Clinical trials: Paracetamol
Post Operative Analgesia, Tonsillectomy With or Without Adenoidectomy
Preoperative High-Dose Oral Paracetamol for Postoperative Analgesia in Children Undergoing Tonsillectomy"
This randomized clinical trial compares two different preoperative doses of oral paracetamol (acetaminophen) in children undergoing elective tonsillectomy.
- Trial name
- NCT07463482
- Testing
- Paracetamol (acetaminophen)
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Thammasat University
Pancreatic Cancer, Pain
Invasive Treatment of Pain Associated With Pancreatic Cancer on Different Levels of WHO Analgesic Ladder
Pancreatic cancer is a difficult to treat disease, mainly due to the fact that diagnosis is made usually in the late stage of this condition.
- Trial name
- NCT02424279
- Testing
- Splanchnicectomy
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Gdansk
Colonoscopy, Pain
Analysis of the Analgesic Mechanism of TENS-WAA During Non-anesthetized Colonoscopy Using EEG-fNIRS System
This study is a single-center, randomized controlled trial aiming to evaluate the analgesic mechanism of Transcutaneous Electrical Nerve Stimulation based on Wrist-Ankle Acupuncture (TENS-WAA) during unsedated colonoscopy using…
- Trial name
- NCT06813703
- Testing
- Using an electrical stimulation device to relieve pain during colonoscopy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of the Chinese People's Liberation Army Naval Medical University
Pain, Fever
Pharmacokinetics, -Dynamics and Safety of Intravenous Paracetamol in Neonates
The purpose of this study is triple, i.e. document single dose pharmacokinetics and -dynamics of intravenous paracetamol in preterm and term neonates after a loading dose (20 mg/kg iv bolus paracetamol), document multiple dose…
- Trial name
- PARANEO (NCT00969176)
- Testing
- paracetamol
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Thoracic Anesthesia, Geriatric Anesthesia
The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients
One lung ventilation (OLV) is commonly used in thoracic surgery. Although the lack of ventilation of the lung in the surgical area (independent lung) during OLV redirects pulmonary blood flow to the dependent lung, shunt…
- Conditions
- Thoracic Anesthesia, Geriatric Anesthesia, One Lung Ventillation (OLV), POCD - Postoperative Cognitive Dysfunction
- Trial name
- NCT07339124
- Testing
- Cognitive Remediation, Pain Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Upper Limb Function in Subacute Hemiparetic Stroke Patients
Effectiveness of TENs Combined With Task-Related Training on Upper Limb Function in Subacute Hemiparetic Stroke Patients
To study the effectiveness of transcutaneous electrical nerve stimulation (TENS) combined with occupational therapy on restoring the function of the weakened limb in subacute stroke patients.
- Trial name
- NCT06641518
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Thailand
- Volunteers
- 18 people
- Sponsor
- Mahidol University
Kidney Stones, Nephrolithiasis
Safety and Effectiveness of the Ultrasonic Propulsion of Kidney Stones
This study tests moving kidney stones using focused ultrasound (referred to as ultrasonic propulsion). The study includes multiple population groups to investigate the ability of our technology to: a) move stone fragments to a…
- Conditions
- Kidney Stones, Nephrolithiasis, Urolithiasis
- Trial name
- NCT02028559
- Testing
- Propulse 1 with C5-2 probe, Propulse 1 with SC-X probe
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- University of Washington
Accelerated Orthodontic Tooth Movement
Comparing MOP, Prostaglandin E1, and Calcitriol to Accelerate Orthodontic Tooth Movement
This study will compare the effects of MOP (micro-osteoperforation), prostaglandin E1, and calcitriol on the rate of orthodontic tooth movement.
- Trial name
- acceleration (NCT07842120)
- Testing
- PGE₁ (pharmacological) • Agent: Prostaglandin E1, Calcitriol (1,25-(OH)₂D₃) local injection • Agent: Calcitriol (1,25-(OH)₂D₃) Vitamin D3, microosteoperforation MOP (surgical)
- Where
- 2 sites in Iraq
- Volunteers
- 60 people
- Sponsor
- Ghufran Dhari Awad
NSAID, Pain Management
Pre-emptive Analgesics in Orthodontic Treatment
This study is designed to determine if the preemptive use of a combination of acetaminophen and ibuprofen is more effective in reducing pain following orthodontic tooth movement when compared to the use of acetaminophen and…
- Trial name
- NCT03523988
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Washington
Postoperative Pain, Laparoscopic Cholecystectomy
External Oblique Intercostal Block (EOICB) for Laparoscopic Cholecystectomy
This single-center, prospective, randomized controlled trial aims to compare the effects of paravertebral block (PVB), external oblique intercostal (EOI) block, and intravenous patient-controlled analgesia (PCA) with tramadol on…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy, Paravertebral Block, External Oblique Intercostal Plane Block
- Trial name
- NCT07241949
- Testing
- Paravertebral Block (PVB), External Oblique Intercostal Block (EOI Block), Tramadol IV Patient-Controlled Analgesia (PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people
- Sponsor
- Cukurova University
Cholecystitis
Prophylactic TAP Block in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the gold standard for cholelithiasis, yet postoperative pain remains a clinical challenge. Ultrasound-guided transversus abdominis plane (TAP) block has been proposed as an effective analgesic…
- Trial name
- NCT07871617
- Testing
- Analgesic, Analgesic transversus abdominal plane blockade (Bupivacaine)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo
Pain
ACL Repair and Multimodal Analgesia
This study will evaluate the effectiveness of an aggressive multimodal regimen versus standard multimodal for Anterior Cruciate Ligament (ACL) repair using hamstring graft for patients having surgery in our outpatient surgicenter.
- Trial name
- NCT01868425
- Testing
- multimodal:acetaminophen, gabapentin, ketamine, bupivacaine
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Wisconsin, Madison
Obesity, Postoperative Pain
Laparoscopic Bariatric Surgery and Erector Spinae Plane Block
The aim of the study is to evaluate the effect of erector spinae plane (ESP) block on postoperative analgesic consumption in patients undergoing laparoscopic bariatric surgery
- Conditions
- Obesity, Postoperative Pain, Bariatric Surgery
- Trial name
- NCT04189289
- Testing
- ESP block group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Antalya Training and Research Hospital
Ankle Sprains
A Mobile Recovery Guidance App for Children and Young Adults With Acute Ankle Inversion Injuries
Ankle sprains are the most common musculoskeletal complaint of children presenting to the emergency department (ED). Healing can often be protracted, leading to prolonged pain, missed school and work, and delayed return to a…
- Trial name
- SPRAIN (NCT05785533)
- Testing
- Smartphone App, Standard of Care
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Naveen Poonai
Hip Fracture
Pain Control in Elderly Hip Fracture Patients: Is Intravenous Acetaminophen Superior to Oral Administration?
The primary objective is to determine if intravenous acetaminophen decreases pain scores and the amount of morphine equivalence received as compared to oral acetaminophen in patients greater than 65 years old after sustaining a…
- Trial name
- NCT02774148
- Testing
- IV Acetaminophen, PO Acetaminophen
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Corewell Health West
Postoperative Pain, Acute
Comparative Study Between Caudal Epidural Block and Bilateral Erector Spinae Plane Block in Lumbosacral Spine Surgeries.
It is widely believed that major lumbosacral spine surgeries are associated with severe postoperative pain that may delay the functional recovery of the patient.
- Trial name
- NCT05729308
- Testing
- caudal epidural block, bilateral erector spinae plane block, general anesthesia with intravenous analgesia.
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Open Heart Surgery, Postoperative Pain
Postoperative Pain Alleviation in Open Heart Surgery
Effective pain relief after cardiac surgery has assumed importance with the introduction of fast track discharge protocols that requires early weaning from mechanical ventilation.
- Trial name
- NCT03106818
- Testing
- bupivacain with magnesium sulphate, Bupivacaine only, conventional
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Cesarean Section
Comparison of Modified Perichondral Approach Thoracoabdominal Nerve Block and Transversus Abdominal Plane Block in Analgesia Management Following Caesarean Section Surgery
Cesarean section (CS) is one of the most frequently performed surgical procedures in the World. Moderate to severe postoperative pain occurs in a significant proportion of women after cesarean surgery.
- Trial name
- NCT06185725
- Testing
- Modified Perichondral Approach Thoracoabdominal Nerve Block, Transversus Abdominal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Shoulder Pain
Multimodal Analgesia With NSAID vs. Narcotics Alone After Shoulder Instability Surgery
This will be a single-center, prospective observational study. The study will compare post- operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and Percocet…
- Trial name
- NCT04018768
- Testing
- ibuprofen 600 mg, Oxycodone/acetaminophen (Percocet) 5 mg/325
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- NYU Langone Health
Migraine
A Study of Rizatriptan Co-Administered With Acetaminophen for the Treatment of Acute Migraine
The purpose of this study is to test an experimental drug combination of two medications currently approved by the Food and Drug Administration (FDA) for migraine headache or other pain.
- Trial name
- NCT00300924
- Testing
- Rizatriptan co-administered with Acetaminophen
- Where
- 7 sites in United States
- Volunteers
- 200 people
- Sponsor
- Diamond Headache Clinic
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.