Clinical trials: Paracetamol
Supracondylar Humerus Fracture
Post-operative Pain Management in Children With Supracondylar Humerus Fractures
There are two common and concurrently used strategies for pain management following surgical treatment of supracondylar humerus (elbow) fractures in children: opioids vs over the counter pain medications.
- Trial name
- NCT05640674
- Testing
- Ibuprofen, Hydrocodone/acetaminophen, Acetaminophen
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Baylor College of Medicine
Cesarean Section, Pain, Postoperative
RCT (Randomized Controlled Trial) of IV Acetaminophen for Post Cesarean Pain Relief
This study is being done to evaluate the scheduled use of intravenous (IV) acetaminophen among cesarean section patients. The study hopes to find out if patients who receive scheduled IV acetaminophen for 48 hours following…
- Trial name
- NCT02046382
- Testing
- IV Acetaminophen
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- TriHealth Inc.
Osteoarthritis, Knee
Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN
A previous multicenter trial led by Bioiberica S.A. has confirmed the efficacy and safety of DROGLICAN for the treatment of osteoarthritis (OA) in patients with severe pain.
- Trial name
- DRIP (NCT02821468)
- Testing
- Droglican, Paracetamol or oral NSAIDs excluding COX2 inhibitors
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Bioiberica
Juvenile Idiopathic Arthritis, Gait, Frontal
Exercise Programs on Gait in Children JIA
Juvenile Idiopathic Arthritis (JIA) is one of the common chronic diseases in childhood. Problems such as weakness or pain may occur in JIA, especially in the joints and the muscles around the trunk.
- Trial name
- NCT06356350
- Testing
- Conventional neuromuscular exercises, Core based exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Osteoarthritis, Hip, Osteoarthritis, Knee
A Safety and Effectiveness Study of Acetaminophen (4000 mg/Day) and Naproxen (750 mg/Day) in the Treatment of Osteoarthritis of the Hip or Knee
The purpose of this study is to compare the long-term safety and effectiveness of acetaminophen (4000 mg per day) and naproxen (750 mg per day) in the treatment of osteoarthritis of the hip or knee.
- Trial name
- NCT00240773
- Testing
- acetaminophen, naproxen
- Volunteers
- 581 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Osteochondral Lesion of Talus
Extracorporeal Shock Wave Therapy for Pain-Relief After Arthroscopy for Osteochondral Lesions of the Talus
Arthroscopic surgery is effective in treating osteochondral lesions of the talus. However, there are still some patients with postoperative ankle pain.
- Trial name
- NCT03750253
- Testing
- Extracorporeal Shock Wave Therapy
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Southwest Hospital, China
IgG4 Related Disease, IgG4-RD
Elotuzumab in Immunoglobulin G4-Related Disease (IgG4-RD)
This is a two-part multi-center clinical trial in participants with active IgG4-RD. Part 1 (Cohort 1a and Cohort 1B) is an open-label, dose escalation phase to determine the safety of elotuzumab for investigation in IgG4-RD.
- Trial name
- NCT04918147
- Testing
- elotuzumab, methylprednisolone, diphenhydramine
- Where
- 3 sites in United States
- Volunteers
- 8 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Inflammatory Response, Anesthesia
Effect of Peng Block Application on Inflammation and Mortality in Hip Fractures
In this study, the investigators the effect of PENG block on SIRI (systemic inflammation response index) and 30-day mortality in geriatric patients(over 65 years old) undergoing hip surgery, and the effect on the length of…
- Conditions
- Inflammatory Response, Anesthesia, Hip Fractures
- Trial name
- NCT06795724
- Testing
- PENG block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Oxidative Stress, Sevoflurane Anaesthesia
Effect of Paracetamol Administration Timing on Oxidative Stress in Children Undergoing Sevoflurane Anesthesia
This study investigated the effects of paracetamol administration on oxidative stress in children undergoing inguinal hernia surgery under sevoflurane-based general anesthesia.
- Trial name
- NCT07903259
- Testing
- paracetamol (acetaminophen) solution commercial
- Where
- Serbia
- Volunteers
- 49 people
- Sponsor
- University of Belgrade
Clinical Audit, Quality Improvement
Impact Evaluation of the Therapeutic Initiative's Prescribing Portrait and Therapeutics Letter on Opioid Use by Dentists
The aim of this study is to estimate the impact of providing personalized prescribing data and educational materials on opioid prescribing to dentists in British Columbia, Canada. The main research questions are: 1.
- Conditions
- Clinical Audit, Quality Improvement, Opioid, Dentistry
- Trial name
- NCT07317869
- Testing
- Regular intervention, Enhanced intervention
- Where
- Canada
- Volunteers
- 3,498 people
- Sponsor
- University of British Columbia
Curettage, Analgesia
Pain and Suction Curettage
Aim of the study was to investigate the analgesic efficacy of preoperative oral dexketoprofen trometamol, intravenous paracetamol, lidocaine spray and paracervical block with ultracaine on curettage procedure.
- Conditions
- Curettage, Analgesia, Paracervical Block, Paracetamol
- Trial name
- NCT01947205
- Testing
- paracetamol, dexketoprofen trometamol, suction curettage
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Gökhan Açmaz
Amniocentesis
Oral Paracetamol Premedication Effect on Maternal Pain in Amniocentesis
This randomized controlled trial, compares perioperative and postoperative pain score by using visual analog scale in pregnant women undergoing amniocentesis.
- Trial name
- NCT03035045
- Testing
- Paracetamol
- Where
- Thailand
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Chronic Pain
A Study to Assess the Improvement of Pain and Health-Related Quality of Life in Patients With Chronic Non-Malignant Pain Taking Tramadol Hydrochloride and Acetaminophen
The purpose of this study is to evaluate the impact of extended release tramadol hydrochloride (75 mg) and acetaminophen (650 mg) tablets on improvement of pain.
- Trial name
- NCT01819805
- Testing
- No intervention
- Where
- 14 sites in South Korea
- Volunteers
- 1,065 people
- Sponsor
- Janssen Korea, Ltd., Korea
Complications; Cesarean Section
Preoperative Cesarean Section Intravenous Acetaminophen and Postoperative Pain Control
To evaluate the use of maternal opiates for pain control post cesarean delivery in those patients that received intravenous acetaminophen 1000 mg in 150 mL of normal saline, infused 30 minutes prior to incision compared to…
- Trial name
- NCT02694653
- Testing
- Acetaminophen
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Inguinal Hernia Bilateral, Postoperative Pain
M-TAPA vs OSTAP for Postoperative Analgesia in Laparoscopic Inguinal Hernia
This randomized controlled trial aims to compare the postoperative analgesic efficacy of M-TAPA block and OSTAP block in patients undergoing laparoscopic inguinal hernia repair.
- Trial name
- NCT07522853
- Testing
- Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA), Oblique Subcostal Transversus Abdominis Plane Block (OSTAP), Standard Analgesia use (paracetamol, contramal)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Healthy Volunteers
Pharmacokinetic Study of a Fixed Dose Combination Nefopam Hydrochloride (30 mg) / Paracetamol (500 mg)
This study aims to assess the pharmacokinetic profile of a Fixed Dose Combination nefopam hydrochloride (30 mg) / paracetamol (500 mg) and individual components taken alone or concomitantly after oral single dose.
- Trial name
- ARL/20/277 (NCT05129137)
- Testing
- nefopam hydrochloride 30mg X2, paracetamol 500 mg X2, Combination Product: nefopam hydrochloride 30mg / paracetamol 500mg X2
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Unither Pharmaceuticals, France
Impacted Third Molar Tooth, PAIN
An Randomized Control Trial Comparing Two Drug Combinations for Pain Management After Third Molars Surgery
Randomised control clinical trial to compare which combination of analgesics in effective in pain management after third molar extraction of wisdom teeth.
- Trial name
- NCT04874675
- Testing
- diclofenac / acetaminophen /codeine, ibuprofen/acetaminophen/codeine
- Where
- Zimbabwe
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Breast Cancer, Pain, Postoperative
Erector Spinae Plane Block Versus Paravertebral Block
This study aims to compare the effectiveness of paravertebral block and erector spinae plane block after mastectomy. The primary objective of this randomized controlled trial is to demonstrate equivalent dermatomal spread for…
- Conditions
- Breast Cancer, Pain, Postoperative, Anesthesia, Local
- Trial name
- NCT03471442
- Testing
- Paravertebral block, Erector spinae plane block, General anesthetic
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Alberta
Postoperative Pain
Analgesic Effect of Superficial Cervical Plexus Block in Postoperative Neck Surgeries
analgesic effect of superficial cervical plexus block by using ultrasound in patients undergoing neck surgeries
- Trial name
- NCT07539935
- Testing
- superficial cervical plexus block guided by ultrasound with bupivacaine, Paracetamol (500 mg) tablets
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Postoperative Pain Following Knee Arthroplasty
Evaluating Suzetrigine for Pain Control Following TKA
The goal of this clinical trial is to learn if a non-opioid pain medicine called suzetrigine works to treat pain after total knee replacement surgery in adults. It will also learn about the safety of suzetrigine.
- Trial name
- NCT07357376
- Testing
- Suzetrigine
- Volunteers
- 210 people
- Sponsor
- AdventHealth
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.