Clinical trials: Paracetamol, completed
Cesarean Section, Postoperative Pain
TAP vs QLB in Patients After Cesarean Delivery
Comparison of two types of analgesia after cesarean section All patients will be anesthetized with spinal technique. Ultrasound-guided transversus abdominis plane or quadratus lumborum block to treat postoperative pain.
- Trial name
- NCT03404908
- Testing
- TAP (transversus abdominis plane block), QL (quadratus lumborum block), Ropivacaine
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Lublin
Hands Osteoarthritis
Corticosteroid Intra-articular Injection in Hands Osteoarthritis
Objective - to evaluate the effectiveness and tolerance of intra-articular injections (IAI) of hexacetonide triamcinolone (HT) for the treatment of osteoarthritis (OA) in interphalangeal joints.
- Trial name
- NCT02102620
- Testing
- Intra-articular injection with corticosteroid, Intra-articular injection with lidocaine
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Pain
The Effect of Intravenous Acetaminophen on Post-Operative Pain After Craniotomy
The purpose of the study is to determine the efficacy of IV acetaminophen when administered to neurosurgical patients at the beginning and end of their surgery.
- Trial name
- NCT03445390
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Stanford University
Knee Osteoarthritis
Comparison of Acetaminophen and PRP Therapy for Knee OA
The purpose of this study is to test whether the platelet-rich plasma (PRP) intra-articular injection therapy is effective as an alternative treatment option in patients with mild knee osteoarthritis within a controlled…
- Trial name
- NCT01782885
- Testing
- Intra-articular injection of PRP, Acetaminophen
- Where
- Mexico
- Volunteers
- 543 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Pain
Naproxen Sodium/Acetaminophen Proof of Concept Dosing Study
Study assessing efficacy and safety of concomitantly dosed naproxen sodium with acetaminophen, compared with naproxen sodium, hydrocodone/acetaminophen and Placebo in a postoperative dental pain.
- Trial name
- NCT03879408
- Testing
- 440 mg naproxen sodium with 1000 mg acetaminophen, 220 mg naproxen sodium with 650 mg acetaminophen, 10 mg hydrocodone + 650 mg acetaminophen
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division
Nail Diseases, Nail Abnormality
Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia
The purpose of this study is to assess the safety and efficacy of ropivacaine and hydrocodone for nail-procedure associated pain management.
- Trial name
- NCT05544734
- Testing
- Hydrocodone 5Mg/Acetaminophen 325Mg Tab, Acetaminophen 1000mg, Ibuprofen 400 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Anesthesia, Postoperative Pain
RIB for Perioperative Analgesia in CIED Patients
Rhomboid intercostal plane block (RIB) has been described in the last decade. Various clinical applications have been found to provide hemithorax analgesia.
- Conditions
- Anesthesia, Postoperative Pain, Arrhythmias, Cardiac
- Trial name
- NCT06449599
- Testing
- ultrasound, parenteral local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Istanbul University - Cerrahpasa
Musculoskeletal Disorder, Pain Management
Safety & Efficacy of Nuberol Forte® in Pain Management
The global prevalence of Musculoskeletal disorders (MSD) ranges from 14% to as high as 42%. In addition WHO also estimates that 40% of people over the age of 60 years suffer from MSD and about 80% of the people have had low back…
- Trial name
- NFORT-EFFECT (NCT04765787)
- Testing
- Combination of Paracetamol 650mg + Orphenadrine 50mg
- Where
- 3 sites in Pakistan
- Volunteers
- 399 people
- Sponsor
- The Searle Company Limited Pakistan
Myocardial Infarction, Arthritis
Mechanisms of Action of Acetaminophen
This research study investigates whether the ability of aspirin to reduce the risk of heart attacks may be diminished by the administration of acetaminophen.
- Trial name
- NCT00646906
- Testing
- Aspirin First, Aspirin Last, Acetaminophen 1000 mg/d
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Renal Function After Partial Nephrectomy
PaNeX: Partial Nephrectomy Under Xenon
Purpose of this study is to determine whether Xenon - as compared to Isoflurane - shows a nephroprotection after partial nephrectomy.
- Trial name
- PaNeX (NCT01839084)
- Testing
- Xenon, Isoflurane
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- RWTH Aachen University
Prostate Cancer
Postoperative Pain Control for Prostatectomy
The researchers propose to investigate a relatively new anesthetic procedure, in order to maximize patient comfort and minimize the use of narcotics after a radical prostatectomy.
- Trial name
- TAP (NCT00913068)
- Testing
- Transverse Abdominal Plan (TAP), standard post op pain control
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Nova Scotia Health Authority
Breast Cancer Female, Postoperative Pain
Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study
Breast cancer is one of the most common types of cancer among women worldwide. (1) Breast-conserving surgery or mastectomy is indicated for the majority of patients with this type of cancer.
- Conditions
- Breast Cancer Female, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT04875559
- Testing
- Standardised multimodal pain treatment regimen
- Where
- Denmark
- Volunteers
- 236 people
- Sponsor
- Zealand University Hospital
Preoperative Anxiety, Postoperative Delirium
Preoperative Anxiety and Preemptive Analgesia on Postoperative Delirium in Adenotonsillectomy Surgery
The effects of preoperative anxiety and preemptive analgesia on PAED in children undergoing adenotonsillectomy surgery.
- Trial name
- NCT05802082
- Testing
- The Modified Yale Preoperative Anxiety Scale (m-YPAS) of children
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Zonguldak Bulent Ecevit University
Herpes Simplex Virus Infection
Oral and Perioral Herpes Simplex Virus Infection Type I in a Five-month-old Infant: A Case Report
A five-month-old healthy girl who presented with painful herpetic gingivostomatitis and perioral vesicles.
- Trial name
- NCT04713423
- Testing
- Diagnosis and treatment of the case
- Where
- Saudi Arabia
- Volunteers
- 1 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Leukemia, Acute Myelogenous (AML), Leukemia, Acute Lymphocytic (ALL)
Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood
Background: Most patients with acute lymphoblastic leukemia (ALL) and many patients with acute myelogenous leukemia (AML), chronic myelogenous leukemia (CML) and non-Hodgkin's lymphoma (NHL) have a protein called Wilm's Tumor 1…
- Conditions
- Leukemia, Acute Myelogenous (AML), Leukemia, Acute Lymphocytic (ALL), Leukemia, Chronic Myelogenous (CML), Myelodysplastic Syndrome (MDS)
- Trial name
- NCT00923910
- Testing
- WT1 Peptide-Pulsed Dendritic Cells, Donor Lymphocytes, IL-4
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Cancer Institute (NCI)
Perineal Tear, Perineal Laceration (Obstetric)
Comparison Between Rectal Suppository Acetaminophen and Diclofenac Sodium as Analgesia for Postpartum Perineal Tear
To assess the prevalence of pain score for perineum pain following childbirth followed by phase 2 study to assess the analgesic effectiveness of acetaminophen and diclofenac rectal suppository in postpartum perineum pain…
- Trial name
- SuPPerP (NCT03041779)
- Testing
- Diclofenac Sodium 50Mg Suppository, Paracetamol 500Mg Suppository
- Volunteers
- 909 people
- Sponsor
- Clinical Research Centre, Malaysia
Fatigue, Depression, Anxiety
Fatigue As a Late Effect in Breast Cancer Survivors - is Acupuncture a Treatment Option?
The success of treatment of breast cancer has improved, hence the prevalence of survivors have increased. However, experienced late effects from the cancer itself or from cancer treatment is substantial.
- Conditions
- Fatigue, Depression, Anxiety, Insomnia, Hot Flashes
- Trial name
- NCT04418115
- Testing
- Acupuncture; based on Tradidtional Chinese Medicine
- Where
- Norway
- Volunteers
- 223 people
- Sponsor
- Kristiania University College
Lumbar Disc Herniation
Quadratus Lumborum Block for Lumbar Spinal Surgery
Spine surgery in thoracolumbar region is one of the most common surgeries performed for the treatment of leg and back pain. Pain management is especially important for these patients since chronic pain often occurs after surgery.
- Trial name
- NCT04981301
- Testing
- Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Postoperative Pain Management
Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery
Primary aim of this prospective, randomized, double-blind, placebo-controlled clinical trial is to compare the analgesic effects of IV ibuprofen and paracetamol on postoperative pain, and secondary aim is the effects on morphine…
- Trial name
- ibuprofen (NCT03437707)
- Testing
- Morphine Sulfate, Intravenous paracetamol, Intravenous ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Inonu University
Foot Deformity, Arthrodesis
Subtalar & Talonavicular Arthrodesis v.s Subtalar & Naviculocuniform Arthrodesis for Progressive Collapsing Foot Deformity
This study compares two surgical procedures for adults with painful, rigid progressive collapsing foot deformity, also known as rigid flatfoot, whose symptoms have persisted despite at least six months of nonsurgical treatment.
- Trial name
- NCT07878000
- Testing
- Subtalar and talonavicular arthrodesis, subtalar and naviculocuneiform arthrodesis
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Cairo University
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