Clinical trials: Oxycodone, completed
Anterior Cruciate Ligament Reconstruction
Anterior Cruciate Ligament Pain Study
The objective of this study is to compare the pain control benefit of two different types of nerve blocks in patients undergoing anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT02604550
- Testing
- Ropivacaine 0.5%, Percocet 7.5/325, Naprosyn 500 mg
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Emory University
Pain, Postoperative
Study of Buprenorphine Sublingual Spray Versus Standard of Care Narcotic Therapy for the Treatment of Post-Operative Pain
This study will evaluate the safety and tolerability based on the incidence of adverse experiences of buprenorphine sublingual spray (0.5 milligrams [mg] three times daily [TID]) compared with standard post-operative narcotic…
- Trial name
- NCT03254459
- Testing
- Buprenorphine Sublingual Spray, Morphine, Oxycodone Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- INSYS Therapeutics Inc
Pain
A Study to Evaluate Safety and Efficacy Following Dosing of Oxycodone/Naltrexone for Treatment of Adults With Pain Following Bunionectomy Surgery
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, Phase 3 study to evaluate the efficacy and safety of the administration of multiple doses of Oxycodone Hydrochloride plus Naltrexone…
- Trial name
- NCT02401750
- Testing
- Oxycodone Naltrexone (a), Oxycodone Naltrexone (b)
- Where
- 5 sites in United States
- Volunteers
- 163 people
- Sponsor
- Elite Laboratories, Inc
Hysterectomy, Myoma
Morphine vs. Oxycodone for Postoperative Pain Management
The purpose of this study is to determine whether oxycodone provides better analgesia compared to morphine after laparoscopic hysterectomy or myomectomy.
- Conditions
- Hysterectomy, Myoma, Postoperative Pain, Opioids
- Trial name
- NCT00528177
- Testing
- Morphine and oxycodone
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Ullevaal University Hospital
Abuse Potential
Study Evaluating the Abuse Potential of NEURONTIN® in Healthy Non-drug Dependent, Recreational Opioid Users
This will be a randomized, double-blind, double-dummy, placebo- and active-controlled, 6 treatment, 6-period crossover single-dose, Williams square design study in healthy male and/or female adult, non-drug-dependent recreational…
- Trial name
- NCT05319756
- Testing
- gabapentin 600 mg, gabapentin 1200 mg, gabapentin 600 mg and oxycodone HCl 20 mg
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Viatris Specialty LLC
Nonspecific Pain Post Traumatic Injury
MAST Trial: Multi-modal Analgesic Strategies in Trauma
This is a comparative effectiveness study of current pain management strategies in acutely injured trauma patients. Two different multi-modal, opioid minimizing analgesic strategies will be compared [original multimodal pain…
- Trial name
- MAST (NCT03472469)
- Testing
- Acetaminophen IV/PO, Acetaminophen PO, Ketorolac
- Where
- United States
- Volunteers
- 1,561 people
- Sponsor
- The University of Texas Health Science Center, Houston
Post-operative Pain
Role of Pregabalin in Treatment of Post-Op Pain in Fracture Patients
This is a randomized, prospective, double-blind pilot study designed to evaluate the potential effectiveness of pregabalin in post-operative pain management for patients who have sustained a fracture.
- Trial name
- LYRICA (NCT00583869)
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis, Hip
Prolonged Multimodal Analgesia for Post-Discharge Pain Control After Primary Total Hip Arthroplasty
This is a prospective, three-arm, comparative study with a provider-crossover design. The first arm will comprise the standard of care pain regimen after discharge, which comprises PRN oxycodone, tramadol, and acetaminophen.
- Trial name
- NCT03358888
- Testing
- Multi-modal with as needed opioids, Multi-modal with one week of opioids offered, Standard of Care
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- Rothman Institute Orthopaedics
Pain
Pharmacokinetics And Relative Bioavailability Study Of Oxycodone
To estimate the pharmacokinetics and relative bioavailability of oxycodone after administration of 40 mg doses of four PF-00345439 formulations and oxycodone in solution
- Trial name
- NCT01552850
- Testing
- Oxycodone
- Where
- Singapore
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pain Therapeutics
Cancer, Pain
Oxycodone and Pregabalin for the Treatment of Oncological Neuropathic Pain
The aim of the study is to assess tolerability and activity of oxycodone and pregabalin in combination for the treatment of oncological neuropathic pain with two different strategies.
- Trial name
- NCT00637975
- Testing
- oxycodone, pregabalin
- Where
- 8 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Associazione Progetto Oncologia UMAN.A
Cancer Pain, Neoplasms
GREAT - Good Response With Appropriate Treatment
The symptoms associated in advanced cancer patients and adverse events due to use of opioids have major influence on the state of health and quality of life of patients.
- Trial name
- NCT02293785
- Testing
- Oxycodone-Naloxone
- Where
- 18 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Bunion, Post-operative Pain
CPL-01 in the Management of Postoperative Pain After Bunionectomy
Subjects receive study drug during bunionectomy and are followed for pain and opioid use, with the hypothesis that those who receive CPL-01 will have less pain and less opioid use than either control arm.
- Trial name
- NCT05831449
- Testing
- Local anesthetic injection of CPL-01, Naropin, 0.5% Injectable Solution, Morphine rescue medication
- Where
- United States
- Volunteers
- 616 people
- Sponsor
- Cali Pharmaceuticals LLC
Post Operative Pain
OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty
The purpose of this study is to demonstrate that treatment with OXN PR tablets is non inferior to treatment with OXY PR tablets in terms of analgesic efficacy in patients with postoperative pain after knee arthroplasty based on…
- Trial name
- OXN4505 (NCT01083485)
- Testing
- Oxycodone/Naloxone PR 20/10mg or 10/5mg tablets, Oxycodone
- Where
- Finland
- Volunteers
- 137 people
- Sponsor
- Mundipharma Oy
Clavicular Fracture, Pain, Acute
Ultrasound-guided Block of the Supraclavicular Nerves in Clavicular Fractures
A Clavicular fractures (CF) is uncomfortable for the affected patients because the fragments are often strongly displaced by the muscles attached to them and the bony fragments move painfully with every movement of the shoulder.
- Trial name
- US-SCNB_Clav (NCT04685291)
- Testing
- Ultrasound-guided block of the supraclavicular nerves, Conventional pain management
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Eckehart SCHÖLL
Gastric-bypass Surgery, Opioid Consumption
Transversus Abdominis Plane (TAP) Block in Laparoscopic Gastric-bypass Surgery
Laparoscopic gastric-bypass surgery (LGBS) is one of the surgical treatments for morbid obesity, which is performed under general anesthesia.
- Conditions
- Gastric-bypass Surgery, Opioid Consumption, Obesity
- Trial name
- NCT01568437
- Testing
- TAP-Block, Conventional Managment
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University Health Network, Toronto
Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy
This trial studies how well gabapentin, methadone, and oxycodone with or without venlafaxine hydrochloride work in managing pain in participants with stage II-IV squamous cell head and neck cancer undergoing chemoradiation…
- Trial name
- NCT03574792
- Testing
- Gabapentin, Methadone, Oxycodone
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Roswell Park Cancer Institute
Non Cancer Pain
Targin for Non-cancer Pain
To determine the improvement in symptoms of constipation in subjects receiving treatment with oxycodone/naloxone prolonged release tablets (OXN) compared to oxycodone prolonged release tablets (OXY) based on the Bowel Function…
- Trial name
- NCT01918098
- Testing
- Oxycodone/naloxone prolonged release tablets
- Where
- 31 sites in China
- Volunteers
- 230 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Low Back Pain
Linking Altered Central Pain Processing and Genetic Polymorphism to Drug Efficacy in Chronic Low Back Pain (Predictio)
Drug therapy in patients with chronic low back pain is a major challenge for physicians. One of the problems is the lacking knowledge in prediction of drug efficacy in a chosen patient.
- Trial name
- Predictio (NCT01179828)
- Testing
- Oxycodone 15mg, Clobazam, Imipramine
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Arthroplasty, Replacement, Hip
Oxycodone Versus Intravenous Morphine for Postoperative Analgesia After Hip Surgery
The main objective is to demonstrate that postoperative analgesia by IV oxycodone (compared to morphine IV) reduces opioid-related adverse events (nausea, vomiting, pruritus, respiratory depression, urinary retention, allergies…
- Trial name
- NCT01536301
- Testing
- Standard Care morphine hydrochloride, Oxycodone
- Where
- 2 sites in France
- Volunteers
- 246 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Rhinosinusitis (Diagnosis)
Effect of Post-operative Ibuprofen After Surgery for Chronic Rhinosinusitis
Endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) is a common procedure in the US, with about 250,000 cases performed annually.
- Trial name
- NCT03055507
- Testing
- Ibuprofen 400 mg, Acetaminophen 650 mg, OxyCODONE 5 Mg Oral Tablet
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Washington