Clinical trials: Physical Therapy
Syncope, Vasovagal, Postural Orthostatic Tachycardia Syndrome
Paediatric Syncope in the Emergency Department
The investigators will assess the efficacy of clinically recommended counterpressure maneuvers (CPM) in preventing syncope for paediatric patients.
- Conditions
- Syncope, Vasovagal, Postural Orthostatic Tachycardia Syndrome, Orthostatic Intolerance
- Trial name
- DETECT-ED (NCT05555771)
- Testing
- Counterpressure Maneuvers, Usual Care
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Dr. Victoria Claydon
Hyperkyphosis
Physical Therapy Exercises in Hyperkyphosis
This proposal is a single center preliminary prospective cohort trial that evaluates patients with hyperkyphosis. Participants will receive physical therapy exercises and be followed for the above outcome measures over time.
- Trial name
- NCT03212664
- Testing
- exercise
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Lung Cancer, Breast Cancer
Evaluation of Skin Health and QoL in Pts Receiving Anti-PD1/PDL1/CTLA4 or CDK Inhibitors.
The study aim to investigate the relationship between cutaneous adverse events and quality of life in patients taking immune check point inhibitor or cyclin-dependent kinase (CDK) 4 and 6 inhibitors by two steps.
- Conditions
- Lung Cancer, Breast Cancer, Kidney Cancer, Bladder Cancer
- Trial name
- SkinHealth (NCT05878964)
- Testing
- EQ-5D-5L questionnaire, FACT-G (Functional Assessment of Cancer Therapy - General), FACT-EGFRI-18 (Functional Assessment of Cancer Therapy - Epidermal Growth Factor Inhibitors 18 Item)
- Where
- Italy
- Volunteers
- 420 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
High Bleeding Risk Patients, DAPT(Dual Antiplatelet Therapy)
OCT-based DAPT Cessation in HBR Patients
This study investigates whether patients with diabetes mellitus (DM) and a high risk of bleeding can safely stop dual antiplatelet therapy (DAPT) earlier than usual after receiving a special type of stent called a polymer-free…
- Conditions
- High Bleeding Risk Patients, DAPT(Dual Antiplatelet Therapy), Coronary Artery Disease, Diabetes Mellitus
- Trial name
- NCT07238764
- Testing
- Optical Coherence Tomography-based early DAPT discontinuation
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Immune Thrombocytopenia (ITP)
A Clinical Study Evaluating the Safety and Preliminary Efficacy of Universal Allogeneic CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C)in Patients With Refractory Primary Immune Thrombocytopenia
This is an investigator-initiated trial to evaluate the safety and efficacy of universal allogeneic anti-CD19/BCMA CAR T-cells(QT-019C) in Patients With Refractory Primary Immune Thrombocytopenia.
- Trial name
- NCT07416032
- Testing
- QT-019C
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Chronic Obstructive Pulmonary Disease
Balance Training in Patients With Chronic Obstructive Pulmonary Disease (COPD)
A growing body of evidence suggests that individuals with chronic lung disease have important deficits in balance control that may be associated with an increased risk of falls.
- Trial name
- NCT01424098
- Testing
- Balance training program
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Roger Goldstein
Asthma
Recombinant Human IL-4 Receptor Used in Treatment of Asthma
The purpose is to measure the effectiveness of recombinant human interleukin-4 receptor (IL-4R) in treating asthma. Asthma can be caused by the allergic response from breathing in certain irritants.
- Trial name
- NCT00017693
- Testing
- Recombinant human soluble IL-4 receptor
- Volunteers
- 62 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Concussion Post Syndrome
Auditory Slow Wave Enhancement After Concussion
The prevalence of a traumatic brain injury (TBI) in children and adolescents is around 30% with 70-90% being classified as mild (concussion).
- Trial name
- NCT04770116
- Testing
- Auditory Stimulation
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Cervical Spondylosis, Neck Pain
Efficacy of Acupuncture at Lieque (LU7) for Neck Pain in Cervical Spondylosis
Cervical spondylosis is a common degenerative disorder of the cervical spine that often leads to chronic neck pain, stiffness, and reduced daily functioning.
- Trial name
- NCT07151404
- Testing
- Acupuncture at LU7 (Lieque) + Electroacupuncture, Electroacupuncture Only
- Where
- Vietnam
- Volunteers
- 130 people
- Sponsor
- Nguyen Ngoc Doan Thuy
Abdominal Surgery
Pre-operative and Post-operative Physiotherapy in Children With Abdominal Surgery
The study will be conducted in a pediatric surgery ward, department of pediatrics. Children between the ages of 5 to 17 years who underwent for abdominal surgery will be recruited by simple random sampling.
- Trial name
- NCT03543904
- Testing
- Pre-operative physiotherapy education, Post-operative physiotherapy intervention
- Where
- India
- Volunteers
- 21 people
- Sponsor
- Asir John Samuel
Heart Failure
Patient-Reported Outcome Measurement in Heart Failure Clinic
This is a randomized study evaluating the effect of routinely collecting a standardized questionnaire of heart failure health status during heart failure clinic visits.
- Trial name
- PRO-HF (NCT04164004)
- Testing
- Kansas City Cardiomyopathy Questionnaire-12
- Where
- United States
- Volunteers
- 1,249 people
- Sponsor
- Stanford University
Ovarian Neoplasms, Colorectal Neoplasms
An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation
Doctors will take some tissue from the tissue removed during surgery in order to study how the blood vessels of the tumor respond to radiation therapy.
- Conditions
- Ovarian Neoplasms, Colorectal Neoplasms, Melanoma, Small Cell Lung Cancer
- Trial name
- NCT00132704
- Testing
- Ionizing radiation (IR) therapy, Ionizing radiation (IR)
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Atrial Fibrillation
Assessment of Thrombotic Status in Patients With Atrial Fibrillation
Investigators will assess the impact of treatments for atrial fibrillation on participant's thrombotic status
- Trial name
- NCT02583971
- Volunteers
- 500 people
- Sponsor
- East and North Hertfordshire NHS Trust
Rheumatic Diseases, Temporomandibular Joint Dysfunction
Treatment in Individuals With Rheumatoid Arthritis Who Have Temporomandibular Joint Dysfunction
This study was conducted to investigate the effect of manual therapy applications on pain, range of motion and joint position sense in individuals with rheumatoid arthritis who have temporomandibular joint dysfunction.
- Conditions
- Rheumatic Diseases, Temporomandibular Joint Dysfunction, Manuel Therapy
- Trial name
- NCT07171671
- Testing
- exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sanko University
Pain
Pain Assessment During General Anesthesia
During general anesthesia, two treatments are used : hypnotic and opioid treatment. Opioid treatment is used for pain assessment.
- Trial name
- DOLANS (NCT01303471)
- Testing
- opioid (remifentanyl)
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Grief
A Grief Support App for Adults Experiencing Bereavement
Losing a loved one is a difficult experience. Some people may require psychological support, but even for those who do not, grief can often feel overwhelming.
- Trial name
- NCT07862244
- Testing
- Self-guided grief app (Daybreak), Waiting list
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Breast Cancer
FRAGRANCE Part A Safety: Study to Find a Genetic Signature of de Novo Resistance to Letrozole
Find a genetic signature of de novo resistance to letrozole in adjuvant breast cancer;
- Trial name
- NCT00199134
- Testing
- Letrozole
- Where
- Belgium
- Volunteers
- 49 people
- Sponsor
- Jules Bordet Institute
HIV, HIV-uninfected Children
A Cross Sectional Evaluation of the Development in Children Age 4 to 7 Infected or Exposed to HIV From the ANRS 12140 Cohort (Pediacam)
This study aims to perform a comprehensive neuro-cognitive evaluation of the 4-7 year old children from the Pediacam cohort (ANRS 12140 /12225, NCT02043418).
- Conditions
- HIV, HIV-uninfected Children, Children Exposed to HIV
- Trial name
- PediacamDEV (NCT02570334)
- Testing
- HIV-infected children initiated antiretroviral treatment within the first 7 months of life
- Where
- 3 sites in Cameroon
- Volunteers
- 400 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Chronic Conditions, Multiple
A Physiotherapy-led Disease-agnostic Telerehabilitation Programme for People With Chronic Health Conditions
This protocol outlines a planned mixed methods feasibility trial which will be conducted to examine the feasibility and acceptability of a physiotherapy-led exercise-based telerehabilitation programme for groups of people with…
- Trial name
- NCT06388499
- Testing
- TECC (Telerehabilitation and Exercise for Chronic Conditions)
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University of Limerick
Pulmonary Hypertension
Inspiratory Muscle Training in Pulmonary Hypertension
The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.
- Trial name
- NCT03385733
- Testing
- inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University
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