Clinical trials: Radiation, completed
Nasopharyngeal Cancer
Assessment of Treatment Response of Nasopharyngeal Cancer Using Simultaneous 18F-FDG-PET and MRI
The overarching goal of this study is to develop PET/MR techniques for accurate assessment of treatment response during and immediately after chemoradiation therapy.
- Trial name
- NCT03656250
- Testing
- PET/CT scans
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- NYU Langone Health
Cervical Cancer
Bintrafusp Alfa Combination Therapy in Participants With Cervical Cancer (INTR@PID 046)
This study was to evaluate the safety and tolerability of bintrafusp alfa in combination with other anti-cancer therapies in participants with locally advanced or advanced cervical cancer.
- Trial name
- NCT04551950
- Testing
- M7824, Carboplatin, Paclitaxel
- Where
- 13 sites in United States, Japan and 1 more
- Volunteers
- 25 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.
Head and Neck Cancer
A Trial of Concurrent Radiation Therapy, Cisplatin, and BMX-001 in Locally Advanced Head and Neck Cancer
This is a Phase 1 / Phase 2 study of newly diagnosed patients with biopsy-proven head and neck cancer (squamous cell carcinoma) who are undergoing standard radiation therapy and treatment with cisplatin.
- Trial name
- BMX-HN (NCT02990468)
- Testing
- BMX-001, Radiation Therapy, Cisplatin
- Where
- 4 sites in United States
- Volunteers
- 29 people
- Sponsor
- BioMimetix JV, LLC
Acute Respiratory Failure
Human Algorithm Interactions for Acute Respiratory Failure Diagnosis
Artificial intelligence (AI) shows promising in identifying abnormalities in clinical images. However, systematically biased AI models, where a model makes inaccurate predictions for entire subpopulations, can lead to errors and…
- Trial name
- NCT06098950
- Testing
- Artificial Intelligence model predictions without explanation, Artificial intelligence model predictions with explanation, AI model biased against heart failure
- Where
- United States
- Volunteers
- 457 people
- Sponsor
- University of Michigan
Sacroiliitis
Significance and Outcome of Magnetic Resonance Enterography Revealing Sacroiliitis in Crohn's Disease: A Pilot Study
This study aims to further define and characterize imaging findings of possible sacroiliitis in Crohn's Disease patients by recalling subjects who had findings of possible sacroiliitis on prior MRE and assess the natural history…
- Trial name
- NCT05203926
- Testing
- MRI scan
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- NYU Langone Health
Sun Protection
Evaluation of Sunscreens Under Actual Use Conditions
Use of two high SPF sunscreens under actual use conditions.
- Trial name
- NCT02952235
- Testing
- SPF50+, SPF100+
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Sarcoma
Radiation Therapy With or Without SU5416 in Treating Patients With Soft Tissue Sarcoma
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as SU5416 may stop the growth of cancer by stopping blood flow to the tumor.
- Trial name
- NCT00023725
- Testing
- semaxanib, conventional surgery, radiation therapy
- Where
- 226 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
Oral Mucositis
Lactobacillus Rhamnosus GG Alleviates Oral Mucositis in Patients Undergoing Radiotherapy
Radiation therapy is a common treatment modality in the management of head and neck malignancies. However, head and neck tumors often have some adverse reactions when receiving radiation therapy, such as dry mouth, change of…
- Trial name
- NCT06390176
- Testing
- Lactobacillus rhamnosus GG, Radiotherapy
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Prostate Cancer, Sexual Dysfunction
Intensity-Modulated Radiation Therapy With or Without Decreased Radiation Dose to Erectile Tissue in Treating Patients With Stage II Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Intensity-modulated radiation therapy (radiation directed at the tumor more precisely than in standard radiation therapy) may reduce damage to healthy…
- Conditions
- Prostate Cancer, Sexual Dysfunction, Sexuality and Reproductive Issues
- Trial name
- NCT00084552
- Testing
- radiation therapy
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Fox Chase Cancer Center
Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) Patient Positioning in EOS System®
The EOS® imaging system, a new imaging modality which offers low dose, weight bearing and full body X-ray imaging, requires a new standing position where patients put their hands and forearms on the wall vertically for stability.
- Trial name
- NCT02269657
- Testing
- EOS® imaging system
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Children's Hospital of Philadelphia
Melanoma
Nivolumab Plus Radiotherapy in Advanced Melanoma
Combining nivolumab with conventional multisite high dose radiotherapy seems to be an interesting approach that could increase the antitumoral effect of nivolumab by increasing the diversity and quantity of tumoral antigen…
- Trial name
- NIRVANA (NCT02799901)
- Testing
- Nivolumab, hypofractionned radiotherapy
- Where
- 14 sites in France
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cancer
Preoperative Imaging in Retroperitoneal Sarcoma
This is a prospective observational study in which patients with untreated retroperitoneal sarcoma will have Magnetic Resonance Imaging (MRI) prior to surgery.
- Trial name
- PIRS (NCT01902667)
- Testing
- Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Meningioma, Hemangiopericytoma
Proton Radiation For Meningiomas and Hemangiopericytomas
This is a Feasibility/Phase II study for patients with a diagnosis of WHO Grade I - III Meningioma \& Hemangiopericytoma brain cancer to be given standard dose Proton radiotherapy.
- Trial name
- NCT01117844
- Testing
- Proton Radiation
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Head and Neck Neoplasms
A Study of Prexasertib (LY2606368) With Chemotherapy and Radiation in Participants With Head and Neck Cancer
The main purpose of this study is to investigate the safety of prexasertib in combination with other anti-cancer drugs (cisplatin or cetuximab) and radiation therapy in participants with locally advanced head and neck cancer.
- Trial name
- NCT02555644
- Testing
- Prexasertib, Cisplatin, Cetuximab
- Where
- 4 sites in United States, France
- Volunteers
- 70 people
- Sponsor
- Eli Lilly and Company
Head and Neck Cancer
Xerostomia in Head and Neck Cancer Patients Receiving Radiation as the Primary Treatment Versus Patients Who Will Not Have Such a Procedure
The purpose of this study is to compare the side effects of radiation treatment and surgery versus radiation alone, where no surgery is done to move the salivary gland and place it under the chin region where it can be shielded…
- Trial name
- NCT00168116
- Testing
- radiation treatment and surgery, radiation alone
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- AHS Cancer Control Alberta
Brain and Central Nervous System Tumors, Neuroblastoma
Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors
RATIONALE: Monoclonal antibodies can locate tumor cells and deliver tumor-killing substances, such as radioactive iodine, to them without harming normal cells.
- Trial name
- NCT00003484
- Testing
- carmustine, irinotecan hydrochloride, surgical procedure
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Darell D. Bigner, MD, PhD
Lung Cancer
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Stage I-IIIB Non-Small Cell Lung Cancer After Completion of Radiation Therapy Alone or Combined Radiation Therapy and Chemotherapy
RATIONALE: Radiation therapy uses high energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as carboplatin, paclitaxel, cisplatin, and etoposide, work in different ways to stop the growth of tumor cells, either by…
- Trial name
- NCT00738452
- Testing
- high performance liquid chromatography, pharmacological study, radionuclide imaging
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- City of Hope Medical Center
Stage I Kidney Wilms Tumor, Stage II Kidney Wilms Tumor
Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor
This phase III trial is studying vincristine, dactinomycin, and doxorubicin with or without radiation therapy or observation only to see how well they work in treating patients undergoing surgery for newly diagnosed stage I…
- Conditions
- Stage I Kidney Wilms Tumor, Stage II Kidney Wilms Tumor, Stage III Kidney Wilms Tumor
- Trial name
- NCT00352534
- Testing
- 3-Dimensional Conformal Radiation Therapy, Biospecimen Collection, Chest Radiography
- Where
- 240 sites in United States, Australia and 5 more
- Volunteers
- 808 people
- Sponsor
- Children's Oncology Group
Radiotherapy; Adverse Effect, Dermatitis or Eczema, Breast Neoplasms
Laser InGaAlP (660Nm) to Prevent Radiodermatitis in Breast Cancer Patients Submitted to Radiation Therapy
Breast neoplasm is the second most common type in the world. Radiation therapy is a key component in the treatment of breast cancer. Acute skin reaction is one of the most common side effects of radiation therapy.
- Trial name
- NCT02003599
- Testing
- Laser therapy
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Universidade do Vale do Sapucai
Healthy
CRF - Nociceptin Receptor Interactions
To determine if [C-11]NOP-1A receptor binding (VT) can be altered by an intravenous hydrocortisone (cortisol) challenge through CRF-NOP interactions
- Trial name
- NCT03302416
- Testing
- Hydrocortisone, [C-11]NOP-1A
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
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