Clinical trials: Morphine, completed
Pain, Postoperative
Preventive Skin Analgesia With Lidocaine Patch 5% for Controlling Post-thoracotomy Pain
Thoracotomy is one of the most painful surgical incision. Uncontrolled acute post-thoracotomy pain reducing deep breathing exercises and secretion clearance increased the incidence of postoperative pulmonary complications…
- Trial name
- NCT02751619
- Testing
- Lidocaine patch 5%
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Radiculopathy, Sciatica
Pain Treatment for Sciatica
This study will test the effectiveness of two drugs-nortriptyline and MS Contin (a type of morphine)-to treat pain caused by lumbar radiculopathy, or sciatica.
- Trial name
- NCT00009672
- Testing
- Nortriptyline, Morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Malaria
Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra
Artemisinin-based combination therapy (ACT) has been known to be controversial for stopping malaria transmission. The addition of primaquine (PQ) - the only drug commercially available that kills mature transmission stage - to…
- Trial name
- NCT01389557
- Testing
- Dihydroartemisinin-piperaquine with primaquine
- Where
- Indonesia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cancer
E-MOSAIC Electronic Tool to Monitor Symptoms
RATIONALE: A hand held electronic tool used to monitor symptoms and assess quality of life may improve communication between patients and their doctors and improve the ability to plan treatment for patients with advanced cancer…
- Trial name
- NCT00477919
- Where
- 7 sites in Switzerland
- Volunteers
- 264 people
- Sponsor
- Swiss Cancer Institute
Pain
Safety Study of Intravenous Hydromorphone Using Incremental 1mg Doses up to 2mg for Adult ED Patients
We wish to examine the safety and speed of onset of giving a dose of 1mg hydromorphone followed by an additional 1mg. Eligible patients will be given 1 mg intravenous (IV) hydromorphone.
- Trial name
- NCT00682435
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Montefiore Medical Center
Postoperative Pain Management in Video-Assisted Thoracoscopic Surgery
Intrathecal Morphine for Recovery and Outcomes After VATS
This study will compare two different methods of pain management in patients undergoing video-assisted thoracoscopic surgery (VATS).
- Trial name
- IMPROVE-VATS (NCT07231926)
- Testing
- Intrathecal Morphine, Serratus Anterior Plane Block (SAPB) group, Dexmedetomidine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Cesarean Section Complications, Spinal Anesthesia
Phenylephrine Versus Norepinephrine for Maintenance of Hemodynamic During Cesarean Section Under Spinal Anesthesia
Comparison between prophylactic continuous variable infusion of phenylephrine (starting dose 0,5mcg/kg/min) and norepinephrine tartrate (starting dose 0,1mcg/kg/min) to prevent hypotension and maintain cardiac output under spinal…
- Trial name
- PHENAD (NCT03849508)
- Testing
- Norepinephrine, Phenylephrine
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Pain, Postoperative
Transversus Abdominis Plane Block and Quadratus Lumborum Block in Pediatric Patients
In the pediatric age group, postoperative pain is very important for the children to have a comfortable and problem-free postoperative period.
- Trial name
- NCT04209478
- Testing
- Tramadol hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Gene, Polymorphosis
Gene Polymorphisms and Morphine Analgesic Consumption
Variation of morphine requirements are seen considerably. Studies showed that pharmacogenetics (PGx) could possibly be used to tailor pain medication according to an individual's genetic background.
- Trial name
- NCT04621864
- Where
- Qatar
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Cancer Pain
An Observation Study to Assess the Efficacy and Safety of Proportional Doses of Painkyl® in Patients With Breakthrough Cancer Pain
An open-label, single arm, observation study, to assess the efficacy and safety of proportional doses of Painkyl® in patients with breakthrough cancer pain.
- Trial name
- NCT05209906
- Testing
- Fentanyl Buccal Soluble Film
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- Mackay Memorial Hospital
Postdural Puncture Headache, Post-Lumbar Puncture Headache
Incidence of Headache Following an Unintentional Dural Puncture
The purpose of this study is to evaluate the use of intrathecal morphine administration following an unintentional dural puncture, to decrease the incidence of post dural puncture headaches (PDPH) in obstetric patients.
- Conditions
- Postdural Puncture Headache, Post-Lumbar Puncture Headache, Cerebrospinal Fluid Leaks
- Trial name
- NCT01977898
- Testing
- Morphine, Saline
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Epidural Analgesia, Obstetric
Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean Delivery
To evaluate the levels of morphine in a patient's blood when morphine is given into the epidural space in the form of DepoDur® either alone or following a dose of lidocaine also given in the epidural space.
- Trial name
- NCT00804609
- Testing
- DepoDur following epidural lidocaine, DepoDur following spinal anesthetic
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Motivation, Drug Effect
How Stress Alters Opioid Drug Effects
The main objective of the study is to test the hypothesis that opioid drug effects vary as a function of pre-drug affective state.
- Conditions
- Motivation, Drug Effect, Stress Reaction, Misuse, Opioid
- Trial name
- OPIOIDREWARD (NCT06485817)
- Testing
- Oxycodone, Stress State Induction, Control State Induction
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Analgesia
Intra-Articular Morphine Versus Bupivacaine on Knee Motion in Patients With Osteoarthritis
CONTEXT AND OBJECTIVE: Osteoarthritis causes pain and disability in a high percentage of elderly people. The aim of the present study was to compare the analgesic effect of intra-articular bupivacaine and morphine in patients…
- Trial name
- NCT00636415
- Testing
- morphine
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Bladder Cancer
The Impact of Intrathecal Morphine Versus Continuous Epidural Analgesia on Return of Bowel Function in Patients Undergoing Laparoscopic Ileal Conduit
This study aims to compare the effects of intrathecal morphine (ITM) and continuous epidural analgesia (CEA) on bowel function recovery after Bricker surgery.This study was a prospective, randomized controlled trial that included…
- Trial name
- NCT06688643
- Testing
- ITM group, EA group
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Xiaguang Duan
Sickle Cell Crisis
Ketamine for Acute Painful Crisis in Sickle Cell Disease Patients
Investigators hypothesize that administration of ketamine for pain relief in sickle cell patients with vaso-occlusive crisis early on will lead to a more rapid improvement in pain score and less narcotic requirement.
- Trial name
- NCT03431285
- Testing
- Morphine Group, Ketamine Group, standard IV hydration
- Where
- Saudi Arabia
- Volunteers
- 278 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Gynecological Cancer Surgery, Regional Anesthesia Morbidity
The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia
The aim of this study is to compare the effectiveness of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia in gynecological cancer surgeries.
- Trial name
- NCT06382376
- Testing
- Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Cesarean Section, Intrathecal Morphine
The Contribution of Intrathecal Morphine Administration to Postoperative Patient Satisfaction During Cesarean Delivery
Evaluating the contribution of intrathecal morphine administration to postoperative patient satisfaction during cesarean delivery with the QoR-40 (Quality of Recovery 40) patient satisfaction compilation quality scale, scored…
- Conditions
- Cesarean Section, Intrathecal Morphine, Quality of Recovery 40
- Trial name
- ITM (NCT06076018)
- Testing
- Group morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Neuroblastoma Recurrent
CH14.18 1021 Antibody and IL2 After Haplo SCT in Children With Relapsed Neuroblastoma
A six courses regimen consisting of a 8 hour infusion (ch14.18/CHOmAb 20 mg/m²) for five consecutive days will be administered every 4 weeks, starting 60-180 days after previous haploidentical stem cell transplantation.
- Trial name
- NCT02258815
- Testing
- ch14.18/CHO
- Where
- 4 sites in Austria, Germany
- Volunteers
- 35 people
- Sponsor
- University Children's Hospital Tuebingen
Opiate Dependent
Morphine Slow-release Capsules in Substitution Therapy
To compare the effectiveness of slow release oral morphine treatment in patients that previously have been treated with methadone
- Trial name
- NCT01079117
- Testing
- Sevre-Long™, Slow release oral morphine, Methadone
- Where
- Switzerland
- Volunteers
- 276 people
- Sponsor
- Mundipharma Medical Company
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