Clinical trials: Physical Therapy
Dry Needling Technique, Neck Pain Musculoskeletal
How Dry Needling at the Neck Affects Shoulder Movement, Strength, Pain, and Shoulder Circulation
Segmental facilitation, originally proposed by Korr in the 1950s, suggests that certain spinal segments can become hyperexcitable, leading to chronic pain development.
- Conditions
- Dry Needling Technique, Neck Pain Musculoskeletal, Shoulder Pain, Neck Pain
- Trial name
- NCT06705634
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Texas Woman's University
Orthodontic Appliances, Oral Health Training
Effects Of Training On Brushing Behavior
This study is a single-blind randomized controlled trial on fixed orthodontic appliance candidates (n = 90) assigned into a control group (n = 30) and two different study groups (n = 30 in each).
- Conditions
- Orthodontic Appliances, Oral Health Training, Oral Hygiene
- Trial name
- NCT04018534
- Testing
- Standard Verbal/Written Education, Video Assisted Education, Hands-on Training
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Okan University
Stroke
A Mobile Brain/Body Imaging Platform for the Assessment and Optimization of Post-stroke Overground Robotic Gait Treatments
The study aims to identify neural biomarkers that can be used to monitor the recovery of locomotion and movement of post-stroke patients, both in natural settings and with enriched treatment using robotic device.
- Trial name
- COBI (NCT07510633)
- Testing
- overground wearable robotic device
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Franco Molteni
Pain, Chronic Pain
Exploring the Feasibility of Using Virtual Reality as an Educational Tool in Chronic Pain Rehabilitation
Introduction: Chronic pain significantly impacts quality of life and requires comprehensive management strategies. Traditional pain education programs are beneficial but often require significant and prolonged patient engagement.
- Conditions
- Pain, Chronic Pain, Chronic Pain (Back / Neck), Adults
- Trial name
- NCT07434804
- Testing
- 6-Week Virtual reality-delivered pain science education and behavioural pain management program
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- University College Dublin
Carpal Tunnel Syndrome
Effectiveness of Carpal Ligament Self-myofascial Stretching in Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS), also known as median mononeuropathy, occurs when the median nerve is squeezed or compressed as it travels through the carpal tunnel at the wrist. It is common in the age group of 40-60 years.
- Trial name
- NCT06229249
- Testing
- Carpal ligament self-myofascial stretching, Conventional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Saud University
Stage IB Lung Non-Small Cell Carcinoma AJCC v7, Stage II Lung Non-Small Cell Cancer AJCC v7
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)
This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery.
- Conditions
- Stage IB Lung Non-Small Cell Carcinoma AJCC v7, Stage II Lung Non-Small Cell Cancer AJCC v7, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8
- Trial name
- NCT02194738
- Testing
- Biospecimen Collection, Carboplatin, Cisplatin
- Where
- 1,660 sites in United States, Guam and 1 more
- Volunteers
- 7,458 people
- Sponsor
- National Cancer Institute (NCI)
Gastric Adenocarcinoma
ITACA-S2 (Intergroup Trial in Adjuvant Chemotherapy for Adenocarcinoma of the Stomach)
The study addresses two primary questions, according to its factorial design: to compare the efficacy in terms of overall survival (OS) of a peri-operative vs.
- Trial name
- ITACA-S2 (NCT01989858)
- Testing
- peri-operative cht, post-operative CHT, peri-operative cht + post-operative cht-rtx
- Where
- 32 sites in Italy
- Volunteers
- 1,180 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Cystic Fibrosis
Comparison of Airway Clearance Efficacy of Two High Frequency Chest Wall Oscillation (HFCWO) Devices in Cystic Fibrosis
Patients with cystic fibrosis (CF) must perform daily bronchial drainage therapy (BD) to keep their airways clear of secretions.
- Trial name
- NCT00308958
- Testing
- High frequency chest wall oscillator
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Vestibular Rehabilitation
Effect of Platform Swing Walkway on Locomotor Behavior in Diplegic Children
Locomotor activity is accompanied by a number of sensory stimuli: visual, auditory, olfactory, vestibular, and somatosensory. When improving motor skills, incorporating postural reflexes, creating synchronized eye movements, and…
- Trial name
- NCT04246658
- Testing
- conventional physical therapy program, gait training on platform swing walkway
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- hanaa mohsen
Stroke, Acute
Hemodynamic Response and Motor Functions Following Transcranial Direct Current Stimulation in Acute Stroke
The aim of the present study is to evaluate the possible effect of using dual-tDCS applied before conventional physical therapy on motor functions and hemodynamic response
- Trial name
- NCT04051658
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Mahidol University
Low Back Pain
Pilot Study on Digitally Supported Home Exercises for the Management of Unspecific Low Back Pain.
The overall purpose of the study is to investigate effect of Digitally Supported Home Exercises (DSHE) in different groups for which digitally supported interventions could be beneficial.
- Trial name
- NCT04364243
- Testing
- Digitally supported home exercises
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Preoperative Aerobic Training, Solid Tumors
Study of the Effects of Pre-surgical Aerobic Exercise on Patients With Solid Tumors
The purpose of this study is to find the safest level of aerobic training for people about to undergo surgery for their cancer, and to learn what effects, if any, aerobic exercise has on these patients and the outcomes of their…
- Trial name
- NCT03813615
- Testing
- treadmill walking (Proof-of-Concept), treadmill walking Dose-Finding / Escalation
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
COPD, Non-invasive Ventilation
NIV Reduces CBF in COPD Patients Without Cognitive Function
Objectives: Investigate the acute NIV effects on CBF and cognitive functions in COPD patients. Methods: Nine non-hypercapnic stable COPD subjects (FEV1/FVC < lower limit of normal) and twelve healthy controls were enrolled.
- Conditions
- COPD, Non-invasive Ventilation, Cognitive Impairment, Cerebral Blood Flow
- Trial name
- NCT03149835
- Testing
- Non-invasive ventilation
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Ceara
Mouth, Edentulous
Conventionally vs. Digitally Fabricated Complete Dentures: Clinical Treatment Outcome Differences
Purpose: To compare complete denture outcomes between conventional and digital denture fabrication processes. Participants: Sixteen edentulous adult patients in the University of North Carolina School of Dentistry Student Clinic…
- Trial name
- NCT02521935
- Testing
- Complete traditional dentures, Complete CADCAM dentures
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Melanoma, Non-small Cell Lung Cancer
Pembrolizumab-PET Imaging
This is a two center, single arm, investigator sponsored trial (IST) with the PET tracer 89Zr-pembrolizumab to evaluate in vivo whole body distribution of 89Zr-Pembrolizumab in a registered indication: locally advanced metastatic…
- Trial name
- NCT02760225
- Testing
- 89Zr-Pembrolizumab, 89Zr-Pembrolizumab PET
- Where
- 2 sites in Netherlands
- Volunteers
- 18 people
- Sponsor
- University Medical Center Groningen
Adhesive Capsulitis
Education-based Physical Therapy Approach for Adhesive Capsulitis
This study aims, by means of a randomized control trial, to investigate which treatment method (corticoid injection + physiotherapy with a focus on manual therapy and home-exercises versus corticosteroid injection + physiotherapy…
- Trial name
- NCT03245476
- Testing
- Physical therapy focus on manual therapy and home-exercises, Physical therapy focus on education and supported home exercises
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Hasselt University
Metastatic Prostate Cancer
68Ga-PSMA PET/CT for Ra223 Assessment
Primary objective: i.The primary objective is to compare the diagnostic positivity in progression of 68Ga-PSMA PET and Bone scan.
- Trial name
- NCT04951817
- Testing
- Ga-68 PSMA ligand
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- Chang Gung Memorial Hospital
Cataract
Evaluation of Therapeutic Strategies in Pediatric Cataract Surgery
The purpose of this observational study is to assess the therapeutic strategies in the treatment of pediatric cataracts.
- Trial name
- EP3C (NCT02253017)
- Testing
- Children operated on for cataract
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Locally Advanced Bladder Carcinoma, Metastatic Bladder Carcinoma
An Education and Navigation Support Tool to Improve Participation in Care Coordination Among Patients With Locally Advanced, Metastatic and Unresectable Bladder Cancer and Their Caregivers
This clinical trial evaluates the impact of an education and navigation support tool (ENST) on patient and caregiver participation in care coordination for bladder cancer that has spread to nearby tissue or lymph nodes (locally…
- Conditions
- Locally Advanced Bladder Carcinoma, Metastatic Bladder Carcinoma, Stage III Bladder Cancer AJCC v8, Stage IV Bladder Cancer AJCC v8
- Trial name
- NCT06414317
- Testing
- Assessment of Distress, Consultation Visit, Nutritional Assessment
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter randomized withdrawal trial in patients with major…
- Trial name
- CLARITY (NCT07484217)
- Testing
- Solriamfetol 150 MG
- Where
- 40 sites in United States
- Volunteers
- 508 people
- Sponsor
- Axsome Therapeutics, Inc.
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