Clinical trials: Physical Therapy
Metastatic Renal Cell Carcinoma, Metastatic Urothelial Carcinoma
A Phase II Randomized Trial of Immunotherapy Plus Radiotherapy in Metastatic Genitourinary Cancers
The trial is open to patients who have metastatic renal cell carcinoma/urothelial (bladder) carcinoma with at least 2 measurable sites of disease.
- Trial name
- NCT03115801
- Testing
- Nivolumab, Atezolizumab, Radiation & immunotherapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Weill Medical College of Cornell University
Infant Development, Hemiplegia
CIMT and taVNS for Hemiplegia in Infants
Newborns who are born premature or suffer brain injury at birth are at risk for motor problems that may cause weakness in reaching and grasping on one side of the body.
- Conditions
- Infant Development, Hemiplegia, Constraint Induced Movement Therapy
- Trial name
- NCT05101707
- Testing
- transcutaneous auricular vagus nerve stimulation, Constraint induced movement therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical University of South Carolina
Pulmonary Disease, Chronic Obstructive
Assessment of Physical Functioning and Handling of Spiolto Respimat in Patients With COPD (OTIVACTO)
The primary objective of this Non Interventional Study is to measure changes in physical functioning, a surrogate for physical activity and exercise capacity, in COPD patients on treatment with Spiolto® Respimat® in routine daily…
- Trial name
- NCT02720757
- Testing
- Spiolto Respimat
- Where
- 6 sites in Belgium, Denmark and 4 more
- Volunteers
- 132 people
- Sponsor
- Boehringer Ingelheim
Adolescent Idiopathic Scoliosis
Application of Virtual Reality in Post-Operative Recovery of a Pediatric Scoliosis Patient Population
The purpose of this study is to assess the effect of virtual reality on subjective post-operative pain, total inpatient narcotic administration, and mobilization with physical therapy in pediatric patients who have undergone…
- Trial name
- NCT06101264
- Testing
- Control, Virtual Reality
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Connecticut Children's Medical Center
Dental Caries
Decision Aids for the Management of Suspicious Occlusal Caries Lesions
The study will determine whether clinicians who use a diagnostic device treat suspicious occlusal carious lesions (SOCL) surgically more often, with the same frequency, or less frequently, than dentists not relying on a…
- Trial name
- SOCL (NCT02340767)
- Testing
- Spectra Device, DIAGNOdent
- Where
- 6 sites in United States
- Volunteers
- 3,085 people, healthy volunteers welcome
- Sponsor
- The National Dental Practice-Based Research Network
Persistent Pregnancy of Unknown Location, Ectopic Pregnancy
RCT for Women With a Persisting Pregnancy of Unknown Location
This is a randomized controlled trial to compare three currently available management strategies for women with a persisting pregnancy of unknown location (PPUL), which makes them at-risk for ectopic pregnancy.
- Trial name
- PPUL (NCT01800162)
- Testing
- Methotrexate, Uterine Evacuation, Expectant Management
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Aphasia, Language Disorders
Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis
The purpose of this investigation is to further develop and test a treatment for word-finding problems in aphasia. The treatment is designed to strengthen meaning associations within categories of words (e.g., animals, tools…
- Conditions
- Aphasia, Language Disorders, Speech Disorders
- Trial name
- NCT00125242
- Testing
- Semantic Feature Analysis (SFA)Training
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Chronic Obstructive Pulmonary Disease
Effect of Bronchodilation on Cycle vs Treadmill Exercise Endurance Time in COPD
Previous studies suggest that treadmill exercise may be a more relevant exercise stimulus than the cycle ergometer to demonstrate benefits with bronchodilator therapy in patients with COPD.
- Trial name
- ARFEET (NCT00754546)
- Testing
- Arformoterol tartrate, Treadmill Exercise, Cycle Exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Multiple Myeloma
Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma
This randomized phase III trial studies melphalan and prednisone with thalidomide to see how well it works compared to melphalan and prednisone together with lenalidomide in treating patients with newly diagnosed multiple…
- Trial name
- NCT00602641
- Testing
- Laboratory Biomarker Analysis, Lenalidomide, Melphalan
- Where
- 391 sites in United States, Israel
- Volunteers
- 306 people
- Sponsor
- National Cancer Institute (NCI)
Aging, Sedentary Lifestyle
Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age
This 2-site randomized double blinded controlled trial is to confirm and more definitively clarify the impact of a 12-week course of nitrite versus placebo on mitochondrial bioenergetics in older sedentary adults.
- Conditions
- Aging, Sedentary Lifestyle, Frailty
- Trial name
- Nitrite (NCT04405180)
- Testing
- 20mg sodium nitrite tid
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Gladwin, Mark, MD
Atrial Fibrillation
Assessment of Safety and Effectiveness in Treatment Management of Atrial Fibrillation With the BWI IRE Ablation System
To demonstrate the safety and 12-month effectiveness of the VARIPULSE™ Catheter when used in conjunction with the TRUPULSE™ Generator for pulmonary vein isolation (PVI) in the treatment of subjects with symptomatic paroxysmal…
- Trial name
- AdmIRE (NCT05293639)
- Testing
- Pulse Field Ablation
- Where
- 30 sites in United States
- Volunteers
- 362 people
- Sponsor
- Biosense Webster, Inc.
Vitamin D Deficiency
The Effect of Oral Vitamin D Versus Narrow-Band UV-B Exposure on the Lipid Profile
Participants in this study will be randomized to receive either oral vitamin D pills OR ultraviolet light treatment. The investigators will compare how these two methods of raising vitamin D levels will affect cholesterol levels.
- Trial name
- NCT01688102
- Testing
- Oral Vitamin D3, Ultraviolet Light
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Prostate Cancer
Hormone Suppression and Radiation Therapy for 6 Months With/Without Docetaxel for High Risk Prostate Cancer
This randomized study is looking at the benefits of using docetaxel (chemotherapy) added to one of the standard treatments (radiation and hormones) for men with high-risk prostate cancer.
- Trial name
- NCT00116142
- Testing
- Docetaxel, Androgen Hormonal Suppression and Radiation, Androgen Suppression Therapy and Radiation Therapy
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Dana-Farber Cancer Institute
Stroke, Acute
The Intravascular Cooling in the Treatment of Stroke 2/3 Trial
The purpose of this trial is to determine whether the combination of thrombolysis and hypothermia is superior to thrombolysis alone for the treatment of acute ischemic stroke.
- Trial name
- ICTuS2/3 (NCT01123161)
- Testing
- hypothermia and anti-shivering treatment, Group1: IV t-PA and normothermia
- Where
- 31 sites in United States, Austria and 1 more
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Adenosine Deaminase Severe Combined Immunodeficiency
Registry Study of Revcovi Treatment in Patients With ADA-SCID
This registry study is being conducted in patients with adenosine deaminase severe combined immune deficiency (ADA-SCID) who require enzyme replacement therapy (ERT) treatment with Revcovi.
- Trial name
- NCT03878069
- Testing
- elapegademase-lvlr
- Where
- 14 sites in United States
- Volunteers
- 32 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Merkel Cell Polyomavirus Infection, Stage IV Merkel Cell Carcinoma AJCC v7
Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma
This phase I/II trial studies the side effects and how well localized radiation therapy or recombinant interferon beta and avelumab with or without cellular adoptive immunotherapy works in treating patients with Merkel cell…
- Trial name
- NCT02584829
- Testing
- Avelumab, Laboratory Biomarker Analysis, MCPyV TAg-specific Polyclonal Autologous CD8-positive T Cells
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Fred Hutchinson Cancer Center
Dyslipidemia
Study of Lipid Control in Hyperlipidemic Participants (MK-0653-179)
This study is being done to see whether dietary and medicinal measures compliant with hyperlipidemia treatment guidelines will result in achieving target lipid values and to evaluate the total risk of cardiovascular disease in…
- Trial name
- NCT01436253
- Testing
- Lifestyle Changes, Hypolipemics
- Volunteers
- 2,196 people
- Sponsor
- Organon and Co
Binge Eating
Binge Eating Syndrome Treatment for Older Women (BESTOW)
Twenty women, ages 60 or older, will be consented and enrolled in a single-arm, pilot implementation trial of the age-tailored cognitive-behavioral based BE intervention.
- Trial name
- BESTOW (NCT05806788)
- Testing
- Binge Eating Syndrome Treatment (BESTOW)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Muscle Loss
Enhanced Bioscaffold for Volumetric Muscle Loss
This is a prospective, single center study conducted at the University of Pittsburgh designed to test the applicability and utility of XenMatrix™ AB Surgical Graft in the restoration of function in the setting of volumetric…
- Trial name
- MTEC-VML (NCT04051242)
- Testing
- XenMatrix™ AB Surgical Graft
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- J. Peter Rubin, MD
Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
The MOTION Study - Treatment of LSS With the MILD Procedure
Prospective, multicenter, randomized controlled clinical study examining functional improvement in lumbar spinal stenosis (LSS) patients with neurogenic claudication who are treated with the MILD procedure plus conventional…
- Trial name
- NCT03610737
- Testing
- MILD Procedure, Conventional Medical Management (CMM)
- Where
- 18 sites in United States
- Volunteers
- 155 people
- Sponsor
- Vertos Medical, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.