Clinical trials: Ropivacaine
Knee Arthroscopy, Acute Pain
"Comparison of Intra-articular of 0.2% Ropivacaine vs. 0.75% Ropivacaine in Postoperative of Knee Arthroscopy"
All patients with acute lesions that attend the orthopedic and trauma center of the ABC medical center are invited to participate in the study.
- Trial name
- ropivacaine (NCT05807945)
- Testing
- Ropivacaine 0.75% Injectable Solution, Ropivacaine 0.2% Injectable Solution
- Where
- Mexico
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Paola M Zamora Munoz
Analgesia
Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block
In 2012 Blanco et al. [1] described the ultrasound technique for Pectoral nerve (PECS) block as a new, less invasive regional analgesic technique for breast surgeries.
- Trial name
- NCT06636578
- Testing
- dexmedetomidine, ropivacaine, fentanyl
- Where
- 2 sites in Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Phrenic Paralysis, Shoulder Joint Surgery
The Effect of Brachial Plexus Block on Diaphragm Movement
The purpose of this study is to quickly evaluate the degree of phrenic nerve block by observing the changes of diaphragm movement through ultrasound, and to find the best scheme for clinical application by controlling the…
- Conditions
- Phrenic Paralysis, Shoulder Joint Surgery, Rotator Cuff Injury
- Trial name
- NCT06640621
- Testing
- Different concentration of ropivacaine for single brachial plexus block
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Traumatic Rib Fracture(s)
Rib Fracture Analgesia Using Cryoanalgesia
Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to…
- Trial name
- NCT04198662
- Testing
- Cryoneurolysis with a Painblocker (Epimed International, Farmers Branch, Texas), Intercostal nerve block ropivacaine with epinephrine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Anesthesia, Spinal, Neurosurgery
Testing the Feasibility of Using Ropivacaine in Spinal Anesthesia for Patients With Lower Back Surgery
The goal of this pilot clinical trial is to test the feasibility of conducting a randomized controlled trial that will examine the use of ropivacaine in the spinal anesthesia for patients undergoing elective 1- or 2-level lower…
- Conditions
- Anesthesia, Spinal, Neurosurgery, Ropivacaine, Bupivacaine
- Trial name
- SASS (NCT05824338)
- Testing
- Spinal anesthesia for lumbar surgery: ropivacaine, Spinal anesthesia for lumbar surgery: bupivacaine, General anesthesia for lumbar surgery
- Where
- 2 sites in Canada
- Volunteers
- 45 people
- Sponsor
- Fraser Health
Knee Osteoarthritis, Knee Pain Chronic
Erector Spinae Plane Block Vs. IPACK Block with Adductor Canal Block for Total Knee Arthroplasty
Effect of Erector Spinae Plane Block and iPACK block with Adductor Canal Block on pain management, and NLR and PLR following knee arthroplasty
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT06233630
- Testing
- Control Test - spinal anesthesia, Ropivacaine 0.2% Injectable Solution ESPB, Ropivacaine 0.2% Injectable Solution iPACK+ACB
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Dexmedetomidine, Fascia Iliaca Block
Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery
To examine the impact of various administration routes of dexmedetomidine in conjunction with ultrasound-guided fascia iliaca block (FIB) on emergence agitation (EA) during the postoperative recovery period after hip replacement…
- Trial name
- NCT06614010
- Testing
- Dexmedetomidine Injection, Ropivacaine and Dexmedetomidine, Sodium Chloride Injection
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Qianfoshan Hospital
Liposomal Bupivacaine, Postoperative Recovery
A Analgesic Study of Adductor Canal &IPACK Block with Liposomal Bupivacaine in Knee Arthroplasty
To study the effectiveness of ACB and iPACK block with liposomal bupivacaine for postoperative analgesia in patients undergoing knee arthroplasty
- Conditions
- Liposomal Bupivacaine, Postoperative Recovery, Unilateral Knee Arthroplasty
- Trial name
- NCT06145165
- Testing
- Nerve block with ropivacaine and intravenous analgesia, Nerve block with liposomal bupivacaine and intravenous analgesia, Intravenous analgesia
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Breast Neoplasms
The Application of Pectoral Nerve II(PECS II)block in Breast Fibroadenoma Resection Surgery
Patients were randomly assigned to the GA group, PECS II group, or TPVB group using a computer-generated random number table. Group assignments were kept in a sealed envelope, which was opened only after induction of general…
- Trial name
- PECS II (NCT06608810)
- Testing
- nerve block with 0.5% ropivacaine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Inner Mongolia Baogang Hospital
Cesarean Section
A Randomized Controlled Trial Comparing Intrathecal Morphine With Quadratus Lumborum Block for Post-cesarean Delivery Analgesia
Pain after caesarean delivery (CD) can interfere with the moms' ability to look after her baby and may contribute to developing long term pain and disability.
- Trial name
- NCT02871713
- Testing
- Bilateral Quadratus lumborum block with 0.5% ropivacaine, Intrathecal Morphine with 100 mcg morphine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Nova Scotia Health Authority
Anesthetics, Local
Split Face Study of the Duration of Local Anesthetics
This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for.
- Trial name
- NCT05767749
- Testing
- lidocaine + epinephrine 1:100,000, Ropivacaine 0.5% Injectable Solution, Bupivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Bunion
A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain
PRF-110 is a viscous, yellowish clear oily solution of ropivacaine intended for administration into surgical sites to provide post-operative analgesia.
- Trial name
- NCT05773846
- Testing
- Ropivacaine
- Where
- 7 sites in United States
- Volunteers
- 428 people
- Sponsor
- PainReform LTD
Post-operative Pain
Intrathecal Morphine vs. Intrathecal Morphine and Regional Anesthesia After Cesarean Section.
The objective of the study is to optimize post-operative analgesia and improve patient satisfaction while reducing total opioid consumption after cesarean section
- Trial name
- NCT06114121
- Testing
- erector spinae plane block (ESP), Duramorph, Ropivacaine
- Sponsor
- University of Miami
Local Anesthesia Adjuvants, Upper Extremity Fracture
Effect of Dexmedetomidine As Adjuvant to Ropivacaine for Brachial Plexus Block
Brachial plexus block is used for upper limb surgery. Local anesthesia alone for brachial plexus block provides good operative conditions, but have short duration of postoperative analgesia.
- Conditions
- Local Anesthesia Adjuvants, Upper Extremity Fracture, Brachial Plexus Block
- Trial name
- NCT05767827
- Testing
- ropivacaine, lidocaine with adrenaline, Dexmedetomidine, ropivacaine, lidocaine with adrenaline
- Where
- Nepal
- Volunteers
- 40 people
- Sponsor
- Nepal Medical College and Teaching Hospital
Hallux Valgus
Magnesium as Adjuvant for Sciatic Block
The aim of the study is to evaluate if Magnesium added to ropivacaine can reduce onset time and can enhance offset time.
- Trial name
- Mg (NCT02198547)
- Testing
- Magnesium Sulfate, Ropivacaine
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
Postoperative Pain
Analgesic Efficacy of an Opioid-free Postoperative Pain Management Strategy Versus a Conventional Opioid-based Strategy Following Video-assisted Thoracoscopic Lobectomy
Investigators have designed a randomized controlled trial. Utilizing an open-label, randomized, controlled study methodology, this trial aims to explore a opioid-free, safe, and effective analgesic approach for thoracic surgery.
- Trial name
- NCT06570538
- Testing
- Ropivacaine, Sufentanil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Postoperative Analgesia
Intravenous Paracetamol in Combination With Caudal Ropivacaine
To investigate whether the addition of intravenous paracetamol with caudal ropivacaine leads to better quality of postoperative recovery in patients undergoing hypospadius repair than caudal ropivacaine alone.
- Trial name
- NCT03781505
- Testing
- Paracetamol +caudal ropivacaine
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Aga Khan University
Paravertebral Block, QT Interval
Influence of Thoracic Paravertebral Block on Cardiac Repolarization
Aim of the study is to determine the presence and direction of electrocardiographical changes of cardiac repolarization after thoracic paravertebral block, depending on block laterality.
- Trial name
- NCT05822076
- Testing
- Paravertebral block (ropivacaine) left, Paravertebral block (ropivacaine) right
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
Prospective, Randomized
The Analgesic Efficacy of Pericapsular Nerve Group (PENG) Block in Patients Undergoing Primary Total Hip Arthoplasty:
The aim of this study is to investigate the analgesic efficacy of the pericapsular nerve group (PENG) block during the implantation of hip endoprostheses.
- Conditions
- Prospective, Randomized, Double-blind
- Trial name
- PENG (NCT06557044)
- Testing
- Ropivacaine, Physiological saline
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Postoperative Analgesia, Quality of Recovery
Effect of SNB on the QoR in Patients Undergoing Supratentorial Tumor Resection
Patients with Supratentorial tumor undergoing craniotomy have a higher risk of postoperative pain, which will affect their postoperative quality of recovery (QoR).
- Conditions
- Postoperative Analgesia, Quality of Recovery, Supratentorial Tumor, Craniotomy
- Trial name
- NCT06157359
- Testing
- scalp nerve block
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine