Clinical trials: Prednisolone, completed
Diabetes Mellitus, Type 1, Adrenal Insufficiency
Hypoglycaemia (Low Blood Sugar) in Adults With Diabetes and Adrenal Failure
The purpose of this study is to measure how often low blood sugars occur in people who live with both adrenal insufficiency (AI) and diabetes and need to take insulin.
- Conditions
- Diabetes Mellitus, Type 1, Adrenal Insufficiency, Diabetes Mellitus Type 2 - Insulin-Treated
- Trial name
- HYPO-DIAD (NCT05806190)
- Testing
- Continuous Glucose Monitoring
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Imperial College Healthcare NHS Trust
Abdominal Aortic Aneurysms
Preoperative Methylprednisolone in Endovascular Aortic Repair
The purpose of this study is to attenuate the systemic inflammatory response after Endovascular repair of abdominal aortic aneurysms, by administration of a single preoperative dosage of Methylprednisolone.
- Trial name
- POMEVAR (NCT00989729)
- Testing
- Methylprednisolone, Physiological Saline
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Louise de la Motte
Kidney Transplantation
A Study to Compare the Efficacy and Safety of FK506MR vs Prograf® in Patients Undergoing Kidney Transplantation
The patients about to undergo kidney transplantation will be randomized to one of the following two group: Group FK506MR: FK506MR/MMF/steroid; Group Prograf® : Prograf® /MMF/steroid. The treatment period is 3 months( 12 weeks)
- Trial name
- NCT00481819
- Testing
- FK506MR, Prograf, Mycophenolate Mofetil
- Where
- 9 sites in China
- Volunteers
- 240 people
- Sponsor
- Astellas Pharma Inc
Orthostatic Hypotension, Hemodynamic Instability
Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal Surgery
The purpose of this study is to evaluate the effect of low dose versus high dose steroids vital signs of patients currently on steroids or recently treated with steroids undergoing major colorectal surgery.
- Conditions
- Orthostatic Hypotension, Hemodynamic Instability, Fever, Hypothermia
- Trial name
- NCT01559675
- Testing
- Hydrocortisone High Dose, Hydrocortisone Low Dose
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Cedars-Sinai Medical Center
Graft Versus Host Disease
Photopheresis for the Treatment of Acute Graft Versus Host Disease
The goal of this clinical research study is to find out whether adding extracorporeal photopheresis (ECP) to standard therapy for acute GVHD with corticosteroids improves response to treatment, length of treatment, and survival.
- Trial name
- NCT00609609
- Testing
- Photopheresis, Methylprednisolone
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- M.D. Anderson Cancer Center
Polymyalgia Rheumatica
Abatacept in earLy Onset Polymyalgia Rheumatica: Study ALORS
Polymyalgia rheumatic (PMR) is a frequent inflammatory disease. It affects the elderly, with peak incidences at the age of 70 to 80 years; an age >50 years or older, is considered a criterion for the diagnosis.
- Trial name
- ALORS (NCT03632187)
- Testing
- Abatacept
- Where
- 5 sites in France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Brest
Asthma
Prednisolone Pharmacokinetics in Severe Asthma
The purpose of the study is to evaluate whether severe asthmatic subjects have abnormal prednisolone absorption, and how this might affect the anti-inflammatory effects of prednisolone. The aims of the study are 1.
- Trial name
- NCT00662298
- Testing
- prednisolone
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Imperial College London
Acute Urinary Tract Infection, Urinary Tract Infection
Corticosteroids for Children With Febrile Urinary Tract Infections
In this study the investigators will determine whether corticosteroids given at the time of urinary tract infection help prevent permanent damage to the kidneys.
- Trial name
- STARRS (NCT01391793)
- Testing
- Dexamethasone
- Where
- 6 sites in United States
- Volunteers
- 546 people
- Sponsor
- Nader Shaikh
CLASSICAL HODGKIN LYMPHOMA
Brentuximab Vedotin in Pre-transplant Induction and Consolidation for Relapsed or Refractory Hodgkin Lymphoma
Phase I trial aimed to determine the Maximum Tolerable Dose of the BV in combination with ESHAP in relapsed/resistant Hodgkin Lymphona patients and to evaluate response to treatment with BV-ESHAP as salvage regimen prior to…
- Trial name
- NCT02243436
- Testing
- Brentuximab Vedotin, Etoposide, Soludomerin
- Where
- 14 sites in Spain
- Volunteers
- 67 people
- Sponsor
- Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
HIV, Burkitt's Lymphoma
Short Term Intensified Chemo-immunotherapy in HIV-positive Patients With Burkitt Lymphoma
This is a multicenter,open-label trial to evaluate activity and safety of the investigational intensive in HIV+ patients with Burkitt's lymphoma.
- Trial name
- CARMEN (NCT01516593)
- Testing
- Induction Phase, Consolidation Phase (on day +50), Intensification phase
- Where
- 8 sites in Italy
- Volunteers
- 19 people
- Sponsor
- Andres J. M. Ferreri
Liver Diseases, Hepatocellular Cancer
A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation
Living donor liver transplantation (LDLT), involves complex systems and processes of care that are particularly vulnerable to medical errors and preventable complications.
- Conditions
- Liver Diseases, Hepatocellular Cancer, Endstage Liver Disease, Liver Cirrhosis
- Trial name
- NCT02073435
- Testing
- Donor pain management
- Where
- 4 sites in United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Graft Versus Host Disease
Beclomethasone Plus Prednisone in Treating Patients With Graft-Versus-Host Disease
RATIONALE: Beclomethasone combined with prednisone may be an effective treatment for graft-versus-host disease caused by stem cell transplantation.
- Trial name
- NCT00043147
- Testing
- beclomethasone dipropionate, methylprednisolone, prednisone
- Where
- 2 sites in United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Spinal Cord Injuries
Impact of Intermittent Hypoxia and Prednisolone on Motor Performance in Persons With SCI
The objective of this study is to examine the effects of mild acute intermittent hypoxia (AIH) in combination with an anti-inflammatory drug (i.e. prednisolone) on motor performance in persons with spinal cord injury (SCI).
- Trial name
- NCT03752749
- Testing
- Prednisolone + Acute Intermittent Hypoxia
- Volunteers
- 14 people
- Sponsor
- Shirley Ryan AbilityLab
Prostate Cancer
Extension of SoluMatrix TM Abiraterone Acetate in Patients Who Completed Study Number CHL-AA-201
An Open-label extension (OLE), expanded access study, to assess long-term safety of SoluMatrix™ Abiraterone Acetate 500mg (4 x 125 mg qd) with Methylprednisolone (4mg bid) in patients who completed study number CHL-AA-201.
- Trial name
- NCT02887976
- Testing
- SoluMatrix™ Abiraterone Acetate, Methylprednisolone
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- GU Research Network, LLC
Chronic Obstructive Pulmonary Disease
Budesonide / Formoterol in Treatment of Exacerbations of COPD
The purpose of this study is to determine whether the budesonide+formoterol combination is effective in the treatment of exacerbations of COPD with a main emphasis on investigating the effects on inflammation and a secondary…
- Trial name
- NCT00239278
- Testing
- budesonide/formoterol, 2x 200/6 microgram. 4 times daily
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- AstraZeneca
Gastrointestinal Stromal Tumor(GIST)
Management of Imatinib-associated Severe Skin Rash in Patients With Gastrointestinal Stromal Tumor
To achieve optimal clinical outcomes with imatinib in GIST patients, it is crucial to maintain standard imatinib dose. Skin rash is a relatively common and sometimes severe adverse event of imatinib in GIST patients and may…
- Trial name
- NCT03440515
- Testing
- Prednisone
- Volunteers
- 29 people
- Sponsor
- Asan Medical Center
Epiphora Due to Insufficient Drainage
OCT Guided Punctal Stenosis Management
This is a clinical trial study that was conducted on patients with punctal stenosis.We studied the diameter of stenosed puncta before and after treatment with preserved free steroid eye drops using AS-OCT.
- Trial name
- NCT04318652
- Testing
- Methylprednisolone eyedrops
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Post-operative Nausea, Post-operative Vomiting
Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery
The purpose of this study is to determine whether a multi-modal anesthesia and pain control protocol reduces post-operative and post-discharge nausea and vomiting (PONV and PDNV) in patients undergoing upper jaw corrective…
- Conditions
- Post-operative Nausea, Post-operative Vomiting, Nausea Persistent
- Trial name
- NCT01592708
- Testing
- Antiemetic anesthesia protocol
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of North Carolina, Chapel Hill
Heart Arrest
Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest
A randomized controlled trial did not show benefit of vasopressin versus epinephrine in inhospital cardiac arrest. Preceding laboratory data suggest that combined vasopressin and epinephrine ensure long-term survival and…
- Trial name
- NCT00411879
- Testing
- Vasopressin, Epinephrine, and Steroids
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Athens
Prostate Cancer
Cabazitaxel at 20 mg/m² Compared to 25 mg/m² With Prednisone for the Treatment of Metastatic Castration Resistant Prostate Cancer
Primary Objective: To demonstrate the non inferiority in term of overall survival (OS) of Cabazitaxel 20 mg/m² (Arm A) versus Cabazitaxel 25 mg/m² (Arm B) in combination with prednisone in participants with metastatic castration…
- Trial name
- PROSELICA (NCT01308580)
- Testing
- Cabazitaxel (XRP6258), Prednisone (or Prednisolone)
- Where
- 172 sites in United States, Argentina and 20 more
- Volunteers
- 1,200 people
- Sponsor
- Sanofi
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