Clinical trials: Metronidazole
Periodontitis, Periodontal Diseases
Microbial Associations in Periodontal Health and Disease
The purpose of this study is to determine the clinical and microbiological effects of systemically administered metronidazole alone or in combination with professional plaque removal on periodontally diseased patients.
- Trial name
- NCT00066001
- Testing
- metronidazole
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- The Forsyth Institute
Periapical Lesion, Periapical Periodontitis
Comparing Two Medicines for Healing Jaw Bone Infections After Root Canal Treatment
This study compares two commonly used intracanal medicaments-Triple Antibiotic Paste and Calcium Hydroxide-in patients with infected single-rooted teeth.
- Trial name
- NCT07239739
- Testing
- Triple Antibiotic Paste, Calcium Hydroxide (Ca(OH)2)
- Volunteers
- 62 people
- Sponsor
- Faiz ur rahman
Prevention of Surgical Site Infections
Tumescent Antibiotic Delivery Pharmacokinetics
Tumescent Antibiotic Delivery (TAD) is a technique for improving the prevention of surgical site infections (SSI). TAD involves the subcutaneous infiltration of tumescent local anesthesia (TLA) containing water soluble…
- Trial name
- NCT01046981
- Testing
- Tumescent Antibiotic Delivery of cefazolin with or without metronidazole, Intravenous Antibiotic Delivery
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Klein, Jeffrey A., M.D.
Type 1 Diabetes
The Association Between Time in Range With Markers of Endothelial and Cardiovascular Function
In this observaltional study, 90 patients aged >12 years old with T1DM who are on MiniMed 780G system will be included.We aim to investigate the association between time in range (70-140mg/dl) and time in tight range…
- Trial name
- NCT06810700
- Testing
- MiniMed 780G
- Volunteers
- 90 people
- Sponsor
- Attikon Hospital
Neuroma Amputation
Evaluation of Ultrasonic Neuroma Size With Residual Limb Pain in Above-Knee Amputees
Background: The formation of neuromas, a fusiform swelling of a nerve or nerve ending, is a well documented response to limb amputation.
- Trial name
- NCT00686764
- Testing
- Observational
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Exercise, Smart Watch
Evaluating the Role of Step Counts in Predicting Readmission and Mortality
This study investigates the relationship between physical activity, heart rate, and sleep quality with recurrent hospitalizations among discharged oncology patients.
- Conditions
- Exercise, Smart Watch, Quality of Life (QOL), Sleep Quality
- Trial name
- STEP-CANCER (NCT06687330)
- Testing
- Tracking Mobility and Health Data with a Smartwatch in Discharged Oncology Patients to Predict Rehospitalization: A Prospective Study
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Gazi University
Ulcerative Colitis
Parasitic Infections and Ulcerative Colitis: Combining Anti-parasitic and Immunomodulatory Treatments May Achieve Remission
The study aimed to explore the link between parasitic infections and the severity of ulcerative colitis (UC). 120 UC patients were divided into three groups: those without infection, those with Giardia lamblia infection treated…
- Trial name
- NCT06583863
- Testing
- Echinacea Extract, MetroNIDAZOLE 500 MG Oral Tablet [Flagyl]
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Benha University
Ketogenic Diet, Weight Loss
Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.
This project will be a three-group controlled 6-wk feeding study where all meals are prepared and provided to obese participants. All participants will be fed a 25% energy-restricted diet.
- Trial name
- STAK (NCT06449287)
- Testing
- Diet, Blood Draw, Ketone/Glucose Monitoring
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Resilience, Psychological, Mental Well-being
Evaluating a Digital Intervention to Improve Resilience and Reduce Stress in Stanford Populations
High-achieving academic and entrepreneurial populations face elevated risks of chronic stress, anxiety, and burnout. These populations often underutilize mental health services due to stigma, time constraints, or accessibility…
- Trial name
- SIER-WONE (NCT07565571)
- Testing
- Intervention WONE App (full Version)
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Stanford University
Rosacea
A Phase II, Randomized Study of ACZONE™ (Dapsone) Gel, 5% for Papulopustular Rosacea.
The purpose of this study is to evaluate the safety and effectiveness of ACZONE™ gel compared to placebo (inactive substance), MetroGel® and a combination of ACZONE™ gel and MetroGel® for the treatment of rosacea.
- Trial name
- NCT00249782
- Testing
- Vehicle control, 2x/day, ACZONE (dapsone) Gel, 5%, 2x/day, ACZONE (dapsone) Gel, 5%, 1x/day
- Where
- 26 sites in United States
- Volunteers
- 400 people
- Sponsor
- Allergan
Dural Arteriovenous Fistula, Glymphatic System
NAIF 2.0 - COGNIFY
The goal of this observational study is to learn whether intracranial dural arteriovenous fistulae, abnormal connections between arteries and veins in the covering of the brain, may affect a brain's waste-clearance system, known…
- Trial name
- NAIF 2 (NCT07824297)
- Testing
- Brain MRI
- Where
- 3 sites in Italy, Spain and 1 more
- Volunteers
- 20 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Glaucoma, Cataract
IOP and Ocular Biometrics Changes After Phacoemulsification in Glaucoma Patients and Controls
Effect of phacoemulsification on intraocular pressure has been studied with variable results.Furthermore, effect of phacoemulsification on ocular biometrics including anterior chamber depth and angle opening distance has also…
- Trial name
- NCT04334473
- Testing
- phacoemulsification and Intraocular lens implantation, Ultrasound Biomicrosopy (UBM)
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Mai Nasser Abd Elmohsen
Bacterial Vaginosis, Bacterial Vaginitis
Supplementation of Standard Antibiotic Therapy With Oral Probiotics for Bacterial Vaginosis
The purpose of this study was to determine whether supplementation of standard antibiotic therapy with oral probiotic preparation prOVag containing lactic acid bacteria influences recurrence of bacterial vaginosis/vaginitis.
- Trial name
- NCT01993524
- Testing
- probiotic
- Volunteers
- 594 people
- Sponsor
- IBSS Biomed S.A.
Helicobacter Pylori Infection
Comparison of Two Novel First-line Anti-Helicobacter Pylori Therapy
The Asian-Pacific Consensus Report has recommended that proton pump inhibitor (PPI)-clarithromycin-amoxicillin or metronidazole treatment for 7 to14 days is the first choice treatment for H pylori infection.
- Trial name
- NCT03383003
- Testing
- Nexium, Amolin, Klaricid
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- Chang Gung Memorial Hospital
Insomnia Chronic
Prospective Observational Study on the Effectiveness of Daridorexant in Chronic Insomnia in a Real-World Setting
The primary objectives of this study is to evaluate the real-world effectiveness of daridorexant 50 mg in improving both subjective (self-report) and objective (actigraphic) sleep parameters in patients with chronic insomnia.
- Trial name
- NCT07132086
- Testing
- Daridorexant 50 mg orally, once daily at bedtime, administered as monotherapy or add-on therapy for chronic insomnia, in a real-world, observational, prospective clinical setting
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Pulmonary Disease, Chronic Obstructive
Digihaler in Chronic Obstructive Pulmonary Disease (COPD)
This is a multi-center 3-month study to determine the variation in ProAir Digihaler metrics [peak inspiratory flow (PIF), inhalation volume, number of inhalation events] amongst COPD patients in the ambulatory setting.
- Trial name
- NCT05241288
- Testing
- Albuterol eMDPI DS
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- University of North Carolina, Chapel Hill
Sroke Patients
Balance Training Using Artificial Intelligence on Pelvic Asymmetry in Stroke Patients.
After stroke, hemiplegia is one of the most prevalent impairments. It has an extensive effect on altering balance and gait performance.
- Trial name
- NCT07357896
- Testing
- balance training using artificial intelligence, conventional balance training
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Cairo University
Helicobacter Pylori Infection, Dysbiosis
The Efficacy of 10-day and 14-day Bismuth-based Quadruple Therapy in First-line H. Pylori Eradication
Helicobacter pylori (H. pylori) infection is the major cause of gastritis, peptic ulcer disease, and gastric cancer in adults. Bismuth-based quadruple therapy is recommended by a recent review to be the first-line treatment for…
- Conditions
- Helicobacter Pylori Infection, Dysbiosis, Probiotics
- Trial name
- Bsm10 (NCT04527055)
- Testing
- Bismuth Subcitrate 120 MG Oral Tablet, Lactobacillus acidophilus and Bifidobacterium lactis Bb12, Esomeprazole 40mg
- Where
- Taiwan
- Volunteers
- 312 people
- Sponsor
- National Cheng-Kung University Hospital
Peri-Implantitis, Implant Complication
"Surgical Vs. Non-surgical Peri-implant Therapy"
The aim of this randomized clinical trial is to evaluate the effectiveness, in terms of clinical and radiographic changes, of non-surgical peri-implant therapy (mechanical/chemical) versus regenerative surgical therapy (xenograft…
- Conditions
- Peri-Implantitis, Implant Complication, Bone Loss
- Trial name
- NCT05168891
- Testing
- Surgical therapy, Non-surgical therapy of peri-implantitis
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Mental Health, Mental Disorders
Personalized, Transdiagnostic Approach to Preventative Mental Health
This study is investigating the self-report adherence and assessment completion rates when presented with a transdiagnostic, partial assessment multiple times a day when compared with a monotopic, complete assessment once a day.
- Conditions
- Mental Health, Mental Disorders, Delivery of Health Care, Self-Assessment
- Trial name
- NCT03946319
- Testing
- Introspect Health
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Introspect Health
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