Clinical trials: Propranolol, completed
Dental Anxiety
The Effects of Propranolol on Fear of Tooth or Molar Extraction
Randomized, placebo-controlled, double-blind, parallel group clinical trial evaluating the anxiolytic effects of propranolol on fear of wisdom tooth removal.
- Trial name
- NCT02268357
- Testing
- Propranolol
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Arrhythmia, Cardiovascular Diseases
Beta-Blocker Heart Attack Trial (BHAT)
To determine whether the regular administration of the beta-blocker drug propranolol to people who had had at least one documented myocardial infarction would result in a significant reduction of mortality from all causes over…
- Conditions
- Arrhythmia, Cardiovascular Diseases, Coronary Disease, Death, Sudden, Cardiac
- Trial name
- NCT00000492
- Testing
- propranolol
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cerebral Cavernous Malformation
Treat_CCM: Propranolol in Familial Cerebral Cavernous Malformation
Cerebral Cavernous Malformation (CCM) is a cerebrovascular disease which can be either congenital in origin or sporadic and is characterized by the presence of isolated or multiple CCM lesions, causing recurrent headache…
- Trial name
- Treat_CCM (NCT03589014)
- Testing
- Propranolol
- Where
- 6 sites in Italy
- Volunteers
- 71 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Cirrhosis
Liver Transplantation Versus Alternative Therapies for Patients With Pugh B Alcoholic Cirrhosis
Liver transplantation has been universally recognized to improve survival of patients suffering from end-stage (Pugh C) alcoholic cirrhosis.
- Trial name
- TRANSCIAL (NCT00701792)
- Testing
- liver transplantation, standard care for liver disease
- Where
- 13 sites in France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Cocaine Dependence
Beta-blockade Effects on Memory for Cocaine Craving
The purpose of this study is to examine the effects of propranolol versus placebo on responses to cocaine cues in cocaine dependent individuals.
- Trial name
- NCT00830362
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical University of South Carolina
Pulmonary Disease, Chronic Obstructive
Optimising the Propranolol Block Model
Optimising the propranolol block model
- Trial name
- NCT00549120
- Testing
- Propranolol, Salbutamol, Ipratropium
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Migraine Without Aura
ACT Therapy for HF Migraine
The aim is to compare the effectiveness of a behavioral treatment, the Acceptance and Commitment Therapy, provided as an add-on to the prophylactic treatment (treatment as usual-TaU) against TaU only on the reduction of monthly…
- Trial name
- ACTMigraine (NCT03461874)
- Testing
- Education of patients, ACT, Pharmacological prophylaxis
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Hematopoietic Stem Cell Transplantation
Pilot Study Using Propranolol To Promote Prenylation Of Gtpase Rap1b In Hematopoietic Stem Cell Transplant Recipients
This is a an ancillary study designed to explore whether an additional cell signaling pathway (prenylation of Rap1) that was recently identified as being under beta-adrenergic control may be affected by beta-blocker use.
- Trial name
- NCT02535182
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical College of Wisconsin
Atrial Fibrillation, Arrhythmia
Catheter Ablation vs Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial
The (Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial) CABANA Trial has the overall goal of establishing the appropriate roles for medical and ablative intervention for atrial fibrillation (AF).
- Trial name
- CABANA (NCT00911508)
- Testing
- Left atrial ablation, Rate or Rhythm Control Therapy
- Where
- 118 sites in United States, Australia and 8 more
- Volunteers
- 2,204 people
- Sponsor
- Mayo Clinic
Atrial Fibrillation, Arrhythmia
Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial
The CABANA pilot study is designed to test the hypothesis that the treatment strategy of percutaneous left atrial catheter ablation for the purpose of the elimination of atrial fibrillation (AF) is superior to current…
- Trial name
- CABANA (NCT00578617)
- Testing
- Rate Control, Ablation Therapy, Rhythm Control
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Vestibular Migraine
Comparison of Propranolol and Venlafaxine in Treatment of Vestibular Migraine
The presented study aims to compare effectivity of propranolol with effectivity of venlafaxine in escalating dose in subjects with vestibular migraine (VM) over a period of 12 weeks.
- Trial name
- NCT02350985
- Testing
- Propranolol, Venlafaxine
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Haseki Training and Research Hospital
To Determine Bioequivalence Under Fed Conditions
Bioavailability Study of Propranolol Under Fed Conditions
To compare the single-dose bioavailability of Propranolol 160 Mg ER Capsules with Inderal-La
- Trial name
- NCT00652600
- Testing
- Propranolol, Inderal-LA
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Insulin Sensitivity, Obesity
The Effect of Brown Adipose Tissue Activation on Insulin Sensitivity in Humans
Recent findings document the presence of active brown adipose tissue (BAT) in humans. Cold exposure via adrenergic stimulation activates BAT, which combusts significant amounts of blood glucose and free fatty acid (FFA) to…
- Trial name
- NCT01791114
- Testing
- Cold exposure, Cold exposure plus propranolol, Thermoneutral Conditions
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Healthy Subjects
Influence of Propranolol on Conditioned Pain Modulation
An extensive amount of studies indicate that conditioned pain modulation (CPM) test paradigms can be of use to evaluate the efficacy of the endogenous pain inhibition pathway in healthy controls and pain patients.
- Trial name
- NCT02808611
- Testing
- propranolol
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Kristian Kjær Petersen
Stress, Psychological, Inflammation
Does Propranolol Attenuate Inflammatory Responses to a Psychological Stressor?
This randomized, double-blind, placebo-controlled study of propranolol will shed important light on how sympathetic nervous system (SNS) activation influences psychological and inflammatory responses to acute stress.
- Conditions
- Stress, Psychological, Inflammation, Cortisol, Sympathetic Nervous System
- Trial name
- NCT02972554
- Testing
- Propanolol hydrochloride
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
A Study of Ponesimod in Healthy Adult Participants Receiving Propranolol at Steady State
The primary purpose of this study is to evaluate the effect of the up-titration regimen of ponesimod on heart rate (HR) and other electrocardiogram (ECG) parameters when administrated to healthy adult participants receiving…
- Trial name
- NCT03882255
- Testing
- Ponesimod dose range (2 - 20 mg), Propranolol 80 mg
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Stroke
Beta Blockers In Acute Ischemic Stroke
The objective of this trial is to assess the safety and efficacy of neuro- and cardioprotective effects of propranolol in acute ischemic stroke.
- Trial name
- BIAS (NCT01061190)
- Testing
- Propranolol
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Wilhelm Haverkamp
Type 2 Diabetes Mellitus
A Single-Dose Crossover Study of MK0893 in Patients With Type 2 Diabetes (0893-019 AM4)(COMPLETED)
This study will assess the effect of combined treatment with MK0893 plus propranolol versus placebo plus propranolol on hypoglycemia.
- Trial name
- NCT00902161
- Testing
- MK0893, Propranolol Hydrochloride (HCL)
- Volunteers
- 22 people
- Sponsor
- Merck Sharp & Dohme LLC
Antisepsis
Pre-surgical Antisepsis of Hands After Washing With Triclosan 0.5% Compared to Propan-1-ol 60%
The present study evaluates the effects of bactericidal load reduction after surgical hand scrub antisepsis using the reference antiseptic product propanol- 1 60% as control versus a surgical hand scrub antisepsis with triclosan…
- Trial name
- NCT04538365
- Testing
- Triclosan 0.5 % Topical Solution, propanolol
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centro Ortopedico y Quirurgico del Pie
Vestibular Migraine, Vestibular Disorder
Vestibular Rehabilitation in Patients With Vestibular Migraine
Abstract: Introduction: Vestibular migraine(VM) is a disease that manifests with episodic vertigo attacks in patients with or without migraine type headaches, when present accompanying the headaches.
- Conditions
- Vestibular Migraine, Vestibular Disorder, Migraine Variant
- Trial name
- NCT03417596
- Testing
- Control, Vestibular Rehabilitation
- Volunteers
- 77 people
- Sponsor
- Ege University