Clinical trials: Radiation, completed
Inflammatory Breast Cancer
Interest of Maintenance Chemotherapy After Induction Treatment for Inflammatory Breast Cancer
To evaluate the benefit of adding docetaxel-5 fluorouracile (D-5FU) regimen after pre-operative epirubicin-cyclophosphamide (EC) and loco-regional treatment in inflammatory breast cancer (IBC).
- Trial name
- PEGASE07 (NCT02324088)
- Testing
- Docetaxel, Cyclophosphamide, Epirubicin
- Volunteers
- 174 people
- Sponsor
- UNICANCER
Lung Cancer Non-Small Cell Cancer (NSCLC)
Real-World Immuno-Radiotherapy for Advanced NSCLC
The optimal combination strategy for radiotherapy combined with immunotherapy (iRT) in advanced non-small-cell lung cancer (NSCLC) remains unclear, and there is a lack of real-world data to validate its efficacy.
- Trial name
- OCEANUS (NCT06747026)
- Testing
- initial Sequential iRT, initial Concurrent iRT, RT with maintenance of ICI
- Where
- Hong Kong
- Volunteers
- 338 people
- Sponsor
- Fengming Kong
Prostate Cancer
Radiation Therapy With or Without Bicalutamide and Goserelin in Treating Patients With Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation therapy in different ways may cause less damage to normal tissue and may improve quality of life and help patients live more…
- Trial name
- NCT00067015
- Testing
- bicalutamide, goserelin acetate, assessment of therapy complications
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Acromegaly
Acromegaly: Balance, Falls and Fracture Risk
The goal of this observational, cross-sectional study is to study bone quality, joint quality and fall risk in acromegalic patients, compared with healthy controls.
- Trial name
- NCT05752825
- Testing
- HR-pQCT, DXA scan, Bone microindentation
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Christian Alexander H Rosendal
Fanconi Anemia
TBI Dose De-escalation for Fanconi Anemia
This is a single arm, total body irradiation (TBI) trial. All patients will be prescribed TBI 300 cGy with the goal of evaluating secondary endpoints.
- Trial name
- NCT00352976
- Testing
- Cyclophosphamide, Fludarabine, Total Body Irradiation
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Prostate Cancer
Intensity Modulated Radiation Therapy (IMRT) Radiotherapy for Treating Prostate Pelvic Nodes
The purpose of this study is to examine the clinical feasibility and efficacy of uing IMRT to escalate the biologically effective dose to the pelvic lymph nodes in a short course of radiation therapy.
- Trial name
- NCT00214136
- Testing
- radiotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Wisconsin, Madison
Crohn Disease
Non-invasive Approaches to Identify the Cause of Fatigue in Inflammatory Bowel Disease Patients.
Crohn's disease (CD) presents with severe symptoms, but fatigue is a very predominant symptom that negatively impacts upon quality of life.
- Trial name
- IBD Fatigue (NCT03670693)
- Testing
- Muscle strength and fatigue assessment, Dual-energy X-ray absorptiometry (DEXA scan), Supine cardiorespiratory fitness assessment
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Urothelial Carcinoma, Bladder Cancer
Phase I Study With Sorafenib in Addition to Vinflunine in Metastatic Transitional Cell Carcinoma of the Urothelial Tract
This study aims to analyse the tolerability (side effects and safety) with standard treatment (Javlor®) with the addition of a second anti-tumour drug: sorafenib (Nexavar®).
- Conditions
- Urothelial Carcinoma, Bladder Cancer, Renal Pelvis Cancer, Ureter Cancer
- Trial name
- VINSOR (NCT01844947)
- Testing
- Vinflunine, Sorafenib
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 22 people
- Sponsor
- Dr Anders Ullén
Breast Neoplasms
Ultrasound Targeting for the Lumpectomy Cavity
Accurate targeting of treatment sites should increase local control by radiation therapy for breast-cancer lumpectomy patients. Currently, ultrasound localization is used for prostate cancer patients to locate the prostate before…
- Trial name
- NCT00583843
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Iowa
Total Knee Replacement
Physica KR Fluoroscopy Study
The aim of this study is to assess the in vivo kinematics and range of motion of a single-surgeon clinical series of TKA performed with a fixed-bearing cruciate retaining total knee arthroplasty that has a roll-back mechanism and…
- Trial name
- NCT02655809
- Testing
- Fluoroscopic examination
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Limacorporate S.p.a
Cholangiocarcinoma Cancer, Gallbladder Cancer
A Feasibility Phase II Study in the Treatment of Resected Cholangiocarcinoma, Gallbladder, Pancreatic and Ampullary Cancers
To assess the feasibility of administering induction chemotherapy with gemcitabine and docetaxel followed by concurrent radiation and continuous infusion 5FU and consolidation gemcitabine/docetaxel chemotherapy.
- Conditions
- Cholangiocarcinoma Cancer, Gallbladder Cancer, Pancreatic Cancer, Ampullary Cancer
- Trial name
- NCT00660699
- Testing
- Gemcitabine, Docetaxel, Radiation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Cervical Cancer
Randomized Study of Z-100 Plus Radiation Therapy to Treat Cervical Cancer
This study is a phase III, multicenter, double-blind, placebo-controlled, parallel group comparative study to evaluate the efficacy and safety of Z-100 with primary uterine cervical cancer on radiotherapy.
- Trial name
- NCT02247232
- Testing
- Z-100
- Where
- 7 sites in Japan, Malaysia and 5 more
- Volunteers
- 793 people
- Sponsor
- Zeria Pharmaceutical
Distal Radius Fracture, Loss of Anatomical Alignment After Fracture Reduction
Prospective Evaluation of Cast Bivalving for Pediatric Distal Radius Fractures
Pediatric patients with distal radius fractures are most commonly treated non-operatively with fracture reduction and cast immobilization.
- Trial name
- NCT05716438
- Testing
- Forearm anteroposterior and lateral plain radiograph
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Pancreatic Cancer Stage IVA
Study for Inoperable Non-Metastatic Pancreatic CA (Stage IVA) With Neoadjuvant GTX, and Radiation With Gemzar
The purpose of this study is to determine whether an experimental drug combination consisting of Gemzar®, Taxotere®, and Xeloda®, (called GTX) when followed by radiation therapy plus low-dose Gemzar, is safe and effective in…
- Trial name
- NCT00869258
- Testing
- Gemcitabine, docetaxel, and capecitabine, Radiation therapy with gemzar
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Columbia University
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant
This phase I/II trial studies whether stopping cyclosporine before mycophenolate mofetil is better at reducing the risk of life-threatening graft-versus-host disease (GVHD) than the previous approach where mycophenolate mofetil…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
- Trial name
- NCT00078858
- Testing
- fludarabine phosphate, total-body irradiation, nonmyeloablative allogeneic hematopoietic stem cell transplantation
- Where
- 10 sites in United States, Germany and 1 more
- Volunteers
- 37 people
- Sponsor
- Fred Hutchinson Cancer Center
Community Acquired Pneumonia
A Global Active Surveillance for Community Acquired Pneumonia
This study is an observational surveillance study to identify adults 50 years and older who present to a study healthcare facility with signs and symptoms of Community-Acquired Pneumonia.
- Trial name
- NCT00929721
- Testing
- Blood draw, Chest X-ray, urine specimen
- Where
- Poland
- Volunteers
- 5,172 people
- Sponsor
- Pfizer
Corneal Ectasia
Three Different Cross-linking Protocols for Treatment of Pediatric Keratoconus
comparison between standard cross-linking protocol and accelerated and transepithelial cross-linking
- Trial name
- NCT05691335
- Testing
- Standard CXL, Accelerated CXL, Transepithelial CXL
- Where
- Egypt
- Volunteers
- 97 people
- Sponsor
- Sohag University
Emphysema
Lung Volume Reduction for Severe Emphysema by Stereotactic Ablative Radiation Therapy
Since medical therapies offer only modest palliation and minimal hopes for improved survival to COPD patients, surgical therapies have been designed that may provide greater benefits in selected patients.
- Trial name
- NCT03673176
- Testing
- Stereotactic Ablative Radiotherapy (SABR)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stanford University
Head and Neck Cancer, Lung Cancer
Paclitaxel and Cisplatin Plus Radiation Therapy Followed by Filgrastim in Treating Patients With Recurrent Head and Neck Cancer or Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00021333
- Testing
- filgrastim, cisplatin, paclitaxel
- Where
- 18 sites in United States
- Volunteers
- 29 people
- Sponsor
- Fox Chase Cancer Center
Immediate Implant Soft Tissue Healing
ASSESSMENT OF SOFT TISSUE HEALING OVER IMMEDIATELY PLACED IMPLANT SEALED WITH PLATELETS RICH FIBRIN (PRF) VERSUS DIODE LASER
Aim of the current study was to assess the efficacy of PRF in comparison to diode laser to promote tissue healing and soft tissue quality after placement of immediate implants.
- Trial name
- NCT05517733
- Testing
- Platelet Rich Fibrin, Diode laser
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Nourhan M.Aly
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