Clinical trials: Physical activity
Depressive Disorder
Combining Antidepressants and Attention Bias Modification in Depression
Background: Major depressive disorder (MDD) is a highly prevalent psychiatric condition associated with significant disability, mortality and economic burden.
- Trial name
- DEPTREAT (NCT05503966)
- Testing
- Attentional Bias Modification
- Where
- Norway
- Volunteers
- 246 people
- Sponsor
- University of Oslo
Diabetes Type 2
Safety Study of BMS-770767 in Subjects With Type 2 Diabetes
The purpose of this study is to determine if BMS-770767 is safe, well tolerated, measure its levels in the blood (pharmacokinetics), and measure the levels of chemicals (biomarkers) that may be affected by this drug…
- Trial name
- NCT01046422
- Testing
- BMS-770767, Metformin
- Where
- 18 sites in United States, Australia and 2 more
- Volunteers
- 76 people
- Sponsor
- Bristol-Myers Squibb
Arteriovenous Fistula Thrombosis, Arteriovenous Fistula Stenosis
Isometric Preoperative Exercise on Autologous Arteriovenous Fistulas. Randomized Clinical Trial
A good vascular access (VA) is vital for hemodialysis (HD) patients. The start of HD with autologous arteriovenous fistula (AVF) means higher survival, lower sanitary costs and complications.
- Trial name
- PHYSICALFAV (NCT03213756)
- Testing
- Isometric exercises using Hand grip and elastic bands
- Where
- Spain
- Volunteers
- 138 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Healthy, Physiology
Assessment of the Changes in Cortical and Medullary Renal Blood Flow During Exercise in Healthy Subjects Using Contrast Enhanced Ultrasound
Renal parenchymal blood flow can be divided in cortical and medullary blood flow. Changes and factors affecting renal medullary blood flow have not been studied in detail previously as investigators/doctors did not have tools to…
- Trial name
- NCT02672722
- Testing
- Definity, Exercise, Kidney Ultrasound
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Educational Problems, Respiratory Muscle
Educational Programme in Diaphragm Ultrasonographic Assessment
Diaphragm ultrasound non-invasively explores the diaphragm function and it can be useful in several clinical situations. Diaphragm ultrasound is able to evaluate the cranio-caudal displacement of the diaphragm and its thickening…
- Conditions
- Educational Problems, Respiratory Muscle, Diaphragm Disease
- Trial name
- NCT03704129
- Testing
- Tutor
- Where
- Italy
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Paolo Navalesi
Anxiety, Exercises Therapy
Progressive Relaxation Exercises on Anxiety Levels
The research will be conducted to determine the effect of progressive relaxation exercises on the anxiety level of patients who have had total knee replacement surgery.
- Conditions
- Anxiety, Exercises Therapy, Total Knee Replacement Surgery
- Trial name
- NCT06676202
- Testing
- Progressive Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Ankle Fractures, Surgery
Immediate Weight-Bearing Ankle Study
This single-centre historical control group comparative study will compare outcomes of surgically-treated rotational ankle fractures and the current routine practice of early protected weightbearing and range of motion with…
- Trial name
- NCT03032653
- Testing
- Late Rehabilitation, Early Rehabilitation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Fraser Orthopaedic Research Society
BCLC Stage C HCC, CP-B Liver Cirrhosis
Sorafenib PK in Patients With Advanced HCC and Child-Pugh B
Sorafenib has proven efficacy in advanced hepatocellular carcinoma (HCC). Most patients with HCC have impaired liver function due to underlying liver cirrhosis.
- Trial name
- SORBE (NCT04051853)
- Testing
- Sorafenib, Midazolam clearance test, CYP cocktail clearance test
- Where
- Netherlands
- Volunteers
- 5 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Crohn Disease Haemorrhagic Rectocolitis
Study of the Impact of a Physical Activity Programme on the Quality of Life of Patients With Inflammatory Bowel Disease
Regular physical activity at a mild to moderate intensity can control inflammation in general and intestinal inflammation in particular during IBD.
- Trial name
- APMICI (NCT05099653)
- Testing
- physical activity
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Raincy Montfermeil Hospital Group
Knee Osteoarthritis
Tai Chi Mind-Body Therapy for Knee Osteoarthritis
The purpose of this study was to compare the safety and effectiveness of Tai Chi with an Attention Control intervention consisting of a stretching and wellness education program involving 40 patients with osteoarthritis (OA) of…
- Trial name
- NCT00362453
- Testing
- Tai Chi versus Attention Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Atrial Fibrillation
Effects of Detraining in Endurance Athletes With Atrial Fibrillation
Atrial fibrillation (AF) affects more than 43 million people worldwide, but specific exercise recommendations do not exist for this group of patients.
- Trial name
- NEXAF (NCT04991337)
- Testing
- Detraining group, Control group
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Vestre Viken Hospital Trust
COPD Exacerbation
Enhancing Muscle Function After Exacerbations of COPD to Limit Its Impact on Physical Activity Decline
Patients with COPD lose muscle strength during acute exacerbations of COPD (AECOPD) which interferes improving the recovery of physical activity (PA) after an AECOPD. Resistance training can reverse this process.
- Trial name
- NCT05233137
- Testing
- PA coaching, Exercise training
- Where
- 2 sites in Belgium
- Volunteers
- 86 people
- Sponsor
- KU Leuven
Major Depressive Disorder, Post-Traumatic Stress Disorder
Examination of Glutamate and mGluR5 in Psychiatric Disorders
This research study is designed to look at the involvement of the glutamate system in depression. Each subject will undergo a screening appointment to determine study eligibility.
- Conditions
- Major Depressive Disorder, Post-Traumatic Stress Disorder, Bipolar Disorder
- Trial name
- NCT02727972
- Testing
- Cognitive Testing, MRI, PET
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University
Chronic Kidney Disease
Exercise to Prevent Muscle Mass and Functional Loss in Elderly Dialysis Patients
The majority of individuals with advanced ESRD have reduced exercise capacity in part due to decreased muscle mass. This leads to a reduced ability to perform daily activities, a greater incidence of falls, and a reduced quality…
- Trial name
- PERFECT (NCT01990495)
- Testing
- Exercise training, Usual Care
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- VA Office of Research and Development
Thyroid Neoplasms
The Dose of Radioactive Iodine Needed to Ablate the Thyroid Remnant Left Behind After Thyroidectomy
The thyroid cells take up iodine, and radioactive iodine is commonly used to irradiate residual thyroid tissue and thyroid cancer following surgical removal of the thyroid gland (thyroidectomy).
- Trial name
- NCT00115895
- Testing
- Radioactive iodine
- Where
- Finland
- Volunteers
- 160 people
- Sponsor
- University of Helsinki
Dysphagia, Oropharyngeal, Stroke, Ischemic
Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke
This study will evaluate the effectiveness of conventional speech therapy associated with functional electrical stimulation in patients with dysphagia after ischemic stroke.
- Trial name
- NCT03649295
- Testing
- Functional Electrical Stimulation, Conventional Speech Therapy
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Hospital Geral de Fortaleza
HER2-expressing Cancers
A Study of Zanidatamab (ZW25) With Evorpacept (ALX148) in Patients With Advanced HER2-expressing Cancer
This study is being done to find out if zanidatamab when given with evorpacept (ALX148) is safe and can treat patients with advanced (locally advanced [inoperable] and/or metastatic) human epidermal growth factor receptor 2…
- Trial name
- NCT05027139
- Testing
- Zanidatamab, Evorpacept
- Where
- 11 sites in United States
- Volunteers
- 52 people
- Sponsor
- Jazz Pharmaceuticals
Breast Cancer
Adapted Physical Activity Effect on Aerobic Function and Fatigue at Home in Patients With Breast Cancer Treated in Adjuvant or Neoadjuvant Phase
Physical exercise has been identified as a major item of many chronic diseases and cancer rehabilitation. It contributes to an improvement in the quality of life and to a decrease in the current treatment side effects and…
- Trial name
- APAC (NCT01795612)
- Testing
- physical activity
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Limoges
Hypertension
An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Patients With Type II Diabetes
This study will examine the ability of olmesartan medoxomil to lower the blood pressure of patients with Type II diabetes and high blood pressure.
- Trial name
- NCT00403481
- Testing
- olmesartan medoxomil, Olmesartan medoxomil plus Hydrochlorothiazide
- Where
- 27 sites in United States
- Volunteers
- 192 people
- Sponsor
- Daiichi Sankyo
Neck Pain
The Effectiveness of Postural Stabilization Exercises in Patients With Chronic Neck Pain
This study aimed to evaluate the effect of postural stabilization exercises given in addition to cervical stabilization on craniovertebral angle, neck disability index, and quality of life in people with chronic neck pain.Sixty…
- Trial name
- NCT06578481
- Testing
- Exercises
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- European University of Lefke
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