Clinical trials: Paracetamol, completed
Kidney Transplant Recipient, Kidney Transplant Donor
Investigation of the Effects of Quadratus Lumborum Block Applied to Patients in Kidney Transplant Surgery
This study aims to determine the most effective and long-lasting pain relief method for post-operative analgesia in kidney donor and recipient patients in kidney transplantation programme with the least invasive and least drug…
- Trial name
- NCT06011850
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Postoperative Pain, Hysterectomy
Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery
This study will be investigating the efficacy and safety administration of multiple doses of intravenous (IV) acetaminophen (IVAPAP) in the 48 hour period following Gynecologic Surgery.
- Trial name
- NCT00399568
- Testing
- IV Acetaminophen
- Where
- 27 sites in United States
- Volunteers
- 331 people
- Sponsor
- Mallinckrodt
Patent Ductus Arteriosus, Extreme Prematurity
Canadian National PDA Treatment Study
Patent ductus arteriosus (PDA) is the most common cardiovascular problem that develops in preterm infants. Persistent PDA may result in higher rates of death, chronic lung disease (CLD), pulmonary hemorrhage, necrotizing…
- Trial name
- CANRxPDA (NCT04347720)
- Testing
- Indomethacin, Ibuprofen, Acetaminophen
- Where
- 22 sites in Canada
- Volunteers
- 1,663 people
- Sponsor
- IWK Health Centre
Renal Colic
Oral NSAI Versus Paracetamol or Placebo as a Second Line Treatment for Renal Colics
Outpatients treatment with NSAI in renal colics has not been well investigated and there is no clear recommendations regarding this matter.
- Trial name
- ONSAIP-RC (NCT02304783)
- Testing
- Piroxicam, paracetamol
- Where
- Tunisia
- Volunteers
- 1,400 people
- Sponsor
- University of Monastir
Pain, Postoperative
Effect of Paracetamol, Pregabalin and Dexamethasone on Pain and Opioid Requirements in Patients After Hip Operations
Patients scheduled for primary total hip replacement needs postoperative pain treatment: i.e. morphine. Unfortunately morphine has side-effects: nausea, vomiting, sedation and dizziness, which is unpleasant for the patients and…
- Trial name
- NCT00235261
- Testing
- Pregabalin, Dexamethasone
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Surgery
Ambulatory Gynecologic Surgery: Finding the Optimal Opioid Prescription
Currently there is a nationwide epidemic in opioid abuse and overdose deaths. While the opioid epidemic is multi-factorial one major source of excess opioids may be over-prescribing in the post-operative period.
- Trial name
- NCT03588910
- Testing
- Acetaminophen, Ibuprofen 600 mg, Oxycodone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Laparoscopic Cholecystectomy, Quadratus Lumborum Block
Erector Spinae Plane Block Versus Subcostal Anterior Quadratus Lumborum Block in Laparoscopic Cholecystectomy
Adequate analgesic regimen is one of the most important key elements of Enhanced recovery after surgery (ERAS) protocols. The cornerstone of analgesia is multimodal analgesia combining local anesthetic (LA) techniques and trying…
- Conditions
- Laparoscopic Cholecystectomy, Quadratus Lumborum Block, Erector Spinae Plane Block
- Trial name
- NCT05158270
- Testing
- Ultrasound Guided Erector spinae plane block, Ultrasound Guided Subcostal Anterior Quadratus Lumborum Block, Intravenous Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Zagazig University
Post Mastectomy Pain Syndrome
Comparison Between Pregabalin and Acetaminophen for the Treatment of Post-Mastectomy Pain Syndrome
The goal of this trial is to learn if Pregabalin is better than Acetaminophen in pain management of patients with Post-Mastectomy pain Syndrome, which is defined as pain in the scar, chest wall, shoulder after undergoing…
- Trial name
- NCT07567924
- Testing
- Pregabalin, Acetaminophen
- Where
- Pakistan
- Volunteers
- 158 people
- Sponsor
- Subas Ali
Labour Pain
Combined Spinal-Epidural Versus Traditional Labor Epidural
The purpose of this study to compare the use of spinal-epidural versus traditional labor epidural on maternal and fetal effects.
- Trial name
- NCT00151346
- Testing
- Bupivacaine and Fentanyl (for CSE), Bupivacaine and Fentanyl (for traditional epidural)
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Anxiety Disorders, Mood Disorders
Treating Emotional Disorders in Primary Care With Psychological Techniques
The strong demand for primary care (PC) services in Spain exceeds resources. Part of this demand is due to the increasing number of anxiety, depression, and somatization disorders that affect the general population.
- Conditions
- Anxiety Disorders, Mood Disorders, Somatization Disorder, Pain Disorder
- Trial name
- PsychPC (NCT01903096)
- Testing
- Cognitive Behavioral Treatment, Primary Care Treatment As Usual
- Where
- Spain
- Volunteers
- 1,126 people
- Sponsor
- Psicofundación: Fundación Española para Promoción, Desarrollo Científico y Profesional de la Psicolo
Plantar Fasciitis
A Trial of Custom Foot Orthoses for the Treatment of Plantar Heel Pain
This is a study investigating treatment of plantar fasciitis (heel pain). Physicians commonly prescribe specialized orthoses (shoe inserts) to treat heel pain.
- Trial name
- NCT00765843
- Testing
- orthoses
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- Rosalind Franklin University of Medicine and Science
Pain
The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen on Postoperative Pain After Spine Surgery
The analgesic effect of dexamethasone is not well described, but studies have shown that dexamethasone can be a safe part of a multimodal analgesic strategy after surgery.
- Trial name
- NCT01953978
- Testing
- Dexamethasone, Morphine, Zofran
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hemorrhoids, Fissure in Ano
Pre-Emptive Analgesia in Ano-Rectal Surgery
The perianal region is the region around the anus. Administering a pain medication before a surgery starts is called preemptive analgesia.
- Conditions
- Hemorrhoids, Fissure in Ano, Rectal Fistula, Anal Condyloma
- Trial name
- PEAARS (NCT02402543)
- Testing
- Gabapentin, Ketamine, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Vermont
Nasal Congestion
A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold
The study will evaluate the safety and efficacy of the study medical device plus standard of care versus standard of care in subjects between 3 and 48 months (inclusive) presenting symptoms of a common cold.
- Trial name
- NCT05365789
- Testing
- Blocked Nose Baby nasal spray, Standard of care
- Where
- Poland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Pain, Postoperative
PAracetamol and NSAID in Combination: A Randomised, Blinded, Parallel, 4-group Clinical Trial
Trial name: PAracetamol and NSAID in combination: A randomised, blinded, parallel, 4-group clinical trial Trial acronym: PANSAID Background: Effective postoperative pain management is essential for the well-being and…
- Trial name
- PANSAID (NCT02571361)
- Testing
- Paracetamol (1g x 4), Ibuprofen (400 mg x 4), Paracetamol (0,5 g x 4)
- Where
- 6 sites in Denmark
- Volunteers
- 556 people
- Sponsor
- Daniel Hägi-Pedersen
Emotional Pain
Effects of Acetaminophen on Hurt Feelings
The purpose of the study is to investigate whether ingestion of acetaminophen reduces the experience of hurt feelings.
- Trial name
- NCT00561288
- Testing
- acetaminophen, cornstarch
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pain, Postoperative
Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
This study will compare IV (intravenous) versus oral (PO) acetaminophen for postoperative pain after scheduled, elective Cesarean delivery.
- Trial name
- NCT02487303
- Testing
- Acetaminophen Intravenous, Acetaminophen Oral
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pain, Postoperative
Randomized Study Comparing the Use of Epidural Analgesia to Intravenous Narcotics for Laparoscopic Colorectal Resection.
Laparoscopic colorectal surgery (LCS) has gained wide acceptance in the treatment of various pathology from diverticular disease to colon cancer.
- Trial name
- NCT02086123
- Testing
- Epidural Analgesia, Parenteral Analgesia (Intravenous)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of California, Irvine
Arthritis Knee
Trial to Compare Femoral Nerve Block With Local Anaesthetic Injection for Post-operative Pain After Knee Replacement.
Pain after a knee replacement can impair recovery and use of the new knee. Having an injection to numb the femoral nerve is known to give good pain relief after the operation but may lead to slower mobilisation as it also…
- Trial name
- LIFT (NCT02288923)
- Testing
- Femoral nerve block, Local Infiltration Analgesia, Sub arachnoid analgesia
- Where
- United Kingdom
- Volunteers
- 199 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Healthy
Phase 1 Study of DW-0919 & DW-0920 in Healthy Male Volunteers Under Fasting Condition
The purpose of this study is to evaluate safety and pharmacokinetics of DW-0919 and DW-0920 in healthy male volunteers under fasting condition.
- Trial name
- DW0919-1003 (NCT01606059)
- Testing
- DW-0920, DW-0919
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
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