03079388
- Testing
- Ready-to-use-supplementary food, Corn-soy-blend, Monthly intermittent preventive treatment of malaria during pregnancy (IPTp)
- Where
- Sierra Leone
- Volunteers
- 1,489 people
- Sponsor
- Washington University School of Medicine
Bacterial Vaginosis
Safety and Efficacy of Vaginal Microbiota Transplant (VMT) in Women With Bacterial Vaginosis (BV)
The composition of a woman's vaginal microbiota has a significant impact on her reproductive tract health and general quality of life.
- Trial name
- NCT03769688
- Testing
- Cervicovaginal secretions, Metronidazole gel, Screening tests
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
GERD (Gastroesophageal Reflux Disease)
Endoscopic Injection of Autologous Fat-Derived Cells (SVF) for Adults With Refractory Gastroesophageal Reflux Disease (GERD). (The GERD-REVIVE Pilot Study)
The purpose of this pilot clinical study is to evaluate the feasibility and safety of an innovative endoscopic treatment for adults with gastroesophageal reflux disease (GERD) that does not respond adequately to standard…
- Trial name
- GERD-REVIVE (NCT07638423)
- Testing
- Autologous Stromal Vascular Fraction (SVF) Endoscopic Injection
- Volunteers
- 15 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gastrointestinal Hemorrhage
Artificial Intelligent Clinical Decision Support System Simulation Center Study for Technology Acceptance
The purpose of this research study is to measure the effect on of a large language model interface on the usability, attitudes, and provider trust when using a machine learning algorithm-based clinical decision support system in…
- Trial name
- NCT05816473
- Testing
- LLM
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Helicobacter Pylori Infection
Efficacies of Antimicrobial Susceptibility-Guided Versus Empirical Therapy for Rescue Treatment of Helicobacter Pylori Infection
The purpose of this study is to assess efficacy of 14-day antimicrobial susceptibility test guided quadruple therapy for the rescue treatment of Helicobacter pylori infection, then comparing it with 14-day empirical therapy…
- Trial name
- NCT03658746
- Testing
- two sensitive antibiotics(amoxicillin, clarithromycin, metronidazole, tinidazole, levofloxacin, furazolidone and tetracycline), one proton pump inhibitor, colloidal bismuth pectin, two antibiotics based on personal medication history(amoxicillin,levofloxacin, furazolidone)
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Shandong University
Peptic Ulcer
The Pilot Study on Tailored Eradication Therapy According to Clarithromycin Resistance in H.Pylori Patients
This study assessed the effect of tailored eradication therapy according to Clarithromycin resistance in Helicobacter pylori patients.
- Trial name
- NCT02648659
- Testing
- Ilaprazole, Amoxicillin, Clarithromycin
- Volunteers
- 50 people
- Sponsor
- Kyungpook National University Hospital
Lymphoma
Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach
RATIONALE: Antibiotic therapy and antacids are used to treat Helicobacter pylori infection of the stomach. These treatments may also have an effect on gastric MALT lymphoma of the stomach.
- Trial name
- NCT00002682
- Testing
- Amoxicillin, Bismuth Subsalicylate, Clarithromycin
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- M.D. Anderson Cancer Center
H. Pylori Infection
Eradication of H. Pylori Therapy Individualized by the Mutation of 23S rRNA of H. Pylori
Patients infected with H. pylori are treated with the individualized regimen which is based on the mutation of 23S rRNA of H. pylori.
- Trial name
- EHR (NCT02761005)
- Testing
- Eradication of H. pylori
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Hamamatsu University
Surgical Education
Testing the Efficacy of an Artificial Intelligence Real-Time Coaching SystemSystemSimulatioTraining of Medical Students
Background: Trainees learn surgical technical skills through apprenticeship model working closely with surgeons and given increased responsibility in patient cases under expert supervision.
- Trial name
- NCT05168150
- Testing
- Experimental: Experimental Group - Intelligent Continuous Expertise Monitoring System group, Experimental Group In-person expert-mediated instruction group
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- McGill University
Unexplained Infertility, Endometriosis
Probiotic and Antibiotic Therapies in Women With Unexplained Infertility
The study is designed as a proof of concept pilot study with 3 study arms to evaluate the safety and feasibility of the use of oral probiotics and/or antibiotics in women with unexplained infertility/endometriosis.
- Trial name
- NCT04955574
- Testing
- SH-DS01 + Metronidazole
- Sponsor
- McMaster University
Blood Pressure, Hypertension
Onco-primary Care Networking to Support TEAM-based Care
The proposed ONE TEAM Study is an 18-month, cluster randomized controlled trial. This study will use a sequential multiple assignment randomized trial (SMART) design with a second randomization for the intervention group using a…
- Conditions
- Blood Pressure, Hypertension, Cancer, Cancer, Breast
- Trial name
- ONE TEAM (NCT04258813)
- Testing
- iGuide Intervention (Self-guided), iGuide 2 Intervention (Tailored/Targeted), Control
- Where
- United States
- Volunteers
- 313 people
- Sponsor
- Duke University
Covid19, Appendicitis
Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients
This study evaluates operative and non-operative management of acute appendicitis (infection or inflammation of the appendix) and acute cholecystitis (inflammation/infection of the gallbladder) in patients with active mild to…
- Conditions
- Covid19, Appendicitis, Cholecystitis, Acute, Cholecystitis; Gallstone
- Trial name
- NCT04748120
- Testing
- Operative management, Non-operative management
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Mild Cognitive Impairment, Dementia, Mild
Precision Medicine Approach for Early Dementia & Mild Cognitive Impairment
The goal of this clinical trial is to compare a precision medicine approach to the standard-of-care for people with mild cognitive impairment or early-stage dementia.
- Trial name
- EVANTHEA (NCT05894954)
- Testing
- Precision Medicine Approach, Hormones and Medications tailored to lab tests, combined with devices that support stress management and brain exercises, Standard-of-Care
- Where
- 6 sites in United States
- Volunteers
- 73 people
- Sponsor
- Alzheimer's Prevention and Reversal Project, Inc.
Nutrition
Gut Flora Dependent Metabolism of Dietary Phosphatidylcholine and Cardiovascular Disease
The purpose of this study is to see if intestinal bacteria plays a role in choline metabolism (a form of choline monitored in this study is called phosphatidylcholine, also known as lecithin).
- Trial name
- Glory (NCT01519310)
- Testing
- Antibiotic (metronidazole and ciprofloxacin)/probiotic
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Helicobacter Pylori Treatment Failure
High Dose Amoxicillin Versus Tetracycline as Second-line Treatment of Resistant Helicobacter Pylori Infection
No trial has examined the the efficacy of high dose amoxicillin based quadruple therapy as second-line treatment for Helicobacter pylori infection.
- Trial name
- NCT02175927
- Testing
- Lansoprazole, Bismuth Potassium Citrate, Metronidazole
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Clostridium Enterocolitis, Pseudomembranous Colitis
Response of Clostridium Difficile Infection to Metronidazole Therapy
In this record review study, our objective is to determine the rates of cure, failure and relapse following treatment of C. difficile colitis with metronidazole.
- Conditions
- Clostridium Enterocolitis, Pseudomembranous Colitis, Antibiotic-Associated Colitis
- Trial name
- NCT00304369
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Michael E. DeBakey VA Medical Center
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