Clinical trials: Ropivacaine
Peripheral Nerve Block, Pain
The Analgesic Effect of Combined Nerve Block and Systemic High Dose Glucocorticoid After Total Knee Arthroplasty.
Purpose: The purpose of this study is to evaluate the postoperative analgesic effect of a combined Saphenous nerve block and Obturator nerve block with local infiltration analgesia in the tissue around the knee after total…
- Trial name
- HOBSALIplus (NCT02374008)
- Testing
- Ropivacaine
- Volunteers
- 74 people
- Sponsor
- Regionshospitalet Silkeborg
Pain
Continuous Wound Infiltration for Diminution of Post-surgery Pain After Caesarean Section
A medical approach that warrants continuous and reliable local administration of non-opioid analgesic drugs might substantially improve post-surgery pain management in CS, while decreasing the necessity of staff-dependent…
- Trial name
- dip-Caesar (NCT02828059)
- Testing
- Ropivacaine
- Sponsor
- Jena University Hospital
Hemorrhoids
Ligasure Versus Diathermy Haemorrhoidectomy Under Local Anesthesia
The objective of this prospective randomised trial was to compare the short- and long-term efficacy of conventional diathermy haemorrhoidectomy versus Ligasure™ diathermy, and to assess the short-term outcome of each procedure…
- Trial name
- LDHLA (NCT00617448)
- Testing
- diathermy haemorrhoidectomy under espinal anesthesia, diathermy haemorrhoidectomy under local anesthesia, Ligasure haemorrhoidetomy under spinal anestesia
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Hospital de Viladecans
Analgesia
Quadratus Lumborum Block After Living Donor Kidney Transplantation
The aim of this study is to evaluate the postoperative analgesic effect of quadratus lumborum block in patient undergoing a living donor kidney transplant under general anesthesia.
- Trial name
- NCT04908761
- Testing
- Transmuscular quadratus lumborum block
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Seoul National University Hospital
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
Anesthesia, Surgery
Assessment of Systemic Pharmacokinetics of Levobupivacaine and Ropivacaine During Continuous Epidural Infusion
The aim of the study is the assessment of the systemic absorption of local anesthetics during continuous epidural infusion for postoperative pain control.
- Trial name
- LEVOROPI (NCT01229241)
- Testing
- local anesthetic
- Where
- 2 sites in Italy
- Volunteers
- 181 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Osteoarthritis, Hip, Hip Osteoarthritis
Intravenous Dexamethasone (0 vs 4 vs 8 mg) as an Adjunct to PENG Block for Postoperative Analgesia in Total Hip Arthroplasty
his study will test whether giving dexamethasone through a vein can improve pain control after total hip replacement surgery. Dexamethasone is commonly used to reduce nausea and may also help with pain, but it is not clear which…
- Trial name
- NCT07581470
- Testing
- Dexamethasone 4mg, Dexamethasone 8mg
- Where
- Poland
- Volunteers
- 198 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis Shoulder
Diaphragm-Sparing Regional Anesthesia Techniques for Shoulder Surgery
This study will compare two regional anesthesia techniques for shoulder surgery and evaluate their effects on diaphragmatic function.
- Trial name
- NCT07474896
- Testing
- Ropivacaine 0.2% for Interscalene Block, Ropivacaine 0.2% for Infraclavicular and Suprascapular Nerve Blocks
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Poznan University of Medical Sciences
Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time
Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children
The investigators intend to study the safety and effectiveness of opioid free anesthesia compared to opioid anesthesia in ambulatory surgery in children, regarding postoperative pain, hemodynamic stability, agitation and…
- Conditions
- Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time, Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit, Effect of Anesthesia in Postoperative Adverse Events
- Trial name
- NCT03979469
- Testing
- Ketamine, dexmedetomidine, fentanyl, remifentanil
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Knee Osteoarthritis, Knee Arthritis
Pain Management After Adductor Canal Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial sought to evaluate the efficacy of the iPACK block with Adductor Canal Block on postoperative pain, functional recovery and NLR and PLR levels.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Arthropathy, Knee Pain Chronic
- Trial name
- NCT06086483
- Testing
- Ropivacaine 0.2% Injectable Solution, 0.9%sodium chloride
- Where
- Poland
- Volunteers
- 361 people
- Sponsor
- Poznan University of Medical Sciences
Low Back Pain
A Trial Comparing Three Orthobiologic Therapies on Atrophied Multifidus Muscles in Patients With Low Back Pain
To evaluate and compare the effectiveness of 3 different injection treatments on multifidus atrophy and lower back pain.
- Trial name
- NCT03618979
- Testing
- PPP treatment, PRP treatment, PRP and PL Combo treatment
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Regenexx, LLC
Surgery of Abdominoplasty With Flank Liposuction
Analgesic Effect Between TAP Block and Continuous Wound Infusion in Abdominoplasty Surgery
The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of…
- Trial name
- NCT01862354
- Testing
- Transverse abdominal plan block, Continuous wound infusion
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege
Nerve Block, Anesthesia, Local
Sensory Distribution of Lateral Femoral Cutaneous Nerve Block
The purpose of this study is to investigate and describe the anatomical distribution of the sensory outcome following LFCN block (LFCN = lateral femoral cutaneous nerve) in relation to the incisional lines after Total Hip…
- Conditions
- Nerve Block, Anesthesia, Local, Pain, Postoperative, Anatomical Distribution
- Trial name
- NCT02957903
- Testing
- Ropivacaine, Isotonic Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Benign Female Reproductive System Neoplasm
Efficacy and Safety of Parecoxib on Morphine Patient-controlled Epidural Analgesia (PCEA) After Gynecologic Surgery
The purpose of this study is to determine the effects of parecoxib in combination with epidural morphine in providing analgesia for patients undergoing gynecological surgery.
- Trial name
- PCEA (NCT01566669)
- Testing
- Parecoxib Sodium, Normal saline
- Where
- China
- Volunteers
- 294 people
- Sponsor
- Liu Weifeng
Pain Management, Nerve Block
Transmuscular Quadratus Lumborum Block for Postoperative Pain After Laparoscopic Adrenalectomy
This prospective, randomized control study aims to compare the analgesic effect, satisfaction with anesthesia and analgesia between single-injection QLB (quadratus lumborum block)+general anesthesia (GA) and general anesthesia…
- Conditions
- Pain Management, Nerve Block, Laparoscopic Adrenalectomy
- Trial name
- NCT03942237
- Testing
- single-injection QLB(quadratus lumborum block)
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking Union Medical College Hospital
Knee Osteoarthritis
ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty
This study will compare two regional anesthesia strategies for pain management after total knee arthroplasty in adults. Both strategies use an adductor canal block (ACB) to provide analgesia while preserving quadriceps muscle…
- Trial name
- NCT07288970
- Testing
- Adductor Canal Block, Sacral Erector Spinae Plane Block, iPACK Block
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Medical Sciences
Adverse Effect, Feasibility Study
Feasibility and Safety of Sciatic Nerve Paraneural Sheath Block Using a Mid-Femoral Lateral Approach
This study is designed as a randomized controlled trial aiming to evaluate the feasibility and safety of ultrasound-guided mid-femoral lateral approach sciatic nerve paraneural sheath block, in order to provide a new sciatic…
- Conditions
- Adverse Effect, Feasibility Study, Safety and Effectiveness
- Trial name
- iSNB-LF (NCT07366853)
- Testing
- Ultrasound-guided lateral mid-femoral sciatic nerve block, Ultrasound-guided popliteal sciatic nerve block
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Tibial Plateau Fracture, Pain, Postoperative
Saphenous Nerve Block After Tibial Plateau ORIF
Fractures of the tibial plateau, while very painful, typically do not receive nerve blocks. This is because of a concern that the numbness from a nerve block would "mask" the typically painful symptoms of compartment syndrome, a…
- Trial name
- NCT04314570
- Testing
- Saphenous Nerve Block with Ropivacaine Treatment, Saphenous Nerve Block with Saline Control
- Sponsor
- Stanford University
Arterio-venous Fistula
NIRS Measurement After SCP Block
Peripheral regional anesthesia induces a sympathectomy-like effect with neurovascular changes causing increased arterial blood flow and venodilatation .
- Trial name
- NCT03044496
- Testing
- Supraclavicular nerve block
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Marienhospital Stuttgart
Conduction Abnormalities, Paravertebral Anesthesia
Influence of Thoracic Paravertebral Block on Atrioventricular Conduction
The aim of the study is to assess the changes in electrical activity of heart atria and in atrioventricular conduction induced by anaesthetic thoracic paravertebral blockade, depending on site on which blockade was performed.
- Trial name
- NCT06833086
- Testing
- Paravertebral block (ropivacaine) left, Paravertebral block (ropivacaine) right
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
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