Clinical trials: Radiation, completed
Small Cell Lung Cancer Extensive Stage, Thoracic Radiotherapy
Thoracic RadiothErapy With Atezolizumab in Small Cell lUng canceR Extensive Disease
This is a multicenter phase 2 clinical trial to investigate the treatment efficacy and feasibility of combining thoracic radiotherapy (TRT) with the IMpower133 regimen in the upfront treatment of ED SCLC patients.
- Trial name
- TREASURE (NCT04462276)
- Testing
- Atezolizumab, thoracic radiotherapy (TRT)
- Where
- 20 sites in Austria, Germany
- Volunteers
- 68 people
- Sponsor
- Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Locally Advanced Malignant Neoplasm, Inflammatory Breast Carcinoma
Olaparib and Radiotherapy in Inoperable Breast Cancer
The majority of breast cancer patients receive radiotherapy as part of their treatment. Radiotherapy improves both locoregional control and overall survival.
- Conditions
- Locally Advanced Malignant Neoplasm, Inflammatory Breast Carcinoma, Triple-Negative Invasive Breast Carcinoma
- Trial name
- NCT02227082
- Testing
- radiotherapy, olaparib
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- The Netherlands Cancer Institute
Ultrasound for Diagnosis of CVC Position in Children
Feasibility Study of CVC Diagnosis Via Ultrasound in Children
After the placement of a central venous catheter in children, a routine chest X-ray will be performed in order to examine the correct position of the catheter.
- Trial name
- CVC (NCT02178423)
- Testing
- Ultrasound for diagnosis of CVC position in children
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Vienna
Squamous Cell Carcinoma of the Oropharynx, HPV
Reduced-intensity Therapy for Oropharyngeal Cancer in Non-smoking HPV-16 Positive Patients
Taking into account the excellent prognosis of patients with HPV-positive oropharyngeal cancer with < 10 pack-year smoking, the investigators hypothesize that reducing the intensity of therapy for these patients will reduce…
- Trial name
- NCT01663259
- Testing
- Cetuximab, Radiotherapy
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Michigan Rogel Cancer Center
Colorectal Cancer
Study of TAS-102 Plus Radiation Therapy for the Treatment of the Liver in Patients With Hepatic Metastases From Colorectal Cancer
This research study is studying a drug in combination with radiation therapy as a possible treatment for hepatic metastases from colorectal cancer.
- Trial name
- NCT03223779
- Testing
- TAS-102, Photon SBRT
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Massachusetts General Hospital
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Acute
Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)
Bone marrow transplants are one treatment option for people with leukemia or lymphoma. Family members or unrelated donors with a similar type of bone marrow usually donate their bone marrow to the transplant patients.
- Conditions
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Acute, Burkitt Lymphoma, Lymphoma, B-Cell
- Trial name
- NCT00849147
- Testing
- Haploidentical Bone Marrow Transplantation, GVHD prophylaxis
- Where
- 17 sites in United States
- Volunteers
- 55 people
- Sponsor
- Medical College of Wisconsin
Clear Cell Renal Cell Carcinoma Metastatic
Pharmacokinetics, Biodistribution, Radiation Dose and Safety Study of 68Ga-NYM005 in Patients
68Ga-NYM005 is a CAIX-targeting small-molecular radiotracer for PET/CT imaging of clear cell renal cell carcinoma
- Trial name
- NCT06389682
- Testing
- 68Ga-NYM005 injection
- Where
- 2 sites in China
- Volunteers
- 19 people
- Sponsor
- Norroy Bioscience Co., LTD
Glioblastoma
Retrospective Evaluation of Melanocortin Receptor 4 Polymorphisms in Patients With GBM Treated With Radiochemotherapy
Glioblastoma (GBM) accounts for approximately 50% of all glioma and among these tumors, are the most malignant. The cells of origin of glioma are still undefined, but the most putative target cells include astrocytes, neural stem…
- Trial name
- GLIOMELA (NCT02458508)
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- University of Pisa
Head and Neck Squamous Cell Carcinoma, Malignant Head and Neck Tumors
A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy
To evaluate the efficacy and safety of lithium-containing mouthwash for prevention and treatment of oral mucositis and dysgeusia in patients undergoing radiotherapy for malignant head and neck tumors.
- Trial name
- NCT06251050
- Testing
- lithium-containing mouthwash （Phase I）, Plcacebo mouthwash （Phase II）, lithium-containing mouthwash（Phase II）
- Where
- China
- Volunteers
- 175 people
- Sponsor
- West China Hospital
Liver Cancer
Interventional X-ray and Scintigraphy Imaging of 99mTc-MAA During the Radioembolisation Pretreatment Procedure
To establish the safety and feasibility of interventional x-ray and scintigraphy imaging during the pre-treatment procedure of hepatic radioembolization
- Trial name
- IXSI (NCT06013774)
- Testing
- IXSI
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- UMC Utrecht
Hemophilia A, Hemophilia B
Ultrasonography in Hemophilic Joint Disease and Serum Markers
Hemophilia is a bleeding disorder (deficiency of a blood clotting factor/ protein) resulting in bleeding in joints and muscles. As patients continue to bleed into their joints they develop progressive joint damage leading to…
- Conditions
- Hemophilia A, Hemophilia B, Hemarthroses
- Trial name
- NCT02634918
- Testing
- ultrasound
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Myocardial Infarction, Acute Coronary Syndrome
Acute Coronary Syndrome in Patients With COVID-19
The aim of this study was to find a clinical or laboratory parameter, that would help in distinguishing between COVID-19 patients with myocardial infarction (MI), who have an infarct-related artery (IRA) and therefore, require…
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, COVID-19, Myocardium; Injury
- Trial name
- ACS-COVID (NCT05732597)
- Testing
- Coronary angiography
- Where
- Bulgaria
- Volunteers
- 26 people
- Sponsor
- Bulgarian Cardiac Institute
Leukemia
Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00002785
- Testing
- filgrastim, asparaginase, cyclophosphamide
- Where
- 33 sites in United States, Australia and 1 more
- Sponsor
- Children's Oncology Group
Traumatic Coma
Brain Network Disruptions Related to Traumatic Coma
To provide a fine-grained description of the brain network dysfunctions induced by severe traumatic brain injury (TBI) or anoxic encephalopathy, that are responsible for the acute state of unarousable unawareness, named coma…
- Trial name
- Coma3D (NCT03482115)
- Testing
- PET examination with radiopharmaceutical drug [18F] DPA-714, MRI examination, Blood samples
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Acute Intestinal Ischemia
Radiological Findings in Primary Intestinal Ischaemia
To investigate which findings on a non-specific CT scan that predict acute primary intestinal ischaemia.
- Trial name
- NCT04361110
- Testing
- Computerized tomography scan of the abdomen
- Volunteers
- 130 people
- Sponsor
- Aalborg University Hospital
Esophageal Cancer
S-1 Plus Nedaplatin With Concurrent Radiotherapy for Advanced Esophageal Cancer
Patients with advanced esophageal cancer will receive thoracic radiation therapy 60Gy over 30 fractions,and concurrent with s-1 and nedaplatin.
- Trial name
- NCT01175460
- Testing
- S-1, Nedaplatin
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Zhejiang Cancer Hospital
Surgical Wound
Photobiomodulation in Palate Wounds: Somatosensorial Evaluation
The goal of this clinical trial is to compare the effects of photobiomodulation with red laser on gingival graft donor areas of the palate in comparison to only protection with wound dressing.
- Trial name
- NCT06073678
- Testing
- Photobiomodulation, Protection with surgical dressing
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Gastric-type Endocervical Adenocarcinoma
Surgical Resection Enhances Survival in Gastric-type Endocervical Adenocarcinoma: A SEER-Based Study
This retrospective cohort study analyzes the effect of surgical resection on survival outcomes in patients with gastric-type endocervical adenocarcinoma (GAS), using data from the SEER database (2000-2021).
- Trial name
- SURGE (NCT07026825)
- Volunteers
- 308 people
- Sponsor
- Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center
Taste, Altered
Efficacy of Zinc on Concurrent Chemo-radiotherapy Induced Taste Alterations
Taste changes are common in cancer patients receiving concurrent chemoradiation which become a significant complaint and a cause of distress and morbidity.
- Trial name
- NCT03824925
- Testing
- Zinc Sulfate 220 MG
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Venous Leg Ulcers
Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers
This study is being done to find out if an investigational product called HP802-247 can help people with venous leg ulcers. Investigational means that HP802-247 has not been approved by the U.S.
- Trial name
- NCT01656889
- Testing
- HP-802-247, Vehicle
- Where
- 50 sites in United States, Canada
- Volunteers
- 447 people
- Sponsor
- Healthpoint
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