Clinical trials: Ropivacaine
Breast Surgery
Erector Spinae Versus Paravertebral Nerve Blocks for Breast Surgery
Following painful surgical procedures of the breast, postoperative analgesia is often provided with a paravertebral nerve block (PVB).
- Trial name
- NCT03549234
- Testing
- Erector Spinae (single injection), Paravertebral (single injection)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
Anesthesia
The Effectiveness of the Addition of Dexmedetomidine to Analgesia for Ankle Surgery.
Forefoot surgeries involve a relatively short operation usually completed in 1 - 1½ hours, with patients generally being allowed to go home on the same day.
- Trial name
- NCT02170948
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
Cardiac Disease, Surgery
Parasternal Block Combined With Rectus Sheath Block for Cardiac Surgery Under Sternotomy
The aim of this randomized controlled trial is to examine the effect of ultrasound guided bilateral Parasternal Nerve Block combined with rectus sheath block on preoperative analgesia, opioid consumption and respiratory function…
- Conditions
- Cardiac Disease, Surgery, Analgesia, Acute Pain
- Trial name
- PARARECTUS (NCT05764616)
- Testing
- PARASTERNAL BLOCK, LOCAL INFILTRATION OF DRAINAGE EXIT SITES, RECTUS SHEATH BLOCK
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Campus Bio-Medico University
Pain, Surgery
(TAP) Block vs. Systemic Lidocaine: Effects on Recovery
It has been demonstrated that female patients have poor quality of surgical recovery compared to male patients. Increased sensitivity to pain and increased susceptibility to postoperative nausea and vomiting have been attributed…
- Trial name
- TAP (NCT02053558)
- Testing
- Systemic lidocaine, TAP BLOCK with ropivacaine
- Sponsor
- Northwestern University
New Onset Atrial Fibrillation, Anesthesia, Local
Paravertebral Block to Reduce the Incidence of New Onset Atrial Fibrillation After Cardiac Surgery
The purpose if this pilot study is to determine if a perioperative infusion of 0.2% ropivacaine via bilateral T3 paravertebral catheters can decrease the incidence of new onset atrial fibrillation following primary CABG and/or…
- Conditions
- New Onset Atrial Fibrillation, Anesthesia, Local, Cardiac Disease
- Trial name
- NCT04472299
- Testing
- Ropivacaine 0.2% Injectable Solution
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Minnesota
Other Reconstructive Surgery
Clonidine in Femoral Nerve Block Surgery in Children
Knee arthroscopy is a common surgical procedure in pediatrics in which the knee joint is visualized through a small camera to help diagnose and treat knee problems.
- Trial name
- NCT01293149
- Testing
- Ropivacaine, Clonidine
- Where
- United States
- Sponsor
- Nationwide Children's Hospital
Nerve Block, Thoracoscopic Radical Resection of Lung Cancer
Analgesic Effects of Retro-superior Costotransverse Ligament Space Block for Video-assisted Thoracoscopic Surgery
The aim of this clinical trial is to investigate the effects of postoperative analgesia during retro-SCTLB(retro superior costotransverse ligament space block) and TPVB(thoracic paravertebral block) in patients undergoing…
- Trial name
- NCT07745881
- Testing
- Ultrasound-guided retro-SCTLB, Ultrasound-guided TPVB
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Pain, Postoperative, Regional Block
Perioperative Erector Spinae Plane Block in Thoracoscopic Surgery
The erector spinae plane block (ESPB) is a novel myofascial plane block. The ESPB is targeted at anterior surface of the erector spinae plane, which is oriented cephalocaudally to the spinal transverse process.
- Trial name
- NCT03777592
- Testing
- erector spinae plane block
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Kangbuk Samsung Hospital
Shoulder Pain, Opioid Use
Multimodal Analgesia in Shoulder Arthroplasty
Opioid medications are associated with many side effects and the risk of abuse or overdose. Orthopaedic surgeons are currently investigating ways to control pain after surgery while limiting the amount of opioid medications…
- Trial name
- NCT03586934
- Testing
- Acetaminophen, Celecoxib 200mg, Celecoxib 400 mg
- Where
- United States
- Sponsor
- Rush University Medical Center
Anesthesia, Local
Effective Use of Pecs and Transversus Thoracics Plane Blocks for Subcutaneous Cardiac Pacemaker Insertion: A Case Series
Participants that undergo permanent cardiac pacemaker implantation can often present with challenging anesthetic management plans for the anesthesia provider.
- Trial name
- NCT03899701
- Testing
- PEC I and PEC II blocks
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Anesthesia, Myomectomy
Improved Recovery Using Multimodal Peri-operative Analgesia in Minimally Invasive Myomectomy
The purpose of this study is to evaluate a multimodal analgesic protocol used in minimally invasive surgery for myomectomies (laparoscopic myomectomy (LM) and laparoscopically assisted myomectomy (LAM)).
- Trial name
- NCT00978601
- Testing
- Multimodal analgesic protocol during minimally invasive myomectomy
- Where
- Greece
- Volunteers
- 95 people
- Sponsor
- Iakentro Fertility Centre
Tourniquet Hypertension
A Long Axis Approach to the Femoral Artery Block (FAB) for Managing Tourniquet Pain and Hypertension in Below-the-Knee Fracture Surgery
This is a prospective, randomized, double-blind controlled trial evaluating an ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a control group.
- Trial name
- FAB (NCT07548567)
- Testing
- Femoral artery block - short-axis, Femoral artery block - long-axis, Normal saline injection (control)
- Where
- Greece
- Volunteers
- 84 people
- Sponsor
- National and Kapodistrian University of Athens
Anesthesia, Local
Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population
The primary aim of this study is to evaluate the pharmacokinetics of serum ropivacaine concentrations following erector spinae plane peripheral nerve blocks in the pediatric population.
- Trial name
- NCT04298099
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Baylor College of Medicine
Pain, Postoperative, Hysterectomy
Observational Retrospective Study on Spinal Analgesia in Laparoscopic and Laparotomic Hysterectomy
Perioperative multimodal analgesia, defined by the use of various analgesic medications targeting different drug receptors, provides adequate pain relief with minimal or no opiate consumption.
- Conditions
- Pain, Postoperative, Hysterectomy, Morphine, Anesthesia, Spinal
- Trial name
- SPIN_GYN (NCT05654363)
- Testing
- Administration of morphine by intrathecal route, Administration of morphine by intravenous route
- Where
- Italy
- Volunteers
- 670 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hip Dysplasia, Hip Disease
The Effect of Dexamethasone Administration Route in PENG Block for Pediatric Hip Surgery
This study aims to assess the impact of the administration route of dexamethasone (intravenous vs. perineural) on postoperative pain, inflammatory response, and neuromonitoring parameters in pediatric patients undergoing hip…
- Trial name
- NCT06789367
- Testing
- perineural Dexamethasone 4mg, intravenous Dexamethsone 4mg
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Head and Neck Cancer, Free Tissue Transfer
Local Infusion of Ropivacaine for Post-Op Pain Control After Osseocutaneous Free Flaps
Head and neck oncologic surgery often requires the use of free tissue transfer, or microvascular reconstruction, to reconstruct defects created by tumor resections.
- Trial name
- NCT03349034
- Testing
- Ropivicaine, Local Saline Infusion
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anorectal Surgery, Pain Management
A Multidisciplinary Perioperative Pain Management
Objective: This study aimed to evaluate the clinical value of a multidisciplinary collaboration (MDC)-based perioperative pain management model.
- Trial name
- NCT07150819
- Testing
- Standard Nursing Care Protocol, MDC-based Pain Management
- Where
- China
- Sponsor
- China-Japan Friendship Hospital
Cardiac Valve Disease, Coronary Heart Disease
Superficial Parasternal Block Combined With Rectus Sheath Block for Open Cardiac Surgery
The investigators will examine whether the combination of a superficial parasternal block and rectus sheath block with multimodal analgesia can enhance postoperative pain control and reduce opioid administration when compared to…
- Trial name
- NCT07890857
- Testing
- Parasternal and rectus sheath block, ropivacaine 0.25 %
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Hôpital du Valais
Analgesia
NOL-Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block
This clinical trial focuses on an elaborate, propensity-matched, non-inferiority comparison of NOL-guided Superficial Parasternal Intercostal Plane Block (SPIPB) and Erector Spinae Plane Block (ESPB) within the context of…
- Trial name
- NESP-II (NCT06070701)
- Testing
- Superficial Parasternal Block (SIPB), Erector Spinae Plane Block (ESPB), General anesthetic
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Degenerative Osteoarthritis
Continuous Distal Adductor Canal Block With Periarticular Local Anesthetic Infiltration Versus Continuous Distal Adductor Canal Block Alone for Analgesia After Total Knee Arthroplasty
Continuous administration of local anesthetics to the distal adductor canal could spread into the popliteal fossa and contribute to analgesic effects on posterior knee pain.
- Trial name
- NCT05427019
- Testing
- Distal adductor canal block, Distal adductor canal block and Periarticular block
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
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