Clinical trials: Paracetamol, completed
Healthy
Emulsion Lipid Digestion & Satiety Study - Effect of Physical State and Acid Stability
The purpose of this study is to compare the changes in blood lipids and feelings of satiety after consumption of acid stable or acid unstable oil-in-water emulsions in which the droplets are in either the liquid or partially…
- Trial name
- NCT03990246
- Testing
- Acid stable emulsion with solid droplets, Acid stable emulsion with liquid droplets, Acid unstable emulsion with solid droplets
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Paediatric, Surgery
Erector Spinae Plane Block for Paediatric Upper Abdominal Surgery
Upper abdominal surgeries are associated with severe postoperative pain. Thus, maintaining effective postoperative analgesia in the paediatric age group is very crucial in terms of future pain perception and chronic pain…
- Conditions
- Paediatric, Surgery, Analgesia, Anesthesia
- Trial name
- NCT04518215
- Testing
- Erector Spinae Plain Block, Intra-Venous Analgesia
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Nazmy Edward Seif
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia
Allo HSCT Using RIC for Hematological Diseases
This is a phase II trial using a non-myeloablative cyclophosphamide/ fludarabine/total body irradiation (TBI) preparative regimen followed by a related or unrelated donor stem cell infusion.
- Conditions
- Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia
- Trial name
- NCT02661035
- Testing
- Allopurinol, Fludarabine, Cyclophosphamide
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Retinopathy of Prematurity, Pain Management
Pain Management During Screening for Retinopathy of Prematurity
Abstract Background: Screening examinations for retinopathy of prematurity (ROP) is critical to reduce ROP-related vision loss, however, the procedure is painful and uncomfortable, and topical anesthetics do not completely…
- Trial name
- NCT04767178
- Testing
- Ibuprofen (Sanofi, Istanbul, Turkey), Paracetamol (GlaxoSmithKline, Istanbul, Turkey)
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul Medeniyet University
Postoperative Pain
Thoracic Paravertebral Block in Pain Management After Renal Surgery
Objective: The objective of the study was to assess the usefulness of ThPVB in postoperative pain management after open renal resection surgery.
- Trial name
- NCT02840526
- Testing
- Paravertebral blockade (PVB), Sopodorm, Propofol WZF
- Where
- Poland
- Volunteers
- 58 people
- Sponsor
- Silesian University of Medicine
Pain, Fever
Pharmacokinetics, -Dynamics and Safety of Intravenous Paracetamol in Neonates
The purpose of this study is triple, i.e. document single dose pharmacokinetics and -dynamics of intravenous paracetamol in preterm and term neonates after a loading dose (20 mg/kg iv bolus paracetamol), document multiple dose…
- Trial name
- PARANEO (NCT00969176)
- Testing
- paracetamol
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pain Management
Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)
Oxycodone and Hydrocodone are the most commonly used oral opioid analgesics in the emergency department and in outpatient settings.
- Trial name
- NCT03088826
- Testing
- Morphine Sulfate, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Antonios Likourezos
Hip Arthroplasty, Knee Arthroplasty
Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery
Patients over 70 years of age, scheduled for joint replacement surgery will be randomized to tramacet/ naloxone plus morphine PCA or to morphine PCA to assess quality of analgesia in the postoperative period.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia
- Trial name
- NCT00679614
- Testing
- tramacet, naloxone, tramacet, Acetaminophen
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Acute Post-operative Pain Following Caesarean Section
Opioid-free Analgesia for the Management of Acute Post-operative Pain Following Caesarean Section
Background: Multimodal analgesia; a combination of opioid and non-opioid analgesics, for management of acute post-operative pain significantly reduces the incidence of adverse effects associated with liberal post-operative opioid…
- Trial name
- OFAAPPCS (NCT04539249)
- Testing
- Magnesium sulphate, Pentazocine
- Where
- Nigeria
- Volunteers
- 324 people
- Sponsor
- Olakunle Ifeoluwa Makinde
Breast Cancer, Pain, Acute
ESP in Breast Surgery Due to Cancer
Patients scheduled for breast surgery due to cancer. Each patient will be treated with intravenous (i.v.) oxycodone - patient-controlled analgesia (PCA).
- Conditions
- Breast Cancer, Pain, Acute, Anesthesia, Local
- Trial name
- NCT04726878
- Testing
- Erector spinae plane block, General anesthesia, Patient-controlled analgesia
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Medical University of Lublin
Thyroid Disease, Parathyroid Diseases
Pain Medications Following Thyroidectomy and Parathyroidectomy
The purpose of this study is to evaluate the use of a non-narcotic, postoperative pain management regimen on patients undergoing thyroidectomy and parathyroidectomy.
- Trial name
- NCT03640247
- Testing
- Non-narcotic group regimen, Narcotic group regimen
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- MetroHealth Medical Center
Pain
Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain
This study will compare the analgesic efficacy of a single-dose of a novel ibuprofen formulation to placebo and acetaminophen in the treatment of post-surgical dental pain following "wisdom" tooth (third molar) removal.
- Trial name
- NCT01216163
- Testing
- Novel Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Pfizer
Morbid Obesity, Anesthesia Complication
Low Flow Anesthesia in Morbid Obesity
In this study to planned to research the efficacy of low-flow anesthesia on patients undergoing sleeve gastrectomy due to morbid obesity on respiratory functions after surgery by examining FEV1 and FVC values and FEV1/FVC ratio.
- Conditions
- Morbid Obesity, Anesthesia Complication, Anesthesia; Functional
- Trial name
- NCT03913858
- Testing
- Obesity Surgery with Low-Flow Anesthesia, Obesity Surgery with High-Flow Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Healthy
Study of the Effects of ITCA 650 on Gastric Emptying and Interaction of ITCA 650 on 4 Commonly Studied Drugs
A Phase 1, Fixed-Sequence, Open-label Study in Healthy Subjects to Estimate the Effects of ITCA 650 on Gastric Emptying and on the Absorption Pharmacokinetics of Each of 4 Commonly Studied DDI Probe Compounds.
- Trial name
- NCT02641899
- Testing
- ITCA 650 20/60 mcg/day, Acetaminophen, Atorvastatin
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Intarcia Therapeutics
Migraine With or Without Aura
Low-Dose Naltrexone and Acetaminophen Combination and Its Components in the Acute Treatment of Migraine
The study consists of a screening visit, out-patient treatment of a moderate or severe migraine attack with a single dose of the study medication within 8 weeks, and End-of-Study Visit 2-7 days after dosing.
- Trial name
- ANODYNE-1 (NCT03061734)
- Testing
- Naltrexone and Acetaminophen, Naltrexone and Acetaminophen-High Dose, Naltrexone Alone (regular dose)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Allodynic Therapeutics, Inc
Neck Pain
Auto-acupressure: Effectiveness for Diminishing Neck Pain of Benign Origin
The purpose of this study is to evaluate the effectiveness of the auto-acupressure (digital pressure in points of acupuncture) added to the conventional treatment.
- Trial name
- NCT01855893
- Testing
- Auto-acupressure, Conventional treatment
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Pain
A Randomized Control Trial on Intravenous Paracetamol Versus Intramuscular Tramadol as Intra Partum Labor Analgesia
ABSTRACT BACKGROUND: Labor pain is one of the most excruciating pain experienced by women. It affects maternal psychology and the course of labor causing apprehension, anxiety, and stress.
- Trial name
- NCT06371144
- Testing
- Paracetamol
- Where
- Nigeria
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Asthma, Rheumatic Disease
Acetaminophen (Tylenol) for Mood and Memory Changes Associated With Corticosteroid Therapy
Studies in humans and animals support that stress and/or elevations in corticosteroids lead to changes in hippocampal structure and functioning.
- Trial name
- NCT00377364
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas Southwestern Medical Center
Carpal Tunnel Syndrome, Dupuytren Contracture
Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery
This study is about pain control and medication following outpatient soft-tissue hand surgery. We hope to learn if ibuprofen and acetaminophen will achieve similar pain relief and satisfaction when compared with oxycodone alone.
- Conditions
- Carpal Tunnel Syndrome, Dupuytren Contracture, Trigger Digit, Ganglion Cysts
- Trial name
- NCT03111186
- Testing
- Oxycodone Hcl 5Mg, Ibuprofen 400 mg, Acetaminophen 650 mg
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Southern California
Pain, Postoperative, Coronary Artery Disease
Pecto-Intercostal Fascial Block vs. Transversus Thoracic Muscle Plane Block in Cardiac Surgery
In patients undergoing open cardiac surgery, pain control is an essential part of the enhanced recovery process. The current study aimed to evaluate the analgesic efficacies of ultrasound-guided pecto-intercostal fascial block…
- Trial name
- NCT04791592
- Testing
- Single-injection, ultrasound-guided bilateral PIF block., Single-injection, ultrasound-guided bilateral TTMP block.
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ondokuz Mayıs University
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