Clinical trials: Paracetamol, completed
Pharmacological Action, Post Operative Pain
The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric Surgery
The goal of this observational study is to evaluate the quality of postoperative analgesia in a group of obese patients schedule to bariatric surgery under TIVA Opiod-free after to receive lidocaine and ketamine perfusion.
- Conditions
- Pharmacological Action, Post Operative Pain, Opioid Use, Obesity, Morbid
- Trial name
- NCT05591105
- Testing
- Control Group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Tiva Group
Temporomandibular Disorders
Effectiveness of a Counseling Program for Temporomandibular Disorders (TMD) Treatment
This study aims to evaluate the effectiveness of counseling on pain, function and well-fare outcomes for the management of patients with temporomandibular disorder (TMD).
- Trial name
- NCT02380105
- Testing
- Counseling, Interocclusal Appliances
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Postoperative Nausea and Vomiting, Postoperative Nausea and Vomiting \(PONV\)Acuppressure
P6 Acupressure Band for Prevention of Postoperative Nausea and Vomiting in Children
Nausea and vomiting after surgery are one of the most common side effects of general anaesthesia. Pressure at P6 acupuncture point around wrist area using acupressure band has been proven to reduce nausea and vomiting in adult.
- Trial name
- NCT06046027
- Testing
- Accupressure band
- Where
- Malaysia
- Volunteers
- 64 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Nonspecific Pain Post Traumatic Injury
MAST Trial: Multi-modal Analgesic Strategies in Trauma
This is a comparative effectiveness study of current pain management strategies in acutely injured trauma patients. Two different multi-modal, opioid minimizing analgesic strategies will be compared [original multimodal pain…
- Trial name
- MAST (NCT03472469)
- Testing
- Acetaminophen IV/PO, Acetaminophen PO, Ketorolac
- Where
- United States
- Volunteers
- 1,561 people
- Sponsor
- The University of Texas Health Science Center, Houston
Vertebral Fracture
Anesthesia Methods on Percutaneous Kyphoplasty
The aim of this research is to examine the effects of the anesthesia method and preoperative characteristics on postoperative results and complications in patients who underwent percutaneous kyphoplasty (PKP).
- Trial name
- NCT05526794
- Testing
- Analgesic consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Evidence of Liver Transplantation, Rejection
Safety and Efficacy of Alemtuzumab in Pediatric Intestinal Transplantation
This open-label clinical trial will evaluate the safety and efficacy of Alemtuzumab (Campath, Bayer Corp., Pittsburgh) in children (0-17) and adults (18-25) receiving intestinal transplant.
- Conditions
- Evidence of Liver Transplantation, Rejection, ALEMTUZUMAB
- Trial name
- NCT01208337
- Testing
- Alemtuzumab
- Volunteers
- 23 people
- Sponsor
- University of Pittsburgh
Post Operative Pain
Comparison of Tramacet Versus Percocet in Post Surgical Patients
Opioid naive patients are randomized to receive either TRAMACET or PERCOCET at the time of discharge following mild to moderate pain risk surgery. The following will be assessed: 1) Brief pain inventory (BPI) for the month.
- Trial name
- NCT02361567
- Testing
- Tramacet, Percocet
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Children, Lacerations
Pain and Anxiety Management With Oral Narcotic for Pediatric Suture Repair
The purpose of this study is: To determine whether oral narcotic medication versus placebo improves the pain and anxiety scores for pediatric patients requiring laceration repair in the pediatric emergency department and…
- Conditions
- Children, Lacerations, Procedures, Child
- Trial name
- NCT01053637
- Testing
- hydrocodone/acetaminophen, Sugar water
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Baylor College of Medicine
Pain
A 12-Week Efficacy Study of Paracetamol 1000mg Sustained-release Tablets in Patients With Osteoarthritis
The purpose of the study is to determine whether paracetamol 1000 mg sustained-release (SR) tablets administered orally, twice daily are effective and safe in the treatment of patients with osteoarthritis of the knee or hip.
- Trial name
- NCT02311881
- Testing
- Paracetamol 1000 mg SR tablets, Paracetamol 665 mg SR tablets
- Where
- 56 sites in United States
- Volunteers
- 960 people
- Sponsor
- GlaxoSmithKline
Obesity
A Research Study Looking at How the Compound NNC0487-0111 Works With Birth Control Pills and Affects Emptying of the Stomach in Women Not Able to Become Pregnant
This study medicine NNC0487-0111 to improve the treatment options for people living with overweight and obesity or with type 2 diabetes.
- Trial name
- NCT06461039
- Testing
- NNC0487-0111 A, NNC0487-0111 C, Levonorgestrel 150 μg + Ethinylestradiol 30 μg (Oral contraceptive OC)
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- Novo Nordisk A/S
Total Hip Arthroplasty, Postoperative Pain
PENG Block vs Intrathecal Morphine in Total Hip Arthroplasty
To compare the impact of pericapsular nerve group (PENG) block to intrathecal morphine on postoperative analgesia, motor function and side effects in patients undergoing primary total hip arthroplasty under spinal anesthesia.
- Trial name
- NCT05308420
- Testing
- Pericapsular nerve group (PENG) block, Spinal anesthesia, Intrathecal morphine
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Kresimir Oremus, MD
Pregnancy Related Low Back Pain
Use Ear Acupuncture as Treatment for Low Back Pain During Pregnancy
Ear acupuncture can be used as a treatment for pregnancy induced low back pain.
- Trial name
- NCT00571480
- Testing
- acupuncture, standard of care
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Yale University
Dementia, Pain
Pain in Patients With Dementia and Behavioural Disturbances
In nursing homes (NHs) 80% of the patients have dementia, between 60%-80% exhibit behavioural disturbances (BPSD), and more than 60% have pain. Both pain and BPSD is more common in those with severe dementia.
- Conditions
- Dementia, Pain, Agitation
- Trial name
- NCT01021696
- Testing
- Paracetamol, Morphine, Buprenorphine plaster
- Where
- 18 sites in Norway
- Volunteers
- 352 people
- Sponsor
- University of Bergen
Cesarean Section Complications
Towards Enhanced Recovery After Cesarean
One in 300 women will become persistent opioid users after cesarean delivery (1). Cesarean delivery is the most common surgical procedure in the United States, representing 31.9% of the 3,788,235 deliveries in 2018 (2).
- Trial name
- ERAS (NCT04612920)
- Testing
- Ibuprofen, acetaminophen, oxycodone
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Oklahoma
Upper Respiratory Infections
Warming Sensation Intensity and Acceptability of the Flavour, Local Tolerability of Paracetamol 500 mg + Pseudoephedrine 30 mg Syrup in Patients Suffering a URTI
This is an open label, in-use study to assess the warming sensation, acceptability and local tolerability of paracetamol 500 mg + pseudoephedrine 30 mg syrup, given as a single dose in subjects suffering from symptoms of an upper…
- Trial name
- NCT01586962
- Testing
- IFF flavor 316 282, Paracetamol, Pseudoephedrine
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Novartis
Lung Cancer
Comparison of Efficacy of Paravertebral and Epidural Analgesia After Videothoracoscopic Lung Lobectomy
Thoracic surgery correlates with significant pain in postoperative period. In order to alleviate the pain various combinations of pharmaceuticals and administration methods are employed.
- Trial name
- NCT02040662
- Testing
- Continuous Thoracic Epidural Block, Continuous Thoracic Paravertebral Block, Patient-Controlled Analgesia with Morphine
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Pulmonary Hospital Zakopane
Pain, Postoperative
Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients
This is a prospective, randomized, double-blinded, placebo controlled trial Potential subjects will be identified from the Pre-Surgical Anesthesia Clinic visit.
- Trial name
- IV APAP SF (NCT01394718)
- Testing
- Intravenous Acetaminophen
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Children's Hospital of Philadelphia
Osteoarthritis
Study To Determine The Effects Of Doses Of Relacatib On The Metabolism Of Acetaminophen, Ibuprofen And Atorvastatin
Relacatib is being developed for the treatment of osteoporosis, osteoarthritis and possibly other bone disorders. Recent results suggest that relacatib interacts with the way our bodies metabolise drugs and so some drugs which…
- Trial name
- NCT00411190
- Testing
- Relacatib, Acetaminophen, Ibuprofen
- Where
- 2 sites in Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Spondylosis Lumbar
Battlefield Acupuncture as an Adjunct to Electroacupuncture for Chronic Low Back Pain Due to Lumbar Spine Osteoarthritis
Chronic low back pain due to lumbar spine osteoarthritis is a common and disabling condition. Many patients do not get enough relief from standard treatments.
- Trial name
- NCT06874959
- Testing
- Battlefield Acupuncture (BFA), Electroacupuncture, Paracetamol 500 mg (as-needed)
- Where
- 2 sites in Vietnam
- Volunteers
- 60 people
- Sponsor
- Bui Pham Minh Man
Fever
The Effect of Prophylactic Antipyretics on Immune Responses and Fever After 2014-2015 and 2015-2016 Inactivated Influenza Vaccine
This study aims to conduct a double-blind, placebo-controlled study to assess the effect of prophylactic antipyretics on the immune responses and rates of fever after inactivated influenza vaccine (IIV) in children 6 through 47…
- Trial name
- NCT02212990
- Testing
- Acetaminophen Arm, Ibuprofen Arm
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Duke University
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