Clinical trials: Prednisolone, completed
Metastatic Castration-resistant Prostate Cancer, Metastatic Breast Cancer
A Study That Provides Long-term Safety Follow-up and Examines Long-term Exposure to Abiraterone Acetate
The purpose of this study is to collect follow-up safety data from participants in completed abiraterone acetate studies for a maximum duration of 9 years.
- Trial name
- NCT01517802
- Testing
- Abiraterone acetate, Prednisone
- Where
- 22 sites in United States, Australia and 5 more
- Volunteers
- 32 people
- Sponsor
- Janssen Research & Development, LLC
Prostate Cancer
Open Label Phase I/Randomised,Double Blind Phase II Study in mCRPC of AZD5363 In Combination With DP Chemotherapy
The aim of the ProCAID study is to determine if the addition of the AKT inhibitor AZD5363 to docetaxel and prednisolone (DP) prolongs progression free survival (PFS) in Metastatic castration resistant prostate cancer to a degree…
- Trial name
- ProCAID (NCT02121639)
- Testing
- AZD5363
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Community Acquired Respiratory Disease Syndrome
Extended Steroid in Use in Community Acquired Pneumonia (CAP)(e)
The goal of the study is to determine whether providing early treatment with a glucocorticoid drug, called methylprednisolone, will improve survival in critically ill patients with severe community-acquired pneumonia (CAP).
- Trial name
- ESCAPe (NCT01283009)
- Testing
- Inactive Substance, Methylprednisolone
- Where
- 30 sites in United States, Puerto Rico
- Volunteers
- 584 people
- Sponsor
- VA Office of Research and Development
Nasopharyngeal Carcinoma, Brain Necrosis
Effect of Edaravone on Radiation-induced Temporal Lobe Necrosis
It is hypothesized that excessive generation of free radicals involves in the pathogenesis of radiation-induced brain necrosis. This study therefore evaluated the effect of free radical scavenger, edaravone, on radiation-induced…
- Trial name
- NCT01865201
- Testing
- Edaravone, Common fundamental management
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hormone Resistant Prostate Cancer, Metastatic Prostate Cancer
Safety and Efficacy Study of of Docetaxel vs Docetaxel Estramustine in Hormone Refractory Prostatic Cancer
we propose to randomize patients with hormone resistant prostate cancer between docetaxel/estramustine/prednisone and docetaxel/prednisone in a phase II study. The principal endpoint will be the efficacy in term of PSA response.
- Trial name
- NCT00541281
- Testing
- docetaxel, estramustine, prednisone
- Where
- 19 sites in Belgium, Luxembourg
- Volunteers
- 150 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Follicular Lymphoma
Radiotherapy Versus Radiotherapy Plus Chemotherapy in Early Stage Follicular Lymphoma
Patients with stage I and II low grade follicular lymphoma are randomised between standard therapy (involved field radiotherapy) and investigational therapy (involved field radiotherapy and chemotherapy plus rituximab).
- Trial name
- NCT00115700
- Testing
- Cyclophosphamide, Radiotherapy, Vincristine
- Where
- 21 sites in Australia, Canada and 1 more
- Volunteers
- 150 people
- Sponsor
- Trans Tasman Radiation Oncology Group
Covid19
Short Term Low Dose Corticosteroids for Management of Post covid19 Pulmonary Fibrosis
A randomized controlled trial to study the efficacy of low dose steroid for 14 days in the treatment of post-covid-19 lung infiltrates
- Trial name
- NCT04551781
- Testing
- 20 Mg Prednisone for 14 days, control
- Where
- Egypt
- Volunteers
- 450 people
- Sponsor
- South Valley University
Epidermolysis Bullosa
MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs
This is a single-institution, phase II study to determine the event-free survival at 1 year post allogeneic transplant and serial mesenchymal stem cell (MSC) infusions from a related donor (HLA identical, mismatched or…
- Trial name
- NCT02582775
- Testing
- Thymoglobulin, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Metastatic ER+ Her2- Breast Cancer, Postmenopausal
A Study of Abiraterone Acetate Plus Prednisone With or Without Exemestane in Postmenopausal Women With Estrogen Receptor-Positive (ER+) Metastatic Breast Cancer Progressing After Letrozole or Anastrozole Therapy
The purpose of this study is to assess the safety and efficacy of oral abiraterone acetate plus oral prednisone and oral abiraterone acetate plus oral prednisone plus oral exemestane, each compared with oral exemestane alone, in…
- Trial name
- NCT01381874
- Testing
- Exemestane, Abiraterone acetate + Prednisone/ Prednisolone + Exemestane, Abiraterone acetate + Prednisone or Prednisolone
- Where
- 81 sites in United States, Belgium and 10 more
- Volunteers
- 297 people
- Sponsor
- Janssen Research & Development, LLC
Post-operative Edema, Steroid Use
Prospective Evaluation of Perioperative Steroid Dosing on Postsurgical Edema in Orthognathic Surgery
The current standard of care at the Oral and Maxillofacial Department at the CDHA is the use of one gram of methylprednisolone administered intravenously prior to orthognathic surgery. This is largely based on the work of Habal.
- Trial name
- NCT03190642
- Testing
- Methylprednisolone
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Jean Charles Doucet
Idiopathic Thrombocytopenic Purpura
The Effect of Eltrombopag on the Expression of Platelet Collagen Receptor GPVI in Pediatric ITP.
Using eltronmobag as an alternative pathway, which depend on stimulation of thrombocyte synthesis, in chronic and persistent immune thrombocytopenia may be more promising treatment than the classic type, not only by increasing…
- Trial name
- NCT03412188
- Testing
- Eltrombopag, conventional
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Nayera Hazaa Elsherif
Polymyalgia Rheumatica
Timed Release Tablet Prednisone in Polymyalgia Rheumatica
Polymyalgia Rheumatica (PMR) is a disease that usually affects older people. Patients complain of stiffness and pain around the shoulders and hips. The stiffness is more severe in the morning.
- Trial name
- NCT00836810
- Testing
- Timed Release Tablet Prednisone, Prednisolone
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
IgA Nephropathy
Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy (IgAN)
A multi-center, randomized, controlled clinical trial to evaluate the short-term and long-term efficacy and safety of mycophenolate mofetil (MMF) in reducing proteinuria and preserving renal function in patients with IgAN who…
- Trial name
- NCT00657059
- Testing
- irbesartan, methylprednisolone (MP) or prednisone (pred), mycophenolate mofetil (MMF)
- Where
- China
- Volunteers
- 151 people
- Sponsor
- Sun Yat-sen University
Lupus Nephritis
Pre-emptive Treatments in Lupus Nephritis Patients With Serological Reactivation
The optimal management of asymptomatic serological reactivation (ASR) in lupus nephritis (LN) patients remained undefined. This project aims to investigate the impact of pre-emptive treatment on disease relapse in LN patients who…
- Trial name
- NCT04870359
- Testing
- Pre-emptive increase of immunosuppressive treatments, Prednisolone and/or AZA/MMF
- Where
- 2 sites in Hong Kong
- Volunteers
- 49 people
- Sponsor
- The University of Hong Kong
Carpal Tunnel Syndrome
Local Steroid Injection vs Placebo in Carpal Tunnel Syndrome
Between 2008 and 2012 the investigators performed a single-center randomized double-blind placebo-controlled trial to assess the efficacy of local injection of two different doses of methylprednisolone (80 mg and 40 mg) in…
- Trial name
- NCT02652390
- Testing
- Methylprednisolone 80 mg, Methylprednisolone 40 mg, Saline
- Volunteers
- 111 people
- Sponsor
- Region Skane
Graft Vs Host Disease
Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)
To establish the safety and efficacy of two dose levels of ex-vivo cultured adult human mesenchymal stem cells (hMSCs) (Prochymal®) in participants experiencing acute GVHD, Grades II-IV, post hematopoietic stem cells (HSC)…
- Trial name
- NCT00136903
- Testing
- Prochymal® - 2 Million cells/kg, Prochymal®- 8 Million cells/kg, Methylprednisolone
- Where
- 9 sites in United States
- Volunteers
- 32 people
- Sponsor
- Mesoblast, Inc.
Peritoneal Neoplasms, Intestinal Obstruction
Octreotide Compared to Placebo in Patients With Inoperable Bowel Obstruction Due to Peritoneal Carcinomatosis
To evaluate in combination with corticosteroid and local standard medical care the efficacy and safety of long-acting octreotide compared to placebo for the treatment of symptoms of inoperable bowel obstruction in patients with…
- Conditions
- Peritoneal Neoplasms, Intestinal Obstruction, Carcinomatosis
- Trial name
- NCT00332696
- Testing
- Octreotide LAR, Octreotide (Immediate release), methylprednisolone
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Novartis Pharmaceuticals
Poisoning by Paraquat With Undetermined Intent
Role of CVVH in Patients With Acute Paraquat Poisoning
Paraquat poisoning is characterized by multiple organ failure and pulmonary fibrosis with respiratory failure. Accumulating evidence suggested that continuous venovenous hemofiltration (CVVH) had a beneficial role in the…
- Trial name
- PQ (NCT01709604)
- Testing
- CVVH, Standardized therapy regimens
- Where
- 2 sites in China
- Volunteers
- 110 people
- Sponsor
- Ai Peng
Systemic Sclerosis
Prednisolone in Early Diffuse Systemic Sclerosis
This is a randomised placebo-controlled study of moderate dose prednisolone for 6 months in patients with early diffuse cutaneous systemic sclerosis (dcSSc).
- Trial name
- PRedSS (NCT03708718)
- Testing
- Prednisolone 5 mg
- Where
- 14 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- Prof. Ariane herrick
Ganglion Cyst
Comparison of Thread Technique Versus Aspiration Plus Steroid Injection for Wrist Ganglion Recurrence
This study is a randomized controlled trial comparing two treatment methods for wrist ganglion cysts to evaluate which method has a lower recurrence rate.
- Trial name
- NCT06790615
- Testing
- methyl prednisolone acetate, Silk suture
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Benazir Bhutto Hospital, Rawalpindi
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