Clinical trials: Physical activity
Multiple Sclerosis
Internet-Delivered Lifestyle Physical Activity Intervention for Cognitive Processing Speed in Multiple Sclerosis
We propose a highly-informed, well-designed randomized controlled trial (RCT) that is critical for providing Class I evidence regarding an Internet-delivered physical activity (PA) intervention as a behavioral approach for…
- Trial name
- BIPAMS-Cog (NCT04518657)
- Testing
- Behavioral Intervention for Physical Activity in MS (BIPAMS), Wellness for MS (WellMS)
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- University of Illinois Chicago
Physical Performance, Balance
Effects of Six-Week Accentuated Eccentric Load Training on Balance and Strength in Young Football Players
This study aims to investigate the effects of a structured training intervention on selected physical performance parameters in athletes.
- Conditions
- Physical Performance, Balance, Muscle Strength, Athletic Performance
- Trial name
- AEL-Balance (NCT07538557)
- Testing
- Accentuated Eccentric Training
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Gestational Age, Birth Weight
Resistance Exercise Training During Pregnancy: a Randomized Controlled Trial
The investigators investigated the effects of a supervised maternal exercise training program (performed during the 2nd and 3rd trimesters of pregnancy) on maternal-newborn unit health outcomes in a group of previously sedentary…
- Conditions
- Gestational Age, Birth Weight, Anaemia, Gestational Diabetes Mellitus
- Trial name
- NCT00813657
- Testing
- Exercise
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Urinary Incontinence
Physiotherapy Management in Women With Urinary Incontinence
Main objective: The primary aim of the study is to assess whether the author's exercise programme has an effect on reducing urinary incontinence and pelvic floor dysfunction after childbirth, considering vacuum extractor, forceps…
- Trial name
- NCT06581601
- Testing
- physiotherapy, exercises
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Obstructive Sleep Apnea (OSA)
Tongue Protrusion Force: A Pilot Study
From Weill Cornell Medical College Center for Sleep Medicine, the investigators will recruit patients (N = 25) with previously documented moderate to severe OSA.
- Trial name
- NCT02781701
- Testing
- Tongue Trainer
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Meningioma
S9005 Mifepristone in Meningioma
To compare daily oral mifepristone vs placebo with respect to time to treatment failure in patients with unresectable meningioma.
- Trial name
- NCT03015701
- Testing
- Mifepristone
- Volunteers
- 193 people
- Sponsor
- SWOG Cancer Research Network
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Clinical Decision-Making and Virtual Reality Exercise
Degenerative lumbar spine disease (DLSD) is common in elderly individuals and can result in pain, muscle weakness, and paresthesia.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Intervertebral Discs
- Trial name
- NCT05375201
- Testing
- VR skateboarding training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Physical Activity
Evaluating Incentive Designs to Increase Physical Activity Goal Adherence in a Wellness Program
This is a 4-week, five-arm, randomized, controlled trial to compare a standard wellness incentive program for physical activity to four other designs.
- Trial name
- NCT02629601
- Testing
- Active Rewards, Lottery 1, Lottery 2
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Select Advanced Solid Tumors
First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors
CDR404 is a highly potent and specific T-cell engaging bispecific and bivalent antibody designed for the treatment of cancers positive for the tumor-associated antigen melanoma-associated antigen 4 (MAGE-A4).
- Trial name
- NCT06402201
- Testing
- CDR404
- Where
- 20 sites in United States, Belgium and 4 more
- Volunteers
- 42 people
- Sponsor
- CDR-Life AG
Asthma
Effect Of Virtual Reality On Pulmonary Function And Anxiety Levels In Asthmatic Patients
The Purpose of the Study This study will be conducted to determine the effect of virtual reality on pulmonary function and anxiety levels in moderate to severe asthmatic patients.
- Trial name
- NCT07141212
- Testing
- Virtual reality glass, Buteyko Breathing
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- October 6 University
Idiopathic Parkinson's Disease, Parkinson Disease
Exploring Mechanisms for Neuropsychiatric Symptoms of Parkinson Disease Using Transcranial Direct Current Stimulation
This study evaluates the effect of transcranial direct current stimulation (tDCS) on non-motor symptoms of Parkinson's disease, including depression and cognitive symptoms.
- Conditions
- Idiopathic Parkinson's Disease, Parkinson Disease, Depression
- Trial name
- NCT03074812
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASH - Metabolic Dysfunction-Associated Steatohepatitis
Exercise for an Aging Liver (EXALIVER)
The goal of this clinical trial is to learn how physical exercise affects liver health in adults with metabolic dysfunction-associated steatotic liver disease (MASLD) or at-risk metabolic dysfunction-associated steatohepatitis…
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASH - Metabolic Dysfunction-Associated Steatohepatitis, Liver Fibrosis/NASH
- Trial name
- EXALIVER (NCT07467512)
- Testing
- Exercise, Usual Care
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Peripheral Arterial Disease
Effects of Individualized Exercise Training in Patients With Peripheral Arterial Disease
The study is designed to investigate individualized exercise training effects on arterial function, walking ability and quality of life in subjects with peripheral arterial disease post surgery.
- Trial name
- NCT00931112
- Testing
- individualized exercise training
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Taiwan University Hospital
Atrophy
Influence of β-hydroxy β-methyl Butyrate (HMB)Supplementation on Post-operative Muscle Mass and Function in Female Athletes
The proposed project will evaluate the musculoskeletal outcomes of quadriceps and hamstring muscle size and function following orthopedic knee surgery involving anterior cruciate ligament (ACL) repair or reconstruction.
- Trial name
- FAKS-HMB (NCT05869812)
- Testing
- CaHMB (Dietary supplement, not Drug), CaLa
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Low Back Pain
Aromatherapy Massage in Chronic Low Back Pain
The aim was to investigate the effectiveness of adding aromatherapy massage with a mixture of lavender and orange oil to conventional physical therapy in individuals with chronic nonspecific low back pain on pain, central…
- Trial name
- NCT07578181
- Testing
- Conventional Physiotherapy, Aromatherapy Massage + Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
HIV-1-infection
Study of GS-3242 in Participants With HIV-1; Substudy-05
This study is part of a master study. The goal of master protocol (GS-US-544-5905, NCT05585307) is to learn how novel antiretrovirals (medicines that stop the virus from multiplying) affect the human immunodeficiency virus-1…
- Trial name
- NCT07001319
- Testing
- GS-3242, BVY, Standard of Care
- Where
- 28 sites in United States, Mexico and 1 more
- Volunteers
- 27 people
- Sponsor
- Gilead Sciences
Pancreatic Cancer
Diet and Exercise After Pancreatic Cancer
Determine feasibility of a randomized controlled trial (RCT) in pancreatic (\& other foregut) cancer patients comparing the effects of diet alone vs. diet+exercise on functional and clinical outcomes.
- Trial name
- PACE (NCT03187028)
- Testing
- Diet Only, Diet + Exercise
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Alabama at Birmingham
Perinatal Anxiety
Antenatal Bre-Lax Education for Perinatal Anxiety Reduction and Self-efficacy Among Pregnant Women in Karachi's Urban Slums
Background Pregnant women in urban slums experience heightened stress and anxiety due to poor living conditions, limited healthcare access, and weak social support systems.
- Trial name
- NCT07787000
- Testing
- Arm 2: BreLax Intervention Group 1, Arm 3: Combined Intervention Group 3
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Bahria University
Parkinson Disease, Autonomic Dysfunction
Parkinson's Autonomic Responses to Treadmill Walking
This study will compare examine autonomic and cardiovascular responses to peak exercise testing in Parkinson's disease patients in varying stages of the disease, and healthy, age-matched participants.
- Trial name
- NCT03156400
- Testing
- Exercise Stress Test
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Core Stabilization, Respiration
Core Stabilization Training on Chest Expansion, Functional Capacity, Trunk Muscle Endurance in Hearing-Impaired Children
Children's motor skills and physical performance increase with age due to the development of neuromuscular and cardiorespiratory systems.
- Conditions
- Core Stabilization, Respiration, Functional Capacity, Endurance
- Trial name
- NCT06354400
- Testing
- Core stabilization training
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Bezmialem Vakif University
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