Clinical trials: Misoprostol
Cesarean Section Complications, Blood Loss, Surgical
Tranexamic Acid Versus Misoprostol in Reducing Blood Loss in Cesarean Section in Primigravida
The aim of the work is to compare the efficacy of preoperative IV tranexamic acid and rectal misoprostol in reducing blood loss in the elective cesarean section.
- Conditions
- Cesarean Section Complications, Blood Loss, Surgical, Misoprostol, Tranexamic Acid
- Trial name
- NCT04635007
- Testing
- Tranexamic acid, Misoprostol 200mcg Tab
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Cervical Ripening
Intravaginal Misoprostol Versus Dinoprostone Before Diagnostik Hysteroscopy
Comparison of intravaginal misoprostol and dinoprostol for the purpose of cervical ripening before diagnostic hysteroscopy in the women at the reproductive age:RANDOMİSED,CONTROLLED PROSPECTİVE TRİAL Objective.
- Trial name
- NCT01620814
- Testing
- Dinoprostone, misoprostol, control
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Post Partum Hemorrhage
Sublingual Misoprostol in Reduction of Caesarean Blood Loss
Caesarean delivery is inevitably associated with a higher amount of blood loss vis-à-vis primary postpartum haemorrhage, when compared to vaginal delivery.
- Trial name
- SUMIROCBLOL (NCT05532215)
- Testing
- Misoprostol, Oxytocin
- Where
- Nigeria
- Volunteers
- 152 people
- Sponsor
- OZORI EBIOGBO STANLEY
Second Trimester Abortion
Mifepristone and Misoprostol Compared With Misoprostol Alone for Second Trimester Abortion
Mifepristone and Misoprostol Compared With Misoprostol Alone for Second Trimester Abortion - a Double Blinded Randomized Controlled Trial
- Trial name
- NCT03044093
- Testing
- Mifepristone, Misoprostol
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14-21 Weeks LMP)
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00957346
- Testing
- Mifepristone+misoprostol
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Miscarriage
Sublingual Versus Vaginal Misoprostol In Medical Treatment of Second Trimestric Missed Miscarriage
The aim of this work is to compare the effectiveness of vaginal versus sub-lingual misoprostol for medical treatment of the second trimester missed miscarriage
- Trial name
- NCT05088707
- Testing
- sublingual misoprostol, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Missed Abortion, Pregnancy
Mifepristone and Misoprostol Versus Misoprostol Alone for Missed Abortion: A Randomized-controlled Trial
The purpose of the proposed study is to compare - in a randomized, placebo-controlled, double-blinded trial - a combination of mifepristone and misoprostol to misoprostol used alone for missed abortion.
- Trial name
- NCT02342002
- Testing
- Mifepristone, Misoprostol
- Where
- 4 sites in Argentina, Gabon and 2 more
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Labour Induction
Vaginally Administered Versus Per Oral Misoprostol in Induction of Labour
The purpose of this study is to investigate the effectiveness and safety of vaginally administered misoprostol (Misodel) versus per orally administered misoprostol (Cytotec) in induction of labour in nulliparous women.
- Trial name
- NCT02539199
- Testing
- Misoprostol, modified-release pessary, Misoprostol, per-oral tablets
- Where
- 5 sites in Finland
- Volunteers
- 270 people
- Sponsor
- Tampere University Hospital
Second Trimester Abortion
Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion
the investigators aimed to study the efficacy and safety of nitric oxide donors when combined with prostaglandins in induction of second trimester abortion expecting that both drugs when used together will be of greater…
- Trial name
- NCT03407521
- Testing
- Misoprostol, isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Primiparous Women
Combined Misoprostol and Cervical Balloon vs Misoprostol Alone for Induction on the First Day in Primiparas
Misoprostol (a prostaglandin E1 analog) is commonly used for cervical ripening and labor induction via vaginal administration. The cervical balloon is another commonly used method that provides mechanical cervical dilation.
- Trial name
- NCT07690007
- Testing
- Misoprostol, Misoprostol plus Cervical Balloon
- Volunteers
- 220 people
- Sponsor
- Peking University First Hospital
Abortion in Second Trimester
Assessing Outpatient 'Day Procedure' for Second-trimester Medical Abortion at Two Public Sector Hospitals in Nepal
This study seeks to evaluate the safety, acceptability and feasibility of an outpatient "day procedure" for medical abortion at 13-18 weeks gestation in two public sector facilities.
- Trial name
- NCT05046041
- Testing
- Mifepristone + Misoprostol
- Where
- 2 sites in Nepal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Failed Induction of Labor
A Novel Protocol for Labour Induction
The use of foley catheter was tested many times and proved to be effective for induction of labour.
- Trial name
- NCT01506388
- Testing
- foley catheter, Misoprostol, Vaginal IMN
- Where
- 2 sites in Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endometrial Polyps in Infertile Patients
Misoprostol as a Treatment for Endometrial Polyps in Infertile Patients
Endometrial polyps are one of the main causes of infertility in women. In this work we propose an alternative, effective, economical and safe treatment: the use of misoprostol
- Trial name
- NCT04270994
- Testing
- Misoprostol
- Volunteers
- 54 people
- Sponsor
- Henry Aristoteles Mate-Sánez
Labor Induction
Oral Misoprostol for Outpatient Induction of Labor
An increasing proportion of pregnant women have their labors induced due to changing guidelines. In correlation with this increase, the population of the induced women has changed toward more women with a low-risk pregnancy.
- Trial name
- NCT04596397
- Testing
- Inpatient setting, Outpatient setting
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Sorlandet Hospital HF
Pregnancy
A Randomized Comparison of Transcervical Foley Bulb With Vaginal Misoprostol to Vaginal Misoprostol Alone for Induction of Labor
A randomized, prospective trial will be offered to women admitted to the Roosevelt Hospital labor floor for labor induction. The hypothesis is that the simultaneous use of a foley bulb together with vaginal misoprostol will…
- Trial name
- NCT02566005
- Testing
- misoprostol, Foley bulb
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Cervical Ripening
Cervical Ripening Balloon Compared With Vaginal Misoprostol for Cervical Ripening in Obese Woman at Term
Cervical ripening balloon compared with vaginal misoprostol for cervical ripening in obese woman at term
- Trial name
- NCT07685756
- Testing
- Cervical folleys, Misoprostol
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- HUDDA Ahmad
Abortion, Second Trimester
Induction of Abortion in the Second Trimester
To compare between the effects of misoprostol with hyoscine N-butyl bromide and misoprostol alone on shortening the time of abortion induction in the second trimester.
- Trial name
- NCT06207539
- Testing
- hyoscine N-butyl bromide under the generic name of buscopan ampoule produced by Sanofi company, misoprostol under the generic name of misotac tablets
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Pregnancies of Unknown Location (PUL)
A Prospective Study of Misoprostol Administration in Asymptomatic Patients With Pregnancies of Unknown Location
A randomized prospective double blind study of misoprostol administration in asymptomatic patients with pregnancies of unknown location.
- Trial name
- amalis (NCT02581761)
- Testing
- CYTOTEC
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Labour,Induced
Oral Misoprostol Solution in Labor Induction
This study compares safety and efficacy between repetitive hourly dose of oral misoprostol and two hourly dose oral regimens for cervical ripening and labor induction.
- Trial name
- NCT03927807
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pregnancy
Simplified Medical Abortion in Rural India
It is estimated that around 50 000 women die every year due to consequences of unsafe abortion (Singh et al, 2009). A majority of these deaths occur in low-income countries where access to safe abortion care is limited.
- Trial name
- NCT01827995
- Testing
- Self assessment, Routine assessment
- Where
- India
- Volunteers
- 731 people
- Sponsor
- Karolinska Institutet