Clinical trials: Morphine, completed
Elderly, Surgery
Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium
Delirium is a frequently occurred cerebral complication in elderly patients after surgery, and its occurrence is associated with worse outcomes.
- Conditions
- Elderly, Surgery, Analgesia, Dexmedetomidine
- Trial name
- NCT03012984
- Testing
- Dexmedetomidine supplemented morphine analgesia, Morphine analgesia
- Where
- 12 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Peking University First Hospital
Cancer-related Problem/Condition
Magnesium Associated With Morphine for Cancer Pain Relief
This study is an evaluation of the analgesic effect of magnesium associated with morphine in patients with cancer pain.
- Trial name
- NCT01541111
- Testing
- Magnesiun
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Renal Colic
Combination Trial of Intravenous Paracetamol - Morphine for Treating Acute Renal Colic in Emergency Setting: An Optimum Treatment
This randomized, placebo-controlled trial evaluated the analgesic efficacy and safety of intravenous morphine-paracetamol combination and morphine-dexketoprofen combination morphine for the optimum treatment of renal colic.
- Trial name
- NCT03865004
- Testing
- Paracetamol+Morphine, Dexketoprofen plus Morphine
- Volunteers
- 136 people
- Sponsor
- Akdeniz University
Dry Eye, Sjogren's Syndrome
Pilot Study for Testing Safety of Repetitive Magnetic Stimulation for Treatment of Dry Eye
The study aims to test the safety of Repetitive Magnetic Stimulation (RMS) treatment for dry eye disease. Patients are asked to undergo a one-time treatment with Epitech Ocular Magnetic Stimulation Device on one eye in the first…
- Conditions
- Dry Eye, Sjogren's Syndrome, Aqueous Tear Deficiency, Meibomian Gland Dysfunction
- Trial name
- NCT03012698
- Testing
- Ocular Repetitive Magnetic Stimulation (RMS) treatment
- Where
- 3 sites in Israel
- Volunteers
- 29 people
- Sponsor
- Epitech Mag Ltd.
Low Back Pain, Acute
Interfascial Infiltration for Acute Unspecific Low Back Pain in the Emergency Department
Pain relief and functional impairment have been shown to remain poor to moderate over weeks after emergency department discharge, in patients who seek ED management for acute nontraumatic, nonradicular low back pain.
- Trial name
- PreSosLumbago (NCT03968185)
- Testing
- Interfascial infiltration, Standard medical treatment
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Analgesia, Analgesics, Opioid
Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study
The proposed pilot study is a prospective, randomized, controlled, double-blind, single-center pilot study.The aim of this pilot project is to evaluate the feasibility of a phase III study on the use of dexmedetomidine in…
- Conditions
- Analgesia, Analgesics, Opioid, Anesthesia, Obstetrical, Anesthesia, Spinal
- Trial name
- NCT05099055
- Testing
- Dexmedetomidine 0.004 MG/ML [Precedex], Opioids
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- St. Justine's Hospital
Substance-Related Disorders, Depressive Disorder
Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders
Adolescent substance abuse results in significant negative outcomes and extraordinary costs for youths, their families, communities, and society.
- Conditions
- Substance-Related Disorders, Depressive Disorder, Anxiety Disorder
- Trial name
- NCT00438685
- Testing
- Outpatient MST/OPTION-A, Usual Services
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Postoperative Pain
Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section
The cesarean section is one of the most commonly performed surgeries in the world and it represents 20% of the births in France. Postoperative pain is moderate-to-severe during the first 48 hours after this procedure.
- Trial name
- ROMANCE (NCT02410317)
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Grenoble
Colorectal Cancer, Anesthesia
Effects of Dexmedetomidine/Lidocaine/Intrathecal Morphine on Cancer Metastasis Biomarker After Colorectal Surgery
This is a prospective randomized controlled trial. Investigators aimed to compare the effect of three different anesthetic adjuvants (continuous infusion of lidocaine or dexmedetomidine, intrathecal morphine injection) on the…
- Conditions
- Colorectal Cancer, Anesthesia, Cancer Metastatic, Inflammation
- Trial name
- NCT05742438
- Testing
- Lidocaine IV, Dexmedetomidine IV, intrathecal morphine
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Samsung Medical Center
Opioid Use
Two Approaches of Transversus Abdominis Block (TAP ) in Laparoscopic Cholecystectomy
the investigators will compare the effect of pre-operative oblique subcostal TAP and lateral TAP blocks on the total perioperative opioids consumption for patients undergoing elective laparoscopic cholecystectomy
- Trial name
- TAP (NCT05946733)
- Testing
- Group A, Group B, Group C
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Acute Pain, Chronic Pain
The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:
Single-center study in order to assess whether the tap block can make extremely beneficial in terms of reducing the acute and chronic pain as well as for use of opioids and side effects related to it in patients undergoing…
- Trial name
- NCT02460640
- Testing
- Tap block, intravenous Patient controlled analgesia, Morphine
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- Regina Elena Cancer Institute
Otitis Media
Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing Myringotomy
The purpose of this study is to compare the difference in effect of three clinically common methods of providing pain medication during surgery for ventilating tubes placed for recurring ear infections.The methods are fentanyl…
- Trial name
- NCT01244126
- Testing
- Intranasal fentanyl, morphine IM, IV morphine
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Baylor College of Medicine
Pain, Postoperative
Methadone for Postoperative Pain
The aim of this study is to compare the efficacy of methadone versus morphine in dealing with postoperative pain, in laparoscopic cholecystectomy under total intravenous anesthesia (TIVA); Efficacy is defined in terms of the…
- Trial name
- NCT01833715
- Testing
- Morphine, Methadone, TIVA
- Where
- Chile
- Volunteers
- 86 people
- Sponsor
- Universidad de Valparaiso
Colorectal Cancer
Assessing Safety of NIPOX in Peritoneal Carcinomatosis of CRC
This study determine the maximal tolerate dose
- Trial name
- NIPOX (NCT03253133)
- Testing
- Oxaliplatin, LV5FU or Folfiri, Oxycodone
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Effectiveness and Safety of the Seldinger Wire Technique Using a 145 cm Guidewire With the Modified Seldinger Technique Using a 70 cm Guidewire
Non-Inferiority Study to Compare the Effectiveness of the Seldinger Over-the-Wire Technique and the Modified Seldinger Technique
Peripherally inserted central venous catheter lines (PICC-line) are successfully used since many years in patients who need long-term frequent IV therapy.
- Trial name
- Over-the-Wire (NCT04303052)
- Testing
- Angiodynamic Bioflo Picc IR-KIT (145 cm guidewire) or, Angiodynamic Bioflo Picc MST-KIT (70 cm guidewire)
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Jena University Hospital
Acute Pain
Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain
The purpose of this research study is to determine which opiate pain medication (morphine or hydromorphone (Dilaudid)) is more effective in the treatment of acute pain in patients presenting to the emergency department.
- Trial name
- NCT00305058
- Testing
- Morphine, Hydromorphone
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Back Pain, Neck Pain
Cannabis Versus Oxycodone for Pain Relief
This study investigates the ability of cannabis to reduce chronic back and neck pain and to reduce sensitivity to an acute painful stimulus. Cannabis will be compared to both oxycodone and a placebo.
- Trial name
- NCT02892591
- Testing
- Cannabis, Oxycodone
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dermatitis, Radiation Induced
Retrospective Analysis of the Efficacy of Morphine Gel to Treat Pain Associated With Perineal RadioDermatitis
Retrospective study evaluating the efficacy of a pharmacy-prepared Morphine gel used in clinics for the treatment of pain associated with perineal radiodermatitis.
- Trial name
- ANTAGEL (NCT07207889)
- Testing
- morphine chlorhydrate in intrasite gel
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Institut Curie
Osteoarthritis, Hip
Effect of Local Infiltration Anesthesia With Ropivacaine on Pain After Primary Total Hip Arthroplasty
Background: The Local infiltration analgesic (LIA) technique has been widely used to reduce opioid requirements and improve the patient's mobilization after total hip arthroplasty (THA).
- Trial name
- NCT02359136
- Testing
- local infiltration anesthesia using Ropivacaine and Epinephrine, local infiltration anesthesia using saline, Multimodal analgesic regimen
- Where
- Norway
- Volunteers
- 116 people
- Sponsor
- St. Olavs Hospital
Pain, Postoperative
Outcomes Of Perioperative Pregabalin On Total Knee Arthroplasty
This study aims to provide high quality evidence from a double-blinded, randomized controlled trial on the efficacy of perioperative pregabalin in reducing morphine requirements, improving pain scores and reducing chronic…
- Trial name
- NCT02954484
- Testing
- pregabalin, Etoricoxib, paracetamol
- Volunteers
- 116 people
- Sponsor
- National University Hospital, Singapore
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